Project Description EXC 306: Inflammation at Interfaces - Gepris

EXC 306: Inflammation at Interfaces
Subject Area
Term
Microbiology, Virology and Immunology
since 2007
Project identifier
Deutsche Forschungsgemeinschaft (DFG) - Projekt number 49701054
Project Description
Inflammation at barrier organs (skin, lung, gut) is a central medical problem including many civilisation diseases such
as asthma and chronic inflammatory bowel disease. The vision of the cluster of excellence is that barrier problems
may be causally involved in many other systemic inflammatory (e.g. coronary heart disease) and malignant (e.g.
colorectal carcinoma) disorders.
To improve the multidisciplinary study of barrier disorders, the cluster of excellence will restructure research at five
faculties at the universities of Kiel and Lübeck and the Research Center Borstel, Leibniz-Center for Medicine and
Biosciences. Twenty-nine principal investigators and 108 additional excellent scientists have established five contentand method-defined research areas by joining their individual research operations, which together will streamline the
scientific processes of the investigation of diseases from genomic discovery to model-system based mechanistic
understanding and its validation at the patient level. This leads to a new quality of multidisciplinary research
translating a synergistic generation of knowledge around etiologically relevant molecule families into application in
inflammatory barrier diseases and their treatment.
The research environment forms the basis of an innovative concept of interdepartmental postgraduate education
(medicine/life sciences). The applicant institutions have committed to the inauguration of 21 new professorships and
departments to complement and strengthen the research environment. The multidisciplinary structure of the cluster of
excellence provides the scientific environment for twelve new independent junior research groups ensuring early
independence and promoting gender-equality of young scientists. Finally, the establishment of a clinical
"Comprehensive Center for Inflammation Medicine" (CCIM) ensures a permanent, multidisciplinary integration
between different clinical sub-disciplines and basic research; in addition it facilitates the cooperation with industry.
DFG Programme
Participating subject areas
Clusters of Excellence
Biochemie, Dermatologie, Entzündungsmedizin,
Epidemiologie, Evolutionsgenetik, Infektiologie,
Strukturbiologie, Pneumologie, Molekularbiologie,
Gastroenterologie, Immunologie,
Ernährungswissenschaften
Applying institution
Christian-Albrechts-Universität zu Kiel
24098 Kiel
Co-applicant institution
Universität zu Lübeck
Ratzeburger Allee 160
23562 Lübeck
Participating institution
Forschungszentrum Borstel
Leibniz-Zentrum für Medizin und Biowissenschaften
Parkallee 1-40
23845 Borstel
Max-Planck-Institut für Evolutionsbiologie
August-Thienemann-Straße 2
24306 Plön
Spokesperson
Participating scientists
DFG programme contact
Professor Dr. Stefan Schreiber
Christian-Albrechts-Universität zu Kiel
Universitätsklinikum Schleswig-Holstein
Institut für Klinische Molekularbiologie
Rosalind-Franklin-Straße 12
24105 Kiel
Telephone: +49 431 50015101
Fax: +49 431 50015104
E-Mail: s.schreiber mucosa.de
Professor Dr. Thomas C. G. Bosch; Professor Dr. Stefan
Ehlers; Professorin Dr. Jeanette Erdmann; Professor Dr.
Rainer Ernst; Professor Dr. Andre Franke; Professor Dr.
Wolfgang L. Gross; Professor Dr. Rolf Hilgenfeld;
Professor Dr. Dietrich Kabelitz; Professor Dr. Jörg Köhl;
Professor Dr. Rudolf Manz; Professorin Almut Nebel,
Ph.D.; Professor Dr. Stefan Niemann; Professor Dr. Klaus
F. Rabe; Professor Dr. Gerald Rimbach; Professor Dr.
Stefan Rose-John; Professor Dr. Philip Caspar Rosenstiel,
Ph.D.; Professor Dr. Paul Saftig; Professor Dr. Ulrich E.
Schaible; Professor Dr. Jens-Michael Schröder; Professor
Dr. Stefan Schütze; Professor Dr. Reiner Siebert;
Professor Dr. Diethard Tautz; Professor Dr. Stephan
Weidinger; Professor Dr. Detlef Zillikens
Dr. Andreas Strecker
GEPRIS is a project of the Deutsche Forschungsgemeinschaft (DFG)
Contact GEPRIS at http://www.dfg.de/gepris
(c) 1999 - 2017 Deutsche Forschungsgemeinschaft (http://www.dfg.de)