1 Prof. Ralf Henkel, PhD Curriculum vitae Prof. Dr. rer. nat. Ralf

Prof. Ralf Henkel, PhD
1
Curriculum vitae
Prof. Dr. rer. nat. Ralf Henkel, Ph.D.
Personal data:
15.06.1960 born as son of the technician Waldemar Henkel and his wife Helga Henkel
married to a South African citizen; 2 children
Course of education and occupation:
01.01.2008 Promotion to Senior Professor in the Department of Medical Biosciences at the
University of the Western Cape
01.09.2007 Regional co-ordinator for Africa of the Asian Journal of Andrology
01.01.2006 Deputy Chair of Department of the Department of Medical Biosciences at the
University of the Western Cape (Term: January 2006 until December 2008)
01.09.2005 Full Professor for Reproductive Biology and Research Coordinator at the
Department of Medical Biosciences of the University of the Western Cape,
Bellville, South Africa
18.01.2005 Member of the Editorial Board of the Asian Journal of Andrology
11.09.2004 till 31.11.2005
Member of the Executive Council of the German Society of Andrology
(responsible for research) (resigned because of leaving Germany and thus not
being available for local council meetings)
01.08.2004 till 31.08.2005
Full Professor (C3) for “Experimental Andrological Urology – Endocrinology” at
the Department of Urology of the Friedrich Schiller University, Jena, Germany;
(HOD: Prof. Dr. J. Schubert)
01.03.2004 till 31.07.2004
Appointed as Extraordinary Professor (apl. Prof.) of Reproductive Biology by the
President of the Justus Liebig University of Giessen.
01.01.2000 till 31.07.2004
Member of the Board of Directors of the Department of Dermatology and
Andrology.
16.12.1999 Appointed as Associate Professor (Hochschuldozent; C2) for “Reproductive
Biology” by the Hessian Minister of Science and Arts.
23.02.1999 till 31.07.2004
Appointed as Commissioner for Animal Protection at the Department of
Dermatology and Andrology.
11.05.1998 Appointment as Assistant Professor (Privatdozent)
02.02.1998 Habilitation for the subject ”Reproductive Biology” at the Faculty of Medicine of
the Justus Liebig University of Giessen, Germany
01.03.1995 till 22.03.1999
Appointed as Deputy Commissioner for Animal Protection at the Department of
Dermatology and Andrology.
Dec. 1994
Further employment at the Department of Dermatology and Andrology, University
of Giessen as head of Functional Diagnosis of Spermatozoa in Andrology
Dec. 1993
- Dec. 1994 Scholarship from the "Stifterverband für die Deutsche Wissenschaft" to work on
the project: "Human acrosome reaction: a study to standardize laboratory
Prof. Ralf Henkel, PhD
15.07.1993
Jan. 1992
Jan. 1991
15.07.1990
23.02.1990
1986 - 1990
27.11.1985
1979 - 1985
12.06.1979
1970 - 1979
1966 - 1970
2
procedures for evaluating the acrosomal reaction and to record the influence of
human zona pellucida moieties on the acrosome reaction." at the Department of
Obstetrics and Gynaecology, Reproductive Biology Unit, Tygerberg Hospital,
Tygerberg, South Africa; HOD: Prof. H.J.Odendaal, Heads of the Reprod. Biol.
Unit: Prof. T.F. Kruger, Prof. D.R. Franken
Head of Functional Diagnosis of Spermatozoa in Andrology at the Department of
Dermatology and Andrology, University of Giessen, Germany
Appointed with setup and management of the Laboratory of Reproductive
Medicine at the Department of Dermatology and Andrology of the Justus Liebig
University of Giessen, Germany
Appointed with the supervision of the Functional Diagnosis of Spermatozoa in
Andrology
Scientist at the Department of Dermatology and Andrology, Andrological
Research Unit of the Justus Liebig University of Giessen, Germany, (supported by
the "Gesellschaft zur Förderung der in vitro-Fertilisation G.b.R.", Giessen);
(HOD: Prof. Dr. Dr. med. habil. W.-B. Schill)
Examination for PhD degree
Thesis at the laboratory of Prof. Dr. C. Kirchner at the Philipps University of
Marburg "Untersuchungen zu Proteinsekretion der Blastozyste des Kaninchens
(Oryctolagus cuniculus L.) während der frühen Gravidität" (Investigations on the
protein secretion of rabbit blastocysts during early gravidity)
Examination
Study of Biology and Chemistry for mastership at the Philipps University of
Marburg/Lahn, Germany
Matriculation
Secondary school
Elementary school
Languages:
German: speak, read, write
English: speak, read, write
Afrikaans: read, passive understanding of the language
Prof. Ralf Henkel, PhD
3
Personal Capability Profile of Prof. Dr. rer. nat. Ralf Henkel
1.
Achievements in Research:
1.1. Publications: 242; quotable: 174; first or corresponding authorship: 131
1.2. 68 papers mainly in internationally renowned journals with high impact factor;
32 full papers as first or corresponding author
6 of the original papers have been written upon invitation by internationally renowned
scientists (Prof. Dr. R.G. Edwards, Dr. N. Gleicher, Prof. Dr. A. DeCherney, Prof. Dr.
Oshio)
1.3. 19 book contributions
9 of it upon invitation by Prof. Dr. T.F. Kruger, Prof. Dr. D.R. Franken and
Prof. Dr. Dr. W.-B. Schill
1.4. 201 Abstracts
97 of it quotable
1.5. Presentation of 124 posters at 30 national and 50 international congresses
1.6. Presentation of 144 lectures (including 54 invited lectures) at 24 national and 48
international congresses, and 11 national and 12 international training courses as well as
invited guest lectures
80 of it as first author
1.7. 7 poster prices
2 of it at world congresses
1.8. Successful in raising funds for the yearly research award "Prevention in Andrology –
Endocrinology, Life Style” of the German Society of Andrology donated by the Jenapharm
GmbH & Co. KG (value: € 10,000.--)
1.9. Member of the organization committee of one International Workshop.
Secretary of two International Workshops.
1.10. Member of the Scientific Advisory Board of the Scientific Journal “Andrologia”
1.11. Referee for the National Research Foundation of South Africa
1.12. Member of the Executive Council of the German Society of Andrology (September 2004
until November 2005; resignation because of leaving the Germany and thus not being
available for local council meetings)
1.13. Member of the Editorial Board of the Asian Journal of Andrology
1.14. Member of the Scientific Committee of the 2nd Asia-Pacific Forum on Andrology, 19-23
Oct. 2006
1.15. Elected for Deputy Chair of Department of the Department of Medical Biosciences at the
University of the Western Cape, Bellville, South Africa (Term: January 2006 until
December December 2008)
1.16. Regional Coordinator for Africa for the Asian Journal of Andrology
1.17. Invited to chair several scientific session at several national and international conferences
Prof. Ralf Henkel, PhD
4
1.18. Member of the Scientific Committee of the 3rd Asia-Pacific Forum on Andrology, October
2009
2.
Achievements in the clinic
2.1. Improvement of the andrological diagnosis in the following fields
2.2. Evaluation and establishment of the determination of the acrosome reaction by correlation
in IVF (including the statistics).
Evaluation of the assay has been performed by use of the internationally approved criterion
of fertilization in vitro.
2.3. Optimization, evaluation and establishment of a gelatinolysis method for determination of
acrosin activity in human sperm by correlation in IVF (including the statistics).
Evaluation of the assay has been performed by use of the internationally approved criterion
of fertilization in vitro.
2.4. Evaluation and establishment of the determination of reactive oxygen species (including
the statistics).
2.5. Establishment of the hemizona assay at the Department of Dermatology and Andrology at
the Justus Liebig University of Giessen
2.6. Development of a method to use failed-fertilized oocytes after IVF or ICSI for use in the
hemizona assay
2.7. Optimization of the HOP-Test
2.8. Defining of the oolemma binding of human spermatozoa as separate functional parameter
2.9. Optimization of sperm separation by means of glass wool filtration and Mini-Percoll as
well as the establishment of these methods
2.10. Establishment of disturbed chromatin condensation as criterion for sperm separation by
glass wool filtration
2.11. Establishment of sperm separation methods for the insemination by IUI
2.12. Evaluation of the abnormal stainability of human sperm flagella after Shorr stain with
regard to sperm motility (including the statistics).
2.13. Evaluation of the determination of zinc in human sperm flagella by means of atomic
absorption spectrometry with regard to motility (including the statistics).
2.14. March 1995 till February 1999: Deputy Commissioner for animal protection at the
Department of Dermatology and Andrology, Justus Liebig University of Giessen.
2.15. February 1999 till August 2004: Commissioner for animal protection at the Department of
Dermatology and Andrology.
2.16. Connection of several computers of the Andrological Research Unit to the intra- and the
internet of the university
2.17. Establishment of the production of high-quality slides with the computer; including
training of co-workers
2.18. Establishment of the production of high-quality posters with the computer; including
training of co-workers
Prof. Ralf Henkel, PhD
3.
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Stays in other countries:
2002 – 2004: South Africa
Tygerberg Hospital, Tygerberg
Repeated stays to discuss and to work on the project: Influence of reactive oxygen species
on fragmentation of DNA as a possible cause for pregnancy failure
Prof. Dr. T.F. Kruger, Prof. Dr. D.R. Franken, Dr. R. Menkveld
17.04.01 – 08.05.01: South Africa
Tygerberg Hospital, Tygerberg
Prof. Dr. T.F. Kruger (work on the project: Influence of reactive oxygen species on
fragmentation of DNA as a possible cause for pregnancy failure)
01.01.01-20.01.01: Chile
Department of Obstetrics and Gynaecology, Facultad de Medicina, Universidad de la
Frontera, Temuco
Prof. Dr. R. Sanchez
15.11.99 - 13.12.99: South Africa
Tygerberg Hospital, Tygerberg
Prof. Dr. T.F. Kruger (for special training in IVF and ICSI techniques)
07.08.99 - 16.08.99: South Africa
Tygerberg Hospital, Tygerberg
Prof. Dr. T.F. Kruger (for final writing of the research proposal for the project: Influence of
reactive oxygen species on fragmentation of DNA as a possible cause for pregnancy
failure)
18.03.99 - 09.04.99: South Africa
Tygerberg Hospital, Tygerberg
Prof. Dr. D.R. Franken, Prof. Dr. T.F. Kruger, Dr. R. Menkveld
08.03.98 - 18.04.98: South Africa
Tygerberg Hospital, Tygerberg
Prof. Dr. D.R. Franken, Prof. Dr. T.F. Kruger, Dr. R. Menkveld
13.12.93 - 12.12.94: South Africa
Tygerberg Hospital, Tygerberg
Prof. Dr. D.R. Franken, Prof. Dr. T.F. Kruger, Dr. R. Menkveld
26.09. - 15.10.92: South Africa
Tygerberg Hospital, Tygerberg
Prof. Dr. D.R. Franken, Prof. Dr. T.F. Kruger, Dr. R. Menkveld
29.08. - 23.09.91: Australia
PIVET Medical Center, Perth (2 weeks)
Prof. Dr. J.M. Cummins, Dr. A. Jequier, Dr. J.L. Yovich
Infertility Medical Centre, Monash University, Melbourne (1 week)
Dr. J Osborne
Sydney IVF, Sydney (1 week)
Dr. D. Mortimer
Prof. Ralf Henkel, PhD
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4.
Scientific contacts and cooperations:
Prof. Dr. G. Aumüller, Institute for Anatomy and Cell Biology; Philipps University
Marburg, Germany
Prof. Dr. M.S. Bornman, Department of Urology, University of Pretoria, South Africa
Prof. Dr. J. Cummins, Murdoch University, Perth, Australia
Dr. S. DuPlessis, Department of Medical Physiology, Faculty of Medicine, University of
Stellenbosch, South Africa
Prof. Dr. D.R. Franken, Department of Obstetrics and Gynaecology, Tygerberg Hospital,
Tygerberg, South Africa
Prof. Dr. H.-J. Glander, Department of Dermatology, University of Leipzig, Germany
Dr. U.-C. Hipler, Department of Dermatology, Friedrich Schiller University, Jena,
Germany
Prof. Dr. H. Hutter, Institute for Histology and Embryology, University of Graz, Austria
Dr. C. Huyser, Department of Obstetrics and Gynaecology, University of Pretoria, Pretoria,
South Africa
Prof. Dr. T.F. Kruger, Department of Obstetrics and Gynaecology, Tygerberg Hospital,
Tygerberg, South Africa
Prof. Dr. M. Löffler, Department of Physiological Chemistry, Philipps University,
Marburg, Germany
Prof. Dr. A. Meinhardt, Department of Anatomy and Cell Biology, Justus Liebig
University, Giessen, Germany
Dr. R. Menkveld, Department of Obstetrics and Gynaecology, Tygerberg Hospital,
Tygerberg, South Africa
PD Dr. U. Paasch, Department of Dermatology, University of Leipzig, Germany
Prof. Dr. P. Peña, Universidad de la Fontera, Temuco, Chile
Prof. Dr. R. Sánchez, Universidad de la Fontera, Temuco, Chile
Prof. Dr. Dr. W.-B. Schill, Department of Dermatology and Andrology, Justus Liebig
University, Giessen, Germany
Prof. Dr. G. Schreiber, Department of Dermatology, Friedrich Schiller University, Jena,
Germany
Prof. Dr. H.-C. Schuppe, Department of Dermatology and Andrology, Justus Liebig
University, Giessen, Germany
Dr. I. Schroeder-Printzen, Department of Urology, Justus Liebig University, Giessen,
Germany
Dr. Th. Stalf, IVF-Center at the Department of Obstetrics and Gynaecology, Justus Liebig
University, Giessen, Germany
Prof. Dr. H.-R. Tinneberg, Department of Obstetrics and Gynaecology, Justus Liebig
University, Giessen, Germany
Prof. Dr. T. Trenczeck, Department of Biology, Justus Liebig University, Giessen,
Germany
Prof. Dr. J. Villegas Moraga, Universidad de la Fontera, Temuco, Chile
Prof. Dr. W. Weidner, Department of Urology, Justus Liebig University, Giessen, Germany
5.
Memberships in scientific societies:
German Society for Andrology (September 2004 until November 2005: Member of the
Executive Council)
Prof. Ralf Henkel, PhD
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6.
Referee for research funding organizations
National Research Foundation of South Africa
7.
Expert for the following scientific journals:
 Asian Journal of Andrology (Member of the Editorial Board; Regional Coordinator for
Africa)
 Andrologia (Member of the Scientific Advisory Board)
 Human Reproduction
 Molecular Human Reproduction
 Fertility and Sterility
 Reproductive Biomedicine Online
 International Journal of Andrology
 Journal of Andrology
 Gynecological Endocrinology
 Journal of Reproduction and Fertility
 Cell and Tissue Research
 Canadian Medical Association Journal
 World Journal of Urology
 Reproduction in Domestic Animals
 Central European Journal of Medicine
8.
Evaluated and financially supported scientific projects (Total amount of money: more
than € 1.2 Mill. ≈ USD 1.4 Mill.):
Jan. 2007 – Dec. 2011
Principal investigator and project leader of the South African National Research
Foundation funded project: “The effect of South African indigenous medicinal
herbs and their extracts on male reproductive functions”
Apr. 2002 – Dec. 2003
Principal investigator and project leader of the collaborative project with the
Schering AG „Reduction of the zona binding of human spermatozoa by means of
sperm surface proteins or antibodies against these surface proteins”
Mar. 2001 - Sep. 2005
Principal investigator and project leader of the cooperative project with the
University of Stellenbosch (Prof. TF Kruger, Dr. R Menkveld) sponsored by the
Volkswagen Foundation and the University of Stellenbosch, Stellenbosch, South
Africa. „Influence of reactive oxygen species on fragmentation of DNA as a
possible cause for pregnancy failure“
Aug. 2000 - Apr. 2001
Project leader of the project sponsored by the Schering AG "Development of a new
chemiluminescence enhanced zona binding assay"
Jan. 2000 - Dec. 2000
Co-Project leader of the project sponsored by Ferring GmbH “Fertilizing ability of
spermatozoa by considering seasonal changes of ejaculate quality and sperm
functions”
Jan. 2000 - Dec. 2000
Co-Project leader of the project sponsored by Ferring GmbH “Effect of
inflammatory parameters and reactive oxygen species on sperm motility”
Prof. Ralf Henkel, PhD
8
Jan. 2000 - Dec. 2003
German head of the collaborative project with Prof. Kruger "Influence of reactive
oxygen species on fragmentation of DNA as a possible cause for pregnancy failure"
(approved by the University of Stellenbosch, South Africa)
Dec. 1999 till Aug. 2000
Principal investigator and project leader of the project sponsored by the Schering
AG "Development of a new chemiluminescence enhanced zona binding assay"
Oct. 1999 - Oct. 2002
Principal investigator and project leader of the project "Involvement of the
epididymis in the elimination of zinc from spermatozoa during epididymal transit"
within the scope of the DFG-Graduate-College "Cell-cell-interaction in
reproduction"
Aug. 1999 - Aug. 2000
Principal investigator and project leader of the clinical study sponsored by Hexal
AG: ”Reduction of reactive oxygen species in human seminal plasma”
June 1999 - June 2001
Principal investigator and project leader of the DFG-project; "Elimination of the
element zinc from spermatozoa during epididymal transit"
Mar. 1999 – Mar. 2002
Principal investigator and project leader of a project sponsored by the ScheringResearch Foundation; ”Biomechanics and bioenergetics of flagella as basis for the
development of a non-hormonal contraception”
Oct. 1997 – Mar. 1998
Pilot study sponsored by Hexal AG: ”Reduction of reactive oxygen species in
human seminal plasma”
Apr. 1997 – Apr. 1999
A flowcytometer has been placed to my disposal for the development of new test
systems in Andrology by Coulter-Immunotech
July 1996 - July 1998
Co-Project leader of the DFG-project; ”Proteinbiochemical and immunological
characterization and investigations of the physiology of the outer dense fibres of
human spermatozoa.”
Mar. 1995 – Mar. 1996
Scholar from Okayama Hospital, Okayama, Japan, for the project "Reduction of
reactive oxygen species in the human ejaculate by means of anti-oxidants’
Mar. 1994 – Mar. 1995
Scholar from Okayama Hospital, Okayama, Japan, for the project "The importance
of reactive oxygen species (ROS) for several functional sperm parameters"
(financed by Okayama University)
Dec. 1993 - Dec. 1994
Scholarship of the "Stifterverbandes für die Deutsche Wissenschaft" for the project:
"Acrosome reaction of human spermatozoa: Standardization of existing laboratory
protocols for the evaluation of the acrosome reaction and investigation of the
influence of human zona pellucida on the acrosome reaction.", Department of
Obstetrics and Gynaecology, Reproductive Biology Unit, Tygerberg Hospital,
Tygerberg, South Africa, Prof. D.R. Franken and Prof. T.F. Kruger
Oct. 1993 - Jan. 1996
Principal investigator and project leader of the DFG-project; "Sperm-oolemmaInteraction"
Prof. Ralf Henkel, PhD
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June 1993 - June 1995
Co-project leader of the DFG-project; "Proteinchemical characterization and
investigations of the physiology of human sperm outer dense fibres"
May 1992 - May 1995
Principal investigator and project leader of the project by the Federal Ministry of
Research and Technology; ‘Binding and species specific recognition in sperm-egginteraction’ in the research co-operative ‘Physiology and Pathology of
Fertilization’.
9.
Supervised scientific theses:
Scientific theses for the teaching profession in Biology:
Christian Heindl; Department of Biology, Philipps University Marburg; Thesis title:
Strukturelle und funktionelle Grundlagen der Spermienbeweglichkeit; (very good)
(1995)
Martin Sieber; Department of Biology, Philipps University Marburg; Thesis title: Neuere
Aspekte zu Ursachen und Therapiemöglichkeiten der Infertilität des Mannes; (very
good) (1996)
Honours theses in Medical Biosciences:
Finished theses:
Warren Fransman; Department of Medical Biosciences, University of the Western Cape;
Thesis title: In vitro effects of Typha capensis extracts on sperm motility and
mitochondrial membrane potential; (cum laude) (2007)
Nicolette Erasmus; Department of Medical Biosciences, University of the Western Cape;
Thesis title: The effects of Typha capensis extracts on acrosome reaction of human
spermatozoa. (2007)
Nicole Haines; Department of Medical Biosciences, University of the Western Cape;
Thesis title: The effect of aqueous Typha capensis extract on TM4-Sertoli cell
function. (2008)
Michael Berry; Department of Medical Biosciences, University of the Western Cape;
Thesis title: In vitro Effects of Hermannia ciliaris and Cissampelos capensis on
human sperm function (2008)
Eurinah Harris; Department of Medical Biosciences, University of the Western Cape; (cosupervision with Dr. D. Fisher); Thesis title: The effect of transepithlial electrical
resistance on the tight junctions of TM4 Sertoli cells using a herbal extract: Typha
capensis (2008)
Current and experimentally finished theses:
Festers, Jonade; Department of Medical Biosciences, University of the Western Cape;
Thesis title:
Jacobs, Delano; Department of Medical Biosciences, University of the Western Cape;
Thesis title:
Zuma, Jabulisile; Department of Medical Biosciences, University of the Western Cape;
Thesis title:
Prof. Ralf Henkel, PhD
10
Masters theses in Biology:
Finished theses:
Thomas Stalf; Department of Biology, Justus Liebig University Giessen; Thesis title:
Isolierung und biochemische Charakterisierung der Mantelfasern aus humanen
Spermatozoen; (very good) (1992)
Petra Baltes; Department of Biology, Justus Liebig University Giessen; Thesis title:
Charakterisierung und Anreicherung einer die Akrosomreaktion bei humanen
Spermatozoen induzierenden Substanz (ARIS) aus menschlicher
Follikularflüssigkeit; (very good) (1993)
Kerstin Defosse; Department of Biology, Justus Liebig University Giessen; Thesis title:
Energieverbrauch, Leistung und Zinkkonzentration humaner Spermatozoen unter
desonderer Berücksichtigung der Motilität; (very good) (2000)
Ursula Teichmann; Department of Biology, Justus Liebig University Giessen; Thesis title:
Einfluß verschiedener Metallkationen auf die Akrosomreaktion und die Motilität
menschlicher Spermatozoen; (very good) (2000)
Piotr Kos; Department of Biology, Justus Liebig University Giessen; Thesis title:
Charakterisierung proteolytischer Aktivitäten von peritubulären Zellen des
Rattentestes mittels HPLC-Analyse am Beispiel des Bradykininabbaus; (very good)
(2001)
Eva Kierspel; Department of Biology, Justus Liebig University Giessen; Thesis title: Der
Einfluss von reaktiven Sauerstoffspezies auf die DNA-Fragmentation in humanen
Spermatozoen und deren mögliche Auswirkung auf die Schwangerschaft; (good)
(2003)
Rolf Schäfer; Department of Biology, Justus Liebig University Giessen; Thesis title: Die
Bedeutung von Zink im Flagellum humaner Spermatozoen für die Motilität; (very
good) (2003)
Stephanie Butendeich; Department of Biology, Justus Liebig University Giessen; Thesis
title: Expression der mRNA des Bradykinin-B2-Rezeptors im Reproduktionstrakt der
männlichen Ratte; (good) (2003)
Current and experimentally finished theses:
Warren Fransman; Department of Medical Biosciences, University of the Western Cape;
Thesis title: In vivo effects of Typha capensis extracts on sperm function in the rat.
Nicolette Erasmus; Department of Medical Biosciences, University of the Western Cape;
Thesis title: Investigations on the in vivo effects of aqueous extracts of Typha
capensis on male reproductive functions in the rat.
Cleyson Mupfiga; Department of Medical Biosciences, University of the Western Cape;
Thesis title: Relationship between male genital tract infection, oxidative status in the
ejaculate, and mitochondrial and nuclear DNA damage in human sperm.
Nicole Haines; Department of Medical Biosciences, University of the Western Cape;
Thesis title:
Doctoral theses in natural science:
Finished theses:
Dr. rer. nat. Thomas Stalf; Department of Biology, Justus Liebig University Giessen;
Thesis title: Isolierung, Charakterisierung und partielle Sequenzanalyse der
Mantelfaserproteine aus Säugerspermatozoen; (magna cum laude) (1995)
Dr. rer. nat. Petra Baltes; Department of Biology, Justus Liebig University Giessen; Thesis
title: Molekulare Grundlagen der Induktion der Akrosomreaktion durch menschliche
Follikelflüssigkeit; (magna cum laude) (1996)
Prof. Ralf Henkel, PhD
11
Dr. rer. nat. Christa Finkenzeller; Department of Pharmacy, Ludwig Maximilians
University Munich; (very good) (1997)
Dr. rer. nat. Uwe Schalles; Department of Biology, Philipps University Marburg; Thesis
title: Charakterisierung unf Indentifizierung von Mantelfaserproteinen aus
Spermatozoen verschiedener Säugetiere; (very good) (1998)
Dr. rer. nat. Sonja Blöcher; Department of Biology, Justus Liebig University Giessen;
Thesis title: Altersabhängige Expression der Serinprotease Gewebs-Kallikrein und
des Bradykinin-B2-Rezeptors im Hoden der Ratte; (magna cum laude) (2001)
Dr. rer. nat. Brigitte Seefeldt-Schmidt; Department of Biology, Justus Liebig University
Giessen; Thesis title: Proteinchemische und immunologische Charakterisierung
zweier niedermolekularer Mantelfaser-Proteine aus bovinen Spermatozoen; (magna
cum laude) (2003)
Dr. rer. nat. Christina Baldauf; Department of Biology, University of Kassel; Thesis title:
Untersuchungen zur Eliminierung und Resorption von Zink aus Säugerspermatozoen
während der Nebenhodenpassage; (very good) (2003)
Christiaan Hoogendijk,PhD, Department of Obstetrics and Gynaecology, University of
Stellenbosch, Stellenbosch, South Africa; Thesis title: Sperm DNA fragmentation:
Implications in assisted reproductive technologies; (2007)
Current and experimentally finished theses:
Liana Maree, MSc; Department of Medical Biosciences, University of the Western Cape;
(co-supervision with Prof. van der Horst); Thesis title: Sperm mitochondria: Species
specificity and relationships to sperm morphometric features, function and sperm
quality in selected mammalian species;
Andries Burger, MSc; Department of Medical Biosciences, University of the Western
Cape; Thesis title: The cardiovascular effects of Crinum macowanii in the Wistar rat.
