multiple sclerosis

The Frequency Of Depression And Anxiety At Multiple Sclerosis Patients
Faculty of Medicine, University of Tuzla, 75000 Tuzla, Bosnia and Herzegovina
Department of Neurology, University Clinical Center Tuzla, 75000 Tuzla, Bosnia and
Contact e-mail: [email protected] Type of presentation: oral presentation
Introduction: Depression is the most common psychiatric disorder which can be found in MS
patients at frequency of 50%.
Aims: To determine frequency of depression and anxiety in people suffering from MS in relation
to age, gender, and duration of the disease.
Subjects and Methods: Perspective study included 64 subjects, 32 of them with MS diagnosis
and 32 subjects as part of the control group. Inquiry was done in the Association of MS patients
in Tuzla Canton, from January 16. to February 03. Becks inventor of anxiety and Becks inventor
of depression were used for the research. Statistical Software as Graphpad Prism, ANOVA test
and t-test with single and double direction, were used for calculating group differences.
Results : 42 women and 22 men (2:1) were included in the research, with equal distribution
among both groups of subjects. Average age of people suffering from MS is 46,78 (SD 10,33),
and in the control group the average age was 48,19 (SD 11,87);(p>0,5). Average depression in
people with MS was (4,9/56.25%, 17,3/9.4%, 23,7/18.75%, 39,4/15.6%), whereas within the
control group it was (4,6/90.6%, 16,33/9,4) which has a statistically significant difference
(p<0,001). There is a noticeable difference in amount of anxiety between the control group
(5,4/68.8%, 12,7/12.5%, 20,3/18,7%) and people with diagnosed MS (8/6.25%, 12,8/15.6%,
20,9/40.6%, 41,8/ 37.5%; p=0,0001), while there is no difference in terms of men and women
with MS diagnosis (p>0,05). By comparing the duration of disease with frequency of depression
no statistically significant difference is noticeable (p>0,05), while in terms of anxiety it is
significant (p=0,01), and most noticeable in subjects suffering from disease 11-20 years back
Conclusion : Results of this study point to a significant amount of depression and anxiety in MS
Key words: Multiple sclerosis, depression, anxiety, Becks inventory, disease