Publications Prof. Heuser before 2001

ISABELLA HEUSER
P UBL I CA TIO NS
S INCE 20 01
2014
Aust S, Stasch J, Jentschke S, Alkan Härtwig E, Koelsch S, Heuser I, Bajbouj M
(2014) Differential effects of early life stress on hippocampus and amygdala
volume as a function of emotional abilities. Hippocampus Apr 17 (epub)
Hellmann-Regen J, Herzog I, Fischer N, Heuser I, Regen F (2014) Do tetracyclines
and erythromycin exert anti-acne effects by inhibition of P450-mediated
degradation of retinoic acid? Exp Dermatol 23:290-3
Morgen K, Ramirez A, Frölich L, …, Peters O, … Heuser I et al. (2014) Genetic
interaction of PICALM and APOE is associated with brain atrophy and
cognitive impairment in Alzheimer's disease. Alzheimer’s & Dementia March
6 (epub)
Deuschle M, Schilling C, Leweke FM, Enning F, Pollmächer T, Esselmann H,
Wiltfang J, Frölich L, Heuser I (2014) Hypocretin in cerebrospinal fluid is
positively correlated with Tau and pTau. Neurosci Lett 561:41-5
Dukart J, Regen F, Kherif F, Colla M, Bajbouj M, Heuser I, Frackowiak RS,
Draganski B (2014) Electroconvulsive therapy-induced brain plasticity
determines therapeutic outcome in mood disorders. Proc Natl Acad Sci USA
111:1156-61
Gaebel W, Riesbeck M, Wölwer W, Klimke A, Eickhoff M, von Wilmsdorff M, Heuser
I, Maier W, Klosterkötter J, Falkai P, Schlösser R, Schmitt A, Riedel M,
Klingberg S, Köpcke W, Ohmann C, Möller HJ (2014) Rates and predictors of
remission in first-episode schizophrenia within 1year of antipsychotic
maintenance treatment. Results of a randomized controlled trial within the
German Research Network on Schizophrenia. Schizophr Res 152:478-86
Kuhn-Thiel AM, Weiß C, Wehling M … Heuser I … et al (2014) Consensus
Validation of the FORTA (Fit fOR The Aged) List: A Clinical Tool for
Increasing the Appropriateness of Pharmacotherapy in the Elderly. Drugs
Aging 31:131-140
Liu G, Yao L, Liu J, Jiang Y, Ma G; Genetic and Environmental Risk for Alzheimer's
disease (GERAD1) Consortium, Chen Z, Zhao B, Li K (2014) Cardiovascular
disease contributes to Alzheimer's disease: evidence from large-scale
genome-wide association studies. Neurobiol Aging 35:786-92
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Regen F, Heuser I, Herzog I, Hellmann-Regen J (2014) Striking Growth-inhibitory
Effects of Minocycline on Human Prostate Cancer Cell Lines. Urology 83:509
Seemüller F, Meier S, Obermeier M, Musil R, Bauer M, Adli M, Kronmüller K,
Holsboer F, Brieger P, Laux G, Bender W, Heuser I, Zeiler J, Gaebel W,
Riedel M, Falkai P, Möller HJ (2014) Three-Year long-term outcome of 458
naturalistically treated inpatients with major depressive episode: severe
relapse rates and risk factors. Eur Arch Psychiatry Clin Neurosci Mar 4
(epub)
2013
Alkan Härtwig E, Aust S, Heuser I (2013) HPA system activity in alexithymia: A
cortisol awakening response study. Psychoneuroendocrinology 38:2121-6
Aust S, Alkan Härtwig E, Koelsch S, Heekeren HR, Heuser I, Bajbouj M (2013) How
emotional abilities modulate the influence of early life stress on hippocampal
functioning. Soc Cogn Affect Neurosci 38:2121-6
Brakemeier EL, Merkl A, Wilbertz G, Quante A, Regen F, Bührsch N, van Hall F,
Kischkel E, Danker-Hopfe H, Anghelescu I, Heuser I, Kathmann N, Bajbouj M
(2013) Cognitive-Behavioral Therapy as Continuation Treatment to Sustain
Response After Electroconvulsive Therapy in Depression: A Randomized
Controlled Trial. Biol Psychiatry Dec 12 (epub)
Bruehl H, Preißler S, Heuser I, Heekeren HR, Roepke S, Dziobek I (2013)
Increased prefrontal cortical thickness is associated with enhanced abilities
to regulate emotions in PTSD-free women with borderline personality
disorder. PLoS One Jun 5, 8
Chapman J, Rees E, Harold D, Ivanov D, Gerrish A, Sims R, Hollingworth P,
Stretton A; GERAD1 Consortium: … Heuser I … Holmans P, Owen MJ,
O'Donovan MC, Williams J, Kirov G (2013) A genome-wide study shows a
limited contribution of rare copy number variants to Alzheimer's disease risk.
Hum Mol Genet 22:816-24
Guerreiro R, Wojtas A, Bras J, Carrasquillo M, Rogaeva E, Majounie E, Cruchaga
C, Sassi C, Kauwe JS, Younkin S, Hazrati L, Collinge J, Pocock J, Lashley T,
Williams J, Lambert JC, Amouyel P, Goate A, Rademakers R, Morgan K,
Powell J, St George-Hyslop P, Singleton A, Hardy J; Alzheimer Genetic
Analysis Group (2013) TREM2 variants in Alzheimer's disease. N Engl J Med
368:117-27
European Alzheimer's Disease Initiative (EADI); Genetic and Environmental Risk in
Alzheimer's Disease; Alzheimer's Disease Genetic Consortium et al. (2013)
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for
Alzheimer's disease. Nat Genet 45:1452-8
Harold D, Abraham R, Hollingworth P, …, Heuser I … et al (2013) Genome-wide
association study identifies variants at CLU and PICALM associated with
Alzheimer's disease. Nat Genet May 29, 45:712
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Hellmann-Regen J, Heuser I, Regen F (2013) UV-A emission from fluorescent
energy-saving light bulbs alters local retinoic acid homeostasis. Photochem
Photobiol Sci 12:2177-85
Lee SH, Harold D, ...., Heuser I ... et al (2013) Estimation and partitioning of
polygenic variation captured by common SNPs for Alzheimer's disease,
multiple sclerosis and endometriosis. Hum Mol Genet 22:832-41
Morgen K, Frölich L, Tost H, Plichta MM, Kölsch H, Rakebrandt F, Rienhoff O,
Jessen F, Peters O, Jahn H, Luckhaus C, Hüll M, Gertz HJ, Schröder J,
Hampel H, Teipel SJ, Pantel J, Heuser I, Wiltfang J, Rüther E, Kornhuber J,
Maier W, Meyer-Lindenberg A (2013) APOE-dependent phenotypes in
subjects with mild cognitive impairment converting to Alzheimer's disease. J
Alzheimers Dis 37:389-401
Musil R, Zill P, Seemüller F, Bondy B, Meyer S, Spellmann I, Bender W, Adli M,
Heuser I, Fisher R, Gaebel W, Maier W, Rietschel M, Rujescu D, Schennach
R, Möller H-J, Riedel M (2013) Genetics of emergent suicidality during
antidepressive treatment − Data from a naturalistic study. Eur
Neuropsychopharmacol 23:663-74
Musil R, Zill P, Seemüller F, Bondy B, Obermeier M, Spellmann I, Bender W, Adli
M, Heuser I, Zeiler J, Gaebel W, Maier W, Rietschel M, Rujescu D,
Schennach R, Möller HJ, Riedel M (2013) No influence of brain-derived
neurotrophic factor (BDNF) polymorphisms on treatment response in a
naturalistic sample of patients with major depression. Eur Arch Psychiatry
Clin Neurosci 263:405-12
Schennach R, Riesbeck M, Mayr A, Seemüller F, Maier W, Klingberg S, Heuser I,
Klosterkötter J, Gastpar M, Schmitt A, Sauer H, Schneider F, Jäger M,
Wölwer W, Gaebel W, Möller HJ, Riedel M (2013) Should early improvement
be re-defined to better predict the maintenance of response in first-episode
schizophrenia patients? Acta Psychiatr Scand 127:474-81
Schilling C, Gilles M, Blum WF, Daseking E, Colla M, Weber-Hamann B,
Lederbogen F, Krumm B, Heuser I, Wudy SA, Kopf D, Deuschle M (2013)
Leptin plasma concentrations increase during antidepressant treatment with
amitriptyline and mirtazapine, but not paroxetine and venlafaxine: leptin
resistance mediated by antihistaminergic activity? J Clin Psychopharmacol
33:99-103
Schulze L, Dziobek I, Vater A, Heekeren HR, Bajbouj M, Renneberg B, Heuser I,
Roepke S (2013) Gray matter abnormalities in patients with narcissistic
personality disorder. J Psychiatr Res 47:1363-9
Zeugmann S, Buehrsch N, Bajbouj M, Heuser I, Anghelescu I, Quante A (2013)
Childhood maltreatment and adult proinflammatory status in patients with
major depression. Psychiatr Danub 2013 25:227-35
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Zou F, Belbin O, Carrasquillo MM, Culley OJ, Hunter TA, Ma L, Bisceglio GD, Allen
M, Dickson DW, Graff-Radford NR, Petersen RC; Genetic and Environmental
Risk for Alzheimer’s disease (GERAD1) Consortium, Morgan K, Younkin SG
(2013) Linking protective GAB2 variants, increased cortical GAB2 expression
and decreased Alzheimer's disease pathology. PLoS One May 28, 8
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2012
Aust S, Alkan Härtwig E, Heuser I, Bajbouj M (2012) The role of early emotional
neglect in alexithymia. Psychological Trauma Theory Research Practice and
Policy 02/2012
Evers A, Klusmann V, Schwarzer R, Heuser I (2012) Adherence to physical and
mental activity interventions: Coping plans as a mediator and prior adherence
as a moderator. Br J Health Psychol 17:477-91
Evers A, Klusmann V, Schwarzer R, Heuser I (2012) Does adherence moderate the
effect of physical or mental training on episodic memory in older women?