Doctoral theses in medicine:
Finished theses:
Dr. med. Jörg Bittner; Justus Liebig University Giessen; Thesis title: Die Bedeutung von
Zink in menschlichen Spermatozoen und seine Beziehung zur Motilität und
Morphologie; (summa cum laude) (1997)
Dr. med. Christina Müller; Justus Liebig University Giessen; Thesis title: Klinische
Relevanz unterschiedlicher Spermatozoenparameter für die Fertilisation in vitro;
(magna cum laude) (1998)
Dr. med. Volker Maier; Justus Liebig University Giessen; Thesis title: Ultrastrukturelle
Untersuchungen an bovinen Mantelfasern; (magna cum laude) (2000)
Dr. med. Philipp Schneider; Justus Liebig University Giessen; Thesis title: Intrazelluläre
Signaltransduktion bei der Akrosomreaktion und ihre Bedeutung für die Fertilisation;
(summa cum laude) (2000)
Dr. med. Nico Wroblewski; Justus Liebig University Giessen; Thesis title: Beeinflussung
der Motilität humaner Spermatozoen mittels verschiedener Chelatbildner in vitro;
(magna cum laude) (2001)
Dr. med.dent. Swantje Gebhardt; Justus Liebig University Giessen; Thesis title: Einfluß
von Metallionen auf ausgewählte Funktionsparameter von Sertoli-Zellen –
Potentielles Testsystem zur Prüfung männlicher Fertilitätsstörungen; (magna cum
laude) (2004)
Dr. med. Maryam Börner, geb. Hajimohammad; Justus Liebig University Giessen; Thesis
title: Die Bedeutung von Apoptose und Spermien DNA-Fragmentation für
Fertilisation und Schwangerschaft; (cum laude) (2004)
Prof. Ralf Henkel, PhD
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Dr. med. Matthias Franz; Justus Liebig University Giessen; Thesis title: Entwicklung und
Evaluierung eines in-vitro-Testsystems zur Überprüfung der Wirkung von
Organochlorpestiziden auf Sertolizellen der Ratte; (cum laude) (2004)
Dr. med. Sonja Hinkel; Justus Liebig University Giessen; Thesis title: Der Einfluß von
Estrogenen und Xenoestrogenen auf die Testosteron-, Progesteron- und
Laktatproduktion sowie die Vitalität der R2C Leydig-Zellen von Ratten; (cum laude)
(2006)
Dr. med. Kathrin Bittorf; Justus Liebig University Giessen; Thesis title: Wirkung von
Substanzen mit östrogener Wirkung und synthetischen Nitromoschusduftstoffen auf
ausgewählte Funktionsparameter von Sertoli-Zellen der Ratte. Entwicklung und
Evaluierung eines in vitro-Testsystems; (cum laude) (2006)
Dr. med. Catia Loddo; Justus Liebig University Giessen; Thesis title:
Immunhistochemische Detektion von Komponenten des Kallikrein-Kinin-Systems in
Testis und Epididymis verschiedener Spezies; (magna cum laude) (2007)
Dr. med. Anne Sturmhoefel, Friedrich Schiller University Jena; Thesis title: Einfluß
verschiedener Entzündungen des männlichen Genitalsystems auf die Funktionalität
menschlicher Spermatozoen; (cum laude) (2007)
Dr. med. Gesa Maaß; Justus Liebig University Giessen; Thesis title: Zusammenhang
funktioneller Spermatozoenparameter; (2008)
Current and experimentally finished theses:
Sabine Schüller, Friedrich Schiller University Jena; Thesis title: Zusammenhang zwischen
der Spermien-Chromatinkondensation und endogener DNA-Fragmentation sowie
deren Einfluß auf Fertilisation und Schwangerschaft im IVF-Programm;
Post-doctoral studies supervised:
Dr. Takaharu Ichikawa; Okayama University, Okayama, Japan (1994-1995)
Dr. Tadashi Oeda; Okayama University, Okayama, Japan (1995-1996)
Dr. Hadley Bastiaan; University of the Western Cape, (co-supervision with Dr. D. Fisher);
Bellville, South Africa (2007-current)
Dr. Johan Mars; University of the Western Cape, Bellville, South Africa (2008-current)
10.
Internal and External Examination of Theses
 Internal Examination MSc
o Charon de Villiers, University of the Western Cape, Bellville, South Africa,
Thesis title: The effect of gonadotropin-releasing hormones (GNRH) I & II on
sperm motility and acrosome status of the Vervet Monkey (Chlorocebus
aethiops) in vitro; (2006)
o Linda Sissing, University of the Western Cape, Bellville, South Africa, Thesis
title: Investigations into the cancer modulating properties of Aspalathus linearis
(Rooibos), Cyclopia intermedia (Honeybush) and Sutherlandia frutescens
(Cancer bush) in oesophagaeal carcinogenesis; (2007)

Internal Examination PhD
o Nicole Brooks, University of the Western Cape, Bellville, South Africa, Thesis
title: Apoptotic markers in ejaculated human spermatozoa; (2006)
Prof. Ralf Henkel, PhD

13
External Examination PhD
o Christiaan Hoogendijk, University of Stellenbosch, Stellenbosch, South Africa,
Sperm DNA fragmentation: Implications in assisted reproductive technologies;
(2007)
o Namita Samanta, Guru Gobind Singh Indraprastha University, Dehli, India,
Thesis title: Studies on radiomodifying effects of some herbal preparations on
stem cells and associated tissues in mice testis; (2007)
11.
Commissional work at the Department, Faculty and University
 Member of the Selection Commission for medical students at the Faculty of Medicine,
Justus Liebig University, Giessen (2000-2004)
 Chair of the Departmental Post-graduate Committee (Department of Medical
Biosciences at UWC; since October 2005)
 Member of Senate of the University of the Western Cape (since January 2006)
 Chair of the Departmental Research Committee (Department of Medical Biosciences at
UWC; since November 2005)
 Member of the Departmental Planning Committee (Department of Medical Biosciences
at UWC; since November 2005)
 Member of the Faculty Post-graduate Committee (Faculty of Natural Sciences at UWC;
since October 2005)
 Member of the Faculty Academic Planning Committee (Faculty of Natural Sciences at
UWC; January 2006 till December 2007)
 Member of the Faculty Appointments Committee (Faculty of Natural Sciences at
UWC; since January 2007)
 Member of the Annual Academic Personal Promotions Committee (Faculty of Natural
Sciences at UWC; since January 2007)
 Faculty representative of the Faculty Higher Degrees Committee for the HEQC
Institutional Audit of the University of the Western Cape, Bellville, South Africa; 2007
 Member of the Search Committee for an Associate Professor/Professor in Sport,
Recreation and Exercise Science at UWC; 2008/2009
12.
Teaching
 Lecture: “Reproductive Biology of the Man” at the Medical Faculty, Justus Liebig
University Giessen and at the Medical Faculty, Friedrich Schiller University Jena
 Contribution to the ring lecture ‘Reproductive Medicine’ at the Medical Faculty, Justus
Liebig University Giessen
 Course ”Exercises in Reproductive Biology” at the Department of Biology, Faculty of
Science, Justus Liebig University Giessen
 Contribution to the course “Anthropology” at the Department of Biology, Faculty of
Science, Justus Liebig University Giessen
 “Project courses in Reproductive Biology” at the Department of Biology, Faculty of
Science, Justus Liebig University Giessen
 Supervision of 8 masters degrees in Biology, 9 natural scientific and 14 medical
doctoral degrees
 Organization of 3 training courses ”Sperm separation” for gynaecologists at the Medical
Faculty, Justus Liebig University Giessen
 Seminar for doctoral students in andrology at the Medical Faculty, Justus Liebig
University Giessen and at the Medical Faculty, Friedrich Schiller University Jena
Prof. Ralf Henkel, PhD
14
 Reproductive biology colloquium at the Department of Dermatology and Andrology,
Justus Liebig University Giessen
 Contribution to lecture “Innovations in Urology” at the Medical Faculty, Friedrich
Schiller University Jena
 Course ”Andrology” at the Department of Urology, Friedrich Schiller University, Jena
 Part of lectures and practicals for “Human Biology for BChD I” (HUB 105) (The
Respiratory System; The Renal System)
 Part of lectures and practicals for “Research Methodology I and II” (MBS 315, MBS
325) for 3rd year students in Medical Bioscience
 Part of lectures and practicals for “Applied Reproduction” (MBS 312) for 3rd year
students in Medical Bioscience
 Part of lectures and practicals for “Advanced Studies in Reproduction and Health”
(MBS 713) for Honours students in Medical Bioscience
 Part of lectures and practicals for “Introduction to the Human Body II” (MBS 121) for
first year students in Medical Bioscience
 Part of lectures and practicals for “Homeostatic Systems” (MBS 222) for second year in
Medical Bioscience
Prof. Ralf Henkel, PhD
15
List of publications
Prof. Dr. rer. nat. Ralf Henkel
Original papers:
1.
Dannhorn,DR, Henkel,R und Kirchner,C (1988)
Synthese von Uteroglobin in der Blastozyste des Kaninchens? Autoradiographische und
immunocytochemische Untersuchungen.
Fertilität 4, 223-226
2.
Wirth,B, Dannhorn,D, Henkel,R und Kirchner,C (1989)
Einfluß des Antigestagens ZK 98.299 auf den Kaninchenuterus in der
Präimplantationsphase.
Fertilität 5, 184-187
3.
Henkel,R, Dannhorn,DR, Petzoldt,U and Kirchner,C (1990)
Ultrastructure, protein synthesis and secretion of day-6 rabbit blastocysts in a chemically
defined, protein-free medium.
Anat Embryol 182, 465-472
4.
Haidl,G, Becker,A and Henkel,R (1991)
Poor development of outer dense fibers as a major cause of tail abnormalities in the
spermatozoa of asthenoteratozoospermic men.
Hum Reprod 6: 1431-1438
5.
Henkel,R, Müller,C, Miska,W, Schill,W-B und Gips,H (1992)
Die Bestimmung der akrosomalen Reaktion in der andrologischen Diagnostik und ihre
Bedeutung für die IVF. Eine vorläufige Analyse.
Fertilität 8: 27-30
6.
Henkel,R, Stalf,T and Miska,W (1992)
Isolation and partial characterization of the outer dense fiber proteins from human
spermatozoa.
Biol Chem Hoppe-Seyler Vol. 373: 685-689
7.
Henkel,R, Müller,C, Miska,W, Gips,H and Schill,W-B (1993)
Determination of the acrosome reaction of human spermatozoa is predictive of fertilization
in vitro.
Hum Reprod 8: 2128-2132
8.
Köhn,F-M, Henkel,R und Schill,W-B (1993)
Pentoxifyllin stimuliert die Motilität von Spermatozoen nach Kryokonservierung.
Fertilität 9: 79-84
9.
Stalf,T, Henkel,R und Miska,W (1993)
Weitere Untersuchungen zur Proteinzusammensetzung der Mantelfasern in menschlichen
Spermatozoen.
Fertilität 9: 203-209
10.
Henkel,R, Stalf,T, Mertens,N, Miska,W and Schill,W-B (1994)
Outer dense fibers of human spermatozoa. -Partial characterization and possible
physiological functions-.
Int J Androl 17: 68-73
Prof. Ralf Henkel, PhD
16
11.
Miska,W, Fehl,P and Henkel,R (1994)
Biochemical and immunological characterization of the acrosome reaction-inducing
substance of human follicular fluid.
Biochem Biophys Res Commun 199: 125-129
12.
Henkel,R, Müller,C, Miska,W, Gips,H and Schill,W-B (1994)
Determination of the acrosome reaction in human spermatozoa is predictive for
fertilization in vitro.
Fertility Digest 5: 10-13
13.
Henkel,R, Franken,DR, Lombard,CJ and Schill,W-B (1994)
The selective capacity of glass wool filtration for normal chromatin condensed human
spermatozoa: A possible therapeutic modality for male factor cases?
J Assist Reprod Genet 11: 395-400
14.
Miska,W, Henkel,R and Fehl,P (1994)
Structure/molecular mass of the acrosome reaction-inducing substance (ARIS) in human
follicular fluid.
Mol Androl 6: 133-145
15.
Henkel,R, Müller,C, Miska,W, Schill,W-B, Kleinstein,J and Gips,H (1995)
Determination of the acrosin activity of human spermatozoa by means of a gelatinolytic
technique. A simple, predictive method useful for IVF.
J Androl 16: 272-277
16.
Fehl,P, Miska,W and Henkel,R (1995)
Further indications of the multicomponent nature of the acrosome reaction-inducing
substance of human follicular fluid.
Mol Reprod Dev 42: 80-88
17.
Henkel,R, Cooper,S, Kaskar, K, Schill,W-B, Habenicht,U-F and Franken,DR (1995)
Influence of elevated pH levels on structural and functional characteristics of the human
zona pellucida: Functional morphological aspects.
J Assisted Reprod Genet 12: 644-649
18.
Franken,DR, Henkel,R, Kaskar,K and Habenicht,U-F (1996)
Defining bioassay conditions to evaluate sperm/zona interaction: Inhibition of zona binding
mediated by solubilized human zona pellucida.
J Assisted Reprod Genet 13: 329-332
19.
Sanchez Sarmiento,CA, Coetzee,K, Kruger,TF, van der Merwe,JP, Stander,FSH,
Henkel,RR and Lombard,C (1996)
Comparison between swim-up and glass wool column filtration of human semen in a
gamete intrafallopian transfer program.
Arch Androl 36: 155-160
20.
Sánchez,R, Concha,M, Ichikawa,T, Henkel,R and Schill,W-B (1996)
Glass wool filtration reduces reactive oxygen species by elimination of leukocytes in
oligozoospermic patients with leukocytospermia.
J Assisted Reprod Genet 13: 489-494
21.
Henkel,R, Schaller,J, Glander,H-J and Schill,W-B (1996)
Low expression of adhesion molecules and matrix proteins in patients showing poor
penetration in zona-free hamster oocytes
Mol Hum Reprod 2: 335-339
Prof. Ralf Henkel, PhD
17
22.
Hutter,H, Hammer,A, Blaschitz,A, Hartmann,M, Mahnert,W, Sedlmayr,P, Primus,G,
Rosenkranz,C, Gebru,G, Henkel,R and Dohr,G (1996)
The monoclonal antibody GZS-1 detects a maturation-associated antigen of human
spermatozoa that is also present on the surface of human mononuclear blood cells.
J Reprod Immunol 30: 115-132
23.
Oeda,T, Henkel,R, Ohmori,H and Schill,W-B (1997)
Scavenging effect of N-acetyl-L-cysteine against reactive oxygen species in human semen:
A possible therapy in male factor infertility?
Andrologia 29: 125-131
24.
Henkel,R, Ichikawa,T, Sánchez,R, Miska,W, Ohmori,H and Schill,W-B (1997)
Differentiation of ejaculates in which reactive oxygen species are generated by
spermatozoa or leukocytes.
Andrologia 29: 295-301
25.
Henkel,R, Kleinhappl,M, Hanschke,A und Schill,W-B (1998)
Jahreszeitliche Schwankungen der Ejakulatqualität.
Fertilität 14: S37-S41
26.
Henkel,R, Müller,C and Miska,W (1998)
Induction of acrosome reaction by low temperature is comparable to physiological
induction by human follicular fluid.
Andrologia 30: 159-161
27.
Glander,H-J, Schaller,J, Rohwedder,A and Henkel,R (1998)
Adhesion molecules and matrix proteins on human spermatozoa.
Andrologia 30: 289-296
28.
Henkel,R, Franken,DR and Habenicht,U-F (1998)
Zona pellucida as physiological trigger for the induction of acrosome reaction.
Andrologia 30: 275-280
29.
Köhn,FM, Müller,C, Drescher,D, Neukamm,C, El Mulla,KF, Henkel,R, Habenicht,U-F
and Schill W-B (1998)
Effect of angiotensin converting enzyme (ACE) and angiotensins on human sperm
functions.
Andrologia 30: 207-215
30.
Villegas,J, Henkel,R, Folch,H, Sanchez,R, Schill,W-B and Miska,W (1998)
Production and characterization of monoclonal antibodies to the major protein of boar
outer dense fibres.
J Reprod Immunol 40: 81-91
31.
Henkel,R, Müller,C, Stalf,T, Schill,W-B and Franken,DR (1999)
Use of failed-fertilized oocytes for diagnostic zona binding purfoses after sperm binding
improvement with a modified medium.
J Assisted Reprod Genet 16: 24-29
32.
Stalf,T, Herrero,J, Turley,H, Hinz,V, Müller,B, Blank,T, Henkel,R, Schill,W-B and Gips,H
(1999)
Different cumulative pregnancy rates of patients with repeated IVF- or ICSI-treated cycles:
Possible influence of a male factor.
Andrologia 31: 149-156
Prof. Ralf Henkel, PhD
18
33.
Henkel,R, Bittner,J, Weber,R, Hüther,F and Miska,W (1999)
Relevance of zinc in human sperm flagella and its relation to motility.
Fertil Steril 71: 1138-1143
34.
Glander,H-J, Schaller,J, Rohwedder,A and Henkel,R (1999)
Spermien-Adhäsionsmoleküle (AM) sind mögliche Mediatoren der Spermien-OozytenInteraktion.
Reproduktionsmedizin 15: 231-239
35.
Henkel,R und Schill,W-B (2000)
Die Bedeutung funktioneller Spermatozoenparameter für den Fertilisationsprozeß.
Reproduktionsmedizin 16: 81-89
36.
Sánchez,R, Peña,P, Miska,W and Henkel,R (2000)
Determination de la variabilidad en la condensación de la cromatina espermatica y
-glucosidasa seminal en relación al espermiograma.
Rev. Med. Chil. 128: 483-489
37.
Henkel,R, Baldauf,Ch, Bittner,J, Weidner,W and Miska,W (2001)
Elimination of zinc from the flagella of spermatozoa during epididymal transit is important
for motility.
Reprod Technol 10: 280-285
38.
Henkel,R, Finkenzeller,C, Monsees,T, Franken,DR, Schill,W-B and Miska,W (2001)
Development and evaluation of a new, highly sensitive zona pellucida binding assay using
a bioluminescence-enhanced detection system.
Andrologia 33: 215-221
39.
Henkel,R, Menkveld,R, Kleinhappl,M and Schill,W-B (2001)
Seasonal changes of human sperm chromatin condensation.
J Assisted Reprod Genet 18: 371-377
40.
Villegas,J, Schulz,M, Vallejos,V, Henkel,R, Miska,W and Sánchez,R (2002)
Indirect immunofluorescence using monoclonal antibodies for the detection of
leukocytospermia: Comparison with the peroxidase staining.
Andrologia 34: 69-73
41.
Henkel,R, Defosse,K, Koyro,H-W, Weißmann,N and Schill,W-B (2003)
Estimate of the oxygen consumption and intracellular zinc concentration of human
spermatozoa in relation to motility.
Asian J Androl 5: 3-8
42.
Henkel,R, Baldauf,Ch and Schill,W-B (2003)
Resorption of the element zinc from spermatozoa by the epididymal epithelium.
Reprod Dom Anim 38: 97-101
43.
Wroblewski,N, Schill,W-B and Henkel,R (2003)
Metal chelators change the human sperm motility pattern.
Fertil Steril 79 S3: 1584-1589
44.
Villegas,J, Kehr,K, Soto,L, Henkel,R, Miska,W and Sánchez,R (2003)
Reactive oxygen species induce reversible capacitation in human spermatozoa.
Andrologia 35: 227-232
Prof. Ralf Henkel, PhD
19
45.
Henkel,R, Kierspel,E, Hajimohammad,M, Stalf,T, Hoogendijk,C, Mehnert,C, Menkveld,R,
Schill,W-B and Kruger,TF (2003)
DNA fragmentation of spermatozoa and ART.
Reprod Biomed Online 7: 477-484
46.
Menkveld,R, El-Garem,Y, Schill,W-B and Henkel,R (2003)
Relationship between acrosomal function and sperm morphology.
J Assisted Reprod Genet 20: 432-438
47.
Henkel,R, Hajimohammad,M, Stalf,T, Mehnert,C, Menkveld,R, Gips,H, Schill,W-B and
Kruger,TF (2004)
Influence of DNA damage on fertilization and pregnancy.
Fertil Steril 81: 965-972
48.
Schill,W-B and Henkel,R (2004)
Sperm function and outcome of assisted reproduction.
Proceedings of the 1st World Congress & Workshop on Assisted Fertilization, Conception
and Molecular Reproduction, p69-72
49.
Eickhoff,R, Baldauf,C, Koyro,H-W, Wennemuth,G, Suga,Y, Seitz,J, Henkel,R and
Meinhardt,A (2004)
Influence of macrophage migration inhibitory factor (MIF) on the zinc content and redox
state of protein bound sulfhydryl groups in rat spermatozoa. Indications for a new role of
MIF in sperm maturation.
Mol Hum Reprod 10: 605-611
50.
Henkel,R, Kierspel,E, Stalf,T, Mehnert,C, Tinneberg,H-R, Menkveld,R, Schill,W-B and
Kruger,TF (2005)
Effect of reactive oxygen species produced by spermatozoa and leukocytes on sperm
functions in non-leukocytospermic patients.
Fertil Steril 83: 635-642
51.
Henkel,R, Maaß,G, Schuppe,H-C, Jung,A, Schubert,J and Schill,W-B (2005)
Molecular aspects of declining sperm motility in older men.
Fertil Steril 84: 1430-1437
52.
Henkel,R, Maaß,G, Schuppe,H-C, Jung,A and Schill,W-B (2006)
Seasonal changes of α-glucosidase activity in human semen.
J Androl 27: 34-39
53.
Henkel,R, Ludwig,M, Schuppe,H-C, Diemer,T, Schill,W-B and Weidner,W (2006)
Chronic pelvic pain syndrome and prostatitis affect the acrosome reaction in human
spermatozoa.
World J Urol 24: 39-44
54.
Niemeyer,T, Dietz,C, Fairbanks,L, Schroeder-Printzen,I, Henkel,R, Löffler,M (2006)
Evaluation of uridine metabolism in human and animal spermatozoa.
Nucleosides, Nucleotides and Nucleic Acids 25: 1215-1219
55.
Hoogendijk,CF, Kruger,TF, de Beer,M-L, Siebert,TI and Henkel,R (2007)
A study of two sequential media: The impact on embryo quality and pregnancy rates.
S Afr J Obstet Gynaecol 13: 52-58
Prof. Ralf Henkel, PhD
20
56.
Henkel,R, Maaß,G, Schuppe,H-C, Jung,A, Haidl,G and Schill,W-B (2007)
Age-related changes in seminal polymorphonuclear elastase in patients with silent male
genital tract infection.
Asian J Androl 9: 299-304
57.
Henkel,R, Schreiber,G, Sturmhoefel,A, Hipler,UC, Zermann,DH and Menkveld,R (2008)
Comparison of three staining methods for the morphological evaluation of human
spermatozoa.
Fertil Steril 89: 449-455
58.
Hoogendijk,CF, Kruger,TF, Bouic,PJD and Henkel,R (2008)
A novel approach for the selection human sperm using annexin V-binding and flow
cytometry.
Fertil Steril; Mar 25; [Epub ahead of print]
59.
Henkel,R, Hoogendijk,CF, Bouic,PJD, Kruger,TF (2009)
TUNEL assay and SCSA® determine different aspects of sperm DNA damage.
Fertil Steril (submitted)
60.
Hoogendijk,CF, Kruger,TF, Bouic,PJD and Henkel R (2009)
P-pattern sperm morphology and DNA fragmentation.
Fertil Steril (submitted)
61.
Henkel,R, Bastiaan,HS, Schüller,S, Hoppe,I, Starker,W and Menkveld,R (2009)
Oxidative stress may be a factor compromising sperm chromatin condensation status.
Andrologia (submitted)
62.
Fransman,WO, Menkveld,R, Weitz,F, Kruger,TF, Fisher,D, Henkel,R (2009)
In vitro effects of Typha capensis extracts on sperm motility and mitochondrial membrane
potential.
Asian J Androl (in preparation)
63.
Mehnert,C, Stalf,T, Tinneberg,H-R, Schill,W-B and Henkel,R (2009)
Establishment of a protein-free primary culture of bovine epithelial cells and the impact of
the element zinc.
Theriogenology (in preparation)
64.
Hayek-Ouassini,M, Fairbanks,LD, Henkel,R, Simmonds,AH, Rudnik,J and Löffler,M
(2009)
Uridine and orotate in human seminal plasma of fertile, infertile and vasectomized men.
Reproduction (in preparation)
65.
Monsees,TK, Kos,P, Henkel,R, Schill,W-B (2009)
Bradykinin-degrading proteases in peritubular cells of the rat testis.
(in preparation)
66.
Henkel,R, Sturmhoefel,A, Menkveld,R, Hipler,UC, Zermann,DH and Schreiber,G (2009)
Influence of the localization of a male genital tract infection on the functionality of human
spermatozoa.
