Univ. Prof. Dr. Michael Gnant 1 Originalarbeiten -1- Muehlbacher F, Steininger R, Laengle F, Sautner T, Gnant M, Goetzinger P, Piza F, Popow T OKT 3 immunoprophylaxis in human liver transplantation Transplant P 1989; 21: 2253-4 2 IF: 1,096 Sautner T, Graninger G, Gnant M, Jantsch H Adjuvante Therapie einer Pseudomonaspneumonie und -sepsis bei einer immunsupprimierten Patientin nach orthotoper Lebertransplantation mit einer IgM-angereicherten Immunglobulinloesung und Fibronectin-angereichertem Acta Chir Austriaca 1989; 6: 304-5 Serum IF: 0,000 3 Muehlbacher F, Steininger R, Laengle F, Hamilton G, Sautner T, Gnant M, Goetzinger P, Piza F, Popow T Prophylaxis with OKT 3 for liver transplantation Transplant P 1989; 21 Suppl 2: 25-30 4 IF: 1,096 Gnant M, Sautner T, Muehlbacher F, Steininger R, Laengle F, Piza F Professionelle Organgewinnung als Vorraussetzung zum Erreichen der notwendigen Transplantationsfrequenz: Erfahrungen mit der Organspende am Transplantationszentrum Wien Wiener Klin Wochenschr 1989; 23: 824-8 5 IF: 0,245 Laengle F, Gnant M, Sautner T, Muehlbacher F, Kretschmer G, Traindl O, Kovarik J, Derfler K, Balcke B, Steger H, Hajek A, Piza F Erfahrungen und klinische Ergebnisse nach 99 Verwandtennierentransplantationen Wiener Klin Wochenschr 1989; 5: 148-51 6 IF: 0,216 Muehlbacher F, Gnant M, Auinger M, Steininger R, Klauser R, Prager R, Karnel F Pancreatic venous drainage to the portal vein: A new method in human pancreatic transplantation Transplant P 1990; 22: 636-7 7 IF: 0,987 Steininger R, Fuegger R, Hackl W, Hamilton G, Herbst F, Laengle F, Gnant M, Rogy M, Sautner T, Schulz F, Muehlbacher F Immediate graft function after OLT clears endotoxins Transplant P 1990; 22: 1544-6 8 IF: 0,987 Funovics J, Gnant M, Piza F Zur Neubewertung der Indikation zur Lebertransplantation Leber-Magen-Darm 1990; 1: 7-11 9 IF: 0,227 Laengle F, Gnant M, Sautner T, Muehlbacher F, Watzinger U, Derfler K, Manker M, Piza F Homologe Saphenavenen als AV-Shunt zur Hämodialyse: Ein Vergleich zu konventionellen Methoden Angio Arch 1990; 19: 171-3 IF: 0,000 2 Univ. Prof. Dr. Michael Gnant 10 Originalarbeiten -2- Gnant M Aspects and prospects of organ procurement: The Vienna experience ETCO Newsl 1990; 1: 7-10 11 IF: 0,000 Gnant M, Schoental E, Banhegyi C, Steininger R, Sautner T, Goetzinger P, Wamser P, Zekert F, Muehlbacher F The impact of serum lipid parameters on the diagnosis of acute and chronic rejection after orthotopic liver transplantation Transplant Proc 1991; 23: 1434-5 12 IF: 1,064 Muehlbacher F, Huk I, Steininger R, Gnant M, Goetzinger P, Wamser P, Banhegyi C, Piza F Is orthotopic liver transplantation a feasable treatment for secondary cancer of the liver? Transplant P 1991; 23: 1567-8 13 IF: 1,064 Stockenhuber F, Gnant M, Apperl A, Steininger R, Sautner T, Balcke P, Muehlbacher F Soluble interleukin-2 receptor in liver transplant recipients Transplant P 1991; 23:1417-8 14 IF: 1,064 Roka R, Niederle B, Gnant M, Laengle F, Hausmaninger C, Neuhold N Derzeitiger Therapieplan beim differenzierten Schilddrüsenkarzinom Chirurg 1991; 62: 518-23 15 IF: 0,392 Sautner T, Goetzinger P, Wamser P, Gnant M, Steininger R, Muehlbacher F Impact of donor age on graft function in 1180 consecutive kidney recipients Transplant P 1991; 23: 2598-601 16 IF: 1,064 Gnant M, Wamser P, Goetzinger P, Sautner T, Steininger R, Muehlbacher F The impact of presumed consent law and decentralized organ procurement system on organ donation: quadruplication of number of organ donors Transplant P 1991; 23: 2685-6 17 IF: 1,064 Gnant M, Rosenmayr A, Wamser P, Goetzinger P, Sautner T, Steininger R, Banhegyi C, Muehlbacher F Prenephrectomy tissue typing using donor lymph node cells: A reliable and safe way of shortening cadaver kidney ischemia time Transplant P 1991; 23: 2683-4 18 IF: 1,064 Gnant M, Blijham G, Schemper M, Reiner A, Reiner G, Spona J, Reynders M, Schutte B, van Asche C, Steger G, Jakesz R Der prognostische Stellenwert der Flowzytometrie beim Mammakarzinom: 10-Jahres-Ergebnisse einer randomisierten Studie Acta chir Austriaca 1991; 2: 43-8 IF: 0,000 2 Univ. Prof. Dr. Michael Gnant 19 Originalarbeiten -3- Steininger R, Muehlbacher F, Längle F, Gnant M, Sautner T, Goetzinger P, Walgram M, Penner E, Radaszkiewicz T Erfahrungen mit der Lebertransplantation beim Hepatitis-B-Antigen positiver Leberzirrhose Wien Klin Wochschr 1991; 19: 573-6 20 IF: 0,243 Banhegyi C, Sautner T, Gnant M, Goetzinger P, Wamser P, Muehlbacher F Transplantation of shipped full-house kidneys versus local poorly matched grafts - does a shorter cold ischemic time outweigh a worse match? Transplant P 1991; 23: 2610-1 21 IF: 1,064 Steininger R, Muehlbacher F, Hamilton G, Laengle F, Gnant M, Popow T, Sautner T, Goetzinger P, Wamser P, Stockenhuber F, Mirza D, Piza F Comparison of CyA, OKT3, and ATG immunoprophylaxis in human liver transplantation Transplant P 1991; 23: 2269-71 22 IF: 1,064 Jakesz R, Hausmaninger H, Depisch D, Kubista E, Samonigg H, Steindorfer P, Schemper M, Gnant M, Kolb R, Krauß K, Manfreda D, Stierer M, Michlmayr G, Fridrik M, Dadak C, Hofbauer F, Horvath W, Zielinski C, Wette V, Oppitz P, Duenser M, Lenzhofer R, Mueller Ludwig H; Adler A, Aiginger P, Bauer D, Bauerndorfer T,bei Beinhauer A, Boeckl O, Brunhofer A, Abgeschlossene undL,derzeit laufende adjuvante Therapieprotokolle Patienten mit operablem Mammakarzinom Acta chir Austriaca 1991; 2: 63-9 23 IF: 0,000 Hamilton G, Prettenhofer M, Zommer A, Hofbauer S, Goetzinger P, Gnant M, Függer R Intraoperative course and prognostic significance of Endotoxin, Tumor necrosis factor-alpha and Interleukin-6 in liver transplant recipients Immunobiology 1991; 182: 425-39 24 IF: 1,576 Sautner T, Gnant M, Goetzinger P, Wamser P, Steininger R, Muehlbacher F Cadaveric kidney donation beyond the age of 60 - a comparative analysis of 1180 grafts from different donor age groups Tranplant Int 1992; 5 Suppl 1: S47-S50 25 IF: 0,907 Sautner T, Gnant M, Banhegyi C, Wamser P, Goetzinger P, Steininger R, Muehlbacher F Risk factors for development of panel reactive antibodies and their impact on transplantation outcome in 909 kidney grafts Transplant Int 1992; 5 Suppl 1; S116-S120 26 IF: 0,907 Gnant M, Blijham G, Reiner A, Reiner G, Reynders M, Schutte B, van Asche C, Steger G, Jakesz R DNA ploidy and other results of DNA Flow cytometry as prognostic factors in operable breast cancer: 10 year results of a randomized study Eur J Cancer 1992; 28: 711-6 27 IF: 2,191 Gnant M, Sautner T, Wamser P, Goetzinger P, Rosenmayr A, Muehlbacher F A reliable way of shortening cadaver kidney ischemia time: Prenephrectomy tissue typing using donor lymph node cells Tranplant Int 1992; 5 Suppl 1: S722-S724 IF: 0,907 2 Univ. Prof. Dr. Michael Gnant 28 Originalarbeiten -4- Gnant M, Sautner T, Rosenmayr A, Muehlbacher F Repeated HLA mis-match in multiple kidney transplantation - Preliminary results of 146 retransplantations in the cyclosporine era Transplant P 1992; 24: 2466-2468 29 IF: 1,125 Gnant M, Seifert M, Jakesz R, Adler A, Mittlboeck M, Sevelda P Breast cancer and timing of surgery during menstrual cycle: A 5-year analysis of 385 premenopausal women Int J Cancer 1992; 52: 707-712 30 IF: 2,917 Fuegger R, Klimann S, Gnant M, Herbst F, Schulz F, Fritsch A Laparoskopische Cholecystektomie - Auswertung einer prospektiven Beobachtungsstudie Wien Klin Wochenschr 1992; 104/20: 640-3 31 IF: 0,196 Neuhold N, Laengle F, Gnant M, Hollenstein U, Niederle B Relationship of CD15 immunoreactivity and prognosis in sporadic medullary thyroid carcinoma J Cancer Res Clin 1992; 118: 629-634 32 IF: 1,820 Fuegger R, Klimann S, Gnant M, Schulz F, Fritsch A Gallengangsverletzungen bei laparoskopischer Cholecystektomie Helv Chir Acta 1992; 59: 571-571 33 IF: 0,046 Sautner T, Gnant M, Banhegyi C, Wamser P, Goetzinger P, Steininger R, Hajek-Rosenmayr A, Muehlbacher F Risikofaktoren für die Entstehung lymphozytotoxischer Antikörper und deren Einfluß auf die Organfunktion nach Nierentransplantation Acta chir Austriaca 1992; 24: 354-8 34 IF: 0,000 Fuegger R, Herbst F, Gnant M, Goetzinger P, Sautner T, Windberger U, Siegl H, Losert U, Fritsch A Die experimentelle laparoskopische Sigmaresektion Min Inv Chir 1992; 1: 167-8 35 IF: 0,576 Gnant M, Sautner T, Rosenmayr A, Muehlbacher F Tolerance induction in human kidney retransplantation: Impact of repeated HLA mismatches in 156 second renal grafts Transplant P 1993; 25: 319-321 36 IF: 1,125 Stockenhuber F, Kramer G, Pec M, Scentkiraly A, Gnant M, Steininger R, Balcke P, Muehlbacher F Circulating ICAM-1: Novel parameter of renal graft rejection Transplant P 1993; 25: 919-920 IF: 1,125 2 Univ. Prof. Dr. Michael Gnant 37 Originalarbeiten -5- Gruenberger T, Gnant M, Sautner T, Hoebarth K, Steininger R, Hofbauer J, Muehlbacher F Impact of vesicoureteral reflux on graft survival in renal transplantation Transplant P 1993; 25: 1058-1059 38 IF: 1,125 Steger G, Mader R, Gnant M, Marosi C, Lenz K, Jakesz R GM-CSF in the treatment of a patient with severe methotrexate intoxication J Intern Med 1993; 233: 499-502 39 IF: 1,453 Gnant M, Blijham G, Schemper M, Reiner A, Reiner G, Spona J, Reynders M, Schutte B, van Asche C, Steger G, Jakesz R Aneuploidy Fraction but not DNA Index is important for the prognosis of patients with stage I and II breast cancer - 10 year results Ann Oncol 1993; 4: 643-650 40 IF: 2,064 Hamilton G, Vogel S, Fuegger R, Gnant M Mechanisms of tumor necrosis factor-a and interleukin-6 induction during human liver transplantation Mediat Inflamm 1993; 2: 303-307 41 IF: 0,870 Wamser P, Goetzinger P, Gnant M, Sautner T, Steininger R, Muehlbacher F What do intensive care unit personell think about organ donation? Opinion poll amongst transplant centers Transplant P 1993; 25:3122-3 42 IF: 1,125 Fuegger R, Herbst F, Gnant M, Sautner T, Goetzinger P, Windberger U, Siegl H, Losert U, Fritsch A Laparoskopische Kolonchirurgie - vom Experiment zu ersten klinischen Erfahrungen Wien Klin Wochenschr 1993; 105: 544-548 43 IF: 0,268 Wamser P, Goetzinger P, Steininger R, Gnant M, Sautner T, Muehlbacher F Discontinuing of a permanent information and education program among donors ICUs leads to a 50% decrease of organ donor rates Transplant P 1993; 25: 2988-9 44 IF: 1,125 Gnant M, Wamser P, Barlan M, Muehlbacher F Impact of donor cause of death on renal graft function - a multivariate analysis of 1545 kidney transplants Transplant P 1993; 25: 3102-3 45 IF: 1,125 Goetzinger P, Gnant M, Hochstoeger E, Jakesz R The potential impact of Tamoxifen in Breast Cancer Prevention Onkologie 1993; 16: 297-303 IF: 0,545 2 Univ. Prof. Dr. Michael Gnant 46 Originalarbeiten -6- Steger GG, Mader RM, Djavanmard MP, Gnant M, Locker G, Marosi C, Rainer H, Jakesz R Double modulation of 5-flourouracil by high-dose leucovorin and interferon a2b in advanced colorectal cancer: A phase I and a phase II study of weekly administration J Cancer Res Clin Oncol 1994; 120: 314-318 47 IF: 1,820 Mader RM, Steger GG, Rizovski B, Sieder AE, Locker G, Gnant M, Jakesz R, Rainer H Pharmacokinetics of rac-leucovorin versus [S]-leucovorin in patients with advanced gastrointestinal cancer Brit J Clin Pharmac 1994; 37: 243-248 48 IF: 1,922 Wamser P, Goetzinger P, Barlan M, Gnant M, Hoelzenbein T, Watschinger B, Muehlbacher F Reasons for 50% reduction in the number of organ donors within 2 years - opinion poll amongst all ICUs of a tranplant centre Transplant Int 1994; 7 [Suppl 1]: S668-671 48A IF: 0,907 Wamser P, Goetzinger P, Barlan M, Gnant M, Hoelzenbein T, Watschinger B, Muehlbacher F Reasons for 50% reduction in the number of organ donors within 2 years - opinion poll amongst all ICUs of a tranplant centre Eurotransplant Newsletter 1994; 116: 6-9 49 IF: 0,000 Rudas M, Gnant M, Mittlboeck M, Neumayer R, Kummer A, Jakesz R, Reiner G, Reiner A Thymidine labeling index and Ki-67 growth fraction in breast cancer: Comparison and correlation with prognosis Breast Cancer Res Tr 1994; 32: 165-175 50 IF: 2,479 Fiegl M, Tueni C, Schenk T, Jakesz R, Gnant M, Reiner A, Rudas M, Pirc-Danoewinata H, Marosi C, Huber H, Drach J Interphase cytogenetics reveals a high incidence of aneuploidy and intra-tumour heterogeneity in breast cancer Brit J Cancer 1995; 72: 51-55 51 IF: 3,449 Locker G, Simonitsch I, Mader RM, Warlamides E, Gnant M, Jakesz R, Rainer H, Steger G Cutaneous Side Effects in breast cancer patients treated with cytostatic polychemotherapy and rh GM-CSF: Immune henomena or drug toxicity ? (cutaneous reations to GM-CSF in breast cancer) Breast Cancer Res Tr 1995; 34: 213-9 52 IF: 2,879 Jakesz R, Gnant M Die Bedeutung der Lymphadenektomie bei Patienten mit colorectalem Carcinom Acta Chir Aust 1995; 9: 99 53 IF: 0,000 Gnant M Abdominalchirurgie in der geriatrischen