Advances in Physical Education 2:68-72
Evers A, Klusmann V, Ziegelmann JP, Schwarzer R, Heuser I (2012) Long-term
adherence to a physical activity intervention: The role of telephone-assisted
vs. self-administered coping plans and strategy use. Psychol Health 27:78497
Gerrish A, Russo G, Richards A, … Heuser I, Kornhuber J, Wiltfang J, …. Williams
J (2012) The Role of Variation at AβPP, PSEN1, PSEN2, and MAPT in Late
Onset Alzheimer's Disease. J Alzheimers Dis 28:377-87
Grimm S, Luborzewski A, Schubert F, Merkl A, Kronenberg G, Colla M, Heuser I,
Bajbouj M (2012) Region-specific glutamate changes in patients with unipolar
depression. J Psychiatric Res 46:1059-65
Hellmann J, Jüttner R, Roth C, Bajbouj M, Kirste I, Heuser I, Gertz K, Endres M,
Kronenberg G (2012) Repetitive magnetic stimulation of human-derived
neuron-like cells activates cAMP-CREB pathway. Eur Arch Psychiatry Clin
Neurosci 262:87-91
Körting J, Pukrop R, Klein P, Ritter K, Knowles M, Banzhaf A, Gentschow L, Vater
A, Heuser I; Colla M, Röpke S (2012) Comparing dimensional models
assessing personality traits and personality pathology amongst adult ADHD
and Borderline Personality Disorder. J Atten Disord Nov 27 (epub)
Kronenberg G, Balkaya M, Prinz V, Gertz K, Ji S, Kirste I, Heuser I, Kampmann B,
Hellmann-Regen J, Gass P, Sohr R, Hellweg R, Waeber C, Juckel G,
Hörtnagl H, Stumm R, Endres M (2012) Exofocal dopaminergic degeneration
as antidepressant target in mouse model of poststroke depression. Biol
Psychiatry 72:273-81
Peters O, Lorenz D, Fesche A, Schmidtke K, Hüll M, Perneczky R, Rüther E, Möller
HJ, Jessen F, Maier W, Kornhuber J, Jahn H, Luckhaus C, Gertz HJ,
Schröder J, Pantel J, Teipel S, Wellek S, Frölich L, Heuser I (2012) A
combination of galantamine and memantine modifies cognitive function in
subjects with amnestic MCI. J Nutr Health Aging 16:544-8
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Peth J, Regen F, Bajbouj M, Heuser M, Anghelescu I, Hornung OP (2012) The
influence of daytime napping versus controlled activity on the subjective wellbeing of patients with major depression. Psychiatry Res 200:368-73
Riedel M, Mayr A, Seemüller F, Maier W, Klingberg S, Heuser I, Klosterkötter J,
Gastpar M, Schmitt A, Sauer H, Schneider F, Gaebel W, Jäger M, Möller H-J,
Schennach-Wolff R (2012) Depressive symptoms and their association with
acute treatment outcome in first-episode schizophrenia patients: Comparing
treatment with risperidone and haloperidol. World J of Biol Psychiatry 13:30-8
Riedel O, Dodel R, Deuschl G, Klotsche J, Förstl H, Heuser I, Oertel W, Reichmann
H, Riederer P, Trenkwalder C, Wittchen HU (2012) Depression and caredependency in Parkinson’s Disease: results from a nationwide study of 1,449
outpatients. Parkinsonism and Related Disorders. Parkinsonism Relat Disord
18:598-601
Schennach R, Meyer S, Seemüller F, Jäger M, Schmauss M, Laux G, Pfeiffer H,
Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke
MR, Rüther E, Klingberg S, Gastpar M, Möller H-J, Riedel M (2012) Insight in
schizophrenia – course and predictors during the acute treatment phase of
patients suffering from a schizophrenia spectrum disorder. Eur Psychiatry
27:625-33
Schennach R, Meyer S, Seemüller F, Jäger M, Schmauss M, Laux G, Pfeiffer H,
Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke
MR, Rüther E, Klingberg S, Gastpar M, Musil R, Möller HJ, Riedel M (2012)
Response trajectories in "real-world" naturalistically treated schizophrenia
patients. Schizophr Res 139:218-24
Schennach R, Obermeier M, Meyer S, Jäger M, Schmauss M, Laux G, Pfeiffer H,
Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke
MR, Rüther E, Klingberg S, Gastpar M, Seemüller F, Möller HJ, Riedel M
(2012) Predictors of relapse in the year after hospital discharge among
patients with schizophrenia. Psychiatr Serv 63:87-90
Schennach R, Obermeier M, Seemüller F, Jäger M, Schmauss M, Laux G, Pfeiffer
H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W,
Lemke MR, Rüther E, Klingberg S, Gastpar M, Riedel M, Möller HJ (2012)
Evaluating depressive symptoms in schizophrenia: a psychometric
comparison of the calgary depression scale for schizophrenia and the
hamilton depression rating scale. Psychopathology 45:276-85
Schennach R, Riedel M, Obermeier M, Jäger M, Schmauss M, Laux G, Pfeiffer H,
Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke
MR, Rüther E, Klingberg S, Gastpar M, Seemüller F, Möller H-J (2012)
Remission and recovery and their predictors in schizophrenia spectrum
disorder – results from a 1-year follow-up naturalistic trial. Psychiatr Q
83:187-207
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Schipke CG, Peters O, Heuser I, Grimmer T, Sabbagh MN, Sabri O, Hock C, Kunz
M, Kuhlmann J, Reininger C, Blankenburg M (2012) Impact of Beta-AmyloidSpecific Florbetaben PET Imaging on Confidence in Early Diagnosis of
Alzheimer's Disease. Dement Geriatr Cogn Disord 33:416-22
Seemüller F, Riedel M, Obermeier M, Schennach-Wolff R, Spellmann I, Meyer S,
Bauer M, Adli M, Kronmüller K, Ising M, Brieger P, Laux G, Bender W, Heuser
I, Zeiler J, Gaebel W, Möller HJ (2012) The validity of self-rated psychotic
symptoms in depressed inpatients. Eur Psychiatry 27:547-52
Seemüller F, Schennach R, Mayr A, Musil R, Jäger M, Maier W, Klingenberg S,
Heuser I, Klosterkötter J, Gastpar M, Schmitt A, Schlösser R, Schneider F,
Ohmann C, Lewitzka U, Gaebel W, Möller H-J, Riedel M (2012) Akathisia and
suicidal ideation in first episode schizophrenia. J Clin Psychopharmacol
32:694- 8
Spellmann I, Riedel M, Schennach R, Seemüller F, Obermeier M, Musil R, Jäger M,
Schmauß M, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W,
Klosterkötter J, Heuser I, Maier W, Lemke MR, Rüther E, Klingberg S, Gastpar
M, Möller HJ (2012) One-year functional outcomes of naturalistically treated
patients with schizophrenia. Psychiatry Res 198:378-85
Zeugmann S, Quante A, Popova-Zeugmann L, Kössler W, Heuser I, Anghelescu I
(2012) Pathways linking early life stress, metabolic syndrome, and the
inflammatory marker fibrinogen in depressed inpatients. Psychiatr Danub
24:57-65
2011
Barthel H, Gertz HJ, Dresel S, Heuser I, Bartenstein P, Bürger K, Hiemeyer F,
Wittemer-Rump S, Seibyl J, Reininger C, Sabri O (2011) Cerebral amyloid-ß
with Florbetaben (18F) in patients with Alzheimer’s Disease and healthy
controls: A multicentre phase 2 diagnostic study. Lancet Neurol 10:424-35
Dziobek I, Preissler S, Grozdanovic Z, Heuser I, Heekeren H, Röpke S (2011).