(in preparation)
Prof. Ralf Henkel, PhD
Overviews:
1.
Schill,W-B, Henkel,R, Miska,W, Kleinstein,J und Gips,H (1993)
Zur Bedeutung der Spermatozoenfunktionsdiagnostik für das IVF-Programm.
Fertilität 9: 73-78
2.
Henkel,R und Schill,W-B (1998)
Methoden der Spermatozoenseparation zur homologen Insemination.
Gynäkol Prax 22: 251-261
3.
Henkel,R and Schill,W-B (1998)
Sperm separation in patients with urogenital infections.
Andrologia 30 (Suppl. 1): 91-97
4.
Schill,W-B and Henkel,R (1999)
Advancement in biochemical assays in andrology.
Asian J Androl 1: 45-51
5.
Henkel,R, Maaß,G, Hajimohammad,M, Menkveld,R, Stalf,T, Villegas,J, Sánchez,R,
Kruger,TF and Schill,W-B (2003)
Urogenital inflammation: Changes of leukocytes and ROS.
Andrologia 35: 309-313
6.
Henkel,R and Schill,W-B (2003)
Sperm preparation for ART.
Reprod Biol Endocrinol 1: 108
7.
Gonzales,GF, Muñoz,G, Sánchez,R, Henkel,R, Gallegos-Avila,G, Díaz-Gutierrez,O,
Vigil,P, Vásquez,F, Kortebani,G, Mazzolli,A and Bustos-Obregón,E (2004)
Update on the impact of Chlamydia trachomatis infection on male fertility.
Andrologia 36: 1-23
8.
Henkel,R (2004)
Sperm functional assays.
FertiMagazine 11
9.
Henkel,R, Maaß,G, Bödeker,R-H, Scheibelhut,C, Stalf,T, Mehnert,C, Schuppe,H-C,
Jung,A and Schill,W-B (2005)
Sperm function and assisted reproduction technology.
Reprod Med Biol 4: 7-30
10.
Henkel,R (2008)
Sperm function tests.
Overview on modern ejaculate analysis EAU/EBU update series
(submitted)
21
Prof. Ralf Henkel, PhD
22
Book Chapters:
1.
Schill,W-B, Henkel,R and Miska,W (1994)
Biotests of sperm function.
In: Fertility and Sterility. Progress in Research and Practice. The Proceedings of the XIV.
World Congress on Fertility and Sterility, Caracas, Venezuela, November 1992;
Rodriguez-Armaz,O, Baumgartner,W and Burgos-Briceno,L (eds.) The Parthenon
Publishing Group, London, New York, p. 3-17
2.
Miska,W, Finkenzeller,C, Geiger,R, Henkel,R and Schill,W-B (1994)
Zona binding assay using a bioluminescence-enhanced detection system.
In: Campbell,AK, Kricka,LJ and Stanley,RE (eds.); Bioluminescence and
Chemiluminescence. Fundamentals and Applied Aspects., John Wiley Ltd. Sussex, UK,
p. 293-296
3.
Schill,W-B, Köhn,FM, Henkel,R and Haidl,G (1995)
Biochemical aspects of semen analysis.
In: Hedon,B, Bringer,J and Mares,P (eds.), Fertility and Sterility. A Current Overview, The
Parthenon Publishing Group, New York, London, pp. 303-309
4.
Köhn,F-M, Henkel,R, El-Mulla,KF and Schill,W-B (1995)
Physiopathology of acrosome dysfunctions.
In: Human sperm acrosome reaction. pp 327-338; Colloque INSERM/ John Libbey
Eurotext Ltd. London Vol. 236; (eds. P. Fénichel, J. Parinaud)
5.
Coetzee,K and Henkel,RR (1996)
The human sperm acrosome reaction.
In: Acosta,AA and Kruger,TF (eds.) Human Spermatozoa in Assisted Reproduction 2nd
Edition; The Parthenon Publishing Group, New York, London, pp. 215-224
6.
Franken,DR, Claassens,OE and Henkel,RR (1996)
Sperm preparation techniques and X/Y chromosome separation.
In: Acosta,AA and Kruger,TF (eds.) Human Spermatozoa in Assisted Reproduction 2nd
Edition; The Parthenon Publishing Group, New York, London, pp. 277-294
7.
Kruger,TF, Franken,DR, Henkel,RR and Oehninger,S (1996)
Prediction of sperm fertilizing potential.
In: Acosta,AA and Kruger,TF (eds.) Human Spermatozoa in Assisted Reproduction 2nd
Edition; The Parthenon Publishing Group, New York, London, pp. 295-308
8.
Miska,W, Monsees,T, Franken,DR, and Henkel,R (1997)
Evaluation of the bioluminescence-enhanced zona binding assay.
In: Hastings,JW, Kricka,LJ and Stanley,RE (eds.); Bioluminescence and
Chemiluminescence. Molecular Reporting with Photons, John Wiley & Sons, Chichester,
UK, pp. 315-318
9.
Henkel,R (1998)
Ejakulat.
In: Krause,W und Weidner,W (eds.) Andrologie - Krankheiten der männlichen
Geschlechtsorgane (3rd edition).
Ferdinand Enke Verlag, Stuttgart, pp. 26-34
10.
Henkel,R (1998)
Die Bedeutung funktioneller Parameter von Spermatozoen für den Fertilisationsprozeß.
Shaker Verlag, Aachen
Prof. Ralf Henkel, PhD
23
11.
Miska,W, Sánchez,R, Schill,W-B and Henkel,R (1999)
Sperm separation with SpermFertil distinguishes between reactive oxygen species
generated by sperm or leukocytes.
In: Roda,A, Pazzagli,M, Kricka,LJ and Stanley,PE (eds.); Bioluminescence and
Chemiluminescence. Perspectives for the 21st Century; John Wiley & Sons Chichester,
New York, Weinheim, Brisbane, Singapore, Toronto, pp. 315-318
12.
Miska,W, Schill,W-B, Henkel,R and Sánchez,R (2001)
Possible in vivo modulation of human sperm acrosome reaction by a CBG-like protein.
Andrology in the 21st Century, Eds.: B. Robaire, H, Chemes, C.R. Morales; Medimont
Medical Publications, Englewood, USA, pp. 83-88
13.
Henkel,R (2005)
Spermatozoenfunktionstests.
In: Schill,W-B, Bretzel,RG, & Weidner,W (eds.); MännerMedizin.
Urban & Fischer Verlag, München, Jena, Germany, pp.411-419
14.
Hoogendijk,CF and Henkel,R (2007)
The pathophysiology and genetics of human male reproduction.
In: Kruger,TF, Oehninger,S (eds.); Male Infertility - Diagnosis and Treatment; Informa UK
Ltd., Oxon, UK; pp. 35-48
15.
Henkel,R (2007)
Detection of DNA damage in sperm.
In: Kruger,TF, Oehninger,S (eds.); Male Infertility - Diagnosis and Treatment; Informa UK
Ltd., Oxon, UK; pp. 225-238
16.
Henkel,R (2007)
DNA and its influence on fertilization and pregnancy.
In: Kruger,TF, Oehninger,S (eds.); Male Infertility - Diagnosis and Treatment; Informa UK
Ltd., Oxon, UK; pp. 277-290
17.
Henkel,R (2007)
DNA based sperm assessment.
In: Kruger,TF, van der Spuy,Z, Kempers,RD (eds); Advances in Fertility Studies and
Reproductive Medicine – IFFS 2007; Juta, Cape Town, South Africa; pp. 284-292
18.
Henkel,R (2008)
Influence of Sperm DNA Damage in Fertilization and Pregnancy.
In: Greco,E (Ed.); Male Infertility and ART. PACINIeditore Medicina, Pisa, Italy; pp. 5776
19.
Henkel,R (2009)
ROS and sperm DNA integrity – Implications of male accessory gland infections.
In: Giwercman,A, Tournaye,H, Björndahl,L, Weidner,W (eds) Clinical Andrology, Informa
Healthcare (incorporating Parthenon Publishing, Marcel Dekker, and Taylor & Francis
Medical (London) (in press)
Prof. Ralf Henkel, PhD
24
Abstracts:
1.
Dannhorn,D, Henkel,R und Kirchner,C (1988)
Synthese von Uteroglobin in der Blastozyste des Kaninchens? Nachweis durch
Autoradiographie und Immunocytochemie.
Zuchthygiene 23, 135
2.
Wirth,B, Dannhorn,D, Henkel,R und Kirchner,C (1989)
Einfluß des Antiprogesterons ZK 98.299 auf des Kaninchenuterus in der
Präimplantationsphase.
Zuchthygiene 24, 151
3.
Henkel,R, Dannhorn,DR, Petzoldt,U und Kirchner,C (1989)
Polyvinylpyrrolidon als Proteinersatz in der in-vitro Kultur von Kaninchenblastozysten.
Fortschritte der Fertilitätsforschung 18, 310
4.
Henkel,R, Haidl,G, Friedrich,K, Miska,W und Gips,H (1991)
Charakterisierung der Mantelfasern humaner Spermatozoen (Characterization of Human
"Outer Dense Fibers").
Zuchthygiene 26: 157
5.
Haidl,G, und Henkel,R (1991)
Neue Aspekte zu einer auf defekten Mantelfasern beruhenden Flagellumstörung.
Alete Wissenschaftlicher Dienst (1991) No. 6, p. 97
6.
Henkel,R, Müller,C, Hornik,S, Weißmann,N, Haidl,G, Schill,W-B und Gips,H (1991)
Zusammenhang zwischen Akrosinaktivität, Chromatinkondensation, akrosomaler Reaktion
und Befruchtungsfähigkeit menschlicher Spermatozoen in der IVF.
Alete Wissenschaftlicher Dienst (1991) No.40, p. 145
7.
Henkel,R, Friedrich,K, Haidl,G und Miska,W (1991)
Biochemische Untersuchungen der "Outer Dense Fibers".
Alete Wissenschaftlicher Dienst (1991) No. P 1, p. 196
8.
Fehl,P, Henkel,R und Miska,W (1991)
Induktion der Akrosomreaktion durch humane Follikularflüssigkeit.
Alete Wissenschaftlicher Dienst (1991) No. P 2, p. 197
9.
Haidl,G, Henkel,R, Miska,W and Friedrich,K (1991)
Composition of human outer dense fibers and their significance to flagellar movement.
In: The Male Germ Cell: Spermatogonium to Fertilization, p 134
10.
Henkel,R, Stalf,T, Miska,W und Gips,H (1992)
Weitere proteinchemische Untersuchungen der "Outer Dense Fibers" humaner
Spermatozoen.
Reprod Dom Anim 27: p 170, No. 5
11.
Haidl,G and Henkel,R (1992)
Isolation and partial characterization of the outer dense fibres of human spermatozoa.
Arch Dermatol Res 284: 58
12.
Henkel,R, Müller,C, Miska,W and Gips,H (1992)
The acrosome reaction is a predictive parameter in rating the fertilizing capacity of human
spermatozoa for IVF.
XIV. World Congress on Fertility and Sterility, No. 55, p. 50, Caracas, Venezuela
Prof. Ralf Henkel, PhD
25
13.
Henkel,R, Stalf,T, Miska,W, Gips,H and Schill,W-B (1992)
Isolation and partial characterization of the outer dense fiber proteins of human
spermatozoa.
XIV. World Congress on Fertility and Sterility, No. 290, p. 114, Caracas, Venezuela
14.
Stalf,T, Henkel,R, Miska,W und Schill,W.-B. (1993)
Neue Erkenntnisse zu den Mantelfasern humaner Spermatozoen.
In: 26. Tagung über Physiologie und Pathologie der Fortpflanzung (Rath,D, Hoppen,HO,
Hrsg). Paul Parey Scientific Publishers, Berlin, Hamburg, S 147
15.
Schill,W-B, Henkel,R, Müller,C, Miska,W and Gips,H (1993)
Evaluation of acrosomal reaction by low temperature in human spermatozoa is of
predictive value for IVF.
V. International Congress of Andrology 02.-06.05.93, Tokyo, Japan; Miniposters, p 18
16.
Miska,W, Henkel,R und Stalf,T (1993)
Neue Aspekte zur Physiologie der Mantelfasern humaner Spermatozoen.
Dreiländertagung "Fertilität und Sterilität" 06.-08.05.93, Lugano,Switzerland;
Abstractband: p. 12
17.
Henkel,R, Müller,C, Miska,W, Schill,W-B and Gips,H (1993)
Evaluation of acrosin activity by gelatinolysis is predictive for IVF.
J Assist Reprod Genet 10: 280 S
18.
Henkel,R (1993)
Sperma-Aufbereitungstechniken als Vorbedingung für die Assistierte Reproduktion.
Jahrestagung der Deutschen Gesellschaft für Andrologie, 24.-25.09.93, Hamburg; Abstract
book
19.
Henkel,R, Müller,C, Miska,W, Schill,W-B, Kleinstein,J and Gips,H (1993)
Gelatinolysis: A simple assay to evaluate acrosin activity to predict fertilization in IVF.
J Reprod Fertil Abstract Series 12: 56
20.
Schill,W-B, Henkel,R, Sanchez,R, Khanaga,O, Turley,H, Haidl,G and Gips,H (1994)
Sperm function tests: do they have any predictive value?
Hum Reprod 9 Suppl. 4: 94-95
21.
Henkel,R, Franken,DR, Schill,W-B and Lombard,CJ (1994)
The selective capacity of glass wool filtration for normal chromatin condensed human
spermatozoa: A possible therapeutic modality for male factor cases?
Program of the 38. Academic Yearday, 04.08.94, University of Stellenbosch, p 83
22.
Henkel,R, Müller,C, Miska,W, Schill,W-B, Kleinstein,J and Gips,H (1994)
Gelatinolysis: A simple assay to evaluate acrosin activity predicts fertilization in IVF
Program of the 38. Academic Yearday, 04.08.94, University of Stellenbosch, p 87
23.
Henkel,R, Franken,DR, Schill,W-B and Lombard,CJ (1994)
The selective capacity of glass wool filtration for normal chromatin condensed human
spermatozoa: A possible therapeutic modality for male factor cases.
27th Congress of the South African Society of Obstetricians & Gynaecologists,
07.-11.08.94, Sun City, South Africa, Abstract book
Prof. Ralf Henkel, PhD
26
24.
Henkel,R, Kaskar,K, Schill,W-B and Franken,DR (1994)
Improvements of sperm binding to immature human oocytes by incubation in a chemically
defined medium.
27th Congress of the South African Society of Obstetricians & Gynaecologists,
07.-11.08.94, Sun City, South Africa, Abstract book
25.
Kruger,TF, Henkel,R and Oehninger,SC (1994)
Prediction of sperm fertilizing potential.
27th Congress of the South African Society of Obstetricians & Gynaecologists,
07.-11.08.94, Sun City, South Africa, Abstract book
26.
Henkel,R, Kaskar,K, Schill,W-B and Franken,DR (1994)
Improvement of sperm binding to immature human oocytes by incubation in a chemically
defined medium.
Proceedings of the 22nd Annual Congress Physiology Society of Southern Africa p 55
27.
Henkel,R, Franken,DR, Schill,W-B and Lombard,CJ (1994)
The selective capacity of glass wool filtration for normal chromatin condensed human
spermatozoa: A possible therapeutic modality for male factor cases?
Proceedings of the 22nd Annual Congress Physiology Society of Southern Africa
pp 56-57
28.
Henkel,R, Franken,DR and Lombard,CJ (1994)
The selective capacity of glass wool filtration for normal chromatin condensed human
spermatozoa: A therapeutic modality for male factor cases?
Abstract book of the 50. Meeting of the American Fertility Society, P-231, p. S195
29.
Schaller,J, Henkel,R, Glander,H-J and Schill,W-B (1995)
Investigation of adhesion molecules and matrix proteins on human spermatozoa with
different binding and penetration properties in the HOP-test.
Arch Dermatol Res 287: 360
30.
Henkel,R, Cooper,S, Franken,DR, Kaskar,K and Schill,W-B (1995)
Structural changes of zona pellucida due to incubation in a chemically defined medium
cause improvement of sperm binding.
Reprod Dom Anim Suppl. 3: 107
31.
Henkel,R, Franken,DR, Kaskar,K, Schill,W-B and Kruger,TF (1995)
Inhibition of zona pellucida binding of human spermatozoa following exposure to
solubilized human zonae pellucidae is due to acrosomal loss.
Reprod Dom Anim Suppl. 3: 108
32.
Schalles,UK, Villegas,J, Henkel,R und Miska,W (1995)
Immunelektronenmikroskopische Lokalisierung eines 30 kDa Polypeptids in den
Mantelfasern von Spermatozoen verschiedener Säugetierspezies.
Reprod Dom Anim Suppl. 3: 98
33.
Finkenzeller,Ch, Miska,W, Henkel,R und Schill,W-B (1995)
Entwicklung eines Zonabindungs-Assays mittels enzymverstärkter Biolumineszenz.
Reprod Dom Anim Suppl. 3: 106
34.
Schaller,J, Henkel,R, Glander,H-J and Schill,W-B (1995)
Adhäsionsmoleküle an humanen Spermatozoen mit unterschiedlichen Bindungs- und
Penetrationseigenschaften im HOP-Test.
In: Gollnick, KH, Blume, U, Zouboulis, C (Hrsg.) Abstract-Band 38. Tagung der
Deutschen Dermatologischen Gesellschaft, Busse Druck, Herford, p 73
Prof. Ralf Henkel, PhD
27
35.
Henkel,R, Schaller,J, Glander,H-J and Schill,W-B (1995)
Investigation of adhesion molecules and matrix proteins on human sperm with different
binding and penetration properties in the HOP-test.
J Assisted Reprod Genet 12: 169S
36.
Henkel,R, Cooper,S, Franken,DR, Kaskar,K, Schill,W-B and Habenicht,U-F (1995)
Structural changes of zona pellucida due to incubation in a chemically defined medium
cause improvement of sperm binding.
J Assisted Reprod Genet 12: 49S
37.
Henkel,R, Franken,DR, Lombard,CJ and Schill,W-B (1995)
The selective capacity of glass wool filtration for normal chromatin condensed human
spermatozoa: A possible therapeutic modality for male factor cases?
J Assisted Reprod Genet 12: 169S
38.
Henkel,R, Franken,DR, Schill,W-B and Habenicht,U-F (1995)
Dose- and time dependent induction of human sperm acrosome reaction by means of
solubilized zona pellucida proteins.
J Assisted Reprod Genet 12: 129S
39.
Henkel,R, Schaller,J, Glander,H-J and Schill,W-B (1995)
Changes in expression of adhesion molecules on human sperm membrane after acrosome
reaction.
Hum Reprod 10: Abstract Book 2, p. 91
40.
Henkel,R, Cooper,S, Kaskar,K, Schill,W-B, Franken,DR and Habenicht,U-F (1995)
Improvement of sperm binding due to structural changes of human zona pellucida.
Hum Reprod 10: Abstract Book 2, p. 39
41.
Stalf,T, Sanchez,R, Henkel,R, Khanaga,O, Turley,H, Schill,W-B and Gips,H (1995)
Comparison between two methods of sperm preparation for intracytoplasmic sperm
injection.
Hum Reprod 10: Abstract Book 2, p. 91
42.
Baltes,P, Henkel,R and Miska,W (1995)
Further findings concerning the nature and function of the acrosome reaction-inducing
substance (ARIS) of human follicular fluid (hFF).
Hum Reprod 10: Abstract Book 2, p. 91
43.
Schalles,UK, Villegas,J, Henkel,R and Miska,W (1995)
Evidence for an immunological difference among the medulla and cortex in mammalian
sperm tail outer dense fibres (ODF).
Hum Reprod 10: Abstract Book 2, p. 92
44.
Sanchez,R, Concha,M, Ichikawa,T, Henkel,R and Schill,W-B (1995)
Glass wool filtration reduces reactive oxygen species by elimination of leukocytes in
oligozoospermic patients.
Contracept. Fertil. Sex. 23: Suppl. 9, S85; XV. World Congress on Fertility and Sterility,
17.-22.09.95, Montpellier, France
45.
Franken,DR, Henkel,R, Kaskar,K and Schill,W-B (1995)
Chemical manipulation of immature human zona pellucida enhances sperm binding.
Abstract book of the 51. Meeting of the American Society for Reproductive Medicine,
P-185, p. S179
Prof. Ralf Henkel, PhD
28
46.
Henkel,R, Franken,DR, Schill,W-B and Habenicht,U-F (1995)
Studies on the kinetics of human sperm acrosome reaction.
Abstract book of the 51. Meeting of the American Society for Reproductive Medicine,
P-175, p. S174
47.
Baltes,P, Sanchez,R, Schalles,UK, Villegas,J, Peña,P, Henkel,R, Turley,H and Miska,W
(1995)
Origin and nature of the acrosome reaction-inducing substance (ARIS) of human follicular
fluid (hFF).
In: Human sperm acrosome reaction. pp 400-401; Colloque INSERM/ John Libbey
Eurotext Ltd. London Vol. 236; (eds. P. Fénichel, J. Parinaud)
48.
Henkel,R, Franken,DR, Maritz,JS, Schill,W-B and Habenicht,U-F (1995)
Studies on the kinetics of human sperm acrosome reaction. A mathematical model for
assessment.
In: Human sperm acrosome reaction. pp 454-455; Colloque INSERM/ John Libbey
Eurotext Ltd. London Vol. 236; (eds. P. Fénichel, J. Parinaud)
49.
Franken,DR, Henkel,R, Kaskar,K and Habenicht,U-F (1995)
Inhibition of zona binding using solubilized human zona pellucida.
In: Human sperm acrosome reaction. p 403; Colloque INSERM/ John Libbey Eurotext Ltd.
London Vol. 236; (eds. P. Fénichel, J. Parinaud)
50.
Franken,DR, Henkel,R, Kaskar,K, Schill,W-B and Habenicht,U-F (1995)
The influence of solubilized human zona pellucida on zona binding and acrosome reaction
of human sperm.
9th Biennial Congress of the Southern African Society of Reproductive Biology,
07.-08.06.95
51.
Franken,DR, Henkel,R, Kaskar,K and Schill,W-B (1995)
The importance of the human acrosome during zona pellucida binding.
9th Biennial Congress of the Southern African Society of Reproductive Biology,
07.-08.06.95
52.
Henkel,R, Bittner,J, Weber,R, Hüther,F, Schill,W-B und Miska,W (1995)
Entwicklung einer Methode zur getrennten Bestimmung von Zink in Kopf und Flagellum
menschlicher Spermatozoen.
J Fertilität Reproduktion 5: 54
53.
Franken,DR, Henkel,R, Kaskar,K and Habenicht,U-F (1995)
Inhibition of zona binding using solubilized human zona pellucida: Defining bio-assay
conditions to evaluate zona pellucida binding characteristics.
Int. Symposium, Andrology in the Nineties; 18.-21.10.95, Genk, Belgium; Abstract Book,
p1
54.
Franken,DR, Henkel,R, Cooper,S, Kaskar,K and Schill,W-B (1995)
Chemical manipulation of immature human zona pellucida enhances sperm binding.
Int Symposium, Andrology in the Nineties; 18.-21.10.95, Genk, Belgium; Abstract Book
p2
Prof. Ralf Henkel, PhD
29
55.
Oeda,T, Henkel,R, Schill,W-B and Ohmori,H (1996)
Scavenging effect of N-Acetyl-L-cysteine (ACC) for reactive oxygen species (ROS) from
human semen. A possible therapy in male factor infertility?
Reduzierung von reaktiven Sauerstoffspezies (ROS) in menschlichem Ejakulat durch
N-Acetyl-L-Cystein (ACC). Eine mögliche Therapie für die männliche Infertilität?
Reprod Dom Anim 30: 353
56.
Sánchez,R, Baltes,P, Peña,P, Villegas,J, Henkel,R and Miska,W (1996)
Immunohistochemical localization of a CBG-like SERPIN in human fallopian tubes at
various reproductive stages.
Immunhistochemische Lokalisierung eines CBG-ähnlichen SERPINs im menschlichen
Eileiter zu verschiedenen Zeiten des Zyklus.
Reprod Dom Anim 30: 449
57.
Henkel,R, Ichikawa,T, Sánchez,R, Miska,W and Schill,W-B (1996)
Effect of reactive oxygen species on human sperm motility.
Einfluß reaktiver Sauerstoffspezies auf die Motilität menschlicher Spermatozoen.
Reprod Dom Anim 30: 385
58.
Miska,W, Baltes,P, Sanchez,R, Henkel,R and Schill,W-B (1996)
Possible involvement of a CBG-like SERPIN in in vivo modulation of the acrosome
reaction.
International Symposium on the Chemistry and Biology of SERPINS, 13.04.-16.04.96,
Chapel Hill, USA (accepted for Oral and Poster presentation)
59.
Henkel,R, Finkenzeller,Ch, Monsees,T, Franken,DR, Schill,W-B and Miska,W (1996)
Development of a highly sensitive, bioluminescence enhanced zona binding assay.
Hum Reprod 11: 41-42
60.
Oeda,T, Ichikawa,T, Henkel,R, Nagai,A, Schill,W-B and Ohmori,H (1996)
N-Acetyl-L-Cysteine scavenges reactive oxygen species (ROS) from human semen.
Abstract book of the 84th Meeting of the Japanese Urological Society, 03.-06.04.96,
Okayama, Japan
61.
Oeda,T, Henkel,R, Ichikawa,T, Nagai,A, Ozawa,H, Akiyama,H, Akiyama,M,
Schill,W-B and Ohmori,H (1996)
In vitro effect of N-acetyl-L-cysteine on reactive oxygen species in human semen.