Onkologie Onko-logisch 1995; 3: 12-3 IF: 0,000 2 Univ. Prof. Dr. Michael Gnant 54 Originalarbeiten -7- Tschugguel W, Blaicher A, Klamer L, Felfernig M, Jungling G, Kurz M, Gnant M, Zimpfer M Platelet disorders in uraemia before and after haemodialysis under the influence of low dose apirin Thromb Res 1995; 80: 225-33 55 IF: 1,443 Gruenberger T, Gorlitzer M, Soliman T, Rudas M, Mittlboeck M, Goetzinger P, Gnant M, Reiner A, Teleky B, Seitz W, Jakesz R Kann man einer hochselektionierten Patientinnengruppe nach Brusterhaltender Therapie wegen Mammakarzinoms die postoperative Nachbestrahlung ersparen? Acta Chir Aust 1995; 27: 269-73 56 IF: 0,000 Berlakovich G, Imhof M, Karner-Hanusch J, Goetzinger P, Gollackner B, Gnant M, Hanelt S, Laufer G, Muehlbacher F, Steininger R The importance of the effect of underlying disease on rejection outcomes following orthotopic liver transplantation Transplantation 1996; 61: 554-60 57 IF: 3,544 Taucher S, Gnant M, Djavanmard M, Kandioler D, Goetzinger P, Rudas M, Steger G, Jakesz R Neoadjuvant chemotherapy enables breast conserving surgery in patients with very large breast cancers Onkologie 1996; 19: 242-6 58 IF: 0,451 Kandioler D, Dekan G, End A, Pasching E, Buchmayer H, Gnant M, Langmann F, Mannhalter C, Eckersberger F, Wolner E Molecular genetic differentiation between primary lung cancers and lung metastases of other tumors J Thorac Cardiov Surg 1996; 111: 827-31 59 IF: 2,874 Early Breast Cancer Trialists' Collaborative Group Ovarian ablation in early breast cancer: overview of the randomised trials Lancet 1996; 348: 1189-1196 60 IF: 17,948 Gruenberger T, Windhager T, Gnant M, Mittlboeck M, Steininger R, Herbst F, Muehlbacher F Tumor recurrence after oLTX Transplant Int 1996; 9S1: S151-4 61 IF: 1,522 Helbich T, Becherer A, Trattnig S, Leitha T, Kelkar P, Seifert, Gnant M, Staudenherz A, Rudas M, Wolf G, Mostbeck GH Differentiation of benign and malignant breast lesions: MR imaging versus Tc-99m sestamibi Scintimammography Radiology 1997; 202: 421-9 62 IF: 4,698 Rudas M, Neumayer R, Gnant M, Mittlboeck, Jakesz R, Reiner A p53 protein expression, cell proliferation and steroid hormone receptors in ductal and lobular in situ carcinomas of the breast Eur J Cancer 1997; 33: 39-44 IF: 2,743 2 Univ. Prof. Dr. Michael Gnant 63 Originalarbeiten Jakesz R, Gnant M, Schmid M, Smonigg H, Steindorfer P, Hausmaninger H, Sevelda P, Depisch D, Tausch C, Reiner G, Renner K, Stierer M, Pilz E, Jatzko G, Hofbauer F, Fridrik M, Schennach W, Dadak C, Haid A, Kusbista E, Scholz R, Sagaster P, Winter R,und Lenzhofer R laufende adjuvante Therapieprotokolle bei Patientinnen mit operablem Abgeschlossene derzeit Mammakarzinom (II) Acta Chirurgica Austriaca 1997; 29: 62-67 64 -8- IF: 0,000 Steger G, Gnant M, Djavanmard M, Mader R, Jakesz R, Pierce W, deKernion J, Figlin R, Belldegrun A The in vitro effects of interleukin-12 upon tumor-infiltrating lymphocytes derived from renal cell carcinoma J Cancer Res Clin Oncol 1997; 123: 317-324 65 IF: 1,459 Müller M, Mader RM, Steiner B, Steger GG, Jansen B, Gnant M, Helbich T, Jakesz R, Eichler HG, Blöchl-Daum B 5-fluorouracil kinetics in the interstital tumor space: clinical response in breast cancer patients Cancer Res 1997; 57: 2598-601 66 IF: 8,426 Reiner A, Rudas M, Neumayer R, Gnant M, Mittlboeck M, Jakesz R Protein-p53-Expression, Cell proliferation and steroid hormone receptors in Ductal Carcinoma in situ of the breast Acta Chir Aust 1997; 29: 123-125 67 IF: 0,000 Gruenberger T, Gorlitzer M, Soliman T, Rudas M, Mittlboeck M, Gnant M, Reiner A, Teleky B, Seitz W, Jakesz R It is possible to omit postoperative irradiation in a highly selected group of elderly breast cancer patients? Breast Cancer Res Tr 1998; 50: 37-46 68 IF: 2,430 Helbich T, Rudas M, Haitel A, Kohlberger P, Thurnher M, Gnant M, Wunderbaldinger P, Wolf G, Mostbeck G Evaluation of needle size for breast biopsy: Comparison of 14-, 16, and 18-gauge biopsy needles Am J Roentgenol 1998; 171: 59-63 69 IF: 2,332 Jakesz R, Samonigg H, Gnant M, Kubista E, Steindorfer P, Hausmaninger H, Sevelda P, Tschurtschenthaler B, Fridrik M, Stierer M, Kolb R, Steger G, and the Austrian Breast Cancer Study Group Very low dose adjuvant chemotherapy in steroid receptor negative stage I breast cancer patients Eur J Cancer 1998; 34:66-70 70 IF: 2,743 Early Breast Cancer Trialists' Collaborative Group Tamoxifen for early breast cancer: an overview of the randomised trials The Lancet 1998; 351: 1451-1467 71 IF: 16,135 Peck-Radosavljevic M, Pidlich J, Bergmann M, Ferenci P, Seelos C, Wichlas M, Lipinski E, Gnant M, Gangl A, Muehlbacher F and the Liver Transplant Oncology Group Preoperative TNM-classification is a better prognostic indicator for recurrence of hepatocellular carcinoma after liver transplantation then albumin mRNA in peripheral blood J Hepatol 1998; 28: 497-503 IF: 3,189 2 Univ. Prof. Dr. Michael Gnant 72 Originalarbeiten -9- Cosentini E, Sautner T, Gnant M, Winkelbauer F, Teleky B, Jakesz R Outcomes of surgical, Percutaneous endoscopic, and percutaneous radiologic gastrostomies Arch Surg 1998; 133: 1076-1083 73 IF: 2,526 Wu P, Berger A, Huang J, Gnant M, Turner E, Alexander HR, Libutti S In vivo tumors that overexpress Endothelial Monocyte-Activatin Polypeptide II demonstrate upregulation of tumor necrosis factor receptor p55 on tumor neovasculature Surg Forum 1998; 49: 436-438 74 IF: 0,000 Early Breast Cancer Trialists' Collaborative Group Polychemotherapy for early breast cancer: an overview of the randomised trials The Lancet 1998; 351: 1451-1467 75 IF: 11,793 Jakesz R, Taucher S, Gnant M, Gebhard B, Kandioler D, Rudas M, Djavanmard M, Steger G Neoadjuvante Chemotherapie bei Patientinnen mit Mammakarzinom Zentralbl Chir 1998; 123 (S5) 147-150 76 IF: 0,425 Götzinger P, Gebhard B, Gnant M, Rudas M, Reiner A, Jakesz R Die Wertigkeit der Stanzbiopsie in der Diagnostik palpabler Brusttumoren. Eine prospektive Analyse an 150 Patienten. Chirurg 1998; 69: 1068-71 77 IF: 0,932 Friedl J, Stift A, Berlakovich G, Taucher S, Gnant M, Steininger R, Mühlbacher F Haemophilus parainfluenza liver abscess after successful liver transplantation J Clin Microbiol 1998: 818-9 78 IF: 3,579 Pokorny H, Puhalla H, Krenn CG, Soliman T, Langer F, Gruenberger T, Gollackner B, Schindl M, Wamser P, Goetzinger P, Sautner T, Gnant M, Steininger R, Muehlbacher F Management of organ donation following trauma in conventional heart-beating donor and non-heartbeating donor situations Trauma Care 1999; 9: 30-32 79 IF: 0,000 Locker GJ, Steger GG, Gnant M, Steiner B, Simonitsch I, Krainer M, Budinsky A, Brodowitz T, Jakesz R, Zielinski CC Induction of Immunomediated Diseases by Recombinant Human Granulocyte-Macrophage ColonyStimulating Factor During Cancer Treatment? J Immunotherapy 1999; 22: 85-9 80 IF: 3,059 Gnant M, Puhlmann M, Alexander HR, Bartlett DL Systemic Administration of a Recombinant Vaccinia Virus Expressing the Cytosine Deaminase Gene and Subsequent Treatment with 5-Fluorocytosine Leads to Tumor-specific Gene Expression and Prolongation of Survival in Mice Cancer Res 1999; 59: 3396-3403 IF: 8,614 2 Univ. Prof. Dr. Michael Gnant 81 Originalarbeiten - 10 - Jakesz R, Gebhard B, Gnant M, Taucher S Indikationen und Kontraindikationen für brusterhaltende chirurgische Therapie Chirurg 1999; 70: 394-399 82 IF: 0,932 Gnant M, Puhlmann M, Bartlett DL, Alexander HR Regional versus Systemic Delivery of Recombinant Vaccinia Virus as Suicide Gene Therapy for Murine Liver Metastases Ann Surg 1999; 230: 352-361 83 IF: 5,987 Wenzel C, Schmidinger M, Locker GJ, Taucher S, Gnant M, Jakesz R, Steger GG Clinical phase II-evaluation of neoadjuvant, cytostatic combination chemotherapy with docetaxel and epidoxorubicin in female breast cancer patients (T1-4, N0-2, M0) Wien Klin Wochenschr 1999; 111: 843-850 84 IF: 0,588 Puhlmann M, Gnant M, Brown C, Alexander H, Bartlett D Thymidine kinase-Deleted Vaccinia Virus Expressing Purine Nucleoside Phosphorylase as a Vector for Tumor-Directed Gene Therapy Hum Gene Ther 1999; 10: 649-657 85 IF: 6,796 Kucera E, Speiser P, Gnant M, Szabo L, Samonigg H, Hausmaninger H, Mittlboeck M, Fridrik M, Seifert M, Kubista E, Reiner A, Zeillinger R, Jakesz R, and the ABCSG Prognostic significance of mutations in the p53 gene, particularly in the Zinc-binding domains, in lymph node- and steroid receptor positive breast cancer patients Eur J Cancer 1999; 35: 398-405 86 IF: 2,725 Gnant M, Noll L, Irvine K, Puhlmann M, Terrill R, Alexander R, Bartlett D Tumor-specific gene delivery using recombinant vaccinia virus in a lapine model of liver metastases J Nat Cancer Inst 1999; 91:1744-50 87 IF: 14,159 Jakesz R, Hausmaninger H, Haider K, Kubista E, Samonigg H, Gnant M, Manfreda D, Tschurtschenthaler G, Kolb R, Stierer M, Fridrik M, Mlineritsch B, Mittlboeck M, Steger G, and the Austrian Breast Cancer Study Group Randomized trial of low-dose chemotherapy added to tamoxifen in patients with receptor-positive and lymph node-positive breast cancer J Clin Oncol 1999; 17: 1701-1709 88 IF: 8,773 Gnant M, Noll LA, Terrill RE, Wu PC, Berger AC, Nguyen HQ, Lans TE, Flynn BM, Libutti SK, Bartlett DL, Alexander HR Isolated hepatic perfusion for lapine liver metastases: Impact of hyperthermia on permeability of tumor neovasculature Surgery 1999; 126: 890-899 89 IF: 2,456 Wu P, Alexander H, Huang J, Hwu P, Gnant M, Berger A, Turner E, Wilson O, Libutti S In vivo sensitivity of human melanoma to tumor necrosis factor (TNF) alpha is determined by tumor production of the novel cytokine Endothelial-Monocyte Activating Polypeptide II (EMAPII) Cancer Res 1999; 59: 205-12 IF: 8,614 2 Univ. Prof. Dr. Michael Gnant 90 Originalarbeiten - 11 - Gnant M, Berger A, Huang J, Puhlmann M, Wu P, Merino M, Bartlett D, Alexander R, Libutti S Sensitiziation of tumor necrosis factor alpha (TNF) resistant human melanoma by tumor specific in vivo transfer of the gene endcoding for Endothelial Monocyte Activating Peptide II (EMAP-II) using recombinant Vaccinia virus Cancer Res 1999; 59:4668-74 IF: 8,614 91 Gnant M Highlights vom ASCO 99 - Mammakarzinom adjuvant Onkologisch 1999; 7: 9-11 92 IF: 0,000 Gebhard B, Schuetz G, Ecker R, Steiner GE, Rudas M, Gnant M, Oehler R Class I major histocompatibiliy complex expression in human breast cancer correlates with nuclear localization of the 90 kDa heat shock protein Anticancer Res 1999; 19: 5293-5297 93 IF: 1,375 Gnant M, Turner E, Alexander HR Effects of hyperthermia and tumor necrosis factor on inflammatory cytokine secretion and procoagulant activity in endocelial cells Cytokine 2000; 12; 339-347 94 IF: 2,490 Kandioler-Eckersberger D, Ludwig C, Rudas M, Kappel S, Janschek E, Wenzel C, Schlagbauer-Wadl H, Mittlboeck M, Gnant M, Steger G, Jakesz R TP53 Mutation and p53 Overexpression for Prediction of Response to Neoadjuvant Treatment in Breast Cancer Patients Clin Cancer Res 2000; 6: 50-56 95 IF: 5,076 Puhlmann M, Brown C, Gnant M, Huang J, Libutti S, Alexander H, Bartlett D Vaccinia as a vector for tumor directed gene therapy: Biodistribution of a thymidine kinase deleted mutant Cancer Gene Ther 2000; 7: 66-73 96 IF: 4,151 Bachleitner-Hofmann T, Gnant M Die chirurgische Axilladissektion: Technischer Standard oder obsolete Methode? Zbl Chir 2000; 125: 822-829 97 IF: 0,302 Berger AC, Feldman AL, Gnant M, Kruger EA, Sim BKL, Hewitt S, Figg WD, Alexander HR, Libutti SK The angiogenesis inhibitor Endostatin does not affect murine cutaneous wound healing J Surg Res 2000; 91: 26-31 98 IF: 1,674 Early Breast Cancer Trialists' Collaborative Group Favourable and unfavourable effects on long-term survival of radiotherapy for eraly breast cancer: an overview of the randomised trials Lancet 2000; 355:1757-1770 IF: 13,251 2 Univ. Prof. Dr. Michael Gnant 99 Originalarbeiten - 12 - Bachleitner-Hofmann T, Gnant M Die axilläre Lymphknotendissektion in der Therapie des Mammakarzinoms Acta Chirurgica Austriaca 2000; 32: 119-123 100 IF: 0,000 Stift A, Friedl J, Brostjan C, Dubsky P, Schueller G, Bachleitner-Hofmann T, Radelbauer K, Jakesz R, Gnant M Adoptive zelluläre Immuntherapie Acta Chirurgica Austriaca 2000; 32:255-259 101 IF: 0,000 Berger AC, Alexander HR, Wu PC, Tang G, Gnant M, Mixon A, Turner E, Libutti SK Tumor necrosis factor receptor I (p55) is upregulated on endothelial cells by exposure to the tumor derived cytokine endothelial monocyte activating peptide II (EMAP-II) Cytokine 2000; 12:992-1000 102 IF: 2,490 Friedl J, Stift A, Paolini P, Roth E, Steger GG, Mader R, Jakesz R, Gnant M Tumor antigen pulsed dendritic cells enhance the cytolytic activity of tumor infiltrating lymphocytes in human hepatocellular cancer Cancer Biother Radio 2000; 15: 477-86 103 IF: 1,574 Bachleitner-Hofmann T, Gnant