Neuronal correlates of altered empathy and social cognition in borderline
personality disorder. Neuroimage 57:539-48
Evers A, Klusmann V, Schwarzer R, Heuser I (2011) Improving cognition by
adherence to physical or mental exercise: A moderated mediation analysis.
Aging & Mental Health 15:446-55
Frings L, Klöppel S, Teipel S, Peters O, Frölich L, Pantel J, Schröder J, Gertz H-J,
Arlt S, Heuser I, Kornhuber J, Wiltfang J, Maier W, Jessen F, Hampel H, Hüll
M (2011). Left anterior temporal lobe sustains naming in Alzheimer’s Dementia
and mild cognitive impairment. Curr Alzheimer Res 8:893-901
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Gaebel W, Riesbeck M, Wölwer W, Klimke A, Eickhoff M, von Wilmsdorff M, Lemke
M, Heuser I, Maier W, Huff W, Schmitt A, Sauer H, Riedel M, Klingberg S,
Köpcke W, Ohmann C, Möller HJ (2011) Relapse prevention in first-episode
schizophrenia-maintenance vs intermittent drug treatment with prodromebased early intervention: Results of a randomizd controlled trial within the
german research network on schizophrenia. J Clin Psychiatry 72:205-18
Hellmann J, Heuser I, Kronenberg G (2011) Targeted prevention of posttraumatic
stress disorder (in German). Nervenarzt 82:834-41
Henkel V, Seemüller F, Obermeier M, Adli M, Bauer M, Kronmüller K, Holsboer F,
Brieger P, Laux G, Bender W, Heuser I, Zeiler J, Gaebel W, Mayer A, Riedel
M, Möller HJ (2011). Relationship between baseline severity of depression and
clinical trial outcome. Pharmacopsychiatry 44:27-32
Hollingworth P, Harold D, …, Heuser I et al (2011) Common variants at ABCA7,
MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's
disease. Nat Genet 43:429-35
Klein JP, Schweiger U, Heuser I, Colla M (2011) Einfluss von Psychotherapie und
Pharmakotherapie auf die Hirnaktivität bei depressiven Patienten.
Psychotherapie 16:277-283
Klusmann V. Evers A. Schwarzer R, Heuser I (2011) A brief questionnaire on
metacognition: Psychometric propertis. Aging & Mental Health 15:1052-62
Klusmann V, Evers A, Schwarzer R, Heuser I (2011). Activity experiences shape
perceived fitness trajectories: Results from a 6-month randomized controlled
trial in older women. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn
18:328-39
Klusmann V, Evers A, Schwarzer R, Heuser I (2011) Views on aging and emotional
benefits of physical activity: Effects of an exercise intervention in older women.
Psychology of Sport and Exercise 13:236-42
Luborzewski A, Peters O, Heuser I (2011) Prävention mit Statinen – Wunsch und
Wirklichkeit. DNP – Der Neurologe und Psychiater 13:59-61
Mache S, Kloss L, Heuser I, Klapp BF, Groneberg DA (2011) Real time analysis of
psychiatrists’ workflow in German hospitals. Nord J Psychiatry 65:112-6
Merkl A, Schubert F, Quante A, Luborzewski A, Brakemeier EL, Grimm S, Heuser I,
Bajbouj M (2011) Abnormal cingulate and prefrontal cortical neurochemistry in
major depression after electroconvulsive therapy. Biol Psychiatry 69:772-9
Paslakis G, Kopf D, Westphal S, Gilles M, Lederbogen F, Hamann B, Heuser I,
Deuschle M (2011) Treatment with paroxetine, but not amitriptyline, lowers
levels of lipoprotein(a) in patients with major depression. J Psychopharmacol
25:1344-6
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Paslakis G, Krumm B, Gilles M, Schweiger U, Heuser I, Richter I, Deuschle M (2011)
Discrimination between patients with melancholic depression and healthy
controls: comparison between 24-h cortisol profiles, the DST and the Dex/CRH
test. Psychoneuroendocrinology 2011 36:691-8
Paslakis G, Lecei O, Stalla GK, Landgraf R, Uhr M, Hamann B, Luppa P, Gilles M,
Heuser I, Deuschle M (2011) The effect of treatment with ketoconazole on
central CRH systems of depressed patients. Hum Psychopharmacol 26:35-40
Riedel M, Dodel R, Deuschl G, Foerstl H, Henn F, Heuser I, Oertel W, Reichmann H,
Riederer P, Trenkwalder C, Wittchen HU (2011) [Dementia and depression
determine care dependencyin Parkinson’s disease: analysis of 1,449
outpatients receiving nursing care in Germany] Demenz und Depression
determinieren Pflegebedürftigkeit bei M. Parkinson (Article in German).
Nervenarzt 82:1012-9
Riedel M, Möller HP, Obermeier M, Adli M, Bauer M, Kronmüller K, Brieger P, Laux
G, Bender WE, Heuser I, Zeiler J, Gaebel W, Schennach-Wolff R, Henkel V,
Seemüller F (2011) Clinical predictors of response and remission in inpatients
with depressive syndromes. Affect Disord 133:137-49
Röpke S, Luborzewski A, Schindler F, Quante A, Anghelescu I, Heuser I, Bajbouj M
(2011) Stimulus pulse-frequency-dependent efficacy and cognitive adverse
effects of ultrabrief-pulse electroconvulsive therapy in patients with major
depression. J ECT 27:109-13
Röpke S, Schröder-Abé M, Schütz A, Jacob G, Dams A, Vater A, Rüter A, Merkl A,
Heuser I; Lammers CH (2011) Dialectic behavioural therapy has an impact on
self-concept clarity and facets of self-esteem in women with borderline
personality disorder. Clin Psychol Psychother 26:284-92
Schennach-Wolff R, Jäger M, Mayr A, Meyer S, Kühn KU, Klingberg S, Heuser I,
Klosterkötter J, Gastpar M, Schmitt A, Schlösser R, Schneider F, Gaebel W,
Seemüller F, Möller HJ, Riedel M (2011) Predictors of response and remission
in the acute treatment of first-episode schizophrenia patients - Is it all about
early response? Eur Neuropsychopharmacol 21:370-8
Schennach-Wolff R, Meyer S, Seemüller F, Jäger M, Schmauss M, Laux G, Pfeiffer
H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke
MR, Rüther E, Klingberg S, Gastpar M, Möller H-J, Riedel M (2011) Influencing
factors and predictors of early improvement in the acute treatment of
schizophrenia and schizophrenia spectrum disorder. J Psychiatr Res 45:163947
Schennach-Wolff R, Obermeier M, Seemüller F, Jäger M, Laux G, Pfeiffer H, Naber
D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke MR,
Rüther E, Klingberg S, Gastpar M, Möller HJ, Riedel M (2011) Evaluating
depressive symptoms and their impact on outcome in schizophrenia applying
the Calgary Depression Scale. Acta Psychiatr Scand 123:228-38
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Schennach-Wolff R, Seemüller F, Obermeier M, Messer T, Laux G, Pfeiffer H, Naber
D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W, Lemke MR,
Rüther E, Buchkremer G, Gastpar M, Jäger M, Möller HJ, Riedel M (2011)
Response and remission of subjective well-being in patients suffering from
schizophrenia spectrum disorders. Eur Psychiatry 26:284-92
Schilling C, Blum WF, Heuser I; Paslakis G, Wudy SA, Deuschle M (2011) Treatment
with antidepressants increases insulin-like growth factor-I in cerebrospinal
fluid. J Clin Psychopharmacol 31:390-2
Schipke CG, Heuser I, Peters O (2011) Antidepressants act on glial cells: SSRIs and
serotonin elicit astrocyte calcium signalling in the mouse prefrontal cortex.