Abstract book of the 15th Annual Meeting of the Japanese Society of Andrology,
19.-20.07.96, Kurashiki, Japan
62.
Henkel,R (1996)
Tests of sperm functions and the prediction of the outcome of assisted reproductive
techniques.
Newsletter: International Society of Andrology 17: p2; 7th Annual Meeting of the German
Society of Andrology, Marburg, 29.-30.09.95
63.
Miska,W, Monsees,T, Finkenzeller,Ch, Franken,DR, Schill,W-B and Henkel,R (1996)
Evaluation of the bioluminescence-enhanced zona binding assay.
J Biolum Chemilum 11: 237
64.
Miska,W, Schalles,UK, Villegas,J and Henkel,R (1997)
Immunelectron Microscopic Studies on Outer Dense Fibres.
Adv. Exp. Med. Biol. Vol. 424: 241-242
Prof. Ralf Henkel, PhD
65.
Baltes,P, Sánchez,R, Henkel,R, and Miska,W (1997)
Putative role of a SERPIN in modulation of acrosome reaction
Adv. Exp. Med. Biol. Vol. 424: 239-240
66.
Köhn,FM, Henkel,R, Eberl,M and Schill,W-B (1997)
Inhibition of angiotensin converting enzyme (ACE) by captopril reduces human sperm
binding to the plasma membrane of zona-free hamster oocytes.
Reprod Dom Anim 32: 11
67.
Henkel,R, Bittner,J, Weber,R and Miska,W (1997)
The importance of flagellar zinc for human sperm motility.
Int J Androl 20, Suppl. 1: 10
68.
Oeda,T, Henkel,R, Nagai,A, Schill, W-B and Ohmori,H (1997)
N-Acetyl-L-Cysteine scavenges reactive oxygen species in human semen.
Int J Androl 20, Suppl. 1: 16
69.
Müller,C, Stürzebecher,J, Hesse,S, Schill,W-B, Henkel,R and Miska,W (1997)
Evaluation of benzamidine-type acrosin inhibitors.
Int J Androl 20, Suppl. 1: 18
70.
Miska,W, Baltes,P, Sánchez,R and Henkel,R (1997)
Characterization of the acrosome reaction-inducing substance of human follicular fluid.
Int J Androl 20, Suppl. 1: 50
71.
Henkel,R, Monsees,T, Franken,DR and Miska,W (1997)
Development of a new zona pellucida binding assay.
41st Academic Yearday of the University of Stellenbosch, 20.08.97-21.08.97,
Stellenbosch, South Africa (Abstractbook: p80)
72.
Henkel,R, Oeda,T, Ohmori,H and Schill,W-B (1997)
Reduzierung von reaktiven Sauerstoffspezies in menschlichem Ejakulat durch
N-Acetyl-L-Cystein.
IX. Jahrestagung der Deutschen Gesellschaft für Andrologie, 12.09.-13.09.97, Lübeck,
Germany (Abstractbook)
73.
Monsees,TK, Henkel,R, Miska,W and Schill (1997)
Einfluß von Gossypol auf die sekretorische Funktion von Sertoli-Zellen.
IX. Jahrestagung der Deutschen Gesellschaft für Andrologie, 12.09.-13.09.97, Lübeck,
Germany (Abstractbook)
74.
Henkel,R, Monsees,T, Müller,C, Stalf,T, Franken,DR, Gips,H und Schill,W-B (1997)
Einsatz von erfolglos fertilisierten Eizellen im Hemizona Assay nach struktureller
Veränderung der Zona.
Reprod Dom Anim (Supplement 4): 111
75.
Müller,C, Stürzebecher,J, Hesse,S, Henkel,R, Schill,W-B und Miska,W (1997)
Charakterisierung verschiedener Akrosininhibitoren vom Benzamidintyp.
Reprod Dom Anim (Supplement 4): 136
76.
Henkel,R, Bittner,J, Weber,R, Miska,W and Schill,W-B (1998)
Decreased sperm motility in older men might be due to increased flagellar zinc
concentration.
1st World Congress on The Aging Male, 05.02.-08.02.98, Geneva, Switzerland
30
Prof. Ralf Henkel, PhD
31
77.
Henkel,R, Müller,C, Stalf,T, Schill,W-B and Franken,DR (1998)
Use of failed-ferilized oocytes for diagnostic zona binding purposes after sperm binding
improvement.
29th SASOG Congress, 08.03.-12.03.98, Stellenbosch, South Africa, Abstractbook
78.
Henkel,R, Sánchez,R and Schill,W-B (1998)
Sperm separation with SpermFertil® distinguishes between reactive oxygen species
generated by sperm or leukocytes.
29th SASOG Congress, 08.03.-12.03.98, Stellenbosch, South Africa, Abstractbook
79.
Henkel,R and Schill,W-B (1998)
Multiple regression analysis of sperm motility and different parameters of genital tract
inflammation.
Hum Reprod 13: 279-280
80.
Huwe,P, Gesell,St, Diemer,Th, Henkel,R and Weidner,W (1998)
Influence of antibiotics on sperm motility in vitro.
Hum Reprod 13: 147
81.
Sánchez,R, Baltes,P, Peña,P, Villegas,J, Henkel,R, Schill,W-B, Miska,W (1998)
Presence of a CBG-like SERPIN in the female genital tract.
Andrologia 30: 175-176
82.
Henkel,R, Bittner,J, Weber,R, Schill,W-B and Miska,W (1998)
Determination of zinc in the human sperm flagellum and its correlation to motility.
Andrologia 30: 173-174
83.
Müller,C, Henkel,R, Stürzebecher,J, Hesse,S, Schill,W-B and Miska,W (1998)
Inhibition of human acrosin by low molecular mass inhibitors of the benzamidine-type.
Andrologia 30: 183
84.
Miska,W, Sánchez,R, Schill,W-B and Henkel,R (1998)
Sperm separation with SpermFertil® distinguishes between reactive oxygen species
generated by sperm or leukocytes.
J Biolum Chemilum 13: 203
85.
Müller,C, Henkel,R and Schill,W-B (1998)
The use of the hypoosmotic swelling test to predict fertilization in IVF.
Fertil Steril 70 (Suppl 1): S265, P-443
86.
Sánchez,R, Peña,P, Henkel,R and Miska,W (1998)
Immunohistochemical localization of a CBG-like SERPIN in the human sperm acrosome.
Fertil Steril 70 (Suppl 1): S388, P-839
87.
Henkel,R, Stalf,T, Seefeldt-Schmidt,B, Schill,W-B und Miska,W (1998)
Neue Untersuchungen zur Biochemie und Physiologie der Mantelfasern von
Säugerspermatozoen.
10. Jahrestagung der Deutschen Gesellschaft für Andrologie, 08.-10.10.98, Münster,
Germany; Abstractbook p. 44
88.
Miska,W, Zwartenkot,E, Baltes,P, Linder,M, Schill,W-B und Henkel,R (1998)
Differentielle MALDI-ToF-MS-Analyse eines CBG-ähnlichen Proteins aus
unterschiedlichen Proben.
10. Jahrestagung der Deutschen Gesellschaft für Andrologie, 08.-10.10.98, Münster,
Germany; Abstractbook p. 55
Prof. Ralf Henkel, PhD
32
89.
Köhn,FM, Müller,C, Drescher,D, El Mulla,KF, Neukamm,C, Henkel,R, Habenicht,UF and
Schill,W-B (1998)
Effect of angiotensin converting enzyme (ACE) and angiotensins on human sperm
functions.
10. Jahrestagung der Deutschen Gesellschaft für Andrologie, 08.-10.10.98, Münster,
Germany; Abstractbook p. 46
90.
Huwe,P, Gesell,S, Diemer,T, Henkel,R und Weidner,W (1998)
Der Einfluß verschiedener Antibiotika auf die Motilität von humanen Spermatozoen in
vitro.
10. Jahrestagung der Deutschen Gesellschaft für Andrologie, 08.-10.10.98, Münster,
Germany; Abstractbook p. 48
91.
Miska,W, Sánchez,R, Miska,G, Schill,W-B and Henkel,R (1999)
Differentiation of reactive oxygen species generated in sperm or leukocytes.
Reprod Dom Anim 34: 42
92.
Henkel,R, Hanschke,A and Schill,W-B (1999)
Impairment of sperm motility by inflammatory parameters.
Reprod Dom Anim 34: 26
93.
Henkel,R, Müller,C and Schill,W-B (1999)
Evaluation of the hypoosmotic swelling test for use in male factor infertility diagnosis.
Reprod Dom Anim 34: 27
94.
Seefeldt-Schmidt,B, Henkel,R and Miska,W (1999)
Biochemical and immunological characterization of low molecular outer dense fiber
polypeptides of bull spermatozoa.
Reprod Dom Anim 34: 44
95.
Sánchez,R, Peña,P, Hanschke,A, Schill,W-B and Henkel,R (1999)
Seasonal changes in human sperm chromatin condensation. First cases from the southern
hemisphere (Chile)
Reprod Dom Anim 34: 15
96.
Miska W, Baltes P, Sánchez R and Henkel R (1999)
In vivo modulation of the acrosome reaction in the female genital tract by a CBG-like
SERPIN.
SERPINS, 27.06.-01.07.99, Cambridge, UK, Abstract book PM72
97.
Henkel,R, Bittner,J, Weber,R, Miska,W, Schill,W-B (1999)
Decreased sperm motility in older men might be due to increased flagellar zinc
concentration.
5th Symposium of Andrology in the Nineties, Cape Town, South Africa, 25.-27.03.99
Abstractbook P-11
98.
Miska,W, Baltes,P, Sánchez,R, Schill,W-B and Henkel,R (1999)
Acrosome reaction is in vivo modulated by a CBG-like protein.
5th Symposium of Andrology in the Nineties, Cape Town, South Africa, 25.-27.03.99
Abstractbook P-12
99.
Seefeldt-Schmidt,B, Henkel,R, Schill,W-B and Miska,W (1999)
Biochemical and immunological characterization of low-molecular mass outer dense fibre
proteins of bovine spermatozoa.
Andrologia 31: 388
Prof. Ralf Henkel, PhD
33
100. Miska,W, Zwartenkot,E, Baltes,P, Sánchez,R, Schill,W-B and Henkel,R (2000)
MALDI-ToF-MS analysis of a CBG-like protein.
Reprod Dom Anim 35: 30
101. Miska,W, Seefeldt-Schmidt,B and Henkel,R (2000)
Characterization of two distinct polypeptides in bovine outer dense fibers.
Reprod Dom Anim 35: 12-13
102. Henkel,R, Defosse,K, Weißmann,N and Miska,W (2000)
Assessment of the energy consumption of human spermatozoa related to motility.
Reprod Dom Anim 35: 14
103. Henkel,R, Baldauf,Ch, Bittner,J, Miska,W and Weidner,W (2000)
Elimination of zinc from sperm flagella during epididymal transit is important for motility.
Hum Reprod 15: 101-102
104. Henkel,R, Baldauf,Ch, Bittner,J, Miska,W and Weidner,W (2000)
The importance of the elimination of zinc from spermatozoa during epididymal transit for
motility.
Andrologia 32: 369-370
105. Löffler,M, Dietz,C, Hayek-Ouassini,M, Henkel,R and Simmonds,A (2000)
Localization and function of dihydroorotate dehydrogenase of pyrimidine synthesis in
mammalian germ cells.
Abstract book XVIIth International Arginine/Pyrimidine Conference, 09.-12.09.2000,
Valencia, Spain
106. Baldauf,Ch, Miska,W, Weidner,W und Henkel,R (2000)
Zinkeliminierung aus Flagellen ist essentiell für die Spermienmotilität.
Abstract book 50. Kongreß der Deutschen Gesellschaft für Urologie, 20.09.-23.09.00,
Hamburg, Germany
107. Heidorn,F, Henkel,R und Weiler,G (2000)
Sequenzanalyse mitochondrialer DNA an Einzelspermatozoen.
Rechtsmedizin
108. Hayek-Ouassini,M, Fairbanks,LD, Henkel,R, Simmonds,HA, Rudnik,J, Löffler,M (2000)
Determination of pyrimidine and purine metabolites in human seminal plasma.
5th Dies Andrologicus, 25.11.00, Marburg, Germany
109. Villegas,J, Sánchez,R, Soto,L, Risopatrón,J, Bustos,L, Henkel,R (2000)
Metabolitos reactivos de oxigeno: Evaluación del efecto sobre el espermatozoide humano.
Informe preliminar.
Actualidad Andrológica, Asociación Española de Andrología (ASESA)
110. Seefeldt-Schmidt,B, Henkel,R, Schill,W-B und Miska,W (2001)
New aspects concerning the structure of outer dense fibres in bull spermatozoa.
Andrologia 33: 180
111. Baldauf,Ch, Miska,W, Weidner,W and Henkel,R (2001)
Identification of a zinc binding protein in bovine epididymal fluid.
26. Veterinär-Humanmedizinische Gemeinschaftstagung, 22.-23.02.2001, Gießen,
Germany, Abstract book p. 15
Prof. Ralf Henkel, PhD
34
112. Wroblewski,N, Miska,W, Weidner,W, Schill,W-B and Henkel,R (2001)
Influence on human sperm motility by addition of different chelators.
26. Veterinär-Humanmedizinische Gemeinschaftstagung, 22.-23.02.2001, Gießen,
Germany, Abstract book p. 46
113. Seefeldt-Schmidt,B, Henkel,R, Schill,W-B and Miska,W (2001)
Localization of a 11-kDa polypeptide in the outer dense fibers of bull spermatozoa.
26. Veterinär-Humanmedizinische Gemeinschaftstagung, 22.-23.02.2001, Gießen,
Germany, Abstract book p. 71
114. Miska,W, Peña,P, Sánchez,R, Vásquez,B, Vasconcellos,A, Henkel,R (2001)
Immunocytochemical localization of a CBG-like SERPIN in ovarian connective tissue.
26. Veterinär-Humanmedizinische Gemeinschaftstagung, 22.-23.02.2001, Gießen,
Germany, Abstract book p. 22
115. Henkel,R, Defosse,K, Weißmann,N, Weidner,W, Schill,W-B, Miska,W (2001)
Flagellar zinc content and energy consumption of human spermatozoa.
26. Veterinär-Humanmedizinische Gemeinschaftstagung, 22.-23.02.2001, Gießen,
Germany, Abstract book p. 68
116. Stalf,T, Henkel,R, Herrero,J, Hajimohammad,M, Mehnert,C, Gips,H (2001)
DNA-Fragmentierung humaner Spermatozoen und Outcome im IVF/ICSI-Programm.
Organon-Symposium für junge, forschende Reproduktionsmediziner, 04.-06.05.2001,
Freiburg, Germany
117. Miska,W, Henkel,R, Schill,W-B, Sánchez,R (2001)
Possible In Vivo Modulation of Human Sperm Acrosome Reaction by a CBG-like Protein.
J. Androl. (May/June 2001 Supplement) p. 202
118. Henkel,R, Hajimohammad,M, Stalf,T, Mehnert,C, Herrero,J, Menkveld,R, Schill,WB,
Kruger,T, Gips,H (2001)
Influence of DNA integrity on fertilisation and pregnancy.
17th Meeting of the ESHRE, 01.-04.07.2001, Lausanne, Switzerland
119. Menkveld,R, Schill,W-B, Henkel,R (2001)
Seasonal changes of chromatin condensation in human sperm.
45th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2001,
Abstract book
120. Henkel,R, Defosse,K, Weißmann,N, Schill,W-B, Miska,W (2001)
Human sperm zinc content and energy consumption.
45th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2001,
Abstract book
121. Henkel,R, Hajimohammad,M, Stalf,T, Menkveld,R, Schill,W-B, Kruger,T, Gips,H (2001)
Influence of DNA integrity on fertilisation and pregnancy.
45th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2001,
Abstract book
122. Henkel,R, Wroblewski,N, Miska,W, Schill,W-B (2001)
Dose-dependent effect of different chelators on motility of human spermatozoa.
45th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2001,
Abstract book
Prof. Ralf Henkel, PhD
35
123. Henkel,R, Teichmann,U, Schill,W-B (2001)
Influence of different heavy metals on acrosome reaction and motility of human
spermatozoa.
45th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2001,
Abstract book
124. Menkveld,R, El-Garem,Y, Schill,W-B and Henkel,R (2001)
Relationship between acrosome size and acrosome reaction.
45th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2001,
Abstract book
125. Menkveld,R, Schill,W-B, Henkel,R (2001)
Seasonal changes of chromatin condensation in human sperm.
27th Congress of the SASOG, Sun City, South Africa, 19.-22.08.2001, Abstract book
126. Menkveld,R, El-Garem,Y, Schill,W-B and Henkel,R (2001)
Relationship between acrosome size and acrosome reaction.
27th Congress of the SASOG, Sun City, South Africa, 19.-22.08.2001, Abstract book
127. Henkel,R, Hajimohammad,C, Stalf,T, Hoogendijk,C, Menkveld,R, Schill,W-B and
Kruger,TF (2001)
Importance to evaluate sperm DNA fragmentation prior to IVF.
Abstract book der Jahrestagung der Deutschen Gesellschaft für Reproduktionsmedizin, p.
11
128. Wroblewski,N, Miska,W, Schill, W-B and Henkel,R (2001)
Qualitative changes in human sperm motility pattern following administration of chelators.
Abstract book der Jahrestagung der Deutschen Gesellschaft für Reproduktionsmedizin, p. 9
129. Miska,W, Peña,P, Vasconcellos,A, Vásquez,B, Henkel,R, Sánchez,R (2001)
Immunocytochemical localization of transcortin in human ovarian connective tissue.
Abstract book der Jahrestagung der Deutschen Gesellschaft für Reproduktionsmedizin, p.
19
130. Villegas,J, Catalán,S, Soto,L, Henkel,R and Sánchez,R (2001)
Reactive oxygen species (ROS) induce reversible capacitation in human spermatozoa.
Abstract book of the 17th World Congress on Fertility and Sterility, 25.-30.11.2001,
Melbourne, Australia
131. Henkel,R, Jung,A and Schill,W-B (2001)
Molecular aspects of declining sperm motility in older men.
The Aging Male 4: 275
132. Henkel,R, El-Garem,Y, Schill,W-B and Menkveld,R (2002)
Relationship between acrosomal function and morphology.
Tagung über Physiologie und Pathologie der Fortpflanzung, p. 74
133. Monsees,TK, Kos,P, Schill,W-B and Henkel,R (2002)
Bradykinin-degrading proteases in peritubular cells of the rat testis.
Tagung über Physiologie und Pathologie der Fortpflanzung, p. 7
134. Wroblewski,N, Miska,W, Schill,W-B and Henkel,R (2002)
Dose-dependent effect of different chelators on motility of human spermatozoa.
Andrologia 34: 135
Prof. Ralf Henkel, PhD
36
135. Henkel,R, Hajimohammad,M, Stalf, T, Menkveld,R, Schill,W-B, Kruger,TF and Gips,H
(2002)
DNA fragmentation of spermatozoa have an effects on pregnancy but not fertilization rate.
Andrologia 34: 131
136. Henkel,R, Teichmann,U and Schill,W-B (2002)
Influence of different heavy metals on acrosome reaction and motility of human
spermatozoa.
Andrologia 34: 131-132
137. Seefeldt-Schmidt,B, Henkel,R, Schill,W-B, Miska,W (2002)
Localization of a third protein component in mammalian outer dense fibers.
Andrologia 34: 143
138. Henkel,R, Menkveld,R, El-Garem,Y and Schill,W-B (2002)
Acrosomal function is dependent on the size of the acrosome.
Andrologia 34: 132
139. Slavov,M, Henkel,R, Steger,K, Bergmann,M, Weidner,W and Schroeder-Printzen,I (2002)
Chromatin condensation and expression of nuclear proteins in rabbit epididymal and
testicular spermatozoa and spermatids - preliminary results to establish an animal model
for seminal duct obstruction.
Andrologia 34: 128-129
140. Miska,W, Peña,P, Vásquez,B, Vasconcellos,A, Henkel,R and Sánchez,R (2002)
Detection and localization of a transcortin-like substance in ovarian connecting tissue.
Andrologia 34: 133
141. Henkel,R, Baldauf,C, Miska,W, Weidner,W and Schill,W-B (2002)
Zinc eliminated from bull spermatozoa is taken up by cauda epididymis and vas deferens.
Abstract book of the Third International Conference on the Epididymis, 29.05.-01.06.2002,
Charlottesville, Virginia, USA, P40
142. Henkel,R, Maaß,G, Bödeker,H-R, Scheibelhut,C, Stalf,T, Jung,A, Gips,H and Schill,W-B
(2002)
Do sperm function tests contribute to fertility prognosis?
Andrologia 34: 264-265
143. Monsees,TK, Kos,P, Schill,W-B and Henkel,R (2002)
Identification of protease activities in testicular rat peritubular cells.
Andrologia 34: 279
144. Slavov,M, Schroeder-Printzen,I, Henkel,R, Steger,K, Bergmann,M, Failing,K and
Weidner,W (2002)
Determination of chromatin condensation and nuclear proteins in testicular and epididymal
spermatozoa and round spermatids in a standardized rabbit of obstructive azoospermia.
Andrologia 34: 280-281
145. Seefeldt-Schmidt,B, Henkel,R, Schill,W-B and Miska,W (2002)
New findings on the cortical structure of mammalian outer dense fibres.
9th International Symposium on Spermatology, Cape Town, South Africa, 06.-11.10.2002;
Abstractbook p 59
Prof. Ralf Henkel, PhD
37
146. Miska,W, Seefeldt-Schmidt,B, Henkel,R and Schill,W-B (2002)
New findings on the cortical structure of mammalian outer dense fibres.
Proceedings of the 9th International Symposium on Spermatology, Cape Town, South
Africa, 06.-11.10.2002, Monduzzi Editore, Bologna, Italy, Eds.: G. Van der Horst, D.
Franken, R. Bornman, T. Bornman, S. Dyer, pp. 113-116
147. Henkel,R, Maaß,G, Bödeker,R-H, Scheibelhut,C, Stalf,T, Mehnert,C and Schill,W-B
(2002)
Impact of different sperm functions on fertilization and pregnancy.
Asian J Androl 4 (Suppl. 3): 35-37
148. Henkel,R, Baldauf,C, Miska,W, Weidner,W, Schroeder-Printzen,I and Schill,W-B (2002)
Resorption of spermatozoal zinc in epididymis and vas deferens.
2. Tagung des Arbeitskreises Molekularbiologie der DGGEF, 15.-17.11.2002, Münster,
Germany; Abstract book
149. Seefeldt-Schmidt,B, Henkel,R, Schill,W-B and Miska,W (2003)
Localication of a new polypeptide in mammalian outer dense fibres.
Andrologia 35: 11
150. Baldauf,C, Miska,W, Weidner,W, Schill,W-B and Henkel,R (2003)
Principal cells in the cauda epiddymis resorb zinc eliminated from spermatozoa.
Andrologia 35: 3
151. Eickhoff,R, Baldauf,C, Wennemuth,G, Seitz,J, Suga,Y, Henkel,R and Meinhardt,A (2003)
Influence of the macrophage migration inhibitory factor (MIF) on the distribution of zinc
and sulfhydryl groups in maturing rat spermatozoa.
Anal Anat Suppl. 185: 16
152. Stalf,T, Schuppe,HC, Henkel,R, Weidner,W, Schill,W-B, Tinneberg,H-R and Gips,H
(2003)
Limitations for ICSI, MESA, TESE?
Andrologia 35: 181-183
153. Stalf,T, Hajimohammad,M, Hoogendijk,C, Mehnert,C, Menkveld,R, Gips,H, Schill,W-B,
Kruger,TF and Henkel,R (2003)
IVF outcome is related to sperm DNA fragmentation but not to apoptosis.
Hum Reprod 18 Suppl. 1: 151
154. Henkel,R, Baldauf,C, Eickhoff,R, Koyro,H-W and Meinhardt,A (2003)
Influence of the macrophage migration inhibitory factor on sperm zinc content.
Reproduktionsmedizin 19: 237
155. Henkel,R, Kierspel,E, Hajimohammad,M, Stalf,T, Hoogendijk,C, Mehnert,C, Menkveld,R,
Schill,W-B and Kruger TF (2003)
Do reactive oxygen species affect sperm DNA fragmentation, fertilization and pregnancy in
IVF?
Reproduktionsmedizin 19: 227
156. Henkel,R, Kierspel,E, Hajimohammad,M, Stalf,T, Mehnert,C, Hoogendijk,C, Menkveld,R,
Schill,W-B, Gips,H and Kruger,TF (2003)
What causes Sperm DNA Fragmentation-related Pregnancy Failure - Apoptosis or ROS?
3. Tagung des Arbeitskreises Molekularbiologie der DGGEF, 07.-08.11.2003, Gießen,
Germany, Abstract book
Prof. Ralf Henkel, PhD
38
157. Henkel,R, Baldauf,C, Miska,W, Weidner,W and Schill,W-B (2003)
Zinc eliminated from bull spermatozoa is taken up by cauda epididymis and vas deferens.
In: The Third International Conference on the Epididymis, Eds. Hinton,BT & Turner,TT,
The Van Doren Company, Charlottesville, Virginia, USA, p. 332
158. Slavov MK, Schroeder-Printzen I, Henkel R, Steger K, Bergmann M, Weidner W (2003)
Alterations of chromatin condensation and nuclear proteins in testicular and epididymal
spermatozoa and round spermatids in a standardized rabbit model after vasectomy.
J Urol 169 (1545 Suppl. S): 413-414
159. Mehnert,C, Hendrischk,AK, Stalf,T, Tinneberg,H-R, Schill,W-B and Henkel,R (2004)
Establishment of a protein-free primary cell culture of bovine epididymal epithelial cells.