M Gentherapie - Tor zur Zukunft? Acta Chirurgica Austriaca 2000; 32: 264-269 104 IF: 0,000 Lans TE, Bartlett DL, Libutti SK, Gnant M, Liewehr DJ, Venzon DJ, Turner EM, Alexander HR Role of Tumor Necrosis Factor (TNF) on Toxicity and Cytokine Production after Isolated Hepatic Perfusion Clin Cancer Res 2001; 7: 784-790 105 IF: 5,991 Gnant M Chirurgische Onkologie an der Jahrtausendwende - Editorial Acta Chirurgica Austriaca 2000; 32: 249-250 106 IF: 0,000 Gebhard B, Gnant M, Schutz G, Roka S, Weigel G, Kandioler D, Taucher S, Grunberger T, Roth E, Jakesz R, Spittler A Different transendothelial migration behaviour pattern of blood monocytes derived from patients with benign and malignant diseases of the breast Anticancer Res 2000; 4599-604 107 IF: 1,416 Schueller G, Paolini P, Friedl J, Stift A, Dubsky P, Bachleitner-Hofmann T, Jakesz R, Gnant M Heat Treatment of Hepatocellular Carcinoma Cells: Increased Levels of Heat Shock Proteins 70 and 90 Correlate with Cellular Necrosis Anticancer Res 2001; 21: 295-300 IF: 1,416 2 Univ. Prof. Dr. Michael Gnant 108 Originalarbeiten - 13 - Locker GJ, Wenzel C, Schmidinger M, Gnant M, Marosi C, Jakesz R, Zielinski CC, Steger G Unexpected severe myelotoxicity of gemcitabine in pretreated breast cancer patients Anticancer Drugs 2001; 12: 209-12 109 IF: 2,013 Birner P, Oberhuber G, Stani J, Reithofer C, Samonigg H, Hausmaninger H, Kubista E, Kwasny W, Kandioler-Eckersberger D, Gnant M, Jakesz R Evaluation of the United States food and drug administration-approved scoring and test system of HER-2 protein expression in breast cancer Clin Cancer Res 2001; 7: 1669-1675 110 IF: 5,991 Janschek E, Kandioler-Eckersberger D, Ludwig C, Kappel S, Wolf B, Taucher S, Rudas M, Gnant M, Jakesz R Contralateral breast cancer: molecular differentiation between metastasis and second primary cancer Br Cancer Res Treat 2001; 67:1-8 111 IF: 2,866 Latinovic L, Heinze G, Birner P, Samonigg H, Hausmaninger H, Kubista E, Kwasny W, Gnant M, Jakesz R, Oberhuber G, for the Austrian Breast and Colorectal Cancer Study Group Prognostic Relevance of three histological grading methods in breast cancer Int J Oncol 2001; 19: 1271-1277 112 IF: 2,330 Schmidinger M, Wenzel C, Locker GJ, Muehlbacher F, Steininger R, Gnant M, Crevenna R, Budinsky AC Pilot study with pegylated liposomal doxorubicin for advanced or unresectable hepatocellular carcinoma Br J Cancer 2001; 85: 1850-1852 113 IF: 3,942 Cole BF, Gelber RD, Gelber S, Coates AS, Goldhirsch A, for the EBCTCG Polychemotherapy for early breast cancer: an overview of the randomised trials with quality-adjusted survival analysis Lancet 1998; 358: 277-286 114 IF: 11,793 Wenzel C, Locker GJ, Schmidinger M, Rudas M, Taucher S, Gnant MFX, Jakesz R, Steger GG Combined analysis of two phase II trials in patients wirh primary and advanced breast cancer with epidoxorubicin and docetaxel + G-CSF Anti-Cancer Drugs 2002; 13: 67-74 115 IF: 2,013 Bachleitner-Hofmann T, Stift A, Friedl J, Pfragner R, Radelbauer K, Dubsky P, Schueller G, Benkoe T, Niederle B, Brostjan C, Jakesz R, Gnant M Stimulation of autologous antitumor T-cell responses against medullary thyroid carcinoma using tumor lysate-pulsed dendritic cells J Clin Endoc Metab 2002; 87: 1098-1104 116 IF: 5,447 Wenzel C, Locker G, Pluschnig U, Zielinski C, Rudas M, Oberhuber G, Gnant M, Taucher S, Jakesz R, Steger G Phase I/II trial of weekly epidoxorubicin and docetaxel (wED) in the neoadjuvant and palliative treatment of patients with breast cancer Cancer Chemother Pharmacol 2002; 50: 155-159 IF: 2,170 2 Univ. Prof. Dr. Michael Gnant 117 Originalarbeiten - 14 - Schindl M, Schoppmann SF, Samonigg H, Hausmaninger H, Kwasny W, Gnant M, Jakesz R, Kubista E Birner P, Oberhuber G Overexpression of hypoxia inducible factor (HIF) 1alpha ias associated with an unfavourable prognosis in lymph node-positive breast cancer Clin Cancer Res 2002; 8: 1931-1837 IF: 5,991 118 Jakesz R, Hausmaninger H, Samonigg H, Kubista E, Gnant M, Menzel C, Bauernhofer T, Seifert M, Haider K, Steger G, Mlineritsch B, Steindorfer P, Kwasny W, Fridrik M, Wette V, for the Austrian Breast Cancer Study Group A Randomized Trial of Tamoxifen and Goserelin versus CMF: Evidence for the Superiority of Treatment with Endocrine Blockade in Premenopausal Patients with Hormone-Responsive Breast (ABCSG Trial1-9 5) JCancer Clin Oncol 2002; 20: IF: 9,868 119 Friedl J, Puhlmann M, Bartlett DL, Libutti SK, Turner EM, Gnant M, Alexander HR Induction of permeability across endothelial cel monolayers by tumor necrosis factor (TNF) accurs via a tue factor-dependent mechanism: relationship between the procoagulant and permeability effects of TNF. Blood 2002; 100: 1334-1339 IF: 9,631 120 Pfarl G, Helbich TH, Riedl CC, Wagner T, Gnant M, Rudas M, Liberman L Stereotactic 11-gauge vacuum assisted breast biopsy: a validation study AJR 2002; 179: 1503-1507 121 IF: 2,424 Bachleitner-Hofmann T, Gebhard B, Rudas M, Gnant M, Taucher S, Kandioler D, Janschek E, Dubsky P, Roka S, Jakesz R Pattern of hormone receptor status of secondary contralateral breast cancers in patients receiving adjuvant tamoxifen Clin Cancer Res 2002; 8: 3427-3432 122 IF: 5,991 Dubsky PC, Gnant M, Taucher S, Roka S, Kandioler D, Pichler-Gebhard B, Agstner I, Seifert M, Sevelda P, Jakesz R Young age as independent adverse prognostic factor in premenopausal patients with breast cancer Clin Breast Cancer 2002; 13: 67-74 123 IF: 0,000 Stift A, Friedl J, Brostjan C, Dubsky P, Bachleitner-Hofmann T, Jakesz R, Gnant M Dendritic cell based vaccination in solid organ cancer J Clin Oncol 2003; 21: 135-142 124 IF: 10,864 Taucher S, Rudas M, Gnant M, Dubsky P, Roka S, Bachleitner-Hofmann T, Kandioler D, Wenzel C, Steger G, Mittlboeck M, Jakesz R Sequential steroid hormone receptor measurements in primary breast cancer with and without intervening primary chemotherapy Endo Rel Cancer 2003; 10: 91-98 125 IF: 8,894 Stift A, Friedl J, Dubsky P, Bachleitner-Hofmann T, Benkoe T, Brostjan C, Jakesz R, Gnant M In vivo induction of dendritic cell-mediated cytotoxicity against allogeneic pancreatic carcinoma cells Int J Oncol 2003; 22: 651-660 IF: 2,536 2 Univ. Prof. Dr. Michael Gnant Originalarbeiten - 15 - 126 Schmid M, Jakesz R, Samonigg H, Kubista E, Gnant M, Menzel C, Seifert M, Haider K, Taucher S, Mlineritsch B, Steindorfer P, Kwasny W, Fridrik M, wette H, Hausmaninger H, for the Austrian Breast Cancer Study Group Tamoxifen versus Tamoxifen plus Aminoglutethimid as Adjuvant Treatment in Postmenopausal breast Cancer Patients wirth Hormone-responsive Disease: A Randomized Trial of 2,021 Patients Trial 6) 21: 984-990 J(ABCSG Clin Oncol 2003; IF: 10,864 127 Schoppmann S, Schindl M, Bayer G, Aumayr K, Dienes J, Horvat R, Rudas M, Gnant M, Jakesz R, Birner Overexpression of Id-1 is associated with poor clinical outcome in node negative breast cancer Int J Cancer 2003; 104: 677-682 128 IF: 4,375 Schueller G, Stift A, Friedl J, Dugsky P, Bachleitner-Hofmann T, Benkoe T, Jakesz R, Gnant M Hyperthermia improves cellular immune response to human hepatocellular carcinoma subsequent fo co-culture with tumor lysate pulsed dendritic cells Int J Oncol 2003; 22: 1397-1402 129 IF: 2,536 Taucher S, Salat A, Gnant M, Kwasny W, Mlineritsch B, Menzel RC, Schmid M, Smola MG, Stierer M, Tausch C, Galid A, Jakesz R, for the Austrian Breast and colorectal Cancer Study Group Impact of pretreatment thrombocytosis on survival in primary breast cancer Thromb Haemost 2003; 89: 1098-1106 130 IF: 4,950 Heinze G, Gnant M, Schemper M Exact log rank tests for unequal follow-up Biometrics 2003; 59: 1151-1157 131 IF: 1,324 Taucher S, Gnant M, Jakesz R Preventive mastectomy in patients at breast cancer risk due to genetic alterations in the BRCA1 and BRCA2 gene Langenbecks Arch Surg 2003; 388: 3-8 132 IF: 0,921 Ploner F, Jakesz R, Hausmaninger H, Kolb R, Stierer M, Fridrik M, Steindorfer P, Gnant M, Haider K, Mlineritsch B, Tschurtschenthaler G, Steger G, Seifert M, Kubista E, Samonigg H, and the Austrian Breast and Colorectal Cancer Study Group Randomized trial: One cyle of anthracycline-containing adjuvant chemotherapy compared with six cycles of CMF treatment in node-positive, hormone receptor-negative breast cancer patients Onkologie 2003: 26: 115-119 133 IF: 1,154 Future Directions in the treatment of Breast Cancer: Celllular interventions using dendritic cells Gnant M, Dubsky P, Stift A, Friedl J, Steger G, Jakesz R, Zielinski C Breast Canc Res Treatm 2003; 81 134 IF: 3,310 Brostjan C, Bayer A, Zommer A, Gornikiewicz S, Roka S, Benkö T, Yaghubian R, Jakesz R, Steger G, Gnant M, Friedl J, Stift A Monitoring of circulating angiogenetic factors in dendritic cell-based cancer immunotherapy Cancer 2003; 98: 2291-30 IF: 4,017 2 Univ. Prof. Dr. Michael Gnant 135 Originalarbeiten Taucher S, Rudas M, Gnant M, Dubsky P, Sporn E, Roka S, Bachleitner-Hofmann T, Fitzal F, Kandioler D, Wenzel C, Steger G, Draxler W, Mittlboeck M, Jakesz R The impact of progesterone receptor in prediction of complete pathological response to preoperative chemotherapy in primary breast cancer patients European Surgery 2003; 136 - 16 - IF: 0,000 Gnant M Pancreatic Cancer Treatment European Surgery 2003; 35: 342-343 137 IF: 0,000 Taucher S, Rudas M, Mader R, Gnant M, Dubsky P, Bachleitner-Hofmann T, Roka S, Fitzal F, Kandioler D, Sporn E, Friedl J, Mittlboeck M, Jakesz R Do we need HER2/neu testing for all patients with primary breast carcinoma? Cancer 2003; 98: 2547-2553 138 IF: 4,017 Beslija S, Bonneterre J, Burstein H, Gnant M, Goodwin P, Heinemann V, Jassem J, Köstler W, Krainer M, Menard S, Miles D, Petruzelka L, Possinger K, Schmid P, Stadtmauer E, Stockler M, Van Belle S, Vogel C, Wilcken N, Wiltschke C, Zielinski C, Zwierzina Hon Medical Treatment of Metastatic Breast Cancer Consensus Br Canc Res Treatm 2003; 81: S1-S7 139 IF: 2,964 Taucher S, Rudas M, Mader R, Gnant M, Sporn E, Dubsky P, Roka S, Bachleitner-Hofmann T, Fitzal F, Kandioler D, Wenzel C, Steger G, Mittlboeck M, Jakesz R Influence of neoadjuvant therapy with epirubicin an ddocetaxel on the expression of HER2/neu in patients with breast cancer Breast Canc Res Treatm 2003; 82: 207-213 140 IF: 2,964 Jakesz R, Hausmaninger H, Samonigg H, Gnant M, Kubista E, Depisch D, Kolb R, Mlineritsch B, Mischinger HJ, Menzel RC, Steindorfer P, Kwasny W, Tausch C, Stierer M, Seifert M, and the Austrian Breast & Colorectal Cancer Study Group (ABCSG) Significant Increase in breast conservation in 16 years of clinical trials conducted by the Austrian Breast & Colorectal Cancer Study Group Ann Surg 2003; 237: 556-564 141 IF: 6,664 Schueller G, Kettenbach J, Sedivy R, Stift A, Friedl J, Gnant M, Lammer J Heat shock protein expression induced by percutaneous radiofrequency ablation of hepatocellular carcinoma in vivo Int J Oncol 2004; 24:609-13 142 IF: 3,056 Stift A, Friedl J, Gnant M, Herbst F, Jakesz R, Wenzl E Gastrointestinal Autonomic Nerve Tumors: A surgical point of view World J Gastroenterology 2004; 10: 2447-2451 143 IF: 3,318 Schoppmann S, Bayer G, Aumayr K, Taucher S, Geleff S, Rudas M, Kubista E, Hausmaninger H, Samonigg H, Gnant M, Jakesz R, Horvat R, and the Austrian Breast and colorectal Cancer Study Group Prognostic value of lymphangiogenesis and lymphovascular invasion in invasive breast cancer Annals Surg 2004; 204: 306-312 IF: 5,907 2 Univ. Prof. Dr. Michael Gnant 144 Originalarbeiten - 17 - Stift A, Sachet M, Yagubian R, Bittermann C, Dubsky P, Pfragner R, Niederle B, Jakesz R, Gnant M, Friedl J Dendritic cell vaccination in medullary thyroid carcinoma Clin Cancer Res 2004; 10:2944-2953 145 IF: 5,623 Taucher S, Rudas M, Mader R, Gnant M, Dubsky P, Roka S, Bachleitner-Hofmann T, Kandioler D, Steger G, Mittlboeck M, Jakesz R Prognostic markers in breast cancer: the reliability of HER2/neu status in core needle biopsy of 325 primary breast cancer patients Wien Klin Wochenschr 2004; 116:26-31 146 IF: 0,901 Wenzel C, Hussian D, Bartsch R, Pluschnig U, Locker GJ, Rudas M, Gnant M, Jakesz R, Zielinski C, Steger G Preoperative therapy with epidoxorubicin and docetaxel plus trastuzumab in patients with primary breast cancer: a pilot study J Cancer Res Clin Oncol 2004; 130: 400-404 147 IF: 2,409 Schueller G, Kettenbach J, Sedivy R, Bergmeister H, Stift A, Friedl J, Gnant M, Lammer J Expression of heat shock proteins in human hepatocellular carcinoma after radiofrequency ablation in an animal model Oncology Rep 2004; 12: 495-499 148 IF: 1,356 Roka S, Rudas M, Taucher S, Dubsky P, Bachleitner-Hofmann T, Kandioler D, Gnant M, Jakesz R High nuclear grade and negative estrogen receptor are significant risk factors for recurrence in DCIS Eur J Surg Oncol 2004; 30; 243-247 149 IF: 1,882 Schippinger W, Jagoditsch