Psychiatr Res 45:242-8
Schipke CG, Jessen F, Teipel S, Luckhaus C; Wiltfang J, Esselmann H, Frölich L,
Maier W, Rüther E, Heppner F, Prokop S, Heuser I, Peters O (2011) Longterm stability of Alzheimer’s disease biomarker proteins in cerebrospinal fluid.
J Alzheimers Dis 26:255-62
Schipke CG, Prokop S, Heppner FL Heuser I, Peters O (2011) Comparison of
immunosorbent assays for the quantification of biomarkers for Alzheimer’s
Disease in human cerebrospinal fluid. Dement Geriatr Cogn Disord 31:139-45
Teipel SJ, Peters O, Heuser I, Jessen F, Maier W, Froelich L, Arlt S, Hüll M, Gertz
HJ, Kornhuber J, Wiltfang J, Thome J, Rienhoff O, Meindl T, Hampel H,
Grothe M (2011) Atrophy outcomes in multicentre clinical trials on Alzheimer's
disease: effect of different processing and analysis approaches on sample
sizes. World J Biol Psychiatry 12 Suppl 1:109-13
2010
Bajbouj M, Merkl A, Schlaepfer TE, Frick C, Zobel A, Maier W, O’Keane V, Corcoran,
Adolfsson R, Trimble M, Rau H, Hoff H-J, Padberg F, Müller-Siecheneder,
Audenaert K, Van den Abbeele D, Matthews K, Christmas D, Eljamel S,
Heuser I (2010). Two-year outcome of Vagus Nerve Stimulation (VNS) in
treatment-resistant depression. J Clin Psychopharmacol 30:273-81
Jäger M, Riedel M, Obermeier M, Schennach-Wolff R, Seemüller F, Messer T, Laux
G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Kühn
K-U, Lemke MR, Rüther E, Klingberg S, Gastpar M, Bottlender R, Möller H-J
(2010) Time course of antipsychotic treatment response in schizophrenia:
Results from a naturalistic study in 280 patients. Schizophr Res 118:183-8
Jones L, Holmans PA, Hamshere ML, Harold D, … Heuser I, Peters O et al. (2010)
Genetic evidence implicates the immune system and cholesterol metabolism in
the aetiology of Alzheimer's disease. PLoS One Nov 15;5(11) (epub)
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14.05.2016
Klusmann V, Evers A, Schwarzer R, Schlattmann P, Reischies FM, Dimeo FC,
Heuser I (2010) Complex mental and physical activity in older women and
cognitive performance: A 6-month randomized controlled trial. J Gerontol. A
Biol Sci Med Sci 65:680-88
Kronenberg G, Gertz K, Baldinger T, Eckart S, Ji S, Yildirim F, Heuser I, Schröck H,
Hörtnagl H, Djoufack PC, Jüttner R, Hellweg R, Fink KB, Endres M (2010)
Impact of actin filament stabilization on adult hippocampal and olfactory bulb
neurogenesis. J Neurosci 30:3419-31
Lemke H, de Castro AG, Schlattmann P, Heuser I, Neu P (2010) Cerebrovascular
reactivity over time-course – from major depressive disorder to remission. J
Psychiatr Res 44:132-6
Lewczuk P, Kamrowski-Kruck H, Peters O, Heuser I, Jessen F, Popp J, Bürger K,
Hampel H, Frölich L, Wolf S, Prinz B, Jahn H, Luckhaus C, Perneczky R, Hüll
M, Schröder J, Kessler H, Pantel J, Gertz HJ, Klafki HW, Kölsch H, Reulbach
U, Esselmann H, Maler JM, Bibl M, Kornhuber J, Wiltfang J (2010) Soluble
amyloid precursor proteins in the cerebrospinal fluid as novel potential
biomarkers of Alzheimer's disease: a multicenter study. Mol Psychiatry 15:13845
Lewczuk P, Kornhuber J, Vanmechelen E, Peters O, Heuser I, Maier W, Jessen F,
Bürger K, Hampel H, Frölich L, Henn F, Falkai P, Rüther E, Jahn H, Luckhaus
C, Perneczky R, Schmidtke K, Schröder J, Kessler H, Pantel J, Gertz HJ,
Vanderstichele H, de Meyer G, Shapiro F, Wolf S, Bibl M, Wiltfang J (2010)
Amyloid beta peptides in plasma in early diagnosis of Alzheimer’s disease: A
multicenter study with multiplexing. Exp Neurol 223:366-70
Merkl A, Ammelburg N, Aust S, Roepke S, Reinecker H, Trahms L, Heuser I, Sander
T (2010) Processing of visual stimuli in borderline personality disorder: A
combined behavioural and magnetoencephalographic study. Int J
Psychophysiol 78:257-64
Paslakis G, Heuser I, Schweiger U, Deuschle M (2010) A single DEX/CRH test in
male drug-free depressed patients is associated with the clinical response to
treatment with fluoxetine. J Psychiatr Res 44:1154-7
Reichmann H, Deuschl G, Riedel O, Spottke A, Förstl H, Henn F, Heuser I, Oertel W,
Riederer P, Trenkwalder C, Dodel R, Wittchen H-U (2010) Die “German Study
on the Epidemiology of Parkinson’s Disease with Dementia” (GEPAD): mehr
als nur Parkinson. MMW Fortschr. Med. Originalien I (152. Jg.) S.1-6
Repantis D, Laisney O, Heuser I (2010) Acetylcholinesterase inhibitors and
memantine for neuroenhancement in healthy individuals: A systematic review.
Pharmacol Res 61:473-81
Repantis D, Schlattmann P, Laisney O, Heuser I (2010) Modafinil and
methylphenidate for neuroenhancement in healthy individuals: A systematic
review. Pharmacol Res 62:187-206
11
14.05.2016
Riedel M, Möller HJ, Obermeier M, Schennach-Wolff R, Bauer M, Adli M, Kronmüller
K, Nickel T, Brieger P, Laux G, Bender W, Heuser I, Zeiler J, Gaebel W,
Seemüller F (2010). Response and remission criteria in major depression – A
validation of current practive. J Psychiatr Res 44:1063-8
Riedel O, Heuser I, Klotsche J, Dodel R, Wittchen H-U (2010) Occurence risk and
structure of depression in Parkinsons disease with and without dementia:
Results from the GEPAD study. J Geriatr Psychiatry Neurol 23:27-34
Riedel O, Klotsche J, Spottke A, Deuschl G, Förstl H, Henn F, Heuser I, Oertel W,
Reichmann H, Riederer P, Trenkwalder C, Dodel R, Wittchen H-U (2010)
Frequency of dementia, depression, and other neuropsychiatric symptoms in
1,449 outpatients with Parkinson’s disease. J Neurol 257:1073-82
Ritter K, Röpke S, Merkl A, Heuser I, Fydrich T, Lammers CH (2010) [Comorbidity in
patients with narcissistic personality disorder in comparison to patients with
borderline personality disorder]. Komorbiditäten bei Patienten mit einer
Narzisstischen Persönlichkeitsstörung im Vergleich zu Patienten mit einer
Borderline-Persönlichkeitsstörung (Article in German) Psychother Psych Med
60:14-24
Roepke S, Ziegenhorn A, Kronsbein J, Merkl A, Bahri S, Lange J, Lübbert H,
Schweiger U, Heuser I, Lammers CH (2010) Incidence of polycystic ovaries
and androgen serum levels in women with borderline personality disorder. J
Psychiatr Res 44:847-52
Schennach-Wolff, Jäger M, Obermeier M, Schmauss M; Laux G, Pfeiffer H, Naber D,
Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Kühnj KU, Lemke MR,
Rüther E, Klingberg S, Gastpar M, Seemüller F, Möller HJ, Riedel M (2010)
Quality of life and subjective well-being in schizophrenia and schizophrenia
spectrum disorders: Valid predictors of symptomatic response and remission?
World J Biol Psychiatry 11:729-38
Schennach-Wolff R, Jäger M, Seemüller F, Obermeier M, Schmauss M, Laux G,
Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier
W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Möller HJ, Riedel M (2010)
Outcome of suicidal patients with schizophrenia: results from a naturalistic
study. Acta Psychiatr Scand 121:359-70
Schennach-Wolff R, Möller HJ, Jäger M, Seemüller F, Obermeier M, Messer T, Laux
G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier
W, Lemke MR, Rüther E, Klingberg S, Gastpar M, Riedel M (2010) A critical
analysis and discussion of the appropriateness of the schizophrenia
consensus
remission
criteria
in
clinical
pharmaceutical
trials.
Pharmacopsychiatry 43:245-51
12
14.05.2016
Schennach-Wolff R, Obermeier M, Seemüller F, Jäger M, Schmauss M, Laux G,
Pfeiffer H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier
W, Lemke MR, Rüther E, Buchkremer G, Gastpar M, Engel RR, Möller HJ,
Riedel M (2010) Does clinical judgement of baseline severity and changes in
psychopathology depend on the patient population? Results of a CGI and
PANSS linking analysis in a naturalistic study. J Clin Psychopharmacol
30:726-31
Schennach-Wolff R, Seemüller FH, Mayr A, Maier W, Klingberg S, Heuser I,
Klosterkötter J, Gastpar M, Häfner H, Sauer H, Schneider F, Gaebel W, Jäger
M, Möller HJ, Riedel M (2010) An early improvement threshold to predict
response and remission in first-episode schizophrenia. Br J Psychiatry
196:460-6
Seemüller F, Möller HJ, Obermeier M, Adli M, Bauer M, Kronmüller K, Holsboer F,
Brieger P, Laux G, Bender W, Heuser I, Zeiler J, Gaebel W, Schennach-Wolff
R, Henkel V, Riedel M (2010) Do efficacy and effectiveness samples differ in
antidepressant treatment outcome? An analysis of eligibility criteria in
randomized controlled trials. J Clin Psychiatry 71:1425-33
Seemüller F, Riedel M, Obermeier M, Bauer M, Adli M, Mundt C, Holsboer F, Brieger
P, Laux G, Bender W, Heuser I, Zeiler J, Gaebel W, Dichgans E, Bottländer R,
Musil R, Möller HJ (2010) Outcomes of 1014 naturalistic treated inpatients with
major depressive episode. Eur Neuropsychopharmacol 20:346-55
Teipel SJ, Ewers M, Wolf S, Jessen F, Kölsch H, Arlt S, Luckhaus C, Schönknecht P,
Schmidtke K, Heuser I, Frölich L, Ende G, Pantel J, Wiltfang J, Rakebrandt F,
Peters O, Born C, Kornhuber J, Hampel H (2010) Multicentre variability of
MRI-based medial temporal lobe volumetry in Alzheimer’s disease. Psychiatry
Res 182:244-50
Zeugmann S, Quante A, Heuser I, Schwarzer R, Anghelescu I (2010) Inflammatory
biomarkers in 70 depressed inpatients with and without the metabolic
syndrome. J Clin Psychiatry 71:1007-16
2009
Bajbouj M, Heuser I (2009) Stimulating the brain to treat depression. Exp Neurol
219:1
Blennow K, De Meyer G, Hansson O, Minthon L, Wallin A, Zetterberg H, Lewczuk P,
Vanderstichele H, Vanmechelen E, Kornhuber J, Wiltfang J; KND-Study
Group, Heuser I, Maier W, Luckhaus C, Rüther E, Hüll M, Jahn H, Gertz HJ,
Frölich L, Hampel H, Pernetzki R (2009) Evolution of Abeta42 and Abeta40
levels and Abeta42/Abeta40 ratio in plasma during progression of Alzheimer's
disease: a multicenter assessment. J Nutr Health Aging 13:205-8
Harold D, Abraham R, …, Heuser I … et al (2009) Genome-wide association study
identifies variants at CLU and PICALM associated with Alzheimer’s disease,
and shows evidence for additional susceptibility genes. Nat Genet 41:1088-93
13
14.05.2016
Henkel V, Seemüller F, Obermeier M, Adli M, Bauer M, Mundt C, Brieger P, Laux G,
Bender W, Heuser I, Zeiler J, Gaebel W, Mayer A, Möller H-J, Riedel M
(2009). Does early improvement triggered by antidepressants predict
response/remission? – Analysis of data from a naturalistic study on a large
sample of inpatients with major depression. J Affect Disord 115:439-49
Hornung OP, Regen F, Dorn H, Anghelescu I, Kathmann N, Schredl M, DankerHopfe H, Heuser I (2009). The effects of donepezil on postlearning sleep EEG
of healthy older adults. Pharmacopsychiatry 42:9-13
Jäger M, Riedel M, Schmauss M, Laux G, Pfeiffer H, Naber D, Gaebel W,
Klosterkoetter J, Heuser I, Kühn KU, Lemke MR, Rüther E, Buchkremer G,
Gastpar M, Bottlender R, Strauss A, Möller HJ (2009) Prediction of symptom
remission in Schizophrenia during inpatient treatment. World J Biol Psychiatry
10:426-34
Jäger M, Schmauss M, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W,
Klosterkötter J, Heuser I, Maier W, Lemke MR, Degner D, Buchkremer G,
Gastpar M, Möller HJ, Riedel M (2009) Early improvement as a predictor of
remission and response in schizophrenia: Results from a naturalistic study.
Eur Psychiatry 24:501-6
Klafki HW, Lewczuk P, Kamrowski-Kruck H, Maler JM, Müller K, Peters O, Heuser I,
Jessen F, Popp J, Frölich L, Wolf S, Prinz B, Luckhaus C, Schröder J, Pantel
J, Gertz HJ, Kölsch H, Müller BW, Esselmann H, Bibl M, Kornhuber J, Wiltfang
J (2009) Measurement of ERK 1/2 in CSF from Patients with Neuropsychiatric
Disorders and Evidence for the Presence of the Activated Form. J Alzheimer’s
Dis 18:613-22
Kölsch H, Jessen F, Wiltfang J, Lewczuk P, Dichgans M, Teipel SJ, Kornhuber J,
Frölich L, Heuser I, Peters O, Wiese B, Kaduszkiewicz H, van den Bussche H,
Hüll M, Kurz A, Rüther E, Henn FA, Maier W (2009) Association of SORL1
gene variants with Alzheimer's disease. Brain Research 1264:1-6
Kork F, Holthues J, Hellweg R, Jankowski V, Tepel M, Ohring R, Heuser I, Bierbrauer
J, Peters O, Schlattmann P, Zidek W, Jankowski J (2009) A possible new
diagnostic biomarker in early diagnosis of Alzheimer’s disease. Curr Alzheimer
Res 6:519-24
Kornhuber J, Schmidtke K, Frölich L, Perneczky R, Wolf S, Hampel H, Jessen F,
Heuser I, Peters O, Weih M, Jahn H, Luckhaus C, Hüll M, Gertz H-J, Schröder
J, Pantel J, Rienhoff O, Seuchter SA, Rüther E, Henn F, Maier W, Wiltfang J
(2009) Early and differential diagnosis of dementia and mild cognitive
impairment: design and cohort baseline characteristics of the German –
Dementia Competence Network. Dement Geriatr Cogn Disord 27:404-17
Kronenberg G, Kirste I, Inta D, Chourbaji S, Heuser I, Endres M, Gass P (2009)
Reduced hippocampal neurogenesis in the GR(+/-) genetic mouse model of
depression. Eur Arch Clin Neurosci 259:499-504
14
14.05.2016
Kronenberg G, Tebartz van Elst L, Regen F, Deuschle M, Heuser I, Colla M. (2009)
Reduced amygdala volume in newly admitted psychiatric in-patients with
unipolar major depression. J Psychiatr Res 43:1112-7
Merkl A, Heuser I, Bajbouj M (2009) Antidepressant electroconvulsive therapy:
Mechanism of action, recent advances and limitations. Exp Neurol 219:20-6
Schennach-Wolff R, Jäger M, Seemüller F, Obermeier M, Messer T, Laux G, Pfeiffer
H, Naber D, Schmidt LG, Gaebel W, Huff W, Heuser I, Maier W, Lemke MR,
Rüther E, Buchkremer G, Gastpar M, Möller HJ, Riedel M. (2009) Defining
and predicting functional outcome in schizophrenia and schizophrenia
spectrum disorders. Schizophr Res 113:210-7
Schennach-Wolff R, Jäger M, Seemüller F, Obermeier M, Messer T, Laux G, Pfeiffer
H, Naber D, Schmidt LG, Gaebel W, Klosterkötter J, Heuser I, Maier W,
Lemke MR, Rüther E, Klingberg S, Gastpar M, Möller HJ, Riedel M. (2009)
Attitude towards adherence in patients with schizophrenia at discharge. J
Psychiatr Res 43:1294-1301
Seemüller F, Riedel M, Obermeier M, Bauer M, Adli M, Mundt C, Holsboer F,
Marneros A, Laux G, Bender W, Heuser I, Zeiler J, Jäger M, Henkel V, Möller
HJ (2009) The controversial link between antidepressants and suicidality risks
in adults: data from a naturalistic study on a large sample of in-patients with a
major depressive episode. Int J Neuropsychopharmacol 12:181-9
Weber-Hamann B, Blum WF, Kratzsch J, Gilles M, Heuser I, Deuschle M (2009)
Insulin-like growth factor-I (IGF-I) serum concentrations in depressed patients:
relationship to saliva cortisol and changes during antidepressant treatment.