Vet. Med. Austria 91, Suppl. 2: 45
160. Henkel,R, Kierspel,E, Stalf,T, Mehnert,C, Hoogendijk,C, Menkveld,R, Schill,W-B and
Kruger,TF (2004)
Assessment of the effect of intrinsic and extrinsic ROS on sperm functions.
Vet. Med. Austria 91, Suppl. 2: 28-29
161. Schill,W-B and Henkel,R (2004)
Sperm function and outcome of assisted reproduction.
1st World Congress and Workshops on Assisted Fertilization, Conception and Molecular
Reproduction, 13.-19.03.2004, Cairo, Egypt, Abstract book, p 43
162. Stalf,T, Kierspel,E, Menkveld,R, Kruger,TF, Tinneberg,H-R, Schill,W-B and Henkel,R
(2004)
Effect of intrinsic and extrinsic ROS on sperm functions.
Hum Reprod 19: Suppl. 1, i191
163. Hoogendijk,CF, Kruger,TF, Lombard,C and Henkel,R (2004)
Correlation of human sperm DNA fragmentation and apoptosis rate with normal sperm
morphology.
48th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2004;
Abstract book
164. Henkel,R, Mehnert,C, Hendrischk,AK, Stalf,T, Tinneberg,HR and Schill,W-B (2004)
Culture of bovine epididymal epithelial cells in a protein-free cell culture medium.
Andrologia 36: 229
165. Mehnert,C, Schuppe,H-C, Stalf,T, Henkel,R, Weidner,W, Tinneberg,H-R and Schill,W-B
(2004)
Importance of sperm origin for the outcome of ICSI.
Andrologia 36: 184
166. Slavov,M, Diemer,T, Schroeder-Printzen,I, Henkel,R, Steger,K, Bergmann,M and
Weidner,W (2004)
Chromatin condensation and expression of nuclear proteins in spermatozoa and round
spermatids in vasectomized rabbits.
Andrologia 36: 185
167. Hoogendijk,CF, Kruger,TF, de Beer,ML, Siebert,TI, Henkel,R (2005)
Improvement in early human embryo development using SAGE QA Sequential stagespecific culture mediums.
4th BDSA Congress of Obstetrics and Gynaecology, Stellenbosch, South Africa, 27.29.01.2005, Abstract book
Prof. Ralf Henkel, PhD
39
168. Henkel,R, Maaß,G, Bödeker,R-H, Scheibelhut,C, Jung,A, Schuppe,H-C, Stalf,T,
Tinneberg,H-R, Schubert,J, Schill,W-B (2005)
Welchen Beitrag leisten die Spermatozoenfunktionstests zur Fertilitätsdiagnose? - Do
sperm function tests contribute to fertility prognosis?
JDDG 3 Suppl. 1: S20
169. Hoogendijk,CF, Kruger,TF, de Beer,ML, Siebert,TI, Henkel,R (2005)
A Study of two Sequential Mediums: The impact on Embryo Quality and Pregnancy rates.
13th World Congress on In Vitro Fertilization, Assisted Reproduction and Genetics,
Istanbul, Turkey, 26.-29.05.2005 (accepted for oral presentation)
170. Henkel,R, Stalf,T, Mehnert,C, Menkveld,R, Schill,W-B, Schubert,J, Kruger,TF (2005)
Effect of extrinsic ROS on sperm functions.
Int J Androl 28: 37
171. Henkel,R, Maaß,G, Schuppe,H-C, Jung,A, Schubert,J, Schill,W-B (2005)
High flagellar zinc concentration is responsible for decreased sperm motility in ageing
men.
Int J Androl 28: 78
172. Henkel,R, Maaß,G, Schuppe,H-C, Jung,A, Schubert,J, Schill,W-B (2005)
Seasonal changes of α-glucosidase activity in human semen.
Int J Androl 28: 83
173. Henkel,R, Maaß,G, Schuppe,H-C, Jung,A, Schubert,J, Schill,W-B (2005)
Seasonal changes of α-glucosidase activity in human semen.
57. Congress of the German Society for Urology, Düsseldorf, Germany, 21.-24.09.2005,
Abstract book
174. Henkel,R (2005)
The impact of oxidants on sperm function.
Andrologia 37: 205-206
175. Bittorf,K, Henkel,R, Hayatpour,J, Monsees,TK (2005)
Effect of xenoestrogens on primary rat Sertoli cell functions.
Andrologia 37: 237
176. Hinkel,S, Hayatpour,J, Henkel,R, Monsees,TK (2005)
Influence of xenoestrogens on rat Leydig cell functions.
Andrologia 37: 237
177. Jung,A, Schuppe,H-C, Maaß,G, Haidl,G, Schill,W-B, Henkel,R (2005)
Age-related changes in seminal PMN-elastase in men with asymptomatic inflammation of
the genital tract.
Andrologia 37: 244
178. Schuppe,H-C, Maaß,G, Jung,A, Schubert,J, Schill,W-B, Henkel,R (2005)
Jahreszeitliche Schwankungen der α-Glukosidaseaktivität im menschlichen Ejakulat.
J Reproduktionsmed Endokrinol 5: 299-300
179. Schuppe,H-C, Maaß,G, Jung,A, Haidl,G, Schill,W-B, Henkel,R (2005)
Altersabhängiger Anstieg der PMN-Elastase im Seminlaplasma bei Männern mit stillen
asymptomatischen Entzündungsreaktionen des Genitaltraktes.
J Reproduktionsmed Endokrinol 5: 309
Prof. Ralf Henkel, PhD
40
180. Henkel,R, Schuppe,H-C, Maaß,G, Jung,A, Schill,W-B (2005)
Molekulare Ursachen für die abnehmende Spermienmotilität bei älteren Männern.
J Reproduktionsmed Endokrinol 5: 310
181. Ludwig,M, Schuppe,H-C, Diemer,T, Schill,W-B, Weidner,W, Henkel,R (2005)
Chronisches Beckenschmerzsyndrom/chronische Prostatitis beeinträchtigen die
Akrosomreaktion bei menschlichen Spermatozoen.
J Reproduktionsmed Endokrinol 5: 301
182. Schuppe,H-C, Jung,A, Maaß,G, Haidl,G, Schill,W-B, Henkel,R (2006)
A perspective on "inflamm-aging" of the male genital tract: age-related changes in seminal
PMN-elastase.
The Aging Male 9: 48
183. Schuppe,H-C, Maaß,G, Jung,A, Schill,W-B, Henkel,R (2006)
Molecular aspects of declining sperm motility in aging men.
The Aging Male 9: 12
184. Mehnert,C, Schuppe,H-C, Stalf,T, Henkel,R, Tinneberg,H-R (2006)
An in vitro model for epididymal sperm maturation.
Reprod Dom Anim 41 (Suppl .1): 23
185. Ludwig,M, Diemer,T, Schuppe,HC, Schill,W-B, Weidner,W, Henkel,R (2006)
Chronic pelvic pain syndrome/chronic prostatitis (CPPS/CP) perturbs acrosome reaction in
human spermatozoa.
J Urol 175: 524
186. Ludwig,M, Diemer,T, Schuppe,HC, Schill,W-B, Weidner,W, Henkel,R (2006)
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) influences acrosome function
in spermatozoa. Eur Urol Suppl. 5: 216
187. Henkel,R, Sturmhoefel,A, Schreiber,G, Hipler,UC, Zermann,DH, Menkveld,R (2006)
Comparison of three methods to evaluate human sperm morphology.
50th Academic Yearday, Faculty of Health Sciences, Tygerberg Hospital and University of
Stellenbosch, 16.-17.08.2006, Stellenbosch, South Africa, Abstract book
188. Hoogendijk CF, Kruger TF, Henkel R (2006)
Correlation of human sperm DNA fragmentation and apoptosis rate with normal sperm
morphology.
50th Academic Yearday, Faculty of Health Sciences, Tygerberg Hospital and University of
Stellenbosch, 16.-17.08.2006, Stellenbosch, South Africa, Abstract book
189. Mehnert,C, Fechner,C, Stalf,T, Tinneberg,H-R, Henkel,R, Schuppe,H-C (2006)
Ein in-vitro-Modell für die epididymale Spermienreifung.
18. Annual Congress of the German Society of Andrology, Düsseldorf, 07.-09.09.2006
(accepted as Poster and Oral)
190. Henkel,R (2006)
DNA fragmentation of spermatozoa and assisted reproductive technology.
Male Infertility and ART, 06.-07.10.06, Rome, Italy
191. Henkel,R, Schuppe,H-C, Maaβ,G, Jung,A, Haidl,G, Schill,W-B (2006)
Age-related changes in seminal PMN-elastase in men with asymptomatic inflammation of
the genital tract.
Asian J Androl 8 (Suppl. 1): 39
Prof. Ralf Henkel, PhD
41
192. Henkel,R, Maaß,G, Schuppe,H-C, Jung,A, Schill,W-B (2006)
Molecular causes for declining sperm motility in elderly men.
Asian J Androl 8 (Suppl. 1): 128
193. Henkel,R, Sturmhoefel,A, Schreiber,G, Hipler,UC, Zermann,DH, Menkveld,R (2006)
Comparison of three methods to evaluate human sperm morphology.
Asian J Androl 8 (Suppl. 1): 89-90
194. Menkveld,R, Henkel,R, Schüller,S, Hoppe,I, Starker,W (2006)
An investigation of the relationships between sperm morphology parameters, reactive
oxygen species production in semen and sperm DNA status.
Andrologie 16: 356
195. El-Garem,Y, Henkel,R, Menkveld,R, Schill,W-B (2006)
Relationship between human sperm morphology and acrosomal function.
Andrologie 16: 359
196. Mehnert,C, Fechner,C, Stalf,T, Tinneberg,H-R, Henkel,R, Schuppe,H-C (2006)
An in vitro model for epididymal sperm maturation.
Andrologie 16: 349
197. Menkveld,R, Henkel,R, Schüller,S, Hoppe,I and Starker,W (2007)
An investigation of the relationships between sperm morphology parameters, reactive
oxygen species production in semen and sperm DNA status.
Abstract book 19th World Congress on Fertility and Sterility, Durban, South Africa, 29.04.03.05.2007, p. 182
198. Henkel,R, Sturmhoefel,A, Hipler,UC, Zermann,DH, Schreiber,G and Menkveld,R (2007)
Human sperm morphology evaluated by means of Testsimplets® is not comparable with
standard procedures.
Abstract book 19th World Congress on Fertility and Sterility, Durban, South Africa, 29.04.03.05.2007; p. 65
199. Henkel,R (2007)
DNA based sperm assessment.
Abstract book 19th World Congress on Fertility and Sterility, Durban, South Africa, 29.04.03.05.2007; p. 22
200. Henkel,R, Ludwig,M, Schuppe,H-C, Diemer,T, Schill,W-B and Weidner,W (2007)
Chronic pelvic pain syndrome affects acrosome reaction in human spermatozoa.
Abstract book 51st Academic Yearday, Faculty of Health Sciences, Tygerberg Hospital and
University of Stellenbosch, 15.-16.08.2007, Stellenbosch, South Africa; p. 117
201. Hoogendijk,CF, Kruger,TF, Bouic,PJD, Henkel,R (2007)
The relationship between human sperm apoptosis and normal sperm morphology.
Abstract book 51st Academic Yearday, Faculty of Health Sciences, Tygerberg Hospital and
University of Stellenbosch, 15.-16.08.2007, Stellenbosch, South Africa; pp. 116-117
202. Menkveld,R, Henkel,R, Schüller,S, Hoppe,I and Starker,W (2007)
An investigation of the relationships between sperm morphology parameters, reactive
oxygen species production in spermatozoa and sperm DNA status.
Abstract book 51st Academic Yearday, Faculty of Health Sciences, Tygerberg Hospital and
University of Stellenbosch, 15.-16.08.2007, Stellenbosch, South Africa; p. 125
Prof. Ralf Henkel, PhD
42
203. Fransman,W, Menkveld,R, Kruger,T, Hoogendijk,C, Weitz,F, Henkel,R (2007)
In vitro effects of Typha capensis extracts on sperm motility and mitochondrial membrane
potential.
MRC Research Day, 18.10.2007, Parow, South Africa, Abstract book
204. Fransman,W, Menkveld,R, Kruger,T, Hoogendijk,C, Weitz,F, Henkel,R (2007)
In vitro effects of Typha capensis extracts on sperm motility and mitochondrial membrane
potential.
UWC Research Open Day, 01.-02.11.2007, Bellville, South Africa, Abstract book
205. Hipler,U, Henkel,R, Schreiber,G, Anita,S (2007)
Vergleich dreier Methoden zur morphologischen Evaluation menschlicher Spermatozoen.
J Reproduktionsmed Endokrinol 4: 280-281
206. Fransman,WO, Weitz,F, Menkveld,R, Kruger,TF, Henkel,R (2008)
In vitro effects of Typha capensis rhizome extract on sperm parameters.
11th Indigenous Plant Use Forum (IPUF), 07.-10.07.08, Graaff-Reinet, South Africa,
abstract book p 32
207. Henkel,R, Fransman,W, Hipler,UC, Schreiber,G, Weitz,F, Kruger,TF, Fisher,D,
Menkveld,R (2008)
Typha capensis extracts decrease human sperm ROS production and affect sperm
functions.
52nd Academic Yearday , Faculty of Health Sciences, Tygerberg Hospital and University of
Stellenbosch, 13.-14.08.08, Stellenbosch, South Africa, abstract book
208. Schreiber,G, Fransman,W, Hipler,UC, Weitz,F, Menkveld,R, Kruger,TF, Fisher,D,
Henkel,R (2008)
In vitro Effekte von Typha capensis Extrakten auf Spermienfunktionen und die Inhibierung
von reaktiven Sauerstoffspezies.
J Reproduktionsmed Endokrinol 4: 222-223
209. Fechner,J, Mehnert,C, Henkel,R, Schuppe,H-C (2008)
Primärkulturen boviner epididymaler Epithelzellen: Einfluß von Androgenen.
J Reproduktionsmed Endokrinol 4: 214-215
210. Mars,JA, Henkel,R, Fisher,D, Weitz,F (2008)
Determination of selenium in aqueous herbal extracts to be used fertility studies.
UWC Research Open Day, 28.-29.10.2008, Bellville, South Africa, abstract book
211. Erasmus,N, Weitz,F, Menkveld,R, Fisher,D, Henkel,R (2008)
The effects of Typha capensis extracts on acrosome reaction of human spermatozoa.
UWC Research Open Day, 28.-29.10.2008, Bellville, South Africa, abstract book
212. Amadi,SC, Moundipa,PF, Henkel,R, Monsees,TK (2008)
Effects of Basella alba extract on TM4 Sertoli cell function.
UWC Research Open Day, 28.-29.10.2008, Bellville, South Africa, abstract book
213. Henkel,R, Fransman,W, Hipler,UC, Schreiber,G, Weitz,F, Kruger,TF, Fisher,D,
Menkveld,R (2008)
Typha capensis extracts decrease ROS production and affect human sperm functions.
4th World Congress on Medicinal and Aromatic Plants, 9.-14.11.08, Cape Town, South
Africa, abstract book p. 75
Prof. Ralf Henkel, PhD
214. Mars,JA, Weitz,F, Fisher,D, Henkel,R (2008)
Determination of trace elements in aqueous herbal extracts to be used in male infertility.
4th World Congress on Medicinal and Aromatic Plants, 9.-14.11.08, Cape Town, South
Africa, supplementary abstract book p. 13
215. Fransman,W, Weitz,F, Fisher,D, Kruger, T, Menkveld,R, Henkel,R (2008)
In vitro effects of Typha capensis extracts on sperm parameters.
Int J Androl 31 (Suppl. 1): 15-16
216. Henkel,R, Fransman,W, Hipler,UC, Schreiber,G, Weitz,F, Kruger,TF, Fisher,D,
Menkveld,R (2009)
Typha capensis extracts decrease ROS production and affect human sperm functions.
9th International Congress of Andrology, 7.-10.03.2009, Barcelona, Spain (accepted)
217. Henkel,R, Hoogendijk,C, Bouic,PJD, Kruger,TF (2009)
TUNEL assay and SCSA determine different aspects of DNA damage.
9th International Congress of Andrology, 7.-10.03.2009, Barcelona, Spain (accepted)
43
Prof. Ralf Henkel, PhD
44
Poster:
1.
Dannhorn,D, Henkel,R und Kirchner,C (1988)
Synthese von Uteroglobin in der Blastozyste des Kaninchens? Nachweis durch
Autoradiographie und Immunzytochemie.
XIII. Veterinär-Humanmedizinische Gemeinschaftstagung Physiologie und Pathologie der
Fortpflanzung, 11.02.-12.02.88, Hannover
2.
Haidl,G, Henkel,R, Miska,W and Friedrich,K (1991)
Composition of human outer dense fibers and their significance to flagellar movement.
11th North American Testis Workshop, 24.04. - 27.04.91, Montreal, Canada
In: The Male Germ Cell: Spermatogonium to Fertilization
3.
Henkel,R, Friedrich,K, Haidl,G, Miska,W und Gips,H (1991)
Biochemische Untersuchungen der "outer dense fibers".
Dreiländertagung "Fertilität und Sterilität", 29.05. - 01.06.91, Goslar, Germany
4.
Fehl,P, Henkel,R, Kleinstein,J und Miska,W (1991)
Induktion der Akrosomreaktion durch humane Follikularflüssigkeit.
Dreiländertagung "Fertilität und Sterilität", 29.05. - 01.06.91, Goslar
5.
Haidl,G, and Henkel,R (1991)
Isolation and partial characterization of the outer dense fibers of human spermatozoa.
XIX. Jahrestagung der Arbeitsgemeinschaft Dermatologische Forschung,
15.11. - 17.11.91, Graz, Austria
6.
Henkel,R, Stalf,T, Miska,W, Gips,H and Schill,W-B (1992)
Isolation and partial characterization of the outer dense fiber proteins of human
spermatozoa.
XIV. World Congress on Fertility and Sterility, 22.11. - 27.11.92, Caracas, Venezuela
7.
Stalf,T, Henkel,R, Miska,W and Schill,W.-B. (1993)
Neue Erkenntnisse zu den Mantelfasern humaner Spermatozoen.
XVIII. Veterinär-Humanmedizinische Gemeinschaftstagung, 25.-26.02.93, Hannover
8.
Schill,W-B, Henkel,R, Müller,C, Miska,W and Gips,H (1993)
Evaluation of acrosomal reaction by low temperature in human spermatozoa is of
predictive value for IVF.
V. International Congress of Andrology 02.-06.05.93, Tokyo, Japan
9.
Henkel,R, Müller,C, Miska,W, Schill,W-B and Gips,H (1993)
Evaluation of acrosin activity by gelatinolysis is predictive for IVF.
VIII. World Congress on In Vitro Fertilization and Alternate Assisted Reproduction,
12.-15.09.93, Kyoto, Japan
10.
Henkel,R, Franken,DR, Schill,W-B and Lombard,CJ (1994)
The selective capacity of glass wool filtration for normal chromatin condensed human
spermatozoa: A possible therapeutic modality for male factor cases?
38. Academic Yearday, 04.08.94, University of Stellenbosch, South Africa
11.
Henkel,R, Müller,C, Miska,W, Schill,W-B, Kleinstein,J and Gips,H (1994)
Gelatinolysis: A simple assay to evaluate acrosin activity predicts fertilization in IVF
38. Academic Yearday, 04.08.94, University of Stellenbosch, South Africa
Prof. Ralf Henkel, PhD
45
12.
Henkel,R, Franken,DR, Schill,W-B and Lombard,CJ (1994)
The selective capacity of glass wool filtration for normal chromatin condensed human
spermatozoa: A possible therapeutic modality for male factor cases.
27th Congress of the South African Society of Obstetricians & Gynaecologists,
07.-11.08.94, Sun City, South Africa
13.
Miska,W, Finkenzeller,C, Geiger,R, Henkel,R and Schill,W-B (1994)
Zona binding assay using a bioluminescence-enhanced detection system.
8. International Symposium on Bioluminescence and Chemiluminescence,
05.-08.09.94, Cambridge, England
14.
Henkel,R, Kaskar,K, Schill,W-B and Franken,DR (1994)
Improvement of sperm binding to immature human oocytes by incubation in a chemically
defined medium.
22nd Annual Congress Physiology Society of Southern Africa, 05.-07.10.94, Stellenbosch,
South Africa
15.
Henkel,R, Franken,DR, Schill,W-B and Lombard,CJ (1994)
The selective capacity of glass wool filtration for normal chromatin condensed human
spermatozoa: A possible therapeutic modality for male factor cases?
22nd Annual Congress Physiology Society of Southern Africa, 05.-07.10.94, Stellenbosch,
South Africa
16.
Henkel,R, Franken,DR and Lombard,CJ (1994)
The selective capacity of glass wool filtration for normal chromatin condensed human
spermatozoa: A possible therapeutic modality for male factor cases?
50. Annual Meeting of the American Fertility Society, 05.-10.11.94, San Antonio, Texas,
USA
17.
Schaller,J, Henkel,R, Glander,H-J and Schill,W-B (1994)
Investigation of adhesion molecules and matrix proteins on human spermatozoa with
different binding and penetration properties in the HOP-test.
ADF, Würzburg, Germany
18.
Villegas,J, Miska,W, Stalf,T, Schalles,U, Henkel,R und Schill,W-B (1995)
Herstellung von monoklonalen Antikörpern gegen das Mantelfaser-Hauptprotein aus EberSpermatozoen.
28. Jahrestagung über Physiologie und Pathologie der Fortpflanzung, 09.-10.03.95, Gießen,
Germany
19.
Henkel,R, Cooper,S, Franken,DR, Kaskar,K and Schill,W-B (1995)
Structural changes of zona pellucida due to incubation in a chemically defined medium
cause improvement of sperm binding.
28. Jahrestagung über Physiologie und Pathologie der Fortpflanzung, 09.-10.03.95, Gießen,
Germany
20.
Henkel,R, Franken,DR, Kaskar,K, Schill,W-B and Kruger,TF (1995)
Inhibition of zona pellucida binding of human spermatozoa following exposure to
solubilized human zonae pellucidae is due to acrosomal loss.
28. Jahrestagung über Physiologie und Pathologie der Fortpflanzung, 09.-10.03.95, Gießen,
Germany
Prof. Ralf Henkel, PhD
46
21.
Schalles,UK, Villegas,J, Henkel,R und Miska,W (1995)
Immunelektronenmikroskopische Lokalisierung eines 30 kDa Polypeptids in den
Mantelfasern von Spermatozoen verschiedener Säugetierspezies.
28. Jahrestagung über Physiologie und Pathologie der Fortpflanzung, 09.-10.03.95, Gießen,
Germany
22.
Finkenzeller,Ch, Miska,W, Henkel,R und Schill,W-B (1995)
Entwicklung eines Zonabindungs-Assays mittels enzymverstärkter Biolumineszenz.
28. Jahrestagung über Physiologie und Pathologie der Fortpflanzung, 09.-10.03.95, Gießen,
Germany
23.
Henkel,R, Schaller,J, Glander,H-J and Schill,W-B (1995)
Investigation of adhesion molecules and matrix proteins on human sperm with different
binding and penetration properties in the HOP-test.
IX. World Congress on In Vitro Fertilization and Assisted Reproduction, 03.-07.04.95,
Vienna, Austria
24.
Henkel,R, Franken,DR, Lombard,CJ and Schill,W-B (1995)
The selective capacity of glass wool filtration for normal chromatin condensed human
spermatozoa: A possible therapeutic modality for male factor cases?
IX. World Congress on In Vitro Fertilization and Assisted Reproduction, 03.-07.04.95,
Vienna, Austria
25.
Henkel,R, Franken,DR, Schill,W-B and Habenicht,U-F (1995)
Dose- and time dependent induction of human sperm acrosome reaction by means of
solubilized zona pellucida proteins.
IX. World Congress on In Vitro Fertilization and Assisted Reproduction, 03.-07.04.95,
Vienna, Austria
26.
Schaller,J, Henkel,R, Glander,H-J and Schill,W-B (1995)
Adhäsionsmoleküle an humanen Spermatozoen mit unterschiedlichen Bindungs- und
Penetrationseigenschaften im HOP-Test.
38. Tagung der Deutschen Dermatologischen Gesellschaft, 29.04.-03.05.95, Berlin,
Germany
27.
Henkel,R, Schaller,J, Glander,H-J and Schill,W-B (1995)
Changes in expression of adhesion molecules on human sperm membrane after acrosome
reaction.
11th Annual Meeting of the ESHRE, 28.06.-01.07.95, Hamburg, Germany
28.
Stalf,T, Sanchez,R, Henkel,R, Khanaga,O, Turley,H, Schill,W-B and Gips,H (1995)
Comparison between two methods of sperm preparation for intracytoplasmic sperm
injection.
11th Annual Meeting of the ESHRE, 28.06.-01.07.95, Hamburg, Germany
29.
Baltes,P, Henkel,R and Miska,W (1995)
Further findings concerning the nature and function of the acrosome reaction-inducing
substance (ARIS) of human follicular fluid (hFF).
11th Annual Meeting of the ESHRE, 28.06.-01.07.95, Hamburg, Germany
30.
Schalles,UK, Villegas,J, Henkel,R and Miska,W (1995)
Evidence for an immunological difference among the medulla and cortex in mammalian
sperm tail outer dense fibres (ODF).
11th Annual Meeting of the ESHRE, 28.06.-01.07.95, Hamburg, Germany
Prof. Ralf Henkel, PhD
47
31.
Baltes,P, Sanchez,R, Schalles,UK, Villegas,J, Pena,P, Henkel,R, Turley,H and Miska,W
(1995)
Origin and nature of the acrosome reaction-inducing substance (ARIS) of human follicular
fluid (hFF).
International Symposium on Human Sperm Acrosome Reaction, 07.-09.09.95, Collioure,
France
32.
Henkel,R, Franken,DR, Maritz,JS, Schill,W-B and Habenicht,U-F (1995)
Studies on the kinetics of human sperm acrosome reaction. A mathematical model for
assessment.
International Symposium on Human Sperm Acrosome Reaction, 07.-09.09.95, Collioure,
France
33.
Franken,DR, Henkel,R, Kaskar,K and Habenicht,U-F (1995)
Inhibition of zona binding using solubilized human zona pellucida.
International Symposium on Human Sperm Acrosome Reaction, 07.-09.09.95, Collioure,
France
34.
Sanchez,R, Concha,M, Ichikawa,T, Henkel,R and Schill,W-B (1995)
Glass wool filtration reduces reactive oxygen species by elimination of leukocytes in
oligozoospermic patients.
XV. World Congress on Fertility and Sterility, 17.-22.09.95, Montpellier, France
35.
Franken,DR, Henkel,R, Kaskar,K and Schill,W-B (1995)
Chemical manipulation of immature human zona pellucida enhances sperm binding.
51. Meeting of the American Society for Reproductive Medicine, 07.-12.10.95, Seattle,
USA
36.
Henkel,R, Franken,DR, Schill,W-B and Habenicht,U-F (1995)
Studies on the kinetics of human sperm acrosome reaction.
51. Meeting of the American Society for Reproductive Medicine, 07.-12.10.95, Seattle,
USA
37.
Sánchez,R, Baltes,P, Peña,P, Villegas,J, Henkel,R and Miska,W (1996)
Immunohistochemical localization of a CBG-like SERPIN in human fallopian tubes at
various reproductive stages.
Immunhistochemische Lokalisierung eines CBG-ähnlichen SERPINs im menschlichen
Eileiter zu verschiedenen Zeiten des Zyklus.
29. Tagung über Physiologie und Pathologie der Fortpflanzung, 14-15.03.96, Leipzig,
Germany
38.
Henkel,R, Ichikawa,T, Sánchez,R, Miska,W and Schill,W-B (1996)
Effect of reactive oxygen species on human sperm motility.
Einfluß reaktiver Sauerstoffspezies auf die Motilität menschlicher Spermatozoen.
29. Tagung über Physiologie und Pathologie der Fortpflanzung, 14-15.03.96, Leipzig,
Germany
39.
Oeda,T, Ichikawa,T, Henkel,R, Nagai,A, Schill,W-B and Ohmori,H (1996)
N-Acetyl-L-Cystein scavenges reactive oxygen species (ROS) from human semen.
84th Meeting of the Japanese Urological Society, 03.-06.04.96, Okayama, Japan
Prof. Ralf Henkel, PhD
48
40.
Miska,W, Baltes,P, Sanchez,R, Henkel,R and Schill,W-B (1996)
Possible involvement of a CBG-like SERPIN in in vivo modulation of the acrosome
reaction.
International Symposium on the Chemistry and Biology of SERPINS, 13.04.-16.04.96,
Chapel Hill, USA
41.
Miska W, Monsees T, Finkenzeller Ch, Franken DR, Schill W-B, Henkel R (1996)
Evaluation of the bioluminescence-enhanced zona binding assay.
9th International Symposium on Bioluminescence and Chemiluminescence,
04.10.-08.10.1996, Woods Hole, MA, USA
42.
Miska,W, Schalles,U, Villegas,J and Henkel,R (1996)
Immunelectron microscopic studies on outer dense fibres.
The Fate of the Male Germ Cell, Symposium, 05.12.-06.12.96, Hamburg
43.
Baltes P, Sánchez R, Henkel R, Miska W (1996)
Putative role of a SERPIN in modulation of acrosome reaction
The Fate of the Male Germ Cell, 05.-06.12.1996, Hamburg
44.
Sánchez,R, Baltes,P, Peña,P, Villegas,J, Henkel,R, Schill,W-B, Miska,W (1997)
Presence of a CBG-like SERPIN in the female genital tract.
Workshop Molecular Andrology, 05.05.-06.05.97, Rauischholzhausen, Germany
45.
Henkel,R, Bittner,J, Weber,R, Schill,W-B and Miska,W (1997)
Determination of zinc in the human sperm flagellum and its correlation to motility.
Workshop Molecular Andrology, 05.05.-06.05.97, Rauischholzhausen, Germany
46.
Müller,C, Henkel,R, Stürzebecher,J, Hesse,S, Schill,W-B and Miska,W (1997)
Inhibition of human acrosin by low molecular mass inhibitors of the benzamidine-type.
Workshop Molecular Andrology, 05.05.-06.05.97, Rauischholzhausen, Germany
47.
Henkel,R, Bittner,J, Weber,R and Miska,W (1997)
The importance of flagellar zinc for human sperm motility.
VIth International Congress of Andrology, 25.-29.05.1997, Salzburg, Austria
48.
Oeda,T, Henkel,R, Nagai,A, Schill, W-B and Ohmori,H (1997)
N-Acetyl-L-Cysteine scavenges reactive oxygen species in human semen.
VIth International Congress of Andrology, 25.-29.05.1997, Salzburg, Austria
49.
Müller,C, Stürzebecher,J, Hesse,S, Schill,W-B, Henkel,R and Miska,W (1997)
Evaluation of benzamidine-type acrosin inhibitors.
VIth International Congress of Andrology, 25.-29.05.1997, Salzburg, Austria
50.
Miska,W, Baltes,P, Sánchez,R and Henkel,R (1997)
Characterization of the acrosome reaction-inducing substance of human follicular fluid.
VIth International Congress of Andrology, 25.-29.05.97, Salzburg, Austria
51.
Henkel,R, Monsees,T, Franken,DR and Miska,W (1997)
Development of a new zona pellucida binding assay.
41st Academic Yearday of the University of Stellenbosch, 20.08.97-21.08.97, Stellenbosch,
South Africa
52.
Henkel,R, Oeda,T, Ohmori,H and Schill,W-B (1997)
Reduzierung von reaktiven Sauerstoffspezies in menschlichem Ejakulat durch
N-Acetyl-L-Cystein.
IX. Jahrestagung der Deutschen Gesellschaft für Andrologie, 12.09.-13.09.97, Lübeck,
Germany
Prof. Ralf Henkel, PhD
49
53.
Monsees,TK, Henkel,R, Miska,W and Schill (1997)
Einfluß von Gossypol auf die sekretorische Funktion von Sertoli-Zellen.
IX. Jahrestagung der Deutschen Gesellschaft für Andrologie, 12.09.-13.09.97, Lübeck,
Germany
54.
Henkel,R, Monsees,T, Müller,C, Stalf,T, Franken,DR, Gips,H und Schill,W-B (1997)
Einsatz von erfolglos fertilisierten Eizellen im Hemizona Assay nach struktureller
Veränderung der Zona.
5. Dreiländertagung ‘Fertilität und Sterilität’, 18.09.-20.09.97, Schwäbisch-Gmünd,
Germany
55.
Müller,C, Stürzebecher,J, Hesse,S, Henkel,R, Schill,W-B und Miska,W (1997)
Charakterisierung verschiedener Akrosininhibitoren vom Benzamidin-Typ.
5. Dreiländertagung ‘Fertilität und Sterilität’, 18.09.-20.09.97, Schwäbisch-Gmünd,
Germany
56.
Huwe,P, Gesell,St, Diemer,Th, Henkel,R and Weidner,W (1998)
Influence of antibiotics on sperm motility in vitro.
14th Annual Meeting of the ESHRE, 21.-24.06.98, Gothenburg, Sweden
57.
Miska,W, Sánchez,R, Schill,W-B and Henkel,R (1998)
Sperm separation with SpermFertil® distinguishes between reactive oxygen species
generated by sperm or leukocytes.
10th Int. Symp. on Biolum. & Chemilum., 04.-08.09.1998, Bologna, Italy
58.
Müller,C, Henkel,R and Schill,W-B (1998)
The use of the hypoosmotic swelling test to predict fertilization in IVF.
16th World Congress on Fertility and Sterility, 03.-09.10.98, San Francisco, USA
59.
Sánchez,R, Peña,P, Henkel,R and Miska,W (1998)
Immunohistochemical localization of a CBG-like SERPIN in the human sperm acrosome.
16th World Congress on Fertility and Sterility, 03.-09.10.98, San Francisco, USA
60.
Henkel,R, Stalf,T, Seefeldt-Schmidt,B, Schill,W-B und Miska,W (1998)
Neue Untersuchungen zur Biochemie und Physiologie der Mantelfasern von
Säugerspermatozoen.
10. Jahrestagung der Deutschen Gesellschaft für Andrologie, 08.-10.10.98, Münster,
Germany
61.
Miska,W, Zwartenkot,E, Baltes,P, Linder,M, Schill,W-B und Henkel,R (1998)
Differentielle MALDI-ToF-MS-Analyse eines CBG-ähnlichen Proteins aus
unterschiedlichen Proben.
10. Jahrestagung der Deutschen Gesellschaft für Andrologie, 08.-10.10.98, Münster,
Germany
62.
Köhn,FM, Müller,C, Drescher,D, El Mulla,KF, Neukamm,C, Henkel,R, Habenicht,UF and
Schill,W-B (1998)
Effect of angiotensin converting enzyme (ACE) and angiotensins on human sperm
functions.
10. Jahrestagung der Deutschen Gesellschaft für Andrologie, 08.-10.10.98, Münster,
Germany
Prof. Ralf Henkel, PhD
50
63.
Huwe,P, Gesell,S, Diemer,T, Henkel,R und Weidner,W (1998)
Der Einfluß verschiedener Antibiotika auf die Motilität von humanen Spermatozoen in
vitro.
10. Jahrestagung der Deutschen Gesellschaft für Andrologie, 08.-10.10.98, Münster,
Germany
64.
Miska,W, Sánchez,R, Miska,G, Schill,W-B and Henkel,R (1999)
Differentiation of reactive oxygen species generated in sperm or leukocytes.
32. Jahrestagung Physiologie und Pathologie der Fortpflanzung, 18.-19.02.1999, Hannover,
Germany
65.
Henkel,R, Hanschke,A and Schill,W-B (1999)
Impairment of sperm motility by inflammatory parameters.
32. Jahrestagung Physiologie und Pathologie der Fortpflanzung, 18.-19.02.1999, Hannover,
Germany
66.
Henkel,R, Müller,C and Schill,W-B (1999)
Evaluation of the hypoosmotic swelling test for use in male factor infertility diagnosis.
32. Jahrestagung Physiologie und Pathologie der Fortpflanzung, 18.-19.02.1999, Hannover,
Germany
67.
Seefeldt-Schmidt,B, Henkel,R and Miska,W (1999)
Biochemical and immunological characterization of low molecular outer dense fiber
polypeptides of bull spermatozoa.
32. Jahrestagung Physiologie und Pathologie der Fortpflanzung, 18.-19.02.1999, Hannover,
Germany
68.
Sánchez,R, Peña,P, Hanschke,A, Schill,W-B and Henkel,R (1999)
Seasonal changes in human sperm chromatin condensation. First cases from the southern
hemisphere (Chile).
32. Jahrestagung Physiologie und Pathologie der Fortpflanzung, 18.-19.02.1999, Hannover,
Germany
69.
Miska,W, Zwartenkot,E, Baltes,P, Sánchez,R, Schill,W-B and Henkel,R (2000)
MALDI-ToF-MS analysis of a CBG-like protein.
33. Jahrestagung "Physiologie und Pathologie der Fortpflanzung", 17.-18.02.00, Berlin,
Germany
70.
Henkel,R, Baldauf,Ch, Bittner,J, Miska,W and Weidner,W (2000)
Elimination of zinc from sperm flagella during epididymal transit is important for motility.
16th Meeting of the ESHRE, 25.06.-28.06.2000, Bologna, Italy
71.
Villegas,J, Sánchez,R, Soto,L, Risopatrón,J, Bustos,L, Henkel,R (2000)
Metabolitos reactivos de oxigeno: Evaluación del efecto sobre el espermatozoide humano.
Informe preliminar.
Encuentro Iberoamericano de Andrología, 04.12.-07.12.2000, Cartagena de Indias, Chile
72.
Henkel,R, Defosse,K, Weißmann,N, Weidner,W, Schill,W-B, Miska,W (2001)
Flagellar zinc content and energy consumption of human spermatozoa.
26. Veterinär-Humanmedizinische Gemeinschaftstagung, 22.-23.02.2001, Gießen,
Germany
73.
Seefeldt-Schmidt,B, Henkel,R, Schill,W-B, Miska,W (2001)
Localization of a 11-kDa polypeptide in the outer dense fibers of bull spermatozoa.
26. Veterinär-Humanmedizinische Gemeinschaftstagung, 22.-23.02.2001, Gießen,
Germany
Prof. Ralf Henkel, PhD
51
74.
Miska W, Henkel R, Schill WB, Sánchez R (2001)
Possible in vivo modulation of human sperm acrosome reaction by a CBG-like protein.
VIIth International Congress of Andrology, 15.-19.6.2000, Montreal, Canada
75.
Menkveld,R, Schill,W-B, Henkel,R (2001)
Seasonal changes of chromatin condensation in human sperm.
45th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2001
76.
Henkel,R, Hajimohammad,M, Stalf,T, Menkveld,R, Schill,W-B, Kruger,T, Gips,H (2001)
Influence of DNA integrity on fertilisation and pregnancy.
45th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2001
77.
Henkel,R, Teichmann,U, Schill,W-B (2001)
Influence of different heavy metals on acrosome reaction and motility of human
spermatozoa.
45th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2001
78.
Menkveld,R, El-Garem,Y, Schill,W-B and Henkel,R (2001)
Relationship between acrosome size and acrosome reaction.
45th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2001
79.
Menkveld,R, Schill,W-B, Henkel,R (2001)
Seasonal changes of chromatin condensation in human sperm.
27th Congress of the SASOG, Sun City, South Africa, 19.-22.08.2001
80.
Menkveld,R, El-Garem,Y, Schill,W-B and Henkel,R (2001)
Relationship between acrosome size and acrosome reaction.
27th Congress of the SASOG, Sun City, South Africa, 19.-22.08.2001
81.
Henkel,R, Hajimohammad,M, Stalf, T, Menkveld,R, Schill,W-B, Kruger,TF and Gips,H
(2001)
DNA fragmentation of spermatozoa affects pregnancy but not fertilization rate.
XIII. Jahrestagung der Deutschen Gesellschaft für Andrologie, 06.-08.09.2001, Berlin,
Germany
82.
Henkel,R, Teichmann,U and Schill,W-B (2001)
Influence of different heavy metals on acrosome reaction and motility of human
spermatozoa.
XIII. Jahrestagung der Deutschen Gesellschaft für Andrologie, 06.-08.09.2001, Berlin,
Germany
83.
Henkel,R, Menkveld,R, El-Garem,Y and Schill,W-B (2001)
Acrosomal function is dependent on the size of the acrosome.
XIII. Jahrestagung der Deutschen Gesellschaft für Andrologie, 06.-08.09.2001, Berlin,
Germany
84.
Wroblewski,N, Miska,W, Schill,W-B and Henkel,R (2001)
Dose-dependent effect of different chelators on motility of human spermatozoa.
XIII. Jahrestagung der Deutschen Gesellschaft für Andrologie, 06.-08.09.2001, Berlin,
Germany
85.
Miska,W, Peña,P, Vásquez,B, Vasconcellos,A, Henkel,R and Sánchez,R (2001)
Detection and localization of a transcortin-like substance in ovarian connectin tissue.
XIII. Jahrestagung der Deutschen Gesellschaft für Andrologie, 06.-08.09.2001, Berlin,
Germany
Prof. Ralf Henkel, PhD
52
86.
Henkel,R, Hajimohammad,C, Stalf,T, Hoogendijk,C, Menkveld,R, Schill,W-B and
Kruger,TF (2001)
Importance to evaluate sperm DNA fragmentation prior to IVF.
Jahrestagung der Deutschen Gesellschaft für Reproduktionsmedizin, 16.-17.11.2001,
Gießen, Germany
87.
Wroblewski,N, Miska,W, Schill, W-B and Henkel,R (2001)
Qualitative changes in human sperm motility pattern following administration of chelators.
Jahrestagung der Deutschen Gesellschaft für Reproduktionsmedizin, 16.-17.11.2001,
Gießen, Germany
88.
Miska,W, Peña,P, Vasconcellos,A, Vásquez,B, Henkel,R, Sánchez,R (2001)
Immunocytochemical localization of transcortin in human ovarian connective tissue.
Jahrestagung der Deutschen Gesellschaft für Reproduktionsmedizin, 16.-17.11.2001,
Gießen, Germany
89.
Villegas,J, Catalán,S, Soto,L, Henkel,R and Sánchez,R (2001)
Reactive oxygen species (ROS) induce reversible capacitation in human spermatozoa.
17th World Congress on Fertility and Sterility, 25.-30.11.2001, Melbourne, Australia
90.
Henkel,R, El-Garem,Y, Schill,W-B and Menkveld,R (2002)
Relationship between acrosomal function and morphology.
35. Jahrestagung zur Physiologie und Pathologie der Fortpflanzung, 14.-15.02.2002,
Leipzig, Germany
91.
Seefeldt-Schmidt,B, Henkel,R, Schill,W-B and Miska,W (2002)
Localication of a new polypeptide in mammalian outer dense fibres.
International Workshop “New Trends in Molecular Andrology”, 03.-04.05.2002,
Rauischholzhausen, Germany
92.
Baldauf,C, Miska,W, Weidner,W, Schill,W-B and Henkel,R (2002)
Principal cells in the cauda epiddymis resorb zinc eliminated from spermatozoa.
International Workshop “New Trends in Molecular Andrology”, 03.-04.05.2002,
Rauischholzhausen, Germany
93.
Henkel,R, Baldauf,C, Miska,W, Weidner,W and Schill,W-B (2002)
Zinc eliminated from bull spermatozoa is taken up by cauda epididymis and vas deferens.
Third International Conference on the Epididymis, 29.05.-01.06.2002, Charlottesville,
Virginia, USA
94.
Monsees,TK, Kos,P, Schill,W-B and Henkel,R (2002)
Identification of protease activities in testicular rat peritubular cells.
14th Annual Meeting of the German Society of Andrology, 05.-07.09.2002, Jena, Germany
95.
Slavov,M, Schroeder-Printzen,I, Henkel,R, Steger,K, Bergmann,M, Failing,K and
Weidner,W (2002)
Determination of chromatin condensation and nuclear proteins in testicular and epididymal
spermatozoa and round spermatids in a standardized rabbit of obstructive azoospermia.
14th Annual Meeting of the German Society of Andrology, 05.-07.09.2002, Jena, Germany
96.
Seefeldt-Schmidt,B, Henkel,R, Schill,W-B and Miska,W (2002)
New findings on the cortical structure of mammalian outer dense fibres.
9th International Symposium on Spermatology, 06.-11.10.2002; Cape Town, South Africa
Prof. Ralf Henkel, PhD
53
97.
Stalf,T, Hajimohammad,M, Hoogendijk,C, Mehnert,C, Menkveld,R, Gips,H, Schill,W-B,
Kruger,TF and Henkel,R (2003)
IVF outcome is related to sperm DNA fragmentation but not to apoptosis.
19th Annual Meeting of the ESHRE, 29.06.-02.07.2003, Madrid, Spain
98.
Henkel,R, Baldauf,C, Eickhoff,R, Koyro,H-W and Meinhardt,A (2003)
Influence of the macrophage migration inhibitory factor on sperm zinc content.
Joint Annual Meeting of the Deutsche Gesellschaft für Andrologie and Deutsche
Gesellschaft für Reproduktionsmedizin, 11.-13.09.2003, München, Germany
99.
Mehnert,C, Stalf,T, Kierspel,E, Menkveld,R, Kruger,TF, Tinneberg,H-R, Schill,W-B and
Henkel,R (2004)
Effect of intrinsic and extrinsic ROS on sperm functions.
20th Annual Meeting of the ESHRE, 27.-30.06.2004, Berlin, Germany
100. Hoogendijk,CF, Kruger,TF, Lombard,C and Henkel,R (2004)
Correlation of human sperm DNA fragmentation and apoptosis rate with normal sperm
morphology.
48th Academic Yearday, University of Stellenbosch, 22.-23.08.2004, Stellenbosch, South
Africa
101. Henkel,R, Mehnert,C, Hendrischk,AK, Stalf,T, Tinneberg,HR and Schill,W-B (2004)
Culture of bovine epididymal epithelial cells in a protein-free cell culture medium.
3rd European Congress of Andrology together with the 16th Congress of German Society of
Andrology, 11.-14.09.2004, Münster, Germany
102. Mehnert,C, Schuppe,H-C, Stalf,T, Henkel,R, Weidner,W, Tinneberg,H-R and Schill,W-B
(2004)
Importance of sperm origin for the outcome of ICSI.
3rd European Congress of Andrology together with the 16th Congress of German Society of
Andrology, 11.-14.09.2004, Münster, Germany
103. Slavov,M, Diemer,T, Schroeder-Printzen,I, Henkel,R, Steger,K, Bergmann,M and
Weidner,W (2004)
Chromatin condensation and expression of nuclear proteins in spermatozoa and round
spermatids in vasectomized rabbits.
3rd European Congress of Andrology together with the 16th Congress of German Society of
Andrology, 11.-14.09.2004, Münster, Germany
104. Henkel,R, Maaß,G, Schuppe,H-C, Jung,A, Schubert,J, Schill,W-B (2005)
High flagellar zinc concentration is responsible for decreased sperm otility in ageing men.
8th International Congress of Andrology, 12.-16.06.2005, Seoul, Korea
105. Henkel,R, Maaß,G, Schuppe,H-C, Jung,A, Schubert,J, Schill,W-B (2005)
Seasonal changes of α-glucosidase activity in human semen.
8th International Congress of Andrology, 12.-16.06.2005, Seoul, Korea
106. Henkel,R, Zermann,DH, Maaß,G, Schuppe,H-C, Jung,A, Schubert,J, Schill,W-B (2005)
Seasonal changes of α-glucosidase activity in human semen.
57. Congress of the German Society for Urology, Düsseldorf, Germany, 21.-24.09.2005
107. Bittorf,K, Henkel,R, Hayatpour,J, Monsees,TK (2005)
Effect of xenoestrogens on primary rat Sertoli cell functions.
International Workshop “"Molecular Andrology: Testicular Pathology - Androgen Action Sperm Function", 07.-09.10.2005, Gießen, Germany
Prof. Ralf Henkel, PhD
54
108. Hinkel,S, Hayatpour,J, Henkel,R, Monsees,TK (2005)
Influence of xenoestrogens on rat Leydig cell functions.
International Workshop “"Molecular Andrology: Testicular Pathology - Androgen Action Sperm Function", 07.-09.10.2005, Gießen, Germany
109. Jung,A, Schuppe,H-C, Maaß,G, Haidl,G, Schill,W-B, Henkel,R (2005)
Age-related changes in seminal PMN-elastase in men with asymptomatic inflammation of
the genital tract.
International Workshop “"Molecular Andrology: Testicular Pathology - Androgen Action Sperm Function", 07.-09.10.2005, Gießen, Germany
110. Schuppe,H-C, Maaß,G, Jung,A, Schubert,J, Schill,W-B, Henkel,R (2005)
Jahreszeitliche Schwankungen der α-Glukosidaseaktivität im menschlichen Ejakulat.
1. DVR-Kongreß, 07.-10.12.05, Münster, Germany
111. Schuppe,H-C, Maaß,G, Jung,A, Haidl,G, Schill,W-B, Henkel,R (2005)
Altersabhängiger Anstieg der PMN-Elastase im Seminlaplasma bei Männern mit stillen
asymptomatischen Entzündungsreaktionen des Genitaltraktes.
1. DVR-Kongreß, 07.-10.12.05, Münster, Germany
112. Henkel,R, Schuppe,H-C, Maaß,G, Jung,A, Schill,W-B (2005)
Molekulare Ursachen für die abnehmende Spermienmotilität bei älteren Männern.
1. DVR-Kongreß, 07.-10.12.05, Münster, Germany
113. Ludwig,M, Schuppe,H-C, Diemer,T, Schill,W-B, Weidner,W, Henkel,R (2005)
Chronisches Beckenschmerzsyndrom/chronische Prostatitis beeinträchtigen die
Akrosomreaktion bei menschlichen Spermatozoen.
1. DVR-Kongreß, 07.-10.12.05, Münster, Germany
114. Ludwig,M, Diemer,T, Schuppe,HC, Schill,W-B, Weidner,W, Henkel,R (2006)
Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) influences acrosome function
in spermatozoa.
21st Annual Congress of the European Association of Urology, 05.-08.04.2006, Paris,
France
115. Ludwig,M, Diemer,T, Schuppe,HC, Schill,W-B, Weidner,W, Henkel,R (2006)
Chronic pelvic pain syndrome/chronic prostatitis (CPPS/CP) perturbs acrosome reaction in
human spermatozoa.
Annual Congress of the American Urological Association, 20.-25.05.2006, Atlanta, USA
116. Henkel,R, Sturmhoefel,A, Schreiber,G, Hipler,UC, Zermann,DH, Menkveld,R (2006)
Comparison of three methods to evaluate human sperm morphology.
50th Academic Yearday, Faculty of Health Sciences, Tygerberg Hospital and University of
Stellenbosch, 16.-17.08.2006, Stellenbosch, South Africa
117. Hoogendijk CF, Kruger TF, Henkel R (2006)
Correlation of human sperm DNA fragmentation and apoptosis rate with normal sperm
morphology .