M, Sorre C, Gnant M, Steger G, Hausmaninger H, Mlineritsch B, Schaberl-Moser R, Mischinger HJ, Hofbauer F, Holzberger P, Mittlböck M, Jakesz R, for the ABCSG A prospective randomized trial to study the role of levamisole and interferon alfa in an adjuvant theapy with 5-FU for stage-III colon cancer Br J Cancer 2005; 92: 1655-62 150 IF: 4,115 Early Breast Cancer Trialists Collaborative Group (EBCTCG) Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: an overview of the randomised trials Lancet 2005; 365: 1687-1717 151 IF: 23,878 Pokorny H, Gnant M, Rasoul-Rockenschaub S, Gollackner B, Steiner B, Steger G, Steininger R, Muehlbacher F Does additional doxorubicin chemotherapy improve outcome in patients with hepatocellular carcinoma treated by liver transplantation? Am J Transplant 2005; 5: 788-94 152 IF: 6,002 Wenzel C, Bartsch R, Locker GH, Hussian D, Pluschnig D, Sevelda U, Gnant M, Jakesz R, Zielinski C, Steger GG Preoperative chemotherapy with epidoxorubicin, docetaxel, and capecitabine plus pegfilgrastim in patients with primary breast cancer Anticancer Drugs 2005; 16: 441-5 IF: 2,052 2 Univ. Prof. Dr. Michael Gnant 153 Originalarbeiten - 18 - Pfragner R, Skofitsch G, Hoger H, Jech M, Rinner B, Siegl V, Niederle B, Gnant M, Friedl J, Stift A Medullary thyroid carcinoma: autologous tumor cell lins for dendritic cell vaccination Anticancer Res 2005; 25:4225-30 154 IF: 1,604 Gornikiewicz A, Zommer A, Jakesz R, Gnant M, Brostjan C Retroviral targeting of proliferating endothelial cells Acta Biochim Pol 2005; 52: 731-5 155 IF: 1,863 Jakesz R, Jonat W, Gnant M, Mittlboeck M, Greil R, Tausch C, Hilfrich J, Kwasny W, Menzel C, Samonigg H, Seifert M, Gademann G, Kaufmann M, for the ABCSG and the GABG Switching of postmenopausal women with endocrine-responsive early breast cancer to anastrozole after 2 years' adjuvant tamoxifen: combined results of ABCSG trial 8 and ARNO 95 trial Lancet 2005; 366: 455-62 156 IF: 23,887 Dubsky P, Friedl J, Stift A, Bachleitner-Hofmann T, Jakesz R, Gnant M, Weigel G Inosine 5'-monophosphate dehydrogenase inhibition by mycophenolic acid impairs maturation and function of dendritic cells Clin Chim Acta 2006; 364: 139-47 157 IF: 2,328 Gnant M Bisphosphonates and the prevention of osteoporosis in the adjuvant setting Breast Cancer Online 2005; Nov; 1-3, e55 158 IF: 0,000 Piccart-Gebhart M, Procter M, Leyland-Jones B, Goldhirsch A, Untch M, Smith I, Gianni L, Baselga J, Bell R, Jackisch C, Cameron D, Dowsett M, Barrios C, Steger G, Huang C, Andersson M, Inbar M, Lichinitser M, Lang I, Nitz U, Iwata H, Thomssen C, Lohrisch C, Suter T, chemotherapy Rüschoff J, Sütö T, V, Ward breast C, Straehle C, McFadden E, Dolci M, Gelber R, Trastuzumab after adjuvant inGreatorex HER2-positive cancer N Eng J Med 2005; 353: 1659-72 159 IF: 44,016 Steger G, Bartsch R, Wenzel C, Pluschnig U, Hussian D, Sevelda U, Locker G, Gnant M, Jakesz R, Zielinski C Fulvestrant ('Faslodex') in pre-treated patients with advanced breast cancer: a single-center experience Eur J Cancer 2005; 41: 2655-61 160 IF: 3,706 Clarke M, Collins R, Darby S, Davies C, Elphinstone P, Evans E, Godwin J, Gray R, Hicks C, James S, MacKinnon E, McGale P, McHugh T, Peto R, Taylor C, Wang Y and the Early Breast Cancer Trialists Collaborative Group (EBCTCG) Effects of radiotherapy and of differences in the extend of surgery for early breast cancer on local recurrence and on 15-year survival: an overview of the randomised trials Lancet 2005; 366: 2087-106 161 IF: 23,878 Wenzel C, Locker G, Bartsch R, Pluschnig U, Hussian D, Zielinski CC, Rudas M, Gnant M, Jakesz R, Steger GG Preoperative second-line chemotherapy induces objective responses in primary breast cancer Wien Klin Wochenschr 2005; 117: 48-52 IF: 0,901 2 Univ. Prof. Dr. Michael Gnant 162 Originalarbeiten - 19 - Fitzal F, Sporn E, Draxler W, Mittlboeck M, Taucher S, Rudas M, Roedl O, Helbich T, Jakesz R, Gnant M Preoperative core needle biopsy does not increase local recurrence rate in breast cancer patients Breast Cancer Res Treatm 2006; 97: 9-15 163 IF: 4,671 Ausch C, Maddoff RD, Gnant M, Rosen HR, Garcia-Aguilar J, Hoelbling N, Herbst F, Buxhofer V, Holzer B, Rothenberger DA, Schiessel R Aetiology and surgical management of toxic megacolon Int J Colorectal Disease 2006; 8: 195-201 164 IF: 2,006 Gnant M Surgical Oncology - a proud speciality European Surgery 2006; 38/1: 2-3 165 IF: 0,000 Dubsky P, Gnant M The endocrine origin and different characters of breast cancers - recent research on hormone receptors and endocrine treatment Breast Care 2006; 1: 124-8 166 IF: 0,242 Schoppmann S, Fenzl A, Nagy K, Unger S, Bayer G, Geleff S, Gnant M, Horvath R, Jakesz R, Birner P VEGF-C expressing tumor-associated macrophages in lymph node positive breast cancer: impact on lymphangiogenesis and survival Surgery 2006; 139: 839-46 167 IF: 2,977 Gnant M Management of bone loss induced by aromatase inhibitors Cancer Invest 2006; 24: 328-30 168 IF: 2,335 Schoppmann SF, Fenzl A, Schindl M, Bachleitner-Hofmann T, Nagy K, Gnant M, Horvat R, Jakesz R, Birner P Hypoxia inducible factor-1alpha correlates with VEGF-C expression and lymphangiogenesis in breast cancer Breast Cancer Res Treat 2006; 99: 135-41 169 IF: 4,671 Fitzal F, Gnant M Breast conservation: evolution of surgical strategies Breast 2006; 12S2: 165-73 170 IF: 1,705 Gnant M Breast Centers Revisited - a critical perspective Breast Care 2006; 1: 150-1 IF: 0,242 2 Univ. Prof. Dr. Michael Gnant 171 Originalarbeiten - 20 - Schueller G, Schima W, Schueller-Weidekamm C, Weber M, Stift A, Gnant M, Prokesch R Multidetector CT of Pancreas_ Effects of Contrast Material Flow Rate and Individualized Scan Delay on Enhancement of Pancreas and Tumor Contrast Radiology 2006; 241: 441-8 172 IF: 5,251 Gnant M, Jonat W, Boccardo F, Kaufmann M, Rubagotti A, Zuna I, Greenwood M, Jakesz R Effectiveness of switching from adjuvant tamoxifen to anastrozole in postmenopausal women with hormone-sensitive early-stage breast cancer: a meta-analysis Lancet Oncology 2006; 7: 991-996 173 IF: 10,119 Bachleitner-Hofmann T, Strohschneider M, Krieger P, Sachet M, Dubsky P, Hayden H, Schoppmann S, Pfragner R, Gnant M, Friedl J, Stift A Heat shock treatment of tumor lysat-pusled DCs enhances their capacity to elicit antitumor T-cell responses against medullary thyroid carcinoma J Clin Endocrinol Metab 2006; 91: 4571-7 174 IF: 5,799 Gnant M, Blaha P Breast Cancer Chemoprevention - not yet there Breast Care 2006; 1: 295-6 175 IF: 0,242 Bachleitner-Hofmann T, Schoppmann S, Rudas M, Birner P, Wiener H, Dubsky P, Blaha P, Sporn E, Panhofer P, Fitzal F, Roka S, Kandioler D, Gnant M, Jakesz R A case of phylloides tumor with focal transition into low-grade lymphangiosarcoma Breast Care 2006; 1: 391-4 176 IF: 0,242 Wenzel C, Bartsch R, Hussian D, Pluschnig U, Altoraj G, Zielinski CC, Lang A, Hais A, Jakesz R, Gnant M, Steger G Invasive ductal carcinoma and invasive lobular carcinoma of breast differ in response following neoadjuvant therapy with epidoxorubicin and docetaxel + G-CSF Br Canc Res Treat 2007; 104: 109-14 177 IF: 4,453 Fitzal F, Riedl O, Wutzl L, Draxler W, Rudas M, Pluschnig U, Handl-Zeller L, Dubsky P, Bachleitner-Hofmann T, Steger G, Jakesz R, Gnant M Breast conserving surgery for T3/T4 breast cancer: an analysis of 196 patients Breast Cancer Res Treatm 2007; 103: 45-52 178 IF: 4,453 Beslija S, Bonneterre J, Bustein H, Cocquyt V, Gnant M, Goodwin P, Heinemann V, Jassem J, Köstler WJ, Krainer M, Menard S, Miles D, Petit T, Petruzelka L, Possinger K, Schmid P, Stadtmauer E, Stockler M, Van Belle S, Vogel C, Wilcken N, Wiltschke C, Zielinski on C, Zwierzina Second Consensus MedicalHTreatment of Metastatic Breast Cancer Ann Oncol 2007; 18:215-25 179 IF: 4,875 Gnant M, Mlineritsch B, Luschin-Ebengreuth G, Grampp S, Kaessmann H, Schmid M, Menzel C, Piswanger-Soelkner JC, Galid A, Mittlboeck M, Hausmaninger H, Jakesz R, and the ABCSG Zoledronic Acid effectively prevents Cancer treatment-induced bone loss in premnopausal women receiving adjuvant andocrine therapy for hormone responsive breast cancer J Clin Oncol 2007; 25: 820-8 IF: 15,484 2 Univ. Prof. Dr. Michael Gnant 180 Originalarbeiten Steger GG, Galid A, Gnant M, Mlineritsch B, Lang A, Tausch C, Rudas M, Greil R, Wenzel C, Singer C, Haid A, Poestlberger S, Samonigg H, Luschin-Ebengreuth G, Kwasny W, Klug E, Kubista E, Menzel C, Jakesz R, and the ABCSG Pathologic complete response with 6 vs. 3 cycles oof Neoadjuvant epirubicin/decetaxel + G-CSF in operable breast cancer: resutls of ABCSG-14 J Clin Oncol 2007; 25: 2012-8 181 IF: 15,678 Fitzal F, Krois W, Trischler H, Wutzel L, Riedl O, Kühbelböck U, Wintersteiner B, Cardoso MJ, Dubsky P, Gnant M, Jakesz R, Wild T The use of a breast symmetry index for objective evaluation of breast cosmesis Breast 2007;4:429-35 182 - 21 - IF: 1,739 Schindl M, Gnant M, Schoppmann S, Horvat R, Birner P Overexpression of the human homologue for Caenorhabditis elegans cul-4 gene is associated with poor outcome in node-negative breast cancer Anticancer Res 2007; 27: 949-52 183 IF: 1,414 Lipton A, Gnant M, Aapro M Managing aromatase inhibitor-associated bone loss in breast cancer Womans Health 2007; 3:441-448 184 IF: 0,000 Jakesz R, Greil R, Gnant M, Schmid M, Kwasny W, Kubista E, Mlineritsch B, Tausch C, Stierer M, Hofbauer F, Renner K, Dadak C, Ruecklinger E, Samonigg H, on behalf of the ABCSG Extended adjuvant therapy with Anastrozole among postmenopausal breast cancer patients: Results from the randomized Austrian Breast and Colorectal Cancer Study Group Trial 6a J Natl Canc Inst 2007; 99:1845-53 185 IF: 15,678 LHRH-agonists in Early Breast Cancer Overview Group Use of luteinising-hormone-releasing hormone agonists as adjuvant treatment in premenopausal patients with hormone-receptor-positive breast cancer: a meta-analysis of individual patient data from randomised adjuvant trials Lancet 2007; 369: 1711-23 IF: 28,638 186 Suter T, Procter M, van Veldhuisen D, Muscholl M, Bergh J, Carlomagno C, Perren T, Passalacqua R, Bighin C, Klijn J, Ageev F, Hitre E, Groetz J, Iwata H, Knap M, Gnant M, Muehlbauer S, Spence A, Gelber R, Piccart-Gebhart M Trastuzumab-associated cardiac adverse effects in the Herceptin Adjuvant trial J Clin Oncol 2007; 25:3859-65 187 IF: 15,484 Poetter R, Gnant M, Kwasny W, Tausch C, Handl-Zeller L, Pakisch B, Taucher S, Hammer J, Luschin-Ebengreuth G, Schmid M, Sedlmayer F, Stierer M, Reiner G, Kapp K, Hofbauer F, Rottenfusser A, Poestlberger S, Haider K, Draxler W, Jakesz R; on behaslf the ABCSGor anastrozole with or without whole breast irradiation in women with Lumpectomy plusoftamoxifen favourable early breast cancer Int J Radiat Oncol 2007; 68: 334-40 188 IF: 4,290 Fitzal F, Nehrer G, Deutinger M, Jakesz R, Gnant M Novel strategies in oncoplastic surgery for breast cancer: immediate partial reconstruction of breast defects Eur Surg 2007; 39:330-39 IF: 0,000 2 Univ. Prof. Dr. Michael Gnant 189 Originalarbeiten - 22 - Bartsch G, Wenzel C, Altoraj F, Pluschnig U, Rudas M, Mader R, Gnant M, Zielinski C, Steger G Capecitabine and Trastuzumab in heavily preatreated patients with metastatic breast Cancer J Clin Oncol 2007; 25: 3853-8 190 IF: 15,484 Fitzal F, Nehrer G, Hoch D, Riedl O, Gutharc S, Deutinger M, Jakesz R, Gnant M An oncoplastic procedure for central and medio-cranial breast cancer Eur J Surg Oncol 2007; 33: 1158-63 191 IF: 3,917 Bartsch T, Wenzel C, Altrofaj G, Pluschnig U, Mader R, Gnant M, Jakesz R, Rudas M, Zielinski C, Steger G HER-2 and progesterone receptor are not predictive of response to fulvestrant treatment Clin Cancer Res 2007; 13: 4435-9 192 IF: 6,250 Smith I, Procter M, Gelber R, Guillaume S, Teyereislova A, Dowsett M, Goldhirsch A, Untch M, Mariani G, Baselga J, Kaufmann M, Cameron D, Bell R, Bergh J, Coleman R, Wardlay A, Harbeck N, Lopez R, Mallmann P, Gelmon K, Wilcken N, Wist E, Rovira P, of Piccart-Gebhart M,after for theadjuvant HERA study team 2-year follow-up trastuzumab chemotherapy in HER2-positive breast cancer: a randomised controlled trial Lancet 2007; 369: 29-36 193 IF: 28,638 Schippinger W, Samonigg H, Schaberl-Moser R, Greil R, Thodtmann R, Tschmelitsch J, Jagoditsch M, Steger G, Jakesz R, Herbst F, Hofbauer F, Rabl H, Wohlmuth P, Gnant M, Thaler J, for the ABCSG A prospective randomized phase III trial of adjuvant chemotherapy with 5-fuorouracil and leucovorin in patients with stage II colon cancer Br J Cancer 2007; 97(8):1021-7 194 IF: 4,635 Dubsky P, Hayder H, Sachet M, Bachleitner-Hofmann T, Hassler M, Pfragner R, Gnant M, Stift A, Friedl J Allogenic tumor lysate can serve as both antigen source and protein supplementation for dendritic cell culture Cancer Immunol Immunother 2008;57(6):859-70 195 IF: 3,728 Taucher S, Steger G, Jakesz R, Tausch C, Wette V, Schippinger W, Kwasny W, Reiner G, Greil R, Bartsch R, Dubsky P, Poestlberger S, Tschmelitsch J, Samonigg H, Gnant M The potential risk of neoadjuvant chemotherapy in breast cancer patients - results from a prospective randomised trial of the Austrian Breast and Colorectal Cancer Study Group (ABCSG-07) Breast Cancer Res Treatm 2008; 112: 309-16 196 IF: 4,453 Aapro M, Abrahamsson P, Body J, Coleman R, Colomer R, Costa L, Crino L, Dirix L, Gnant M, Gralow J, Hadji P, Hortobagyi G, Jonat W, Lipton A, Monnier A, Paterson A, Rizzoli R, Saad F, Thuerlimann B Guidance on the use of bisphosphonates in solid tumours: recommendations of an international expert panel Annals of Oncology 2008; 19: 420-32 197 IF: 4,875 Bartsch R, Welzel C, Gampenrieder S, Pluschnig U, Altoraj G, Rudas M, Mader R, Dubsky P, Rottenfusser A, Gnant M, Zielinski C, Steger G Trastuzumab and gemcitabine as salvage therapy in heavily pre-treated patients with metastatic breast cancer Cancer Chemother Pharmacol 2008; 62: 903-10 IF: 2,568 2 Univ. Prof. Dr. Michael Gnant 198 Originalarbeiten - 23 - Stadler G, Wieser M, Streubel B, Stift A, Friedl J, Gnant M, Niederle B, Katinger H, Pfragner R, Grillari J, Voglauer R Low telomerase activity: possible role in the progression of human medullary thyroid carcinoma Eur J Cancer 2008; 44: 866-75 199 IF: 4,454 Rudas M, Lehnert M, Huynh A, Jakesz R, Singer C, Lax S, Schippinger W, Dietze O, Greil R, Stiglbauer W, Kwasny W, Grill R, Stierer M, Gnant M, Filipits M, for the ABCSG Cyclin D1 expression in breast cancer and tamoxifen therapy Clin Cancer Res 2008; 14: 1767-74 200 IF: 6,250 Li J, Haensch W, Rudas M, Kemmer W, Warnick P, Fischer J, Gnant M, Schlag PM, Bembenek A The localization of small tumor deposits in the SLN predicts Non-SLN macrometastases in breast cancer patients Eur J Surg Oncol 2008; 34: 857-862 201 IF: 3,917 Early Breast Cancer Trialists’ Collaborative Group (EBCTCG) Adjuvant chemotherapy in oestrogen-receptor-poor early breast cancer: patient-level meta-analysis of randomised trials Lancet 2008; 371: 29-40 IF: 28,638 202 Mlineritsch B, Tausch C, Singer C, Luschin-Ebengreuth G, Jakesz R, Ploner F, Stierer M, Melbinger E, Menzel C, Urbania A, Fridrik M, Steger G, Wohlmuth P, Gnant M, Greil R, on behalf of the ABCSG Exemestane as primary systemic treatment for hormone receptor positive postmenopausal breast cancer patients: a phase II trial opf the Austrian Breast and Colorectal Cancer Study Group (ABCSG -17) Breast Cancer Res Treat 2008; 112: 203-213 IF: 4,453 203 Dubsky P, Sevelda P, Jakesz R, Hausmaninger H, Samonigg H, Seifert M, Desnison U, Mlineritsch B, Steger G, Kwansy W, Stoeger H, Bartsch R, Stierer M, Taucher S, Fridrik M, Schippinger W, Greil R, Poetter R, Gnant M Anemia is a significant prognostic factor in local relapse-free survival of premenopausal primary breast cancer patients receiving adjuvant CMF chemotherapy Clin Cancer Res 2008; 14: 2082-7. 204 IF: 6,250 Sahora K, Trenkwitz D, Akan B, Kuehrer I, Goetzinger P, Gnant M Moderne Tumortherapie des Pankreaskarzinoms J Gastroenterol Hepatol Erkr 2008; 6: 17-24 205 IF: 0,000 Pestalozzi BC, Francis P, Quinaux E, Dolci S, Azambuja E, Gelber RD, Viale G, Balil A, Andersson M, Nordenskjöld B, Gnant M, Gutierrez J, Lang I, Crown JPA, Piccart-Gebhart M, on behalf of the BIG 02-98 Collaborative Group Is risk of central nervous system (CNS)-relaps related to adjuvant taxane treatment in node-positive breast cancer? Results of the CNS-substudy in the Intergroup phase III BIG 02-98 trial Ann Oncol 2008; 19: 1837-41 206 IF: 5,179 Sahora K, Akan B, Kuehrer I, Goetzinger P, Gnant M Neoadjuvante Therapie des Pankreaskarzinoms Wien Klin Wochenschr 2008; 3: 6-9 IF: 0,885 2 Univ. Prof. Dr. Michael Gnant 207 Originalarbeiten - 24 - Dubsky P, Gnant M (Neo-)Adjuvant Chemotherapy in Breast Cancer - Trials, errors and new Rationales from the SABCS 2007 memo 2008; 1: 23-36 208 IF: 0,000 Gnant M, Mlineritsch B, Luschin-Ebengreuth G, Kainberger F, Kaessmann H, Piswanger-Soelkner C, Seifert M, Schippinger W, Menzel C, Dubsky P, Fitzal F, Steger G, Greil R, Marth C, Kubista E, Samonigg H, Jakesz R, on behalf of the ABCSGendocrine therapy plus zoledronic acid in premenopausal women with early-stage breast Adjuvant cancer: 5-year follow-up of the ABCSG-12 bone-mineral density substudy Lancet Oncology 2008; 9:840-9. 209 IF: 12,274 Fitzal F, Mittlboeck M, Trischler H, Krois W, Nehrer G, Deutinger M, Jakesz R, Gnant M Breast-conserving therapy for centrally located breast cancer Ann Surg 2008; 247: 470-6 210 IF: 7,446 Gnant M, Dubsky P, Fitzal F, Steger G, Jakesz R Adjuvant endocrine Therapy in premenopausal women with breast cancer Breast Care 2008; 3: 311-6 211 IF: 0,242 Ludwig H, Auberger T, Burghuber O, Gnant M, Hopfinger G, Jaeger U, Keil F, Kornek G, Linkesch W, Petrau E, Pirker R, Pittermann E, Reinthaller A, Samonigg H, Steger G, Stockenhuber F, Studnicky M, Weiss G, Zielinski C Einsatz von Erythropoease-stimulierenden Proteinen bei anämischen Patienten mit malignen Erkrankungen Wien Klin Wochenschr 2008; 120: 507-13 212 IF: 1,000 Gnant M, Mlineritsch B, Schippinger W, Luschin-Ebengreuth G, Poestlberger S, Menzel C, Jakesz R, Kubista E, Marth C, Greil R, on Behalf of the ABCSG Adjuvant endocrine therapy plus zoledronic acid in premenopausal breast cancer New Engl J Med 2009; 360:679-91 213 IF: 52,589 Riedl O, Fitzal F, Mader N, Dubsky P, Rudas M, Mittlboeck M, Gnant M, Jakesz R Intraoperative frozen section analysis for breast conservingt therapy in 1.016 patients with breast cancer Eur J Surg Oncol 2009; 35: 264-70 214 IF: 3,917 Gnant M To measure the unmeasurable World J Surgery 2009; 33: 52-3 215 IF: 2,696 Singer C, Hudelist G, Fuchs E, Koestler W, Fink-Retter A, Gschwantler-Kaulich D, Gnant M, Rudas M, Czerwenka K, Kubista E Incomplete surgical resection of DCIS results in activation of HER-2 in residual breast cancer cells Endocrine Rel Cancer 2009; 16: 73-83 IF: 5,193 2 Univ. Prof. Dr. Michael Gnant 216 Originalarbeiten - 25 - Gnant M The evolving role of Zoledronic Acid in early breast cancer OncoTargets and Therapy 2009; 2: 95-104 217 IF: Bachleitner-Hofmann T, Friedl J, Hassler M, Hayden H, Dubsky P, Sachet M, Rieder E, Pfragner R, Brostjan C, Riss S, Niederle B, Gnant M, Stift A Pilot trial of autologous dendritic cells loaded with tumor lysate(s) from allogeneic tumor cell lines in patients with metastatic medullary thyroid carcinoma Oncol Rep. 2009; 21:1585-92 218 IF: 1,588 Sahora K, Kührer I, Trenkwitz D, Friedl J, Sautner T, Goetzinger P, Gnant M Pankreaskarzinom und periampulläres Karzinom J Gastroenterol Hepatol Erkr 2009; 7: 36-46 219 IF: 0,669 Hayden H, Fridl J, Dettke M, Sachet M, Hassler M, Dubsky P, Bachleitner-Hofmann T, Gnant M, Stift A Cryopreservation of monocytes is superior to cryopreservation of immature or semi-mature dendritic cells for dendritic cell based immunotherapy J Immunoth 2009; 32: 658-64 220 IF: 3,203 Blaha P, Dubsky P, Fitzal F, Bachleitner-Hofmann T, Steger G, Jakesz R, Gnant M Breast cancer chemoprevention - a vision not yet realised Eur J Cancer Care 2009; 18; 438-46 221 IF: 1,038 Gnant M, Dubsky P, Fitzal F, Bachleitner-Hofmann T, Exner R, Blaha P, Jakesz R, Schippinger W, Greil R Bisphosphonates as adjuvant treatment for breast cancer Curr Breast Canc Rep 2009; 1: 54-63 222 IF: Bartsch R, Mlineritsch B, Gnant M, Niernberger T, Pluschnig U, Greil R, Wenzel C, Sevelda P, Thaler J, Rudas M, Pober M, Zielinski CC, Steger GG; on behalf of the Austrian Fulvestrant Registry. The Austrian fulvestrant registry: results from a prospective observation of fulvestrant in postmenopausal patients with metastatic breast cancer Breast Cancer Res Treat 2009; 115: 373-80 223 IF: 4,453 Blaha P, Exner R, Dal Borgo A, Bigenzahn S, Panhofer P, Riedl O, Schoppmann S, Bachleitner-Hofmann T, Sporn E, Pluschnig U, Fitzal F, Steger G, Jakesz R, Dubsky P, Gnant M Is endocrine Therapy really pleasant? Considerations about the long-term use of antihormonal therapy and its benefit/side effect ratio Breast Care 2009; 4:155-61 224 IF: 0,500 Coleman R, Gnant M New results from the use of bisphosphonates in cancer patients. Curr Opin Support Palliat Care 2009; 3: 213-8 IF: 2,073 2 Univ. Prof. Dr. Michael Gnant 225 Originalarbeiten - 26 - Goldhirsch A, Ingle JN, Gelber RD, Coates AS, Thürlimann B, Senn HJ; Panel members. Thresholds for therapies: highlights of the St Gallen International Expert Consensus on the primary therapy of early breast cancer 2009. Ann Oncol 2009; 20:1319-29 226 IF: 5,647 Beslija S, Bonneterre J, Burstein HJ, Cocquyt V, Gnant M, Heinemann V, Jassem J, Köstler WJ, Krainer M, Menard S, Petit T, Petruzelka L, Possinger K, Schmid P, Stadtmauer E, Stockler M, Van Belle S, Vogel C, Wilcken N, Wiltschke C, Zielinski CC, Zwierzina H; for the Central European Cooperative Oncology Group Third Consensus on Medical Treatment of Metastatic Breast Cancer Ann Oncol 2009; 20: 1771-85 227 IF: 5,647 Gnant M, Dubsky P, Fitzal F, Blaha P, Schoppmann SF, Steger G, Marth C, Samonigg H, Huettner K, Fohler H, Ruecklinger E, Jakesz R, Greil R, on behalf of the Austrian Breast and Colorectal Cancer Study Group (ABCSG) Maintaining Bone Density in patients undergoing treatment for breast cancer: is there an adjuvant benefit? Clin Breast Cancer 2009; 9: s18-27 228 IF: 2,065 Filipits M, Rudas M, Heinzl H, Jakesz R, Kubista E, Lax S, Schippinger W, Dietze O, Greil R, Stiglbauer W, Kwasny W, Nader A, Stierer M, Gnant M Low p27 expression predicts early relapse and death in postmenopausal hormone receptor-positive breast cancer patients receiving adjuvant tamoxifen therapy Clin Cancer Res 2009; 15: 5888-94 229 IF: 6,747 Gnant M Bisphosphonates in the prevention of disease recurrence: Current results and ongoing trials Curr Cancer Drug Targets 2009; 9: 824-33 230 IF: 5,385 Akan B, Sahora K, Puhalla H, Gnant M, Jakesz R, Goetzinger P Cystic neoplasms of the pancreas: Conservative or operative treatment? Eur Surg 2009; 40:220-6 231 IF: 0,629 Gnant M, Blaha P, Dubsky P, Exner R, Fitzal F, Sporn E, Panhofer P, DalBorgo A, Bigenzahn S, Jakesz R, Steger G Adjuvant bisphosphonates in endocrine-responsive breast cancer: what is their place in therapy? Ther Adv Med Oncol 2009; 1: 123-36 232 IF: Gnant M Adjuvant endocrine therapy in premenopausal women with breast cancer BCO 2009; 12 (5): 1-8 (e8) 233 IF: 0,000 Bartsch R, DeVries C, Pluschnig U, Dubsky P, Horvath Z, Gampenrieder S, Rudas M, Mader R, Rottenfusser A, Wiltschke C, Gnant M, Zielinski CC, Steger GG Predicting for activity of second-line trastuzumab-based therapy in HER2-positive advanced breast cancer Br J Cancer 2009; 9: 367 IF: 4,346 2 Univ. Prof. Dr. Michael Gnant 234 Originalarbeiten - 27 - Gnant M, Steger GG Fighting overtreatment in adjuvant breast cancer therapy Lancet 2009; 374: 2029-30 235 IF: 30,758 Gnant M Bisphosphonates in the adjuvant treatment of early breast cancer Breast Cancer Res 2009; 11: S17 236 IF: 4,696 Dowsett M, Cuzick J, Ingle J, Coates A, Forbes J, Bliss J, Buyse M, Baum M, Buzdar A, Colleaoni M, Coombes C, Snowdon C, Gnant M, Jakesz R, Kaufmann M, Boccardo F, Godwin J, Davies C, Peto R, for the Aromatase Inhibitor Overview Group of breast cancer outcomes in adjuvant trials of aromatase inhibitors versus tamoxifen Meta-analysis J Clin Oncol 2010; 28: 509-18 237 IF: 18,970 Kaufmann M, von Mickwitz G, Morrow M, The Biedenkopf Expert Panel Members Local-Regional Treatment of Primary Breast Cancer: Consensus Recommendation from an International Expert Panel Cancer 2010; 116: 1184-9 238 IF: 5,131 Gnant M, Eidtmann H The anti-tumor effect of bisphosphonates: ABCSG-12, ZO-FAST and more... Crit Rev Onc Hem 2010; 74: S2-6 239 IF: 4,589 Lux MP, Nowitzki C, Wallwiener D, Kreienberg R, Jonat W, Gnant M, Beckmann M Mammakarzinom: Bisphosphonate in der Adjuvanz - auch aus gesundheitsökonomischer Sicht eine sinnvolle Therapie Geburtsh Frauenheilk 2010; 70: 8-11 240 IF: 0,342 Delea T, Taneja C, Sofrygin O, Kaura S, Gnant M Cost-Effectiveness of Zoledronic Acid Plus Endocrine Therapy in Premenopausal Women with Hormone-Responsive Early Breast Cancer Clin Breast Cancer 2010; 4: 267-74 241 IF: 2,790 Gnant M The evolution of bone-targeted therapies: Introduction Sem Oncol 2010; 37: S1 242 IF: 3,355 Lux MP, Reichelt C, Wallwiener D, Kreienberg R, Jonat W, Gnant M, Beckmann M Results of the Zometa® Cost-utility model for the German healthcare system based omn the results of the ABCSG-12 study Onkologie 2010; 33: 360-8 IF: 1,153 2 Univ. Prof. Dr. Michael Gnant 243 Originalarbeiten - 28 - Gnant M Neue Studiendaten zur endokrinen Langzeittherapie Gyn Spectrum 2010; 1: 4-6 244 IF: 0,000 Starlinger P, Moll H, Assinger A, Nemeth C, Gruenberger B, Gruenberger T, Kuehrer I, Schoppmann S, Gnant M, Brostjan C Thrombospondin-1: a unique marker to identify in vitro platelet activation when monitoring in vitro processes J Thromb Hemosta 2010; 8: 1809-19 245 IF: 4,701 Gnant M Can oral bisphophonates really reduce the risk of breast cancer in healthy women? J Clin Oncol 2010; 28: 3548-51 246 IF: 18,970 Gampenrieder S, Bartsch R, Scheuer R, Pluschnig U, Dubsky P, Gnant M, Zielinski C, Steger G Capecitabine and vinorelbine as an all-oral chemotherapy in HER2-negative locally advanced and metastatic breast cancer Breast Care 2010; 5: 158-162 247 IF: 0,364 Gnant M Neoadjuvant Treatment and Breast Conserving Surgery - a success of clinical research in breast cancer Wien Med Wochenschr 2010; 160: 163-6 248 IF: 0,000 Early Breast Cancer Trialists' Collaborative Group (EBCTCG), Correa C, McGale P, Taylor C, Wang Y, Clarke M, Davies C, Peto R, Bijker N, Solin L, Darby S Overview of the ransomized trials of radiotherapy in ductal carcinoma in situ of the breast J Natl Cancer Inst Monogr 2010; 41: 162-77 249 IF: 14,697 Gnant M, Dubsky PC Closing in on the unknown enemy Lancet Oncol 2010; 11:402-3 250 IF: 17,764 Bartsch R, Steger G, Gnant M, Ziebermayr R Breast Cancer: Rank Ligand Inhibition Breast Care 2010; 5: 320-325 251 IF: 0,364 Schoppmann S,Tamandl D, Roberts L, Jomrich G, Schoppmann A, Zwrtek R, Dubsky P, Gnant M, Jakesz R, Birner P HER-2/neu-expression correlates with vascular endothelial growth factor-C and lymphangiogenesis in llymph node positive breast cancer Ann Oncol 2010; 21: 955-60 IF: 6,452 2 Univ. Prof. Dr. Michael Gnant 252 Originalarbeiten - 29 - Neville-Webbe H, Gnant M, Coleman R Potential anticancer properties of bisphosphonates Semin Oncol 2010; 7: S53-65 253 IF: 3,355 Mouridsen H, Lonning P, Beckmann M, Blackwell K, Doughty J, Gligorov J, Llombart-Cussac A, Robidoux A, Thürlimann B, Gnant M Use of aromatase inhibitors and bisphosphonates as an anti-cancer therapy in postmenopausal breast cancer Expert Rev Anticancer Ther 2010; 11: 1825-36 254 IF: 2,976 Gnant M, Hadji P Prevention of bone metastases and management of bone health in early breast cancer Breast Cancer Research 2010; 12: 216 255 IF: 4,859 Michlmayr A, Bachleitner-Hofmann T, Baumann S, Marchetti-DeschmannM , Rech-Weichselbraun I, Burghuber C, Pluschnig U, Bartsch R, Graf A, Greil R, Allmaier G, Steger G, Gnant M, Bergmann M, Oehler R Modulation of plasma complement by the initial dose of epirubicin / docetaxwl therapy in breast cancer and its predictive value Br J Cancer 2010; 103: 1201-8 256 IF: 4,831 Gnant M 10 years of ATAC: one question answered, many others unresolved Lancet Oncology 2010; 11: 1109-10 257 IF: 17,764 Gnant M Adjuvant Bisphosphonate therapy in postmenopausal breast cancer patients Breast Care 2010; 5: 298-304 258 IF: 0,364 Hadji P, Gnant M, Aapro M, Lipton A, Coleman R Dosing of Zoledronic Acid throughout the treatment continuum in breast cancer Crit Rev Oncol Hematol 2011; 79:175-88 259 IF: 4,411 Tausch C, Steger G, Haid A, Jakesz R, Fridrik M, Reitsamer R, Poestlberger S, Lang A, Gnant M, Greil R, on behalf of the ABCSG Sentinel Node Biopsy after primary chemotherapy in breast cancer: A note of caution from results from ABCSG-14 Breast J 2011; 17: 230-8 260 IF: 1,643 Gnant M Adjuvant Zoledronic Acid reduces disease recurrence in breast cancer: Antitumor effects on the seed and the soil Curr Cancer Ther Rev 2011; 7: 111-18 IF: 2 Univ. Prof. Dr. Michael Gnant 261 Originalarbeiten - 30 - Starlinger P, Brugger P, Schauer D, Sommerfeldt S, Tamandl D, Kuehrer I, Schoppmann S, Gnant M, Brostjan C Myelosuppression of thrombocytes and monocytes is associated with a lack of synergy between chemotherapy and anti-VEGF treatment Neoplasia 2011; 13; 5: 419-27 IF: 5,946 262 Kerjaschki D, Bago-Horvath Z, Rudas M, Sexl V, Wolbank S, Schneckenleithner C, Wolbank S, Bartel G, Krieger S, Kalt R, Hantusch B, Keller T, Nagy-Bojarski K, Huttary N, Raab I, Lackner K, Krautgasser K, Schachner H, Kaserer K, Rezar S, Madlener S, Vonach C, Davidovits A, Nosaka H, Haemmerle M, Viola K, Dolznig H, Schreiber M, Nader lymph A, Mikulits W, Lipoxigenase mediates Invasion of intrametastatic lymphatic vessels and propagates node metastasis of human mammary carcinoma xenografts in mouse IF: 13,069 J Clin Invest 2011; 132: 2000-12 263 Sahora K, Kuehrer I, Fitzal F, Schindl M, Koelblinger C, Goetzinger P, Gnant M NeoGemTax - Gemcitabine and docetaxel as neoadjuvant treatment for locally advanced nonmetatasized pancreatic cancer World J Surg 2011; 35: 1580-9 264 IF: 2,362 Gnant M Intravenous bisphosphonates for breast cancer: Impact on patient outcomes and scientific concepts Breast Disease 2011; 33: 71-81 265 IF: Starlinger P, Alidzanovic L, Schauer D, Brugger P, Sommerfeldt S, Kuehrer I, Schoppmann S, Gnant M, Brostjan C Platelet-stored angiogenesis factors: Clinical monitoring is prone to artifacts Disease Markers 2011; 31: 55-65 266 IF: 1,642 Gnant M, Mlineritsch B, Stoeger H, Luschin-Ebengruth G, Heck D, Menzel C, Jakesz R, Seifert M, Hubalek M, Pristauz G, Bauernhofer T, Eidtmann H, Eiermann W., Steger G, Kwasny W, Dubsky P, Hochreiner G,, Forsthuber EP, Fesl C, Greil R, on behalf ofendocrine the ABCSG therapy plus zoledronic acid in premenopausal women with early breast cancer: Adjuvant 62-month follow-up from ABCSG-12 Lancet Oncol 2011; 12: 631-41 267 IF: 22,589 Filipits M, Rudas M, Jakesz R, Dubsky P, Fitzal F, Singer C, Dietze O, Greil R, Jelen A, Sevelda P, Freibauer C, Müller V, Jänicke F, Schmidt M, Kölbl H, Rody A, kaufmann M, Schroth W, Brauch H, Schwab M, Fritz P, Weber KE, Feder IS, Henning G, Gehrmann M, GnantofM distant recurrence in estrogen recpetor-positive HER2-negative breast A new molecular predictor cancer adds independent information to conventional clinical risk factors Clin Cancer Res 2011; 17: 6012-20 268 IF: 7,742 Gnant M Zoledronic Acid in Breast Cancer: Latest Findings and Interpretations Ther Adv Med Oncol 2011; 3: 293-301 269 IF: Goldhirsch A, Wood WC, Coates AS, Gelber RD, Thuerlimann B, Senn HJ, & Panel members Strategies for subtypes—dealing with the diversity of breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2011 Ann Oncol 2011; 22: 1736-47 IF: 6,425 2 Univ. Prof. Dr. Michael Gnant 270 Originalarbeiten - 31 - Gnant M, Harbeck N, Thomssen C St. Gallen 2011: Summary of the consensus discussion Breast Care 2011; 6: 136-41 271 IF: 0,446 Fitzal F, Riedl O, Mittlboeck M, Dubsky P, Bartsch R, Steger G, Jakesz R, Gnant M Oncologic safety of breast conserving surgery after tumor downsizing by neoadjuvant therapy: A retrospective single centre cohort study Breast Cancer Res Treatm 2011; 127: 121-128 272 IF: 4,431 Öfner D, DeVries A, Schaberl-Mosef R, Greil R, Rabl H, Tschmelitsch J, Zitt M, Kapp K, Fastner G, Keil F, Eisterer W, Jäger R, Offner F, Gnant M, Thaler J, for the TAKO 05/!BCSG R02 Trial Investigators Preoperative oxaliplatin, capecitabine and external beam readiotherapy in patients with newly diagnosed, primary operable, cT3NxM0 low rectal cancer - a Phase II study Strahlenther Oncol 2011; 187: 100-7 273 IF: 3,561 Early Breast Cancer Trialists' Collaborative Group (EBCTCG) Relevance of breast hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials Lancet 2011; 378: 771-84 274 IF: 38,278 Gnant M, Piccart-Gebhart M, Goldhirsch A, Baselga J, Cameron D, Di Leo A, Dowsett M, Gelber M, von Mickwitz G, Wadvogel C, Straehle C Developing an international network for breast cancer research: the Breast International Group (BIG) experience Clin Invest 2011; 1(5): 623-28 275 IF: 13,069 Starlinger P, Brugger P, Reiter C, Schauer D, Sommerfeldt S, Tamandl D, Kuehrer I, Schoppmann S, Gnant M, Brostjan C Discrimination between circulating endothelial cells and blood cell populations with overlapping phenotype reveals distinct regulation and predictive potential in cancer therapy Neoplasia 2011; 13: 980-90 276 IF: 5,946 Pfeiler G, Koenigsberg R, Fesl C, Mlineritsch B, Stoeger H, Singer C, Poestlberger S, Steger G, Seifert M, Dubsky P, Taucher S, Samonigg H, Bjelic-Radisic V, Greil R, Marth C, Gnant M Impact of Body Mass Index on the efficacy of endocrine therapy in premenopausal patients with breast cancer: An analysis of the prospective ABCSG-12 trial J Clin Oncol 2011; 29: 2653-9 277 IF: 18,372 Hadji P, Aapro M, Body J, Bundred N, Brufsky A, Coleman R, Gnant M, Guise T, Lipton A Management of aromatase inhibitor-associated bone loss in postmenopausal women with breast cancer: Practical guidance for prevention and treatment Annals of Oncology 2011; 22: 2546-55 278 IF: 6,425 Gnant M Targeted therapies: Adjuvant bisphosphonates - an option with low estrogen? Nature Reviews Clinical Oncology 2011; 8: 698-9 IF: 11,963 2 Univ. Prof. Dr. Michael Gnant 279 Originalarbeiten Pagani O, Partridge A, Korde L, Badve S, Bartlett J, Albain K, Gelber R, Goldhirsch A; Breast International Group; North American Breast Cancer Group Endocrine Working Group Pregnancy after breast cancer: if you wish, ma'am Breast Cancer Res Treatm 2011; 129: 309-17 280 IF: 4,431 Sahora K, Kuehrer I, Eisenhut A, Akan B, Koellblinger C, Goetzinger P, Teleky B, Jakesz R, Pecl-Radosavlejvid M, Ba'ssalamah A, Zielinski C, Gnant M NeoGemOx - Gemcitabine and oxaliplatin as neoadjuvant treatment for locally advanced nonmetastasized pancreatic cancer Surgery 2011; 143: 311-20 281 - 32 - IF: 3,103 Early Breast Cancer Trialists' Collaborative Group (EBCTCG) Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer mortality in women with early breast cancer: analysis of individual patient data on 10,801 women2011; in 17378: randomised Lancet 1707-16 trials IF: 38,278 282 Bago-Horvath Z, Rudas M, Dubsky P, Singer C, Dietze O, Greil R, Jelen A, Boehm G, Jasarevic Z, Lang A, Gruber C, Poestlberger S, Filipits M, Gnant M, on behalf of the ABCSG Adjuvant sequencing of tamoxifen and anastrozole is superior to tamoxifen alone in postmenopausal women with low proliferating breast cancer Clin Cancer Res 2011;17: 7828-34 283 IF: 7,742 Gnant M Bisphosphonates in the adjuvant treatment of breast cancer - Rationale and clinical data Clin Invest 2011; 1: 97-107 284 IF: 13,069 Bartsch R, Berghoff A, Pluschnig U, Bago-Horvath Z, Dubsky P, Rottenfusser A, DeVries C, Rudas M, Fitzal F, Dieckmann K, Mader R, Gnant M, Zielinski C, Steger G Impact of anti-HER2 therapy on overall survival in HER2-positive metastatic breast cancer patients with brain metastases Br J Cancer 2012; 106: 25-31 285 IF: 5,082 Gnant M, Steger GG Dual HER2 inhibition in breast cancer treatment Lancet 2012; 379; 596-8 286 IF: 39,060 Knauer M, Gnant M, Fitzal F, Panel Members Results of the first Austrian multidisciplinary expert panel on controversies in local treatment of breast cancer Breast Care 2012; 7: 61-66 287 IF: 0,680 Tausch C, Taucher S, Dubsky P, Seifert M, Reitsamer R, Kwasny W, Jakesz R, Fitzal F, Filipcic L, Fridrik M, Greil R, Gnant M Prognostic Value of Number of Removed Lymph Nodes, Number of Involved Lymph Nodes, and Lymph Node Ratio in 7502 Breast Cancer Patients Enrolled onto Trials of the Austrian Breast and Colorectal Cancer Study Group (ABCSG) Ann Surg Oncol 2012; 19: 1808-17 IF: 4,166 2 Univ. Prof. Dr. Michael Gnant 288 Originalarbeiten - 33 - Gnant M Zoledronic Acid in the treatment of early stage breast cancer: Is there a final verdict? Curr Oncol Reports 2012; 14:35–43 289 IF: 3,327 Kaufmann M, von Minckwitz G, Mamounas EP, Cameron D, Carey LA, Cristofanilli M, Denkert C, Eiermann W, Gnant M, Harris JR, Karn T, Liedtke C, Mauri D, Rouzier R, Ruckhaeberle E, Semiglazov V, Symmans WF, Tutt A, Pusztai L Recommendations from an International Consensus Conference on the Current Status and Future of Neoadjuvant Systemic Therapy in Primary Breast Cancer Ann Surg Oncol 2012; 19: 1508-16 290 IF: 4,166 Hadji P, Aapro M, Costa L, Gnant M Antiresorptive treatment options and bone health in cancer patients - safety profile and clinical considerations Cancer Treatm Rev 2012; 38, 815-24 291 IF: 6,054 Baselga J, Campone M, Piccart M, Burris HA, Rugo, HS, Sahmoud T, Noguchi S, Gnant M, Pritchard KI, Lebrun F, Beck JT, Ito Y, Yardley D, Deleu I, Perez A, Bachelot T, Vittori L, Xu C, Mukhopadhyay P, Lebwohl D, Hortobagyi GN Everolimus in postmenopausal hormone-receptor-positive advanced breast cancer N Eng J Med 2012; 366: 520-9 292 IF: 53,298 Exner R, Krois W, Mittlböck M, Dubsky P, Jakesz R, Gnant M, Fitzal F Objetively measured breast symmetry has no influence on quality of life in breast cancer patients Eur J Surg Oncol 2012; 38: 130-6 293 IF: 2,614 Resch G, DeVries A, Oefner D, Eisterer W, Rabl H, Jagoditsch M, Gnant M, Thaler J, on behalb of the ABCSG Preoperative treatment with capecitabine, bevacizumab and radiotherapy for primary locally advanced rectal cancer - A two stage phase II clinical trial Radiother Oncol 2012; 102: 10-3 294 IF: 5,580 Hadji P, Gnant M, Body JJ, Bundred NJ, Brufsky A, Coleman RE, Guise T, Lipton A, Aapro MS Cancer treatment-induced bone loss in premenopausal women: A need for therapeutic intervention? Cancer Treatm Rev 2012; 38: 798-806 295 IF: 6,054 Early Breast Cancer Trialists' Collaborative Group (EBCTCG) Comparisons between different polychemotherapy regimens for early breast cancer: meta-analyses of long-term outcome among 100 000 women in 123 randomised trials Lancet 2012; 379: 432-44 296 IF: 39,060 Gnant M, Dubsky P, Hadji P Bisphosphonates: prevention of bone metastases in breast cancer Recent Results Cancer Res. 2012;192:65-91 IF: 2,000 2 Univ. Prof. Dr. Michael Gnant 297 Originalarbeiten Barrios C, Forbes JF, Jonat W, Conte P, Gradishar W, Guzudar A, Gelmon K, Gnant M, Bonneterre J, Toi M, Hudis C, Robertson J The sequential use of endocrine treatment for advanced breast cancer: where are we? Ann Oncol 2012; 23: 1378-86 298 - 34 - IF: 7,384 Fitzal F, Mittlboeck M, Steger G, Bartsch G, Rudas M, Dubsky P, Riedl O, Jakesz R, Gnant M Neoadjuvant chemotherapy increases the rate of breast conservation on lobular-type breast cancer patients Ann Surg Oncol 2012; 19: 519-26 IF: 4,166 299 Dubsky P, Jakesz R, Mlineritsch B, Poestlberger, Graz2, Kwasny W, Tausch C, Samonigg H, Haider K, Fitzal F, Singer C, Stierer M, Sevelda P, Luschin-Ebengreuth G, Taucher S, Rudas M, Bartsch R, Steger G, Greil R, Filipcic L, Gnant M, on behalf of the and ABCSG Taxoxifen Anastrozole as a sequencing strategy: A randomized controlled trial in postmenopausal patients with endocrine-responsive early breast cancer: Final results from the Breast Cancer Study Group JAustrian Clin Oncol 2012;and 30: Colorectal 722-8 IF: 18,372 300 Gnant M Anticancer activity of bisphosphonates in breast cancer Anticancer Agents Med Chem 2012; 12: 114-22 301 IF: 3,144 Berghoff A, Bago-Horvath Z, De Vries C, Dubsky P, Pluschnig U, Rudas M, Rottenfusser A, Knauer M, Eiter H, Fitzal F, Dieckmann K, Mader RM, Gnant M, Zielinski CC, Steger GG, Preusser M, Bartsch R. Brain metastases free survival differs between breast cancer subtypes Br J Cancer 2012; 106: 440-6 302 IF: 5,082 Schoppmann SF, Berghoff A, Dinhof C, Jakesz R, Gnant M, Fitzal F, Dubsky P, Jesch B, Birner P Podoplanin-expressing cancer-associated fibroblasts are associated with poor prognosis in invasive breast cancer Breast Cancer Res Treatm 2012; 134: 237-44 303 IF: 4,469 Gnant M, Balic M, Petru E, Raunik W, Singer CF, Steger GG, Watzke IM, Brodowicz T Treatment of bone metastases in patients with advanced breast cancer Breast Care 2012; 7: 92-8 304 IF: 0,680 Coleman RE, Gnant M, Morgan G, Clezardin P Bone Targeted Agents: Effects on disease progression and mortality in solid tumour and haematological cancers J Nat Cancer Inst 2012; 104: 1059-1067 305 IF: 14,700 Gnant M Overcoming endocrine resistance in breast cancer: importance of mammalian target of rapamycin (mTOR) inhibition Expert Rev of Anticancer Ther 2012; 12: 1579-89 IF: 2,652 2 Univ. Prof. Dr. Michael Gnant 306 Originalarbeiten Bartsch R, Bago-Horvath Z, Berghoff A, DeVries C, Pluschnig U, Dubsky P, Rudas M, Mader RM, Rottenfusser A, Fitzal F, Gnant M, Zielinski CC, Steger GG Ovarian function suppression and fulvestrant as endocrine therapy in premenopausal women with metastatic breast cancer Eur J Cancer 2012; 48: 1932-8 307 - 35 - IF: 5,061 Hadji P, Coleman R, Gnant M, Green J The impact of menopause on bone and implications for breast cancer growth and metastasis Ann Oncol 2012; 23: 2782-90 308 IF: 7,384 Gnant M, Clezardin P Direct and indirect Anticancer Activity of Bisphosphonates: A review of published literature Cancer Treatm Rev 2012; 38: 407-15 309 IF: 6,054 Hubalek M, Gnant M, Bartsch R, Kapp K, Lang A, Lax S, Lukas P, Neunteufel W, Reitsamer R, Sandbichler P, Schrenk P, Tamussino K, Pristauz G, Tschmelitsch J, Singer C, Zeimet A, Marth C Axilladissektion bei positivem Sentinel-Lymphknoten - Ergebnisse Innsbrucker Konsuskonferenz Geburtsh Frauenheilk 2012; 72:299–304 310 IF: 0,848 Gnant M, Beermann B 8th European Breast Cancer Conference (EBCC-8) Breast Care 2012; 7: 170-6 311 IF: 0,680 Gnant M Adjuvant bisphosphonates: a new standard of care? Curr Opin Oncol 2012, 24:635-42 312 IF: 4,101 Thomssen C, Gnant M, Harbeck N Entwicklungen der forschenden Pharmaindustrie Breast Care 2012; 7: 155-64 313 IF: 0,680 Arnold T, Micklmayr A, Baumann S, Burghuber C, Pluschnig U, Bartsch R, Steger G, Gnant M, Bergmann M, BachleitnerHofmann T, Oehler R Plasma HMGB-1 after the initial dose of epirubicin/docetaxel in cancer. Eur J Clin Invest 2013; 43:286-91 314 IF: 3,365 Gnant M The Role of Mammalian Target of Rapamycin (mTOR) Inhibition in the Treatment of Advanced Breast Cancer Curr Oncol Rep 2013; 15: 14-23 IF: 2,545 2 Univ. Prof. Dr. Michael Gnant 315 Originalarbeiten Dubsky P, Filipits M, Jakesz R, Rudas M, Singer C, Greil R, Dietze O, Luisser I, Klug E, Sedivy R, Bachner M, Mayr D, Schmidt M, Gehrmann M, Petry C, Weber KE, Kronenwett R, Brase JC, Gnant M EndoPredict improves the prognostic classification derived from common clinical guidelines in ERpositive, HER2-negative early breast cancer Ann Oncol 2013; 24:640-7 316 - 36 - IF: 7,384 Campone M, Lebrun F, Beck JT, Gnant M, Neven P, Pritchard KI, Bachelot T, Provencher L, Rugo HS, Piccart M, Hortobagyi GN, Nunzi M, Heng D, Baselga J, Komorowski A, Noguchi S, Horiguchi J, Bennett L, Ziemiecki R, Zhang J, Cahana A, Taran T, Sahmoud T, Burris HA Health-related quality of life and disease symptoms in postmenopausal women with advanced breast cancer treated with everolimus plus exemestane versus exemestane monotherapy Curr Med Res Opinion 2013; 24: 2206-23 IF: 2,380 317 Gnant M, Pfeiler G, Stoeger H, Mlineritsch B, Fitzal F, Balic M, Kwasny W, Seifert M, Stierer M, Dubsky P, Greil R, Steger G, Samonigg H, Fesl C, Jakesz R, on behalf of the ABCSG The predictive impact of body mass index on the efficacy of extended adjuvant endocrine treatment with anastrozole in postmenopausal patients with breast cancer - an analysis of the randomized ABCSG 6a trial Brit J Cancer 2013; 109: 589-96 IF: 5,061 318 Dubsky P, Brase JC, Jakesz R, Rudas M, Singer CF, Greil T, Dietze O, Luisser I, Klug E, Sedivy R, Bachner R, Mayr D, Schmidt M, Gehrmann MC, Petry C, Weber KE, Fisch K, Kronenwett R, Gnant M, Filipits M, on behalf of the ABCSG The EndoPredict score provides prognostic information on late distant metastases in ER+/HER2breast cancer patients Br J Cancer 2013; 109: 2959-64 319 IF: 5,082 Thaler J, Ay C, Mackman N, Metz-Schimmerl S, Stift J, Kaider A, Müllauer L, Gnant M, Scheithauer W, Pabinger I Microparticle-associated tissue factor activity in patients with pancreatic cancer: Correlation with clinicopathological features Eur J Clin Invest 2013; 43: 277-85 320 IF: 3,365 Harbeck N, Thomssen C, Gnant M St. Gallen 2013: Brief preliminary summary of the Consensus discussion Breast Care 2013; 8: 102-9 IF: 0,911 321 Burris HA, Lebrun F, Hugo HS, Beck JT, Piccart M, Neven P, Baselga J, Petrakova K, Hortobagyi G, Komorowski A, Chouinard E, Young R, Gnant M, Pritchard KI, Bennett L, Rixxi JF, Bauly H, Taran T, Sahmoud T, Noguchi S Health-related Quality of Life of Advanced Breeast Cancer Patierns treated with Everolimus plus Exemestane versus Placebo plus Exemestane in the Phase 3, randomized, controlled, BOLERO-2 trial Cancer 2013; 119: 1908-15 IF: 3,662 322 Gnant M, Greil R, Hubalek M, Steger G Everolimus in postmenopausal, hormone receptor-positive advanced breast cancer - Summary and results of an Austrian Expert Panel discussion Breast Care 2013; 8: 293-9 323 IF: 0,911 Pfeiler G, Stoeger H, Dubsky P, Mlineritsch B, Singer C, Balic M, Fitzal F, Moik M, Kwasny W, Selim U, Renner K, Ploner F, Steger GG, Seifert M, Hofbauer F, Sandbichler P, Samonigg H, Jakesz R, Greil R, Fesl C, M, on behalf of the ABCSG Efficacy of Gnant tamoxifen ± aminoglutethimide in normal weight and overweight postmenopausal patients with hormone-receptor positive breast cancer – an analysis of 1509 patients of the ABCSG-06 trial Br J Cancer 2013; 108: 1408-14 IF: 5,082 2 Univ. Prof. Dr. Michael Gnant 324 Originalarbeiten Goetz M, Suman V, Ames M, Gnant M, Filipits M, Hoskin T, Safgren S, Kuffel M, Jakesz R, Rudas M, Greil R, Dietze O, Lang A, Offner F, Reynolds C, Weinshilboum R, Ingle J CYP2D6 metabolism and patient outcome in the Austrian Breast and Colorectal Study Group trial (ABCSG) 8 Clin Cancer Res 2013; 19: 500-7 325 IF: 7,837 Campone M, Bachelot T, Gnant M, Deleu I, Rugo HS, Pistilli B, Noguchi S, Shtivelband M, Pritchard KI, Provencher L, Burris HA, Hart LL, Melichar B, Hoartobagyi GN, Arena F, Baselga J, Panneerselvam A, Héniquez A, El-Hashimi M, Taran T, Sahmoud T, Piccart M Effect of visceral metastases on the efficacy and safety of Everolimus in postmenopausal woem with advanced breast cancer: subgroup analysis from the BOLERO-2 study Eur J Cancer 2013; 49: 2621-32 326 IF: 5,061 Yardley DA, Noguchi S, Prichard KI, Burris HA, Baselga J, Gnant M, Hortobagyi GN, Capone M, Pistilli B, Piccart M, Melichar B, Petrakova K, Arena FP, Erdkamp F, Harb WA, Fend W, Cahana A, Taran T, Sahmoud T, Lebwohl D, Rugo HS Everolimus plus exemestane in postmenopausal patients with HR(+) breast cancer: BOLERO-2 final progression-free survival analysis. Adv Ther 2013; 30:870-84 327 IF: 2,125 Zagouri F, Sergentanis TN, Koutoulidis V, Sparber C, Steger GG, Dubsky P, Zografos GC, Psaltopoulou T, Gnant M, Dimopoulos MA, Bartsch R Aromatase inhibitors with or without a gonadotropin-releasing hormone analogue in male breast cancer patients: a case series Br J Cancer 2013; 108: 2259-63 328 - 37 - IF: 5,082 Goldhirsch A, Winer EP, Coates AS, Gelber RD, Piccart-Gebhart M, Thürlimann B, Senn HJ, and Panel Members Personalizing the treatment of women with early breast cancer: highlights of the St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2013 Ann Oncol 2013; 24: 2206-23 329 IF: 7,384 Hadji P, Coleman R, Gnant M Bone effects of mammalian target of rapamycin (mTOR) inhibition with everolimus Crit Rev Oncol Hematol 2013; 101-11 330 IF: 5,270 Valachis A, Polyzos NP, Coleman RE, Gnant M, Eidtmann H, Brufsky AM, Aft R, Tevaarwerk AJ, Swenson K, Lind P, Mauri D Adjuvant Therapy With Zoledronic Acid in Patients With Breast Cancer: A Systematic Review and Meta-Analysis Oncologist 2013; 18 (4): 353-61 331 IF: 4,095 Berghoff AS, Bago-Horvath Z, Dubsky P, Rudas M, Pluschnig U, Wiltschke C, Gnant M, Steger GG, Zielinski CC, Bartsch R Impact of Her-2-Targeted Therapy on Overall Survival in Patients With Her-2 Positive Metastatic Breast Cancer Breast J 2013; 19:149-55 332 IF: 1,831 Gnant M Guidelines: Usefulness and Limitations Breast Care 2013; 8: 172-173 IF: 0,911 2 Univ. Prof. Dr. Michael Gnant 333 Originalarbeiten Gnant M, Baselga J, Rugo HS, Noguchi S, Burris HA, Piccart M, Hortobagyi GN, Eakle J, Mukai H, Iwata H, Geberth M, Hart LL, Hadji P, El-Hashimy M, Rao S, Taran T, Sahmoud T, Lebwohl D, Campone M, Pritchard KI Everolimus reduced bone marker levels and progressive disease in bone in BOLERO-2 J Nat Cancer Inst 2013; 105: 654-63 334 IF: 14,336 Pritchard KI, Burris HA, Ito Y, Rugo HS, Dakhil S, Hortobagyi GN, Campone M, Csőszi T, Baselga J, Puttawibul P, Piccart M, Heng D, Noguchi S, Srimuninnimit V, Bourgeois H, Gonzalez Martin A, Osborne K, Panneerselvam A, Taran T, Sahmoud T, Gnant M of Everolimus With Exemestane Versus Exemestane Alone in Elderly Patients Safety and Efficacy With HER2-Negative, Hormone-Receptor-Positive Breast Cancer in BOLERO-2 Clin Breast Cancer 2013, 13: 421-32 335 IF: 2,422 Pfeiler G, Königsberg R, Hadji P, Fitzal F, Maroske M, Dressel-Ban G, Zellinger J, Exner R, Seifert M, Singer C, Gnant M, Dubsky P Impact of Body Mass Index (BMI) on estradiol depletion by aromatase inhibitors in postmenopausal women with early breast cancer Br J Cancer 2013; 109: 1522-7 336 - 38 - IF: 5,082 Thomssen C, Diel I, Gnant M, Goldmann-Posch U, Göschke C, Haidinger R, Janni W, Lin NU Follow-up after breast cancer diagnosis Breast Care 2013; 8: 457-60 337 IF: 0,911 AGO; DGS; SGS; ÖGS; Panelists; Executive Board Members, Hoffmann J, Souchon R, Lebeau A, Öhlschlegel C, Gruber G, Rageth C, Weber W, Harbeck N, Janni W, Kreipe H, Fitzal F, Resch A, Bago-Horvath Z, Peintinger F German, Austrian and Swiss consensus conference on the diagnosis and local treatment of the axilla in breast cancer. Eur J Cancer 2013; 49: 2277-83 338 IF: 4,819 Gnant M Role of Bisphosphonates in postmenopausal women with breast cancer Cancer Treatm Rev 2014; 40: 476-84 339 IF: 6,024 Panhofer P, Ferenc V, Schütz M, Gleiss A, Dubsky P, Jakesz R, Gnant M, Fitzal F Standardization of morbidity assessment in breast cancer surgery using the Clavien Dindo Classification Int J Surg 2014; 12: 334-9 IF: 1,436 340 Gnant M, Filipits M, Greil R, Stoeger H, Rudas M, Bago-Horvath Z, Mlineritsch B, Kwasny W, Singer C, Jakesz R, Dubsky P, Fitzal F, Bartsch R, Steger G, Balic M, Ressler S, Cowens W, Storhoff J, Ferree S, Schaper C, Liu S, Fesl C, Nielsen T, on behalf of the ABCSG Predicting distant recurrence in receptor-positive breast cancer patients with limited clinicopathological risk: using the PAM50 score in 1,478 postmenopausal patients of the ABCSG-08 trial treated with25: adjuvant Ann Oncol 2014; 339-45 endocrine therapy alone IF: 7,384 341 Harmuth S, Wewalka M, Holst JJ, Nemecek R, Thalhammer S, Schmid R, Sahora K, Gnant M, Miholic J Distal gastrectomy in pancreaticoduodenectomy is associated with accelerated gastric emptying, enhanced postprandial release of GLP-1, and improved insulin sensitivity J Gastrointest Surg 2014; 18: 52-9 IF: 2,361 2 Univ. Prof. Dr. Michael Gnant 342 Originalarbeiten - 39 - Gnant M, Bartsch R, Steger GG HER2-positive breast cancer: a new piece of the puzzle Lancet Oncol 2014; 15: 668-9 343 IF: 24,229 Rugo HS, Pritchard KI, Gnant M, Noguchi S, Piccart M, Hortobagyi G, Baselga J, Perez A, Geberth M, Csoszi T, Chouinard E, Srimuninnimit V, Puttawibul P, Eakle J, Feng W, Bauly H, El-Hshimi M, Taran T, Sahmoud T, Burris HA Incidence and time course of everolimus-related adverse events in postmenopausal women with hormone-receptor-positive advanced breast cancer: insights from BOLERO-2 Ann Oncol 2014; 25: 808-15 IF: 7,384 344 Neven P, Markopoulos C, Tanner M, Marty M, Kreienberg R, Atkins L, Franquet A, Gnant M, Neciosup S, Tesarova P, Barni S, Deschamp V The impact of educational materials on compliance and persistence rates with adjuvant aromatase inhibitor treatment: first year results from the Compliance of ARomatase Inhibitors AssessmenT In Daily practice Breast 2014; 23:through 393-9 Educational approach (CARIATIDE) Study IF: 3,929 345 Filipits M, Nielsen T, Rudas M, Greil, R, Stöger H. Jakesz R, Bago-Horvath Z, Dietze O, Regitnig P, Gruber-Rossipal C, Müller-Holzner E, Singer CF, Mlineritsch B, Dubsky P, Bauernhofer T, Hubalek M, Knauer M, Trapl H, Fesl C, Schaper C, Ferree S, Liu S,risk-of-recurrence Cowens JW, Gnant M(ROR) score predicts risk for late distant recurrence after endocrine The PAM50 therapy in postmenopausal women with endocrine-responsive early breast cancer: A study on 1,246 patients from the ABCSG-8 trial Clin Cancer Res 2014; 20: 1298-305 IF: 7,837 346 Bartsch R, Frings S, Marty M, Awada A, Berghoff AS, Conte P, Dickin S, Enzmann H, Gnant M, Hasmann M, Hendriks HR, Llombart A, Massacesi C, vonMinckwitz G, Penult-Llorca F, Scaltriti M, Wein W, Yarden Y, Zwierzina H, Zielinski CC, for the Biotherapy Association Present and Development Future Breast Cancer(BDA) Management - Bench to Bedside and Back: A Positioning Paper of Academia, Regulatory Authorities and Pharmaceutical Industry Ann Oncol 2014; 25: 773-80 347 IF: 7,384 Sahora K, Schindl M, Kuehrer I, Werba G, Fitzal F, Goetzinger P, Gnant M Gemcitabine-based neoadjuvant chemotherapy for locally advanced pancreatic cancer does not affect mortality and morbidity after pancreatic resection European Surgery 2013; in press DOI 10.1007/s10353-013-0213-0 348 Bartsch R, Berghoff AS, Rudas M, Dubsky P, DeVries C, Sattlberger C, Mader MR, Sparber C, Fitzal F, Gnant M, Rottenfusser A, Zielinski CC, Preusser M, Steger GG Taxanes plus Trastuzumab compared to oral Vinorelbine plus Trastuzumab in HER2-overexpressing metastatic breast cancer patients Cancer Chemotherapy and Pharmacology 2014 [in press] 349 IF: 2,795 Foedermayr M, Sebesta M, Rudas M, Berghoff A, Promberger R, Preusser M, Dubsky P, Fitzal F, Gnant M, Steger G, Welermann A, Zielinski C, Zach O, Bartsch R BRCA-1 methylation and TP53 mutation in triple-negative breast cancer patients without pathological complete response to taxan-based neoadjuvant chemotherapy Cancer Chemother Pharmacol 2014; 73: 771-8 350 IF: 0,148 IF: 2,571 Steger GG, Greil R, Lang A, Rudas M, Fitzal F, Mlineritsch B, Hartmann BL, Bartsch R, Melbinger E, Hubalek M, Stoeger H, Dubsky P, Ressler S, Petzer AL, Singer CF, Muss C, Jakesz R, Gampenrieder SP, Zielinski CC, Fesl C, Gnant M; on behalf of the and Austrian Breast and Colorectal Studycapecitabine Group (ABCSGas neoadjuvant treatment for early breast Epirubicin docetaxel with or without cancer: final results of a randomized phase III study (ABCSG-24). Ann Oncol 2014; 25:366-71 IF: 7,384 2 Univ. Prof. Dr. Michael Gnant 351 Originalarbeiten - 40 - Tamandl D, Sahora K, Prucker J, Schmid R, Holst JJ, Miholic J, Goetzinger P, Gnant M Impact of the reconstruction method on delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy: A prospective randomized study World J Surg 2014; [published ahead of print Oct 12, 2013] 351 Exner R, Bago-Horvath Z, Bartsch R, Mittlboeck M, Retèl V, Fitzal F, Rudas M, Singer C, Pfeiler G, Gnant M, Jakesz R, Dubsky P The multigene signature MammaPrint® impacts on multidisciplinary team decisions in ER-positive, HER2-negative early breast cancer Brit J Cancer 2014; 111: 837-42 352 IF: 2,348 IF: 4,817 Early Breast Cancer Trialists' Collaborative Group (EBCTCG) Effect of radiotherapy after mastectomy and axillary surgery on 10-year recurrence and 20-year breast cancer mortality: meta-analysis of individual patient data for 8135 women in 22 randomised trials. Lancet 2014; 383: 2127-35 IF: 39,207 353 Gnant M Modern therapeutic concepts of early breast cancer Breast Care (Basel) 2014; 92: 85-6 354 IF: 0,911 Pfeiler G, Königsberg R, Fesl C, Greil R, Stoeger H, Singer C, Knauer M, Steger G, Seifert M, Dubsky P, Fitzal F, Balic M, Bjelic-Radisic V, Mlineritsch B, Marth, C, Gnant M, on behalf of the ABCSG Change of Body Mass Index (BMI) during adjuvant endocrine therapy and its impact on treatment efficacy in premnopausal patients with breast cancer: an analysis of the ABCSG-12 trial Brit J Cancer 2014 [in press] 356 IF: 4,817 Heitzer E, Mach M, Filipits M, Resel M, Graf R, Weiszenbacher B, Lax S, Gnant M, Wrba F, Greil R, Dietze O, Hofbauer F, Boehm G, Hoefler G, Samonigg H, Schaberl-Moser R, Balic M, Dandachi N Promoter methylation status of PCDH10, SPARC, and UCHL1 predict survival in stage II colorectal cancer patients treated with or without 5-fluorouracil-based chemotherapy Modern Pathology 2014; 27: 906-15 357 IF: 7,837 Sahora K, Schindl M, Kuehrer I, Eisenhut A, Werba G, Brostjan C, Teleky B, Ba'ssalamah A, Stift J, Schoppmann SF, Gnant M A phase II trial of two durations of bevacizumab added to neoadjuvant gemcitabine for borderline and locally advanced pancreatic cancer Anticancer Res 2014; 34: 2377-84 358 IF: 1,872 Gangl O, Sahora K, Kornprat P, Margreiter C, Primavesi F, Bareck E, Schindl M, Laengle F, Oefner D, Mischinger HJ, Pratschke J, Gnant M, Fuegger R Preparing for prospective clinical trials - a national initiative of an excellence registry for consecutive pancreatic cancer resections World J Surg 2014; 38: 456-62 359 IF: 3,373 Fitzal F, Filipits M, Rudas M, Greil R, Dietze O, Samonigg H, Lax S, Herz W, Dubsky P, Bartsch R, Kronenwett R, Gnant M The genomic expression test Endopredict® is a prognostic tool for identifying risk of local recurrence in postmenopausal endocrine receptor-positive, her2neu-negative breast cancer patients randomized within the prospective ABCSG 8 trial Brit J Cancer 2015 [in press] IF: 4,817 2 Univ. Prof. Dr. Michael Gnant 360 Originalarbeiten Foedermayr M, Sebesta M, Rudas M, Berghoff AS, Promberger R, Preusser M, Dubsky P, Gnant M, Steger GG, Weltermann A, Zielinski CC, Zach O, Bartsch R Association of TP53 mutations with TP53 codon 72 polymorphism and outcome in triple-negative breast cancer patients. J Hum Genetics 2015 [submitted] 361 IF: Piccart M, Hortobagyi GN, Campone M, Pritchard KI, Lebrun F, Ito Y, Noguchi S, Perez A, Rugo HS, Deleu I, Burris HA 3rd, Provencher L, Neven P, Gnant M, Shtivelband M, Wu C, Fan J, Feng W, Taran T, Baselga J. Everolimus plus exemestane for hormone-receptor-positive, human epidermal growth factor receptor -2-negative advanced breast cancer: overall survival results from BOLERO-2. Ann Oncol. 2014; 25: 2357-62 362 IF: Berghoff A, Bartsch R, Preusser M, Ricken G, Steger GG, Bago-Horvath Z, Rudas M, Streubel B, Dubsky P, Gnant M, Fitzal F, Zielinski CC, Birner P Co-overexpression of HER2/HER3 is a predictor of imparied survival in breast cancer patients Breast 2014; 23: 637-43 363 IF: 2,581 Blank PR, Filipits M, Dubsky P, Gutzwiller F, Lux MP, Brase JC, Weber KE, Rudas M, Greil R, Loibl S, Szucs TD, Kronenwett R, Schwenkglenks M, Gnant M Cost-Effectiveness of prognostic gene expression signature-based stratification of early breast cancer patients Pharmacoeconomics 2015: 33: 179-90 364 IF: Zardavas D, Maetens M, Irrthum A, Goulioti T, Engelen K, Fumagalli D, Salgado R, Aftimos P, Saini KS, Sotiriou C, Campbell P, Dinh P, von Minckwitz G, Gelber RD, Dowsett M, Di Leo A, Cameron D, Baselga J, Gnant M, Goldhirsch A, Norton L, Piccart M. The AURORA initiative for metastatic breast cancer. Br J Cancer. 2014; 111: 1881-7 365 - 41 - IF: Sestak I, Cuzick J, Dowsett M, Lopez-Knowles E, Filipits M, Dubsky P, Cowens JW, Ferree S, Schaper C, Fesl C, Gnant M Prediction of Late Distant Recurrence After 5 Years of Endocrine Treatment: A Combined Analysis of Patients From the Austrian Breast and Colorectal Cancer Study Group 8 and Arimidex, Tamoxifen or in Combination Randomized Trials Using the PAM50 Risk of Recurrence IF: Score JAlone Clin Oncol 2014; Oct 20 online 18,370 366 Early Breast Cancer Trialists’ Collaborative Group (EBCTCG)* Patient-level meta-analysis of randomised trials of aromatase inhibitors versus tamoxifen in 31,920 postmenopausal women with ER-positive early breast cancer Lancet 2015 [submitted] 367 IF: Bergen E, .............. Gnant M,...., Bartsch R Taxanes plus Trastuzumab compared to oral Vinorelbine plus Trastuzumab ind HER2-overexpressing metastatic breast cancer Breast Care 2015; [in press] 368 IF: 0,911 Coleman R, Powles T, Gnant M, bnm Effects of adjuvant bisphosphonate treatment on early breast cancer disease outcomes: A meta-analysis of individual patient data from randomised trials Lancet 2015 [accepted] IF: 20,000 2 Univ. Prof. Dr. Michael Gnant 369 Originalarbeiten - 42 - Sonnenblick A, Azim HA Jr, de Azambuja E, Francis P, Nordenskjöld B, Gutiérez J, Quinaux E, Mastropasqua MG, Ameye L, Anderson M, Lluch A, Gnant M, Goldhirsch A, Di Leo A, Barnadas A, Cortes-Funes H, Piccart M, Crown J Ten-year analyses of the BIG 2-98 phase III trial with an exploratory analysis on the role of Ki67 in predicting benefit of adjuvant docetaxel in patients with estrogen receptor positive breast cancer [submitted] IF: 370 Gnant M, Mlineritsch B, Stoeger H, Luschin-Ebengreuth G, Knauer M, Moik M, Jakesz R, Seifert M, Taucher S, BjelicRadisic V, Balic M, Eidtmann H, Eiermann W, Steger G, Kwasny W, Dubsky P, Selim U, Fitzal F, Hochreiner G, Wette V, Sevelda P, Ploner Bartsch R, with Fesl C, Greil R, on behalf of the ABCSGof tamoxifen versus anastrozole plus Zoledronic acidF,combined adjuvant endocrine therapy ovarian function suppression in premenopausal early breast cancer: of the Austrian Breast and Colorectal Cancer Ann Oncol 2015; 26; Study 313-20Group Trial 12 IF: 6,578 371 Gnant M, Sestak I, Filipits M, Dowsett M, Balic M, Lopez-Knowles E, Greil R, Dubsky P, Stoeger H, Rudas M, Jakesz R, Ferree S, Cowens JW, Nielsen T, Schaper C, Fesl C, Cuzick J Identifying clinically relevant prognostic subgroups of postmenopausal women with node-positive hormone receptor positive early stage breast cancer treated with endocrine therapy: A combined analysis ABCSG-8 and ATAC using the PAM50 risk of recurrence score and Intrinsic Subtype Ann Oncolof2015 [submitted] IF: 6,578 372 Eisterer W, De Vries A, Öfner D, Rabl H, Koplmüller R, Greil R, Tschmelitsch J, Schmid R, Kapp K, Lukas P, Sedlmayer F, Höfler G, Gnant M, Thaler J; ABCSG Preoperative treatment with capecitabine, cetuximab and radiotherapy for primary locally advanced rectal cancer--a phase II clinical trial. Anticancer Res 2014; 34: 6767-73 373 IF: 1,872 Gnant M, Steger GG, Bartsch R CDK4/6 inhibitors in luminal breast cancer Lancet Oncol 2015; 16: 2-3 374 IF: 24,725 Bartsch R, Berghof AS, Vogl U, Rudas M, Bergen E, Dubsky P, Dieckmann K, Pinker K, Bago-Horvath Z, Galid A, Oehler R, Zielinski CC, Gnant M, Steger GG, Preusser M Activity of T-DM1 in HER2-positive breast cancer brain metastases Neurooncology 2015 [submitted] 375 IF: 5,286 Markopoulos C, Neven P, Tanner M, Marty M, Kreienberