BIOGRAPHICAL SKETCH Prof. Georg Nickenig

Nickenig, Georg:
Excellence Cluster for ImmunoSensation
BIOGRAPHICAL SKETCH
Prof. Georg Nickenig, MD
Universitätsklinikum Bonn. Director, Medizinische Klinik und Poliklinik II
E-mail: [email protected]
Research Expertise
•
Pathophysiology of atherosclerosis
•
Molecular and cellular mechanisms of endothelial dysfunction
•
Vascular regeneration
•
Clinical research on coronary heart disease and valve disease
Education / Training
Institution and Location
Major
University of Cologne, Germany
Internal Medicine-Cardiology
University of Bonn, Germany
Clinical Medicine
University of Bonn, Germany
Clinical Medicine
Appointments / Positions Held
Year
Position
2005 – present
Full Professor and Chair, Medizinische Klinik
und Poliklinik II, Cardiology, Pneumology,
Angiology, Universitätsklinikum Bonn
2000 - 2005
Professor of Cardiology, Klinik und Poliklinik
Innere Medizin III
1996 - 2000
Fellow-ship cardiology, molecular cardiology
research, Medizinische Klinik III
1995
Postdoctoral fellow, Internal Medicine
Medizinische Poliklinik
1993 - 1994
Postdoctoral research fellow-ship at Medical
School Emory, Dept. of Cardiology and
Pharmacology
1989 - 1992
Internship, Residency Internal Medicine
Degree, Year
Habilitation, 2000
MD thesis, 1990
MD, 1989
Institution
University of Bonn, Germany
University of Saarland, Bad
Homburg, Germany
University of Cologne,
Germany
University of Bonn, Germany
University of Atlanta, USA
University of Bonn, Germany
Honors / Awards
2004
2001
2001
1999
1999
1997
1997
1996
1996
1996
Albert-Fraenkel-Preis der Deutschen Gesellschaft für Kardiologie
Theodor-Frerichs-Preis der Deutschen Gesellschaft für Innere Medizin
NOVARTIS Preis für therapierelevante pharmakologische Forschung
Irbesartan Research Award
Young Investigator Award of the European Vascular Biology Society
Forschungspreis der Deutschen Herzstiftung
Dieter Klaus Preis für Hypertonieforschung
Präventionspreis der Deutschen Herzhilfe
H. u. G. Meise Preis der Dt. Gesell. für Reha.-und Präventionsmedizin
Oskar Lapp Preis der Deutschen Gesellschaft für Kardiologie
Hartmann, Gunther:
Excellence Cluster for ImmunoSensation
10 Most Relevant Publications for Prof. Georg Nickenig
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Strehlow K, Werner N, Berweiler J, Link A, Dirnagl U, Priller J, Laufs K, Ghaeni L, Milosevic
M, Böhm M, Nickenig G. Estrogen increases bone marrow-derived endothelial progenitor cell
production and diminishes neointima formation. Circulation 2003;107:3059-65
Wassmann S, Stumpf M, Strehlow K, Schmid A, Schieffer B, Böhm M, Nickenig G.
Interleukin-6 induces oxidative stress and endothelial dysfunction by overexpression of the
angiotensin II type 1 receptor. Circ Res 2004;94(4):534-541
Wassmann S, Czech T, van Eickels M, Fleming I, Böhm M, Nickenig G. Inhibition of dietinduced atherosclerosis and endothelial dysfunction in apolipoprotein E / angiotensin II type
1A receptor double-knockout mice. Circulation 2004;110(19):3062-3067
Werner N, Kosiol S, Schiegl T, Ahlers P, Walenta K, Link A, Böhm M, Nickenig G. Circulating
endothelial progenitor cells predict cardiovascular morbidity and mortality in patients with
coronary artery disease. The Endothelial Progenitor Cells in Coronary Artery Disease
(EPCAD) Study. N Engl J Med, 2005;353:999-1007
Mueller CF, Wassmann K, Widder JD, Wassmann S, Chen CH, Keuler B, Kudin A, Kunz WS,
Nickenig G. Multidrug resistance protein-1 affects oxidative stress, endothelial dysfunction,
and atherogenesis via leukotriene C4 export. Circulation 2008; 117(22):2912-8
Hofmann A, Wenzel D, Becher UM, Freitag DF, Klein AM, Eberbeck D, Schulte M,
Zimmermann K, Bergemann C, Gleich B, Roell W, Weyh T, Trahms L, Nickenig G,
Fleischmann BK, Pfeifer A.Combined targeting of lentiviral vectors and positioning of
transduced cells by magnetic nanoparticles. Proc Natl Acad Sci U S A. 2009 Jan
6;106(1):44-9
Rudolph V, Andrié RP, Rudolph TK, Friedrichs K, Klinke A, Hirsch-Hoffmann B, Schwoerer
AP, Lau D, Fu X, Klingel K, Sydow K, Didié M, Seniuk A, von Leitner EC, Szoecs K, Schrickel
JW, Treede H, Wenzel U, Lewalter T, Nickenig G, Zimmermann WH, Meinertz T, Böger RH,
Reichenspurner H, Freeman BA, Eschenhagen T, Ehmke H, Hazen SL, Willems S, Baldus S.
Myeloperoxidase acts as a profibrotic mediator of atrial fibrillation. Nat Med. 2010
Apr;16(4):470-4
Zimmer S, Steinmetz M, Asdonk T, Motz I, Coch C, Hartmann E; Barchet W, Wassmann S,
Hartmann G, Nickenig G. Activation of endothelial toll-like receptor 3 impairs endothelial
function. Circ Res 2011; 108(11):1358-66
Zimmer S, Steinmetz M, Asdonk T, Motz I, Coch C, Hartmann E, Barchet W, Wassmann S,
Hartmann G, Nickenig G. Activation of endothelial toll-like receptor 3 impairs endothelial
function. Circ Res. 2011;108(11):1358-1366
Sinning JM, Hammerstingl C, Vasa-Nicotera M, Adenauer V, Lema Cachiguango SJ, Scheer
AC, Hausen S, Sedaghat A, Ghanem A, Müller C, Grube E, Nickenig G, Werner N. Aortic
regurgitation index defines severity of peri-prosthetic regurgitation and predicts outcome in
patients after transcatheter aortic valve implantation. J Am Coll Cardiol. 2012;59(13):113441