50th Academic Yearday, Faculty of Health Sciences, Tygerberg Hospital and University of
Stellenbosch, 16.-17.08.2006, Stellenbosch, South Africa
118. Mehnert,C, Fechner,C, Stalf,T, Tinneberg,H-R, Henkel,R, Schuppe,H-C (2006)
Ein in-vitro-Modell für die epididymale Spermienreifung.
18. Annual Congress of the German Society of Andrology, 07.-09.09.2006, Düsseldorf,
Germany
Prof. Ralf Henkel, PhD
55
119. Henkel,R, Schuppe,H-C, Maaβ,G, Jung,A, Haidl,G, Schill,W-B (2006)
Age-related changes in seminal PMN-elastase in men with asymptomatic inflammation of
the genital tract.
2nd Asia-Pacific Forum on Andrology, 26.-30.10.2006, Shanghai, China
120. Henkel,R, Maaß,G, Schuppe,H-C, Jung,A, Schill,W-B (2006)
Molecular causes for declining sperm motility in elderly men.
2nd Asia-Pacific Forum on Andrology, 26.-30.10.2006, Shanghai, China
121. El-Garem,Y, Henkel,R, Schill,W-B, Menkveld,R (2006)
Relationship between human sperm morphology and acrosomal function.
4th European Congress of Andrology, 07.-10.12.2006, Toulouse, France
122. Mehnert,C, Fechner,C, Stalf,T, Tinneberg,H-R, Henkel,R, Schuppe,H-C (2006)
An in vitro model for epididymal sperm maturation.
4th European Congress of Andrology, 07.-10.12.2006, Toulouse, France
123. Menkveld,R, Henkel,R, Schüller,S, Hoppe,I, Starker,W (2006)
An investigation of the relationships between sperm morphology parameters, reactive
oxygen species production in semen and sperm DNA status.
4th European Congress of Andrology, 07.-10.12.2006, Toulouse, France
124. Menkveld,R, Henkel,R, Schüller,S, Hoppe,I and Starker,W (2007)
An investigation of the relationships between sperm morphology parameters, reactive
oxygen species production in semen and sperm DNA status.
19th World Congress on Fertility and Sterility, 29.04.-03.05.2007, Durban, South Africa
125. Menkveld,R, Henkel,R, Schüller,S, Hoppe,I and Starker,W (2007)
An investigation of the relationships between sperm morphology parameters, reactive
oxygen species production in spermatozoa and sperm DNA status.
51st Academic Yearday, Faculty of Health Sciences, Tygerberg Hospital and University of
Stellenbosch, 15.-16.08.2007, Stellenbosch, South Africa
126. Fransman,W, Menkveld,R, Kruger,T, Hoogendijk,C, Weitz,F, Henkel,R (2007)
In vitro effects of Typha capensis extracts on sperm motility and mitochondrial membrane
potential.
MRC Research Day, 18.10.2007, Parow, South Africa
127. Fransman,W, Menkveld,R, Kruger,T, Hoogendijk,C, Weitz,F, Henkel,R (2007)
In vitro effects of Typha capensis extracts on sperm motility and mitochondrial membrane
potential.
UWC Research Open Day, 01.-02.11.2007, Bellville, South Africa
128. Hipler,U, Henkel,R, Schreiber,G, Anita,S (2007)
Vergleich dreier Methoden zur morphologischen Evaluation menschlicher Spermatozoen.
2. DVR-Kongreß 28.11.-01.12.2007, Bonn, Germany
129. Henkel,R, Fransman,W, Hipler,UC, Schreiber,G, Weitz,F, Kruger,TF, Fisher,D,
Menkveld,R (2008)
Typha capensis extracts decrease human sperm ROS production and affect sperm
functions.
52nd Academic Yearday , Faculty of Health Sciences, Tygerberg Hospital and University of
Stellenbosch, 13.-14.08.08, Stellenbosch, South Africa
Prof. Ralf Henkel, PhD
56
130. Fechner,J, Mehnert,C, Henkel,R, Schuppe,H-C (2008)
Primärkulturen boviner epididymaler Epithelzellen: Einfluß von Androgenen.
20th Annual Congress of the German Society of Andrology, 11.-13.09.08, Halle/S.,
Germany
131. Schreiber,G, Fransman,W, Hipler,UC, Weitz,F, Menkveld,R, Kruger,TF, Fisher,D,
Henkel,R (2008)
In vitro Effekte von Typha capensis Extrakten auf Spermienfunktionen und die Inhibierung
von reaktiven Sauerstoffspezies.
20th Annual Congress of the German Society of Andrology, 11.-13.09.08, Halle/S.,
Germany
132. Mars,JA, Henkel,R, Fisher,D, Weitz,F (2008)
Determination of selenium in aqueous herbal extracts to be used fertility studies.
UWC Research Open Day, 28.-29.10.2008, Bellville, South Africa
133. Erasmus,N, Weitz,F, Menkveld,R, Fisher,D, Henkel,R (2008)
The effects of Typha capensis extracts on acrosome reaction of human spermatozoa.
UWC Research Open Day, 28.-29.10.2008, Bellville, South Africa
134. Amadi,SC, Moundipa,PF, Henkel,R, Monsees,TK (2008)
Effects of Basella alba extract on TM4 Sertoli cell function.
UWC Research Open Day, 28.-29.10.2008, Bellville, South Africa
Prof. Ralf Henkel, PhD
57
Lectures:
1.
Henkel,R, Dannhorn,DR, Petzold,U und Kirchner,C (1989)
Polyvinylpyrrolidon als Proteinersatz in der in-vitro Kultur von Kaninchenblastocysten.
Dreiländertagung "Fertilität und Sterilität" vom 07.12.-09.12.89 in Salzburg, Austria
2.
Henkel,R (1990)
Proteinsekretion von Kaninchenblastocysten.
Vortrag im reproduktionsbiologischen Kolloquium der Hautklinik Gießen am 04.12.90
3.
Haidl,G, Hornik,S und Henkel,R (1991)
Korrelation der gestörten Chromatinkondensation mit dem Akrosingehalt und der
Fertilitätsrate.
X. Andrologentagung der Sektion Andrologie der Gesellschaft für Dermatologie, Jena, 14.16.02.91
4.
Henkel,R, Haidl,G, Friedrich,K, Miska,W und Gips,H (1991)
Charakterisierung der Mantelfasern menschlicher Spermatozoen.
XVI. Veterinär-Humanmedizinische Gemeinschaftstagung Physiologie und Pathologie der
Fortpflanzung, Leipzig, 21.-22.02.91
5.
Henkel,R, Müller,C, Hornik,S, Haidl,G, Weißmann,N, Schill,W-B und Gips,H (1991)
Zusammenhang zwischen Akrosinaktivität, Chromatinkondensation, akrosomaler Reaktion
und Befruchtungsfähigkeit menschlicher Spermatozoen im IVF-Programm.
Dreiländertagung "Fertilität und Sterilität", 29.05. - 01.06.91, Goslar
6.
Haidl,G und Henkel,R (1991)
Neue Aspekte zu einer auf defekten Mantelfasern beruhenden Flagellumstörung.
Dreiländertagung "Fertilität und Sterilität", 29.05. - 01.06.91, Goslar
7.
Henkel,R (1991)
The prognostic value of some functional parameters of sperm for fertilization capacity in
IVF.
Invited lecture at the PIVET Medical Centre, 13.09.91, Perth, Australia
8.
Henkel,R (1991)
Die Bedeutung andrologischer Funktionsdiagnostik für die IVF.
Vortag am 13.11.91; Fortbildungsveranstaltung für niedergelassene Urologen,
Gynäkologen und Dermatologen
9.
Henkel,R (1992)
Spermatozoenmotilität und -funktionsparameter: Relevanz für Diagnostik und IVF.
Eingeladener Vortrag im Reproduktionsbiologischen Kolloquium des Zentrums für
Dermatologie und Andrologie der JLU, Gießen, 14.01.92
10.
Henkel,R (1992)
Bedeutung akrosomaler Parameter bei der IVF.
Symposium am Zentrum für Dermatologie und Andrologie JLU Gießen
Zentrum für Dermatologie und Andrologie der JLU Gießen, 14.02.92
11.
Henkel,R (1992)
Proteinchemische Charakterisierung der ODF
Symposium am Zentrum für Dermatologie und Andrologie JLU Gießen
Zentrum für Dermatologie und Andrologie der JLU Gießen, 14.02.92
Prof. Ralf Henkel, PhD
58
12.
Henkel,R, Stalf,T, Miska,W und Gips,H (1992)
Weitere proteinchemische Untersuchungen der "Outer Dense Fibers" humaner
Spermatozoen.
XVII. Veterinär-Humanmedizinische Gemeinschaftstagung vom 05.03.-06.03.92,
München
13.
Henkel,R (1992)
Functional parameters of spermatozoa and fertilization in IVF.
Invited lecture at the Department of Obstetrics and Gynaecology, Tygerberg Hospital,
13.10.92, Tygerberg, South Africa
14.
Henkel,R (1992)
Diagnostische Möglichkeiten von Zonabindungsassays und Mikromanipulation.
Vortrag im Rahmen der IVF-Fortbildung am Zentrum für Frauenheilkunde und
Geburtshilfe der JLU Gießen am 10.11.92
15.
Henkel,R, Müller,C, Miska,W and Gips,H (1992)
The acrosome reaction is a predictive parameter in rating the fertilizing capacity of human
spermatozoa for IVF.
XIV. World Congress on Fertility and Sterility, 22.11. - 27.11.92, Caracas, Venezuela
16.
Schill,W-B, Henkel,R and Miska,W (1992)
Biotests of sperm function.
XIV. World Congress on Fertility and Sterility, 22.11. - 27.11.92, Caracas, Venezuela
17.
Miska,W, Henkel,R und Stalf,T (1993)
Neue Aspekte zur Physiologie der Mantelfasern humaner Spermatozoen.
Dreiländertagung "Fertilität und Sterilität" 06.-08.05.93, Lugano, Switzerland
18.
Henkel,R. (1993)
Einfluß verschiedener Separationstechniken auf die Funktionen von menschlichen
Spermatozoen.
37. Tagung der Deutschen Dermatologischen Gesellschaft, 14.-18.07.93, Düsseldorf
19.
Henkel,R (1993)
Sperma-Aufbereitungstechniken als Vorbedingung für die Assistierte Reproduktion.
Jahrestagung der Deutschen Gesellschaft für Andrologie, 24.-25.09.93, Hamburg
20.
Henkel,R (1993)
Methoden der Spermaaufbereitung für die assistierte Reproduktion.
Eingeladener Vortrag auf einer Fortbildungsveranstaltung für niedergelassene Gynäkologen
am Zentrum für Dermatologie und Andrologie, 27.11.93
21.
Henkel,R (1994)
The selective capacity of glass wool filtration for normal chromatin condensed human
spermatozoa: A possible therapeutic modality for male factor cases?
Invited lecture at the Dept. Obstet. Gynaecol., Reproductive Biology Unit, Tygerberg
Hospital, Tygerberg, South Africa, 08.03.94
22.
Henkel,R (1994)
Influence of different sperm separation techniques on function of human spermatozoa.
Invited lecture at the Dept. Obstet. Gynaecol., Reproductive Biology Unit, Tygerberg
Hospital, Tygerberg, South Africa, 15.03.94
Prof. Ralf Henkel, PhD
59
23.
Henkel,R (1994)
The acrosome reaction is a predictive parameter in rating the fertilizing capacity of human
spermatozoa for IVF.
Invited lecture at the Dept. Obstet. Gynaecol., Reproductive Biology Unit, Tygerberg
Hospital, Tygerberg, South Africa, 29.03.94
24.
Henkel,R (1994)
Improvement of sperm binding to immature human zonae pellucida after incubation in a
chemically defined medium.
Invited lecture at the Dept. Obstet. Gynaecol., Reproductive Biology Unit, Tygerberg
Hospital, Tygerberg, South Africa, 17.05.94
25.
Henkel,R (1994)
Evaluation of acrosin activity by gelatinolysis is predictive for IVF.
Invited lecture at the Dept. Obstet. Gynaecol., Reproductive Biology Unit, Tygerberg
Hospital, Tygerberg, South Africa, 24.05.94
26.
Henkel,R (1994)
Outer dense fibers of human spermatozoa. -Partial characterization and possible
physiological functionsInvited lecture at the Dept. Obstet. Gynaecol., Reproductive Biology Unit, Tygerberg
Hospital, Tygerberg, South Africa, 07.06.94
27.
Schill,W-B, Henkel,R, Sanchez,R, Khanaga,O, Turley,H, Haidl,G and Gips,H (1994)
Sperm function tests: Do they have any predictive value?
ESHRE 10th Annual Meeting, 25.-29.06.94, Brussels, Belgium
28.
Henkel,R (1994)
Role of human sperm acrosome reaction for fertilization.
Invited lecture at the Dept. Obstet. Gynaecol., Infertility Clinic, University of the Orange
Free State, Bloemfontein, South Africa, 28.06.94
29.
Henkel,R, Kaskar,K, Schill,W-B and Franken,DR (1994)
Improvements of sperm binding to immature human oocytes by incubation in a chemically
defined medium.
27th Congress of the South African Society of Obstetricians & Gynaecologists,
07.-11.08.94, Sun City, South Africa
30.
Kruger,TF, Henkel,R and Oehninger,SC (1994)
Prediction of sperm fertilizing potential.
27th Congress of the South African Society of Obstetricians & Gynaecologists,
07.-11.08.94, Sun City, South Africa
31.
Henkel,R (1994)
Organisation of a typical Andrology laboratory in Germany.
Invited lecture at the Dept. Obstet. Gynaecol., Reproductive Biology Unit, Tygerberg
Hospital, Tygerberg, South Africa, 23.08.94
32.
Sánchez,R, Miska,W, Concha,M, Henkel,R und Schill,W-B (1994)
Differentialdiagnose reaktiver Sauerstoffspezies mittels Glaswollfiltration bei Patienten mit
Oligozoospermie.
II. Internationales Grazer Andrologie Symposium, 08.-10.09.94, Graz, Austria
Prof. Ralf Henkel, PhD
60
33.
Henkel,R (1994)
Development of a highly sensitive bioluminescence enhanced assay to detect zona
pellucida proteins.
Invited lecture at the Dept. Obstet. Gynaecol., Reproductive Biology Unit, Tygerberg
Hospital, Tygerberg, South Africa, 06.09.94
34.
Franken,DR, Henkel,R and Kaskar,K (1994)
Sperm-egg interaction
Invited lecture at the Jones Institute for Reproductive Medicine, Dept. Obstet. and
Gynaecol., Norfolk, Virginia, USA, 03.11.94
35.
Henkel,R (1995)
Functional sperm parameters.
Site visit of a committee of the European Academy of Andrology, 24.03.95, Gießen
36.
Henkel,R, Cooper,S, Franken,DR, Kaskar,K, Schill,W-B and Habenicht,U-F (1995)
Structural changes of zona pellucida due to incubation in a chemically defined medium
cause improvement of sperm binding.
IX. World Congress on In Vitro Fertilization and Assisted Reproduction, 03.-07.04.95,
Vienna, Austria
37.
Franken,DR, Henkel,R, Kaskar,K, Schill,W-B and Habenicht,U-F (1995)
The influence of solubilized human zona pellucida on zona binding and acrosome reaction
of human sperm.
9th Biennial Congress of the Southern African Society of Reproductive Biology,
07.-08.06.95
38.
Franken,DR, Henkel,R, Kaskar,K and Schill,W-B (1995)
The importance of the human acrosome during zona pellucida binding.
9th Biennial Congress of the Southern African Society of Reproductive Biology,
07.-08.06.95
39.
Henkel,R (1995)
Einfluß von Zona pellucida auf Spermatozoen-Funktionsparameter.
Vortrag im Rahmen des Reproduktionsbiologischen Kolloquiums am Zentrum für
Dermatologie und Andrologie der JLU Gießen, 14.06.95
40.
Henkel,R, Cooper,S, Kaskar,K, Schill,W-B, Franken,DR and Habenicht,U-F (1995)
Improvement of sperm binding due to structural changes of human zona pellucida.
11th Annual Meeting of the ESHRE, 28.06.-01.07.95, Hamburg, Germany
41.
Henkel,R (1995)
Einführung in die Methoden der Spermatozoenseparation.
Eingeladener Vortrag auf einer Fortbildungsveranstaltung für niedergelassene Gynäkologen
am Zentrum für Dermatologie und Andrologie der JLU, 26.08.95, Gießen
42.
Köhn,FM, Henkel,R, El-Mulla,KF and Schill,W-B (1995)
Physiopathology of acrosome dysfunctions.
International Symposium on Human Sperm Acrosome Reaction, 07.-09.09.95, Collioure,
France
43.
Schill,W-B, Köhn,F-M, Henkel,R and Haidl,G (1995)
Biochemical aspects of semen analysis.
XV. World Congress on Fertility and Sterility, 17.-22.09.95, Montpellier, France
Prof. Ralf Henkel, PhD
61
44.
Henkel,R (1995)
Spermatozoenfunktionstests und Prädiktion der Ergebnisse assistierter Reproduktion.
Tagung der Deutschen Gesellschaft für Andrologie, 29.-30.09.95, Marburg, Germany
45.
Bittner,J, Henkel,R, Weber,R, Hüther,F, Schill,W-B und Miska,W (1995)
Entwicklung einer Methode zur getrennten Bestimmung von Zink in Kopf und Flagellum
menschlicher Spermatozoen.
Dreiländertagung Fertilität und Sterilität, 12.-14.10.1995, Innsbruck, Austria
46.
Franken,DR, Henkel,R, Kaskar,K and Habenicht,U-F (1995)
Inhibition of zona binding using solubilized human zona pellucida: Defining bio-assay
conditions to evaluate zona pellucida binding characteristics.
Int. Symposium, Andrology in the Nineties; 18.-21.10.95, Genk, Belgium
47.
Franken,DR, Henkel,R, Cooper,S, Kaskar,K and Schill,W-B (1995)
Chemical manipulation of immature human zona pellucida enhances sperm binding.
Int. Symposium, Andrology in the Nineties; 18.-21.10.95, Genk, Belgium
48.
Oeda,T, Henkel,R, Schill,W-B and Ohmori,H (1996)
Scavenging effect of N-Acetyl-L-cysteine (ACC) for reactive oxygen species (ROS) from
human semen. A possible therapy in male factor infertility?
Reduzierung von reaktiven Sauerstoffspezies (ROS) in menschlichem Ejakulat durch
N-Acetyl-L-Cystein (ACC). Eine mögliche Therapie für die männliche Infertilität?
29. Tagung über Physiologie und Pathologie der Fortpflanzung, 14-15.03.96, Leipzig,
Germany
49.
Miska,W, Baltes,P, Sanchez,R, Henkel,R and Schill,W-B (1996)
Possible involvement of a CBG-like SERPIN in in vivo modulation of the acrosome
reaction.
International Symposium on the Chemistry and Biology of SERPINS, 13.-16.04.96, Chapel
Hill, USA
50.
Henkel,R, Finkenzeller,Ch, Monsees,T, Franken,DR, Schill,W-B and Miska,W (1996)
Development of a highly sensitive, bioluminescence enhanced zona binding assay.
12th Annual Meeting of the ESHRE, 30.06.-03.07.96, Maastricht, Netherlands
51.
Oeda,T, Henkel,R, Ichikawa,T, Nagai,A, Ozawa,H, Akiyama,H, Akiyama,M,
Schill,W-B and Ohmori,H (1996)
In vitro effect of N-acetyl-L-cysteine on reactive oxygen species in human semen.
15th Annual Meeting of the Japanese Society of Andrology, 19.-20.07.96, Kurashiki, Japan
52.
Miska,W, Monsees,T, Finkenzeller,Ch, Franken,DR, Schill,W-B and Henkel,R (1996)
Evaluation of the bioluminescence-enhanced zona binding assay.
9th Int. Symp. on Biolum. & Chemilum., 04.-08.10.96, Woods Hole, USA
53.
Henkel,R (1996)
Spermaaufbereitung bei urogenitaler Infektion.
Invited lecture at the 3rd Gießener Andrologisches Symposium, 16.11.96, Gießen, Germany
54.
Henkel,R (1997)
Die Bedeutung funktioneller Parameter von Spermatozoen für den Fertilisationsprozeß.
Invited lecture at the Institute of Histology and Embryology, University of Graz, Graz,
Austria, 16.01.97
Prof. Ralf Henkel, PhD
62
55.
Köhn,FM, Henkel,R, Eberl,M and Schill,W-B (1997)
Inhibition of angiotensin converting enzyme (ACE) by captopril reduces human sperm
binding to the plasma membrane of zona-free hamster oocytes.
30. Jahrestagung über Physiologie und Pathologie der Fortpflanzung/22. VeterinärHumanmedizinische Gemeinschaftstagung 20.-21.02.1997, Vienna, Austria
56.
Henkel,R (1997)
Zona pellucida as physiological trigger for the induction of acrosome reaction.
Invited lecture at the Workshop Molecular Andrology, 05.05.-06.05.97,
Rauischholzhausen, Germany
57.
Henkel,R (1997)
Die Zona pellucida als Induktor für die Akrosomreaktion.
Invited lecture at the Medical Society of Giessen, 11.06.97, Gießen, Germany
58.
Müller,C, Stürzebecher,J, Hesse,S, Henkel,R, Schill,W-B und Miska,E (1997)
Charakterisierung verschiedener Akrosininhibitoren vom Benzamidintyp.
5. Dreiländertagung Fertilität und Sterilität, 18.-20.09.97, Schwäbisch Gmünd, Germany
59.
Köhn,FM, Müller,C, Henkel,R, Habenicht,U-F and Schill,W-B (1997)
Einfluß des Angiotensin-Converting-Enzyme und von Angiotensinen auf die Funktion von
menschlichen Spermatozoen.
Symposium ”Molekulare Aspekte der Reproduktionsbiologie und -medizin”, Deutsches
Krebsforschungszentrum, 02.-03.10.97, Heidelberg, Germany
60.
Henkel,R (1997)
Jahreszeitliche Schwankungen der Ejakulatqualität.
4. Gießener Andrologisches Symposium, 15.11.97, Gießen, Germany
61.
Henkel,R, Müller,C, Stalf,T, Schill,W-B and Franken,DR (1998)
Use of failed-ferilized oocytes for diagnostic zona binding purposes after sperm binding
improvement.
29th SASOG Congress, 08.03.-12.03.98, Stellenbosch, South Africa
62.
Henkel,R, Sánchez,R and Schill,W-B (1998)
Sperm separation with SpermFertil® distinguishes between reactive oxygen species
generated by sperm or leukocytes.
29th SASOG Congress, 08.03.-12.03.98, Stellenbosch, South Africa
63.
Henkel,R (1999)
Biochemie und physiologische Bedeutung der Mantelfasern in menschlichen
Spermatozoen.
Vortrag am 27.06.99 auf Einladung von PD Dr. U.-F. Habenicht, Schering AG, Berlin,
Germany
64.
Henkel,R (1999)
The influence of different sperm functions on the fertilization process.
Invited lecture at the Department of Obsterics and Gynaecology, Reproductive Biology
Unit, Tygerberg Hospital, Tygerberg, South Africa, 12.08.99
65.
Henkel,R (1999)
Biochemie und Funktion der Mantelfasern in den Flagellen.
11. Jahrestagung der Deutschen Gesellschaft für Andrologie, 02.-04.09.99, Gießen
Prof. Ralf Henkel, PhD
63
66.
Seefeldt-Schmidt,B, Henkel,R, Schill,WB und Miska,W (1999)
Biochemische und immunologische Charakterisierung von niedermolekularen
Mantelfaserproteinen von Bullenspermatozoen.
11. Jahrestagung der Deutschen Gesellschaft für Andrologie, 02.-04.09.99, Gießen
67.
Henkel,R (1999)
Auswahlkriterien für das optimale Spermaaufbereitungsverfahren in der assistierten
Reproduktion.
Eingeladener Vortrag auf einer Fortbildungsveranstaltung am Zentrum für Dermatologie
und Andrologie der Justus Liebig Universität Gießen "Spermaaufbereitung mit praktischen
Übungen, 30.10.99, Gießen
68.
Henkel,R (1999)
Die Bedeutung funktioneller Parameter von Spermatozoen für den Fertilisationsprozeß.
Invited lecture at the Institute for Anatomy, University of Essen, Germany, 03.11.99
69.
Henkel,R (1999)
Die funktionelle Bedeutung von Mantelfasern in Säugerspermatozoen.
Invited lecture at the Institute for Anatomy and Cell Biology, Philipps University of
Marburg, Germany, 04.11.99
70.
Miska,W, Seefeldt-Schmidt,B and Henkel,R (2000)
Characterization of two distinct polypeptides in bovine outer dense fibers.
33. Jahrestagung "Physiologie und Pathologie der Fortpflanzung", 17.-18.02.00, Berlin,
Germany
71.
Henkel,R, Defosse,K, Weißmann,N and Miska,W (2000)
Assessment of the energy consumption of human spermatozoa related to motility.
33. Jahrestagung "Physiologie und Pathologie der Fortpflanzung", 17.-18.02.00, Berlin,
Germany
72.
Henkel, R, Baldauf, Ch, Bittner, J, Miska, W and Weidner, W (2000)
The importance of the elimination of zinc from spermatozoa during epididymal transit for
motility.
Invited lecture at the 4th Dies Andrologicus, 04.03.00, Marburg, Germany
73.
Henkel,R (2000)
Neue Aspekte zur Funktion der Mantelfasern in menschlichen Spermatozoen.
Invited lecture at the Department of Obstetrics and Gynaecology, University of Würzburg,
05.06.00, Würzburg, Germany
74.
Henkel,R (2000)
New aspects on the function of outer dense fibres in human spermatozoa.
Invited lecture at the Department of Human and Animal Physiology, Faculty of Science,
University of Stellenbosch, 27.07.00, Stellenbosch, South Africa
75.
Henkel,R (2000)
New aspects on the function of outer dense fibres in human spermatozoa.
Invited lecture at the Department of Medical Physiology, Medical Faculty, University of
Stellenbosch, 28.07.00, Tygerberg, South Africa
76.
Seefeldt-Schmidt,B, Henkel,R, Schill,W-B und Miska,W (2000)
Neue Erkenntnisse zum Aufbau der Mantelfasern in Spermatozoen.
XII. Jahrestagung der Deutschen Gesellschaft für Andrologie, 31.08.-02.09.00, Graz,
Österreich
Prof. Ralf Henkel, PhD
64
77.
Löffler,M, Dietz,C, Hayek-Ouassini,M, Henkel,R and Simmonds,A (2000)
Localization and function of dihydroorotate dehydrogenase of pyrimidine synthesis in
mammalian germ cells.
XVIIth International Arginine/Pyrimidine Conference, 09.-12.09.2000, Valencia, Spain
78.
Baldauf,Ch, Miska,W, Weidner,W und Henkel,R (2000)
Zinkeliminierung aus Flagellen ist essentiell für die Spermienmotilität.
50. Kongreß der Deutschen Gesellschaft für Urologie, 20.09.-23.09.00, Hamburg, Germany
79.
Heidorn,F, Henkel,R und Weiler,G (2000)
Sequenzanalyse mitochondrialer DNA an Einzelspermatozoen.
79. Jahrestagung der Deutschen Gesellschaft für Rechtsmedizin, 27.09.-30.09.2000, Essen,
Germany
80.
Henkel,R (2000)
Sperm functional assays.
Invited lecture at the 4th WHO Semenology Workshop for Sub-Sahara African Scientists,
02.-06.10.2000, Tygerberg, South Africa
81.
Henkel,R (2000)
Protein composition and function of outer dense fibres in mammalian spermatozoa.
Invited lecture at the Department of Medical Physiology, Medical Faculty, University of
Stellenbosch, 05.10.00, Tygerberg, South Africa
82.
Hayek-Ouassini,M, Fairbanks,LD, Henkel,R, Simmonds,HA, Rudnik,J, Löffler,M (2000)
Determination of pyrimidine and purine metabolites in human seminal plasma.
5th Dies Andrologicus, 25.11.00, Marburg, Germany
83.
Henkel,R (2001)
Role of reactive oxygen species in male infertility.
Invited lecture at the II. Jornadas de Medicina Reproductiva y Biologia de la Reproduccion,
04.-06.01.2001, Temuco, Chile
84.
Henkel,R (2001)
Seasonal changes in human sperm chromatin condensation.
Invited lacture at the Department of Obstetrics & Gynaecology, Facultad de Medicina,
Universidad de la Frontera, 12.01.2001, Temuco, Chile
85.
Henkel,R (2001)
Role of reactive oxygen species in male infertility.
Invited lecture at the Faculty of Medicine, Labortory for Reproductive Biology,
Universidad de Chile, 17.01.2001, Santiago, Chile
86.
Henkel,R (2001)
Seasonal changes in human sperm chromatin condensation.
Invited lecture at the Faculty of Medicine, Labortory for Reproductive Biology,
Universidad de Chile, 17.01.2001, Santiago, Chile
87.
Baldauf,Ch, Miska,W, Weidner,W and Henkel,R (2001)
Identification of a zinc binding protein in bovine epididymal fluid.
26. Veterinär-Humanmedizinische Gemeinschaftstagung, 22.-23.02.2001, Gießen,
Germany
Prof. Ralf Henkel, PhD
65
88.
Wroblewski,N, Miska,W, Weidner,W, Schill,W-B and Henkel,R (2001)
Influence on human sperm motility by addition of different chelators.
26. Veterinär-Humanmedizinische Gemeinschaftstagung, 22.-23.02.2001, Gießen,
Germany
89.
Miska,W, Peña,P, Sánchez,R, Vásquez,B, Vasconcellos,A and Henkel,R (2001)
Immunocytochemical localization of a CBG-like SERPIN in ovarian connective tissue.
26. Veterinär-Humanmedizinische Gemeinschaftstagung, 22.-23.02.2001, Gießen,
Germany
90.
Henkel,R (2001)
New results on the elimination of zinc during epididymal maturation of mammalian
spermatozoa.
Invited lecture at the Department of Obstetrics and Gynaecology, University of
Stellenbosch, Tygerberg, South Africa, 26.04.2001
91.
Henkel,R (2001)
New results on the elimination of zinc during epididymal maturation of mammalian
spermatozoa.
Invited lecture at the Department of Human and Animal Physiology, University of
Stellenbosch, Stellenbosch, South Africa, 03.05.2001
92.
Löffler,M, Hayek-Ouassini,M, Henkel,R, Rudnik,J, Fairbanks,L and Simmonds,A (2001)
Pyrimidines and purines in seminal plasma and the reproductive tract.
8th ESSPPMM-Symposium Bruges, Belgium, 16.-20.05.2001
93.
Henkel,R (2001)
Neue Erkenntnisse zur Eliminierung von Zink aus Säugerspermien während der
Nebenhodenreifung.
Gastvortrag am Institut für Reproduktionsmedizin der Tierärztlichen Hochschule
Hannover, 28.06.2001
94.
Henkel,R, Defosse,K, Weißmann,N, Schill,W-B, Miska,W (2001)
Human sperm zinc content and energy consumption.
45th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2001
95.
Henkel,R, Wroblewski,N, Miska,W, Schill,W-B (2001)
Dose-dependent effect of different chelators on motility of human spermatozoa.
45th Academic Yearday, University of Stellenbosch, South Africa, 22.-23.08.2001
96.
Slavov,M, Henkel,R, Steger,K, Bergmann,M, Weidner,W and Schroeder-Printzen,I (2001)
Chromatin condensation and expression of nuclear proteins in rabbit epididymal and
testicular spermatozoa and spermatids - preliminary results to establish an animal model
for seminal duct obstruction.
XIII. Jahrestagung der Deutschen Gesellschaft für Andrologie, 06.-08.09.2001, Berlin,
Germany
97.
Seefeldt-Schmidt,B, Henkel,R, Schill,W-B, Miska,W (2001)
Localization of a third protein component in mammalian outer dense fibers.
XIII. Jahrestagung der Deutschen Gesellschaft für Andrologie, 06.-08.09.2001, Berlin,
Germany
98.
Henkel,R (2001)
Advances in modern andrological diagnosis.
Invited lecture at the Genetics & IVF Institute, Fairfax, Virginia, USA, 08.11.2001
Prof. Ralf Henkel, PhD
99.
66
Henkel,R, Jung,A and Schill,W-B (2002)
Molecular aspects of declining sperm motility in older men.
3rd World Congress on The Aging Male, 07.-10.02.2002, Berlin, Germany
100. Monsees,TK, Kos,P, Schill,W-B and Henkel,R (2002)
Bradykinin-degrading proteases in peritubular cells of the rat testis.
35. Jahrestagung zur Physiologie und Pathologie der Fortpflanzung, 14.-15.02.2002,
Leipzig, Germany
101. Henkel (2002)
Vision of Research Development and Post-graduate Education.
Invited lecture at the Faculty of Health Sciences of the University of the Witwatersrand,
08.04.2002, Johannesburg, South Africa
102. Henkel,R, Baldauf,C, Wroblewski,N and Schill,W-B (2002)
Possible mechanism of the elimination of zinc from spermatozoa during epididymal
maturation.
Invited lecture at the Department of Obstetrics and Gynaecology, Reproductive Biology
Unit, Tygerberg Hospital, 25.04.2002, Tygerberg, South Africa
103. Henkel,R, Maaß,G, Bödeker,R-H, Scheibelhut,C, Stalf,T, Jung,A, Gips,H and Schill,W-B
(2002)
Do sperm function tests contribute to fertility prognosis?
Invited lecture at the 14th Jahrestagung der Deutschen Gesellschaft für Andrologie, 05.07.09.2002, Jena, Germany
104. Schill,W-B and Henkel,R (2002)
Sperm function tests and unexplained infertility.
Invited lecture at the 3rd Royan International Research Award, 11.-13.09.2002, Tehran, Iran
105. Henkel,R, Maaß,G, Hajimohammad,M, Menkveld,R, Stalf,T, Villegas,J, Sánchez,R,
Kruger,TF and Schill,W-B (2002)
Urogenital inflammation: Changes of leukocytes and ROS.
Invited lecture at the Joint Meeting of the European Society of Andrological Urology and
the European Society of Infection in Urology, 13.-14.09.2002, Giessen, Germany
106. Eickhoff,R, Baldauf,C, Wennemuth,G, Seitz,J, Suga,Y, Henkel,R and Meinhardt,A (2002)
Influence of the macrophage migration inhibitory factor (MIF) on the distribution of zinc
and sulfhydryl groups in maturing rat spermatozoa.
19. Arbeitstagung der Anatomischen Gesellschaft, 02.-04.10.2002, Würzburg, Germany
107. Seefeldt-Schmidt,B, Henkel,R, Schill,W-B and Miska,W (2002)
New findings on the cortical structure of mammalian outer dense fibres.
9th International Symposium on Spermatology, 06.-11.10.2002; Cape Town, South Africa
108. Henkel,R, Maaß,G, Bödeker,R-H, Scheibelhut,C, Stalf,T, Jung,A, Mehnert,C and
Schill,W-B (2002)
Impact of different sperm functions on fertilization and pregnancy.
Invited lecture at the First Asia-Pacific Forum on Andrology, 17.-21.10.2002, Shanghai,
China
109. Schill,W-B and Henkel,R (2002)
Sperm function tests and unexplained infertility.
Invited lecture at the Shanghai Institute of Andrology, 20.10.2002, Shanghai, China
Prof. Ralf Henkel, PhD
67
110. Henkel,R (2002)
Die Bedeutung von Spermatozoenfunktionsparametern für den Fertilisationsprozeß.
–Tragen Spermatozoen-Funktionstests zur Fertilitätsdiagnose bei?Invited Lecture at the VIIIth Sylt Workshop: „State of the ART in Endokrinologie und
Reproduktionsmedizin“, 08.-10.11.2002, Wenningstedt/Sylt, Germany
111. Henkel,R, Baldauf,C, Miska,W, Weidner,W, Schroeder-Printzen,I and Schill,W-B (2002)
Resorption of spermatozoal zinc in epididymis and vas deferens.
2. Tagung des Arbeitskreises Molekularbiologie der DGGEF, 15.-17.11.2002, Münster,
Germany
112. Henkel,R (2003)
What causes sperm DNA fragmentation-related pregnancy failure – Apoptosis or ROS?
Invited lecture at the Department of Obstetrics and Gynaecology, Reproductive Biology
Unit, Tygerberg Hospital, 20.02.2003, Tygerberg, South Africa
113. Henkel,R (2003)
Was ist Ursache für DNA-Fragmentation in Spermatozoen - Apoptose oder ROS?
Invited lecture at the Promega Seminar „Apoptose – Todsichere Assays“, 12.03.2003,
Gießen, Germany
114. Henkel,R (2003)
Resorption von Zink aus Spermatozoen während der Nebenhodenreifung.
Invited lecture at the Urological Clinic, University of Jena, 05.06.2003, Jena, Germany
115. Henkel,R, Kierspel,E, Hajimohammad,M, Stalf,T, Hoogendijk,C, Mehnert,C, Menkveld,R,
Schill,W-B and Kruger TF (2003)
Do reactive oxygen species affect sperm DNA fragmentation, fertilization and pregnancy in
IVF?
Joint Annual Meeting of the Deutsche Gesellschaft für Andrologie and Deutsche
Gesellschaft für Reproduktionsmedizin, 11.-13.09.2003, München, Germany
116. Henkel,R (2003)
DNA fragmentation of spermatozoa and ART.
Invited lecture at the 4th Biennial Alpha Conference, 8th Meeting of Modern ART &
Andrology in the 2000’s, 24.-27.09.2003, Antwerp, Belgium
117. Schill,W-B and Henkel,R (2003)
Sperm function and ART.
Invited lecture at the 48th Annual Meeting of the Japan Society of Fertility and Sterility,
01-03.10.2003, Tokyo, Japan
118. Henkel,R, Kierspel,E, Hajimohammad,M, Stalf,T, Mehnert,C, Hoogendijk,C, Menkveld,R,
Schill,WB, Gips,H and Kruger,TF (2003)
What causes Sperm DNA Fragmentation-related Pregnancy Failure - Apoptosis or ROS?
3. Tagung des Arbeitskreises Molekularbiologie der DGGEF, 07.-08.11.2003, Gießen,
Germany
119. Mehnert,C, Hendrischk,AK, Stalf,T, Tinneberg,H-R, Schill,W-B and Henkel,R (2004)
Establishment of a protein-free primary cell culture of bovine epididymal epithelial cells.
29. Veterinär-Humanmedizinische Gemeinschaftstagung, 19.-20.02.2004, München,
Germany
Prof. Ralf Henkel, PhD
68
120. Henkel,R, Kierspel,E, Stalf,T, Mehnert,C, Hoogendijk,C, Menkveld,R, Schill,W-B and
Kruger,TF (2004)
Assessment of the effect of intrinsic and extrinsic ROS on sperm functions.
29. Veterinär-Humanmedizinische Gemeinschaftstagung, 19.-20.02.2004, München,
Germany
121. Henkel,R (2004)
Causes of sperm DNA fragmentation and its effect on the outcome of assisted
reproduction.
Invited lecture at the Department of Medical Physiology, Medical Faculty, University of
Stellenbosch, 12.03.04, Tygerberg, South Africa
122. Schill,W-B and Henkel,R (2004)
Sperm function and outcome of assisted reproduction.
Invited lecture at the 1st World Congress and Workshops on Assisted Fertilization,
Conception and Molecular Reproduction, 13.-19.03.2004, Cairo, Egypt
123. Henkel,R (2004)
Was muß der Urologe über die andrologische Diagnostik wissen? – Von den Grundlagen
bis zur hochspezialisierten Diagnostik.
Invited lecture at the „Fortbildungsveranstaltung: „Andrologie“ Was muß der Urologe
wissen? Was gibt es Neues?“, Department of Urology, University of Jena, 03.11.2004,
Jena, Germany
124. Henkel,R (2005)
Die Bedeutung von Spermatozoenfunktionsparameters für den Fertilisationsprozeß.
Invited lecture at the Emeriti Association of the Faculty of Medicine of the University of
Jena. 25.01.2005; Jena, Germany
125. Hoogendijk,CF, Kruger,TF, de Beer,ML, Siebert,TI, Henkel,R (2005)
Improvement in early human embryo development using SAGE QA Sequential stagespecific culture mediums.
4th BDSA Congress of Obstetrics and Gynaecology, Stellenbosch, South Africa, 27.29.01.2005
126. Henkel,R, (2005)
The importance of the elimination of zinc from spermatozoa during epididymal maturation.
Invited lecture at the Faculty of Science, Department of Medical Biosciences, University of
the Western Cape, Bellville, South Africa, 12.04.2005
127. Henkel,R, (2005)
Sperm DNA fragmentation and assisted reproduction.
Invited lecture at the Department of Medical Biosciences, University of the Western Cape,
Bellville, South Africa, 12.04.2005
128. Henkel,R (2005)
Apoptose in männlichen Keimzellen.
Invited lecture at the “Embryologenforum Austria”, Landes- Frauen- und Kinderklinik
Linz, 16.04.2005, Linz, Austria
129. Henkel, R (2005)
Der Einfluß von Oxidantien und Leukozyten auf Spermienfunktionen.
Invited lecture at the “Embryologenforum Austria”, Landes- Frauen- und Kinderklinik
Linz, 16.04.2005, Linz, Austria
Prof. Ralf Henkel, PhD
69
130. Henkel,R (2005)
Welchen Beitrag leisten die Spermatozoenfunktionstests zur Fertilitätsdiagnose?
Invited lecture at the 45th Meeting of the „Deutsche Dermatologische Gesellschaft“, 20.23.04.2005, Dresden, Germany
131. Hoogendijk,CF, Kruger,TF, de Beer,ML, Siebert,TI, Henkel,R (2005)
A Study of two Sequential Mediums: The impact on Embryo Quality and Pregnancy rates.
13th World Congress on In Vitro Fertilization, Assisted Reproduction and Genetics, 26.29.05.2005, Istanbul, Turkey
132. Henkel,R (2005)
Einfluß von Entzündungen des Urogenitaltraktes auf die Spermienfunktion.
Invited lecture at the XXII. Fortbildung Andrologie „Einschränkung des
Fertilitätspotentials – eine interdisziplinäre Herausforderung“, Department of Urology,
University of Jena, 03.-04.06.2005, Jena, Germany
133. Henkel,R, Stalf,T, Mehnert,C, Menkveld,R, Schill,W-B, Schubert,J, Kruger,TF (2005)
Effect of extrinsic ROS on sperm functions.
8th International Congress of Andrology, 12.-16.06.2005, Seoul, Korea
134. Henkel,R (2005)
The impact of oxidants on sperm function.
Invited lecture at the International Workshop “"Molecular Andrology: Testicular Pathology
- Androgen Action - Sperm Function", 07.-09.10.2005, Gießen, Germany
135. Schuppe,H-C, Jung,A, Maaß,G, Haidl,G, Schill,W-B, Henkel,R (2006)
A perspective on "inflamm-aging" of the male genital tract: age-related changes in seminal
PMN-elastase.
5th World Congress on the Aging Male, 09.-12.02.2006, Salzburg, Austria
136. Schuppe,H-C, Maaß,G, Jung,A, Schill,W-B, Henkel,R (2006)
High flagellar zinc concentration is responsible for decreased sperm motility in ageing
men.
5th World Congress on the Aging Male, 09.-12.02.2006, Salzburg, Austria
137. Mehnert,C, Schuppe,H-C, Stalf,T, Henkel,R, Tinneberg,H-R (2006)
An in vitro model for epididymal sperm maturation.
39th Annual Conference of Physiology and Pathology of Reproduction and 31st Mutual
Conference on Veterinary and Human Reproductive Medicine, 16.-17.02.2006, Hannover,
Germany
138. Schuppe,H-C, Mehnert,C, Fechner,C, Stalf,T, Tinneberg,H-R, Henkel,R (2006)
Ein in-vitro-Modell für die epididymale Spermienreifung.
18. Annual Congress of the German Society of Andrology, 07.-09.09.2006, Düsseldorf,
Germany
139. Henkel,R (2006)
DNA fragmentation of spermatozoa and assisted reproductive technology.
Invited lecture at the “Male Infertility and ART”, 06.-07.10.06, Rome, Italy
140. Henkel,R, Sturmhoefel,A, Schreiber,G, Hipler,UC, Zermann,DH, Menkveld,R (2006)
Comparison of three methods to evaluate human sperm morphology.
2nd Asia-Pacific Forum on Andrology, 26.-30.10.2006, Shanghai, China
Prof. Ralf Henkel, PhD
70
141. Henkel,R (2007)
Research Development in the Department of Medical Biosciences.
Invited lecture at the departmental (MBS) research seminar series, 15.02.07, Bellville,
South Africa
142. Henkel,R (2007)
DNA based sperm assessment.
Invited lecture at the IFFS 2007 Workshop “Andrology in Assisted Reproduction” held at
the 19th World Congress on Fertility and Sterility, 29.04.-03.05.2007, Durban, South Africa
143. Henkel,R (2007)
DNA based sperm assessment and its impact on assisted reproduction.
Invited lecture at the 19th World Congress on Fertility and Sterility, 29.04.-03.05.2007,
Durban, South Africa
144. Henkel,R, Sturmhoefel,A, Hipler,UC, Zermann,DH, Schreiber,G and Menkveld,R (2007)
Human sperm morphology evaluated by means of Testsimplets® is not comparable with
standard procedures.
19th World Congress on Fertility and Sterility, 29.04.-03.05.2007, Durban, South Africa
145. Henkel,R, Ludwig,M, Schuppe,H-C, Diemer,T, Schill,W-B and Weidner,W (2007)
Chronic pelvic pain syndrome affects acrosome reaction in human spermatozoa.
51st Academic Yearday, Faculty of Health Sciences, Tygerberg Hospital and University of
Stellenbosch, 15.-16.08.2007, Stellenbosch, South Africa
146. Hoogendijk,CF, Kruger,TF, Bouic,PJD, Henkel,R (2007)
The relationship between human sperm apoptosis and normal sperm morphology.
51st Academic Yearday, Faculty of Health Sciences, Tygerberg Hospital and University of
Stellenbosch, 15.-16.08.2007, Stellenbosch, South Africa
147. Henkel,R (2007)
DNA based sperm assessment and its impact on assisted reproduction outcome.
Invited lecture at the departmental (MBS) research seminar series, 16.08.07, Bellville,
South Africa
148. Henkel,R (2007)
Hormonal control of the testes.
Invited lecture at the 10th WHO Semenology Workshop, Faculty of Health Sciences,
Tygerberg Hospital and University of Stellenbosch, 06.12.07, Tygerberg, South Africa
149. Henkel,R (2007)
The acrosome reaction.
Invited lecture at the 10th WHO Semenology Workshop, Faculty of Health Sciences,
Tygerberg Hospital and University of Stellenbosch, 06.12.07, Tygerberg, South Africa
150. Henkel,R (2008)
DNA based sperm assessment and its impact on assisted reproduction outcome.
Invited lecture at a departmental seminar at the Department of Obstetrics and Gynaecology,
University of Stellenbosch, Tygerberg Hospital, 21.04.08, Tygerberg, South Africa
151. Fransman,WO, Weitz,F, Menkveld,R, Kruger,TF, Henkel,R (2008)
In vitro effects of Typha capensis rhizome extract on sperm parameters.
11th Indigenous Plant Use Forum (IPUF), 07.-10.07.08, Graaff-Reinet, South Africa
Prof. Ralf Henkel, PhD
71
152. Henkel,R, Fransman,W, Hipler,UC, Schreiber,G, Weitz,F, Kruger,TF, Fisher,D,
Menkveld,R (2008)
Typha capensis extracts decrease ROS production and affect human sperm functions.
4th World Congress on Medicinal and Aromatic Plants, 9.-14.11.08, Cape Town, South
Africa
153. Mars,JA, Weitz,F, Fisher,D, Henkel,R (2008)
Determination of trace elements in aqueous herbal extracts to be used in male infertility.
4th World Congress on Medicinal and Aromatic Plants, 9.-14.11.08, Cape Town, South
Africa
154. Henkel,R (2008)
Sperm functional tests.
Invited lecture at the 11th World Health Organization “Semenology and Cervical Cytology
Workshop”.
Faculty of Health Sciences, Tygerberg Hospital and University of Stellenbosch, 01.05.12.08, Tygerberg, South Africa
155. Henkel,R (2009)
Sperm Preparation: State of-the-ART.
Invited Keynote Lecture at the 3rd Asia-Pacific Forum on Andrology 10.-13.10.2009,
Nanjing, China
Prof. Ralf Henkel, PhD
72
Scientific Awards:
1.
Best Poster of the Congress:
Dreiländertagung Fertilität und Sterilität 29.05.-01.06.91, Goslar, FRG
Fehl,P, Henkel,R, Kleinstein,J und Miska,W (1991)
Induktion der Akrosomreaktion durch humane Follikularflüssigkeit.
2.
First Poster Prize in "Gold":
XIV. World Congress on Fertility and Sterility, 22.11.-27..11.92, Caracas, Venezuela
Henkel,R, Stalf,T, Miska,W, Gips,H and Schill,W-B (1992)
Isolation and partial characterization of the outer dense fiber proteins of human
spermatozoa.
3.
Second Poster Award:
IX. World Congress on In Vitro Fertilization and Assisted Reproduction, 03.-07.04.95,
Vienna, Austria
Henkel,R, Schaller,J, Glander,H-J and Schill,W-B (1995)
Investigation of adhesion molecules and matrix proteins on human sperm with different
binding and penetration properties in the HOP-test.
4.
Nominee for the Humboldt-South African Research Award (2005)
5.
Award for Research Excellence on prostatitis research by the Prostatitis Foundation (2006)
Prize was awarded for the paper Henkel,R, Ludwig,M, Schuppe,H-C, Diemer,T, Schill,WB and Weidner,W (2006); Chronic pelvic pain syndrome and prostatitis affect the
acrosome reaction in human spermatozoa. World J Urol 24: 39-44
6.
Best Poster of the Conference Session
51st Academic Yearday, Faculty of Health Sciences, Tygerberg Hospital and University of
Stellenbosch, 15.-16.08.2007, Stellenbosch, South Africa
Menkveld,R, Henkel,R, Schüller,S, Hoppe,I and Starker,W (2007); An investigation of the
relationships between sperm morphology parameters, reactive oxygen species production
in spermatozoa and sperm DNA status.
7.
Best Poster of the Honours Section
Research Open Day at the University of the Western Cape, 01.-02.11.2007, Bellville, South
Africa
Fransman,W, Menkveld,R, Kruger,T, Hoogendijk,C, Weitz,F, Henkel,R (2007); In vitro
effects of Typha capensis extracts on sperm motility and mitochondrial membrane
potential.
8.
Best Poster of the PhD/post-doc Section
Research Open Day at the University of the Western Cape, 28.-29.11.2008, Bellville, South
Africa
Mars,JA, Henkel,R, Fisher,D, Weitz,F (2008)
Determination of selenium in aqueous herbal extracts to be used fertility studies.