Pharmacopsychiatry 42:23-8
Ziegenhorn AA, Röpke S, Schommer NC, Merkl A, Danker-Hopfe H, Perschel FH,
Heuser I, Anghelescu IG, Lammers CH (2009) Clonidine improves
hyperarousal in borderline personality disorder with or without comorbid
posttraumatic stress disorder: a randomized, double-blind, placebo-controlled
trial. J Clin Psychpharmacol 29:170-3
2008
Colla M, Ende G, Alm B, Deuschle M, Heuser I, Kronenberg G (2008) Cognitive MR
spectroscopy of anterior cingulate cortex in ADHD: elevated choline signal
correlates with slowed hit reaction times. J Psychiatr Res 42:587-95
De Castro AG, Bajbouj M, Schlattmann P, Lemke H, Heuser I, Neu P (2008)
Cerebrovascular reactivity in depressed patients without vascular risk factors.
J Psychiatr Res 42:78-82
Hellweg R, Ziegenhorn A, Heuser I, Deuschle M (2008) Serum concentrations of
nerve growth factor and brain-derived neurotrophic factor in depressed
patients before and after antidepressant treatment. Pharmacopsychiatry
41:66-71
15
14.05.2016
Hornung OP, Regen F, Danker-Hopfe H, Heuser I, Anghelescu I (2008) Sleep-related
memory consolidation in depression: an emerging field of research. Depress
Anxiety 25:E163-5
Hornung OP, Regen F, Warnstedt C, Anghelescu I, Danker-Hopfe H, Heuser I,
Lammers CH (2008) Declarative and procedural memory consolidation during
sleep in patients with borderline personality disorder. J Psychiatr Res 42:653-8
Jäger M, Messer T, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W,
Klosterkötter J, Heuser I, Maier W, Lemke MR, Rüther E, Buchkremer G,
Gastpar M, Riedel M, Bottlender R, Strauss A, Möller HJ (2008) Standardized
remission criteria in schizophrenia: descriptive validity and comparability with
previously used outcome measures. Pharmacopsychiatry 41:190-5
Jäger M, Riedel M, Schmauss M, Pfeiffer H, Laux G, Naber D, Gaebel W, Huff W,
Schmidt LG, Heuser I, Buchkremer G, Kühn KU, Rüther E, Hoff P, Gastpar M,
Bottlender R, Strauss A, Möller HJ (2008) Depression during an acute episode
of schizophrenia or schizophreniform disorder and its impact on treatment
response. Psychiatry Res 158:297-305
Jakob F, Brakemeier EL, Schommer NC, Quante A, Merkl A, Danker-Hopfe H,
Anghelescu I, Heuser I, Bajbouj M (2008) Ultrahigh frequency repetitive
transcranial magnetic stimulation in unipolar depression. J Clin
Psychopharmacol 28:474-6
Kölsch H, Jessen F, Wiltfang J, Lewczuk P, Dichgans M, Kornhuber J, Frölich L,
Heuser I, Peters O, Schulz JB, Schwab SG, Maier W (2008) Influence of
SORL1 gene variants: association with CSF amyloid-beta products in probable
Alzheimer's disease. Neurosci Lett 440:68-71
Kronenberg G, Ende G, Alm B, Deuschle M, Heuser I, Colla M (2008) Increased NAA
and reduced choline levels in the anterior cingulum following chronic
methylphenidate: a spectroscopic test-retest study in adult ADHD. Eur Arch
Psychiatry Clin Neurosci 258:446-50
Lewitzka U, Müller-Oerlinghausen B, Felber W, Brunner J, Hawellek B, Rujescu D,
Ising M, Lauterbach E, Broocks A, Bondy B, Rao ML, Frahnert C, Heuser I,
Hohagen F, Maier W, Bronisch T (2008) Is MAO-B activity in platelets
associated with the occurrence of suicidality and behavioural personality traits
in depressed patients? Acta Psychiatr Scand 117:41-9
Möller HJ, Riedel M, Jäger M, Wickelmaier F, Maier W, Kühn KU, Buchkremer G,
Heuser I, Klosterkötter J, Gastpar M, Braus DF, Schlösser R, Schneider F,
Ohmann C, Riesbeck, Gaebel W (2008) Short-term treatment with risperidone
or haloperidol in first-episode schizophrenia: 8-week results of a randomized
controlled trial within the German Research Network on Schizophrenia. Int J
Neuropsychopharmacol 11:985-97
16
14.05.2016
Riedel O, Klotsche J, Spottke A, Deuschl G, Foerstl H, Henn F, Heuser I, Oertel W,
Reichmann H, Riederer P, Trenkwalder C, Dodel R, Wittchen HU (2008)
Cognitive impairment in 873 patients with idiopathic Parkinson’s Disease:
Results from the German Study on Epidemiology of Parkinson’s Disease with
Dementia (GEPAD). J Neurol 255:255-64
Roepke S, Merkl A, Dams A, Ziegenhorn A, Anghelescu IG, Heuser I, Lammers CH
(2008) Preliminary evidence of improvement of depressive symptoms but not
impulsivity in Cluster B personality disorder patients treated with Quetiapine:
an open label trial. Pharmacopsychiatry 41:176-81
Schlaepfer TE, Frick C, Zobel A, Maier W, Heuser I, Bajbouj M, O'Keane V, Corcoran
C, Adolfsson R, Trimble M, Rau H, Hoff HJ, Padberg F, Müller-Siecheneder F,
Audenaert K, Van den Abbeele D, Matthews K, Christmas D, Stanga Z,
Hasdemir M (2008) Vagus nerve stimulation for depression: efficacy and
safety in a European study. Psychol Med 38:651-61
Seemüller F, Riedel M, Wickelmaier F, Adli M, Mundt C, Marneros A, Laux G, Bender
W, Heuser I, Zeiler J, Gaebel W, Jäger M, Möller HJ, Henkel V (2008) Atypical
symptoms in hospitalised patients with major depressive episode: frequency,
clinical characteristics, and internal validity. J Affect Disord 108:271-8
2007
Dams A, Schommer N, Röpke S, Heuser I, Lammers CH (2007) Skill training and the
post-treatment efficacy of dialectic behavior therapy six month after discharge
of the hospital. Psychother Psychosom Med Psychol 57:19-24
Halbreich U, Backstrom T, Eriksson E, O’Brien S, Calil H, Ceskova E, Dennerstein L,
Douki S, Freeman E, Genazzani A, Heuser I, Kadri N, Rapkin A, Steiner M,
Wittchen HU, Yonkers K (2007) Clinical diagnostic critieria for premenstrual
syndrome and guidelines for their quantification for research studies. Gynecol
Endocrinol 23:123-30
Jäger M, Riedel M, Messer T, Laux G, Pfeiffer H, Naber D, Schmidt LG, Gaebel W,
Huff W, Heuser I, Kühn KW, Lemke MR, Rüther E, Buchkremer G, Gastpar M,
Bottlender R, Strauss A, Möller HJ (2007) Psychopathological characteristics
and treatment response of first episode compared with multiple episode
schizophrenic disorders. Eur Arch Psychiatry Clin Neurosci 257:47-53
King JA, Colla M, Brass M, Heuser I, von Cramon DY (2007) Inefficient cognitive
control in adult ADHD: evidence from a trial-by-trial Stroop test and cued task
switching performance. Behav Brain Funct 3:42
Weber-Hamann B, Kratzsch J, Kopf D, Lederbogen F, Gilles M, Heuser I, Deuschle
M (2007) Resistin and adiponectin in major depression: the association with
free cortisol and effects of antidepressant treatment. J Psychiatr Res 41:34450
17
14.05.2016
2006
Bajbouj M, Danker-Hopfe H, Heuser I, Anghelescu I (2006) Long-term outcome of
vagus nerve stimulation in rapid-cycling bipolar disorder. J Clin Psychiatry
67:837-8
Bajbouj M, Lang UE, Niehaus L, Hellen FE, Heuser I, Neu P (2006). Effects of right
unilateral electroconvulsive therapy on motor cortical excitability in depressive
patients. J Psychiatr Res 40:322-7
Bajbouj M, Lisanby SH, Lang UE, Danker-Hopfe H, Heuser I, Neu P (2006) Evidence
for impaired cortical inhibition in patients with unipolar major depression. Biol
Psychiatry. 59:395-400
Danker-Hopfe H, Hornung O, Regen F, Hansen ML, Albrecht N, Heuser I (2006)
Subjective sleep quality in noncomplaining elderly subjects: results of a followup study. Anthropol Anz. 64:369-76
Froelich L, Heuser I, Wellek S (2006) Zur klinischen Relevanz von CholinesteraseInhibitoren bei Alzheimer Krankheit: Eine klinische und biometrische Kritik der
AD2000-Studie. psychoneuro 32:32-7
Hornung OP, Regen F, Schredl M, Heuser I, Danker-Hopfe H (2006) Manipulating
REM sleep in older adults by selective REM sleep deprivation and
physiological as well as pharmacological REM sleep augmentation methods.
Exp Neurol 197:486-94
Lauterbach E, Brunner J, Hawellek B, Lewitzka U, Ising M, Bondy B, Rao ML,
Frahnert C, Rujescu D, Müller-Oerlinghausen B, Schley J, Heuser I, Maier W,
Hohagen F, Felber W, Bronisch T (2006) Platelet 5-HT2A receptor binding and
tryptophan availability in depression are not associated with recent history of
suicide attempts but with personality traits characteristic for suicidal behavior. J
Affect Disord 91:57-62
Neu
P, Schwertfeger N, Schlattmann P, Heuser I, Berman RM (2006)
Cerebrovascular reactivity following administration of mirtazapine in healthy
probands – a randomized, placebo controlled double-blind clinical study. J
Psychiatr Res 40:349-52
Schredl M, Hornung O, Regen F, Albrecht N, Danker-Hopfe H, Heuser I (2006) The
effect of donepezil on sleep in elderly, healthy persons: a double-blind
placebo-controlled study. Pharmacopsychiatry. 39:205-8
Schwertfeger N, Neu P, Schlattmann P, Lemke H, Heuser I, Bajbouj M (2006)
Cerebrovascular reactivity over time course in healthy subjects. J Neurol Sci
249:135-9
18
14.05.2016
Weber-Hamann B, Gilles M, Lederbogen F, Heuser I, Deuschle M (2006) Improved
insulin sensitivity in 80 nondiabetic patients with MDD after clinical remission in
a double-blind, randomized trial of amitriptyline and paroxetine. J Clin
Psychiatry 67:1856-61
Weber-Hamann B, Werner M, Hentschel F, Bindeballe N, Lederbogen F, Deuschle
M, Heuser I (2006) Metabolic changes in elderly patients with major
depression: evidence for increased accumulation of visceral fat at follow-up.
Psychoneuroendocrinology. 31:347-54
2005
Bajbouj M, Heuser I (2005) [Vagus nerve stimulation, repetitive transcranial magnetic
stimulation, and electroconvulsive therapy in the treatment of depressive
disorders]. (Article in German) Nervenarzt 76:28-35
Bajbouj M, Lang UE, Neu P, Heuser I (2005) Therapeutic brain stimulation and
cortical excitability in depressed patients. Am J Psychiatry 162:2192-3.
Bronisch T, Brunner J, Bondy B, Rujescu D., Bishof G, Heuser I, MuellerOerlinghausen B, Hawellek B, Maier W, Rao ML, Felber W, Lewitzka U, Oehler
J, Broocks A, Hohagen F, Lauterbach E (2005) A multicenter study about
neurobiology of suicidal behaviour: design, development, and preliminary
results. Arch Suicide Res 9:19-26
Deuschle M, Sander P, Herpfer I, Fiebich BL, Heuser I, Lieb K (2005) Substance P in
serum and cerebrospinal fluid of depressed patients: no effect of
antidepressant treatment. Psychiatry Res 136:1-6
Gilles M, Deuschle M, Kellner S, Shams M, Krumm B, Härtter S, Heuser I, Hiemke C
(2005) Paroxetine serum concentrations in depressed patients and response
to treatment. Pharmacopsychiatry 38:118-21
Hornung OP, Danker-Hopfe H, Heuser I (2005) Age-related changes in sleep and
memory: commonalities and interrelationships. Exp Gerontol 40:279-85
Kronenberg G, Berger P, Tauber RF, Bandelow B, Henkel V, Heuser I (2005)
Randomized, double-blind study of SR142801 (Osanetant). A novel
neurokinin-3 (NK3) receptor antagonist in panic disorder with pre- and
posttreatment
cholecystokinin
tetrapeptide
(CCK-4)
challenges.
Pharmacopsychiatry 38:24-9
Lauterbach E, Ahrens B, Felber W, Oerlinghausen BM, Kilb B, Bischof G, Heuser I,
Werner P, Hawellek B, Maier W, Lewitzka U, Pogarell O, Hegerl U, Bronisch T,
Richter K, Niklewski G, Broocks A, Hohagen F (2005) Suicide prevention by
lithium SUPLI – challenges of a multi-center prospective study. Arch Suicide
Res 9:27-34
Neu P, Heuser I, Bajbouj M (2005) Cerebral blood flow during vagus nerve
stimulation – a transcranial Doppler study. Neuropsychobiology 51:265-8
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Regen F, Merkl A, Heuser I, Dettling M, Anghelescu I (2005) Diabetes and
depression. Dtsch Med Wochenschr 130:1097-102
Weber-Hamann B, Kopf D, Lederbogen F, Gilles M, Heuser I, Colla M, Deuschle M
(2005) Activity of the hypothalamus-pituitary-adrenal system and oral glucose
tolerance in depressed patients. Neuroendocrinology 81:200-4
2004
Deuschle M, Kniest A, Niemann H, Erb-Bies N, Colla M, Hamann B, Heuser I (2004)
Impaired declarative memory in depressed patients is slow to recover: clinical
experience. Pharmacopsychiatry 37:147-51
Deuschle M, Krumm B, Bindeballe N, Colla M, Hamann B, Lederbogen F, Gilles M,
Heuser I (2004) Open-label non-randomized versus double-blind randomized
antidepressive treatment: what are the advantages of clinical decision over
randomization? Pharmacopsychiatry 37:299-302
Deuschle M, Luppa P, Gilles M, Hamann B, Heuser I (2004) Antidepressant
treatment and dehydroepidandrosterone sulfate: different effects of
amitriptyline and paroxetine. Neuropsychobiology 50:252-6
Froelich L, Gertz HJ, Heun R, Heuser I, Jendroska K, Kornhuber J, Kurz A, MuellerThomsen T, Ries F, Waechtler C, Metz M, Goebel C (2004) Donepezil for
Alzheimer’s disease in clinical practice – the DONALD study. Dement Geriatr
Cogn Disord 18:37-43
Godemann F, Koffroth C, Neu P, Heuser I (2004) Why does vertigo become chronic
after neuropathia vestibularis? Psychosom Med 66:783-7
Heuser I, Dettling M (2004) [Health economic aspects of medical care and
therapeutic options for schizophrenic and depressive patients in Germany].
Medizinische
Versorgung
und
therapeutische
Optionen
unter
gesundheitsökonomischen Aspekten bei psychiatrischen Patienten in
Deutschland am Beispiel schizophrener und depressiver Störungen (Article in
German). Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
47:745-50
Kopf D, Westphal S, Luley CW, Ritter S, Gilles M, Weber-Hamann B, Lederbogen F,
Lehnert H, Henn F, Heuser I, Deuschle M (2004) Lipid metabolism and insulin
resistance in depressed patients: significance of weight, hypercortisolism and
antidepressant treatment. J Clin Psychopharmacol 24:527-31
Niedermaier N, Bohrer E, Schulte K, Schlattmann P, Heuser I (2004) Prevention and
treatment of poststroke depression with mirtazapine in patients with acute
stroke. J Clin Psychiatry 65:1619-23
Schmitt B, Bernhardt T, Möller HJ, Heuser I, Froelich L (2004) Combination therapy in
Alzheimer’s disease: a review of current evidence. CNS drugs 18:827-44
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2003
Colla M, Ende G, Bohrer M, Deuschle M, Kronenberg G, Henn F, Heuser I (2003)
MR spectroscopy in Alzheimer’s disease: gender differences in probabilistic
learning capacity. Neurobiol Aging 24:545-52
Deuschle M, Bode L, Schnitzler P, Meyding-Lamadé U, Plesch A, Ludwig H,
Hamann B, Heuser I (2003) Hypothalamic-pituaitary-adrenal (HPA) system
activity in depression and infection with Borna disease virus and Chlamydia
pneumoniae. Mol Psychiatry 8:469-70
Deuschle M, Hamann B, Meichel C, Krumm B, Lederbogen F, Kniest A, Colla M,
Heuser I (2003) Antidepressive treatment with amitriptyline and paroxetine:
effects upon saliva cortisol concentrations. J Clin Psychopharmacol 23:201-5
Deuschle M, Lecei O, Stalla GK, Landgraf R, Hamann B, Lederbogen F, Uhr M,
Luppa P, Maras A, Colla M, Heuser I (2003) Steroid synthesis inhibition with
ketoconazole and its effect upon the regulation of the hypothalamus-pituitaryadrenal system in healthy humans. Neuropsychopharmacology 28:379-83
Deuschle M, Luppa P, Hamann B, Nonell A, Heuser I (2003) Increased concentration of corticosteroid-binding globulin due to antidepressant treatment with
amitriptyline, but not paroxetine. J Psychiatr Res 37:85-7
Heuser I (2003) Depression: Ein kardialer Risikofaktor. DNP 4:36-7
Heuser I (2003) MCI Combi: Die aktuelle Therapiestudie im Kompetenznetz
Demenzen. Psychoneuro 29:16-7
Heuser I (2003) Prevention of dementias: state of the art. (Article in German) Dtsch
Med Wochenschr 128:421-2
Heuser I, Lammers CH (2003) Stress and the brain. Neurobiol Aging 24 Suppl 1:S6976
Hock C, Maddalena A, Rasching A, Müller-Spahn F, Eschweiler G, Hager K, Heuser
I, Hampel H, Müller-Thomsen T, Oertel W, Wienrich M, Signorelli A, GonzalezAgosti, C, Nitsch RM (2003) Treatment with the selective muscarinic m1
agonist talsaclidine decreases cerebrospinal fluid levels of A beta 42 in
patients with Alzheimer’s disease. Amyloid 10:1-6
Lederbogen F, Gernoth C, Hamann B, Kniest A, Heuser I, Deuschle M (2003)
Circadian blood pressure regulation in hospitalized depressed patients and
non-depressed comparison subjects. Blood Press Monit 8:71-6
Lederbogen F, Horer E, Hellweg R, Heuser I, Deuschle M (2003) Platelet counts in
depressed patients treated with amitriptyline or paroxetine. Eur Psychiatry
18:89-91
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Lederbogen F, Schredl M, Weber-Hamann B, Kniest A, Heuser I (2003) Effect of
ambulatory blood pressure measurement on sleep in patients with a major
depressive episode. Blood Press Monit 8:187-90
2002
Henning O, Niedermaier N, Kniest A, Heuser I, Deuschle M (2002) Amitriptyline and
paroxetine: effects upon peripheral nervous system (PNS). J Clin
Psychopharmacol 22:229-30
Heuser I (2002) Depression, endocrinologically a syndrome of premature aging?
Maturitas 41 Suppl 1:S19-23
Heuser I (2002) Therapeutische Strategien bei Demenz. Neuro Psych Nachrichten
Juli 2002, S. 13
Heuser I, Reischies F (2002) Die Altersdepression erkennen und behandeln. Extracta
Geriatrica 1:10-4
Schredl M, Kronenberg G, Nonell P, Heuser I (2002) Sleep quality in patients with
panic disorder: relationship to nocturnal panic attacks. Somnologie 6:149-53
Weber-Hamann B, Hentschel F, Kniest A, Deuschle M, Colla M, Lederbogen F,
Heuser I (2002) Hypercortisolemic depression is associated with increased
intra-abdominal fat. Psychosom Med 64:274-7
2001
Heuser I (2001) Demenzen: Medikamentöse Therapie - aktueller Stand und Ausblick.
Notabene Medici 7:294
Kniest A, Wiesenberg C, Weber B, Colla M, Heuser I, Deuschle M (2001) The
glutamate antagonist riluzole and ist effects upon basal and stress-induces
activity of the human hypothalamus-pituitary-adrenocortical (HPA) system in
elderly subjects. Neuropsychobiology 43:91-5
Kronenberg G, Schredl M, Fiedler K, Heuser I (2001) In healthy volunteers
responses to challenge with cholecystokinin tetrapeptide differ between
administration during REM and delta sleep. Depress Anxiety 14:141-4
Lederbogen F, Gernoth C, Weber B, Colla M, Kniest A, Heuser I, Deuschle M (2001)
Antidepressive treatment with amitriptyline and paroxetine: comparable effects
upon heart rate variability. J Clin Psychopharmacol 21:238-9
Lederbogen F, Gilles M, Maras A, Hamann B, Colla M, Heuser I, Deuschle M (2001)
Increased platelet aggregability in major depression? Psychiatry Res 102:25561
22
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Lederbogen F, Weber B, Colla M, Heuser I, Deuschle M, Dempfle CE (2001)
Antidepressant treatment and global tests of coagulation and fibrinolysis. J Clin
Psychiatry 62:130
Schredl M, Kronenberg G, Nonnell P, Heuser I (2001) Dream recall, nightmare
frequency, and nocturnal panic attacks in patients with panic disorder. J Nerv
Ment Dis 189:559-62
Schredl M, Weber B, Leins M-L, Heuser I (2001) Donepezil-induces REM sleep
augmentation enhances memory performance in elderly, healthy persons. Exp
Gerontol 36:353-61
BOOK CHAPTERS:
Heuser, I (2009) Psychopharmaka zur Leistungsverbesserung, Tagungsdokumentation Der steuerbare Mensch? Über Einblicke und Eingriffe in unser
Gehirn. Jahrestagung des Deutschen Ethikrates 2009, pp. 49-55
Heuser I, Anghelescu I (2008) Antidementiva. In: Holsboer F, Gründer G, Benkert O
(Eds.) Handbuch der Psychopharmakotherapie. Springer Verlag Heidelberg,
pp. 643-65
Anghelescu I, Heuser I, (2008) Psychostimulanzien. In: Holsboer F, Gründer G,
Benkert O (Eds.) Handbuch der Psychopharmakotherapie. Springer Verlag
Heidelberg, pp. 701-8
Colla
M, Heuser I (2008) Aufmerksamkeitsdefizit-/Hyperaktivitätsstörung im
Erwachsenenalter. In: Holsboer F, Gründer G, Benkert O (Eds.) Handbuch der
Psychopharmakotherapie. Springer Verlag Heidelberg, pp. 1023-32
Anghelescu I, Lange-Asschenfeldt, Heuser I, (2008) Pharmakotherapie
psychiatrischer Notfallsituationen. In: Holsboer F, Gründer G, Benkert O (Eds.)
Handbuch der Psychopharmakotherapie. Springer Verlag Heidelberg, pp.
1049-58
Schommer NC, Heuser I (2007) DEX-CRH Test. In: Fink G (Ed.) Encyclopedia of
Stress, Four-Volume Set, Second Edition. Elsevier, pp. 784-7
Schommer NC, Heuser I (2006) Stress Systems in Aging – Cognitions and Dementia.
In: Arnetz BB, Ekman R (Ed.) Stress in Health and Disease. Wiley VCH, pp.
366-83
Heuser I, Anghelescu I (2003) Kognitives Altern und Demenz-Erkrankungen. UNIMED Verlag Bremen, First Edition
Anghelescu I, Heuser I (2003) Psychostimulants. In: Rosenthal W, Offermanns S
(Eds.) Encyclopedic reference of molecular pharmacology. Springer Verlag
Heidelberg, pp. 775-81
23
14.05.2016
Heuser I (2002) Psychosomatik. In: Ralf Schwarzer, Matthias Jerusalem und
Hannelore Weber (Eds.) Gesundheitspsychologie von A bis Z. Hogrefe Verlag
Göttingen, pp. 420-3
Heuser I (2001) Depression, metabolisches Syndrom und kardiovaskuläre Morbidität.
In: Rohde A und Riecher-Rössler A (Eds.) Psychische Erkrankungen bei
Frauen. S. Roderer Verlag, Regensburg, pp. 329-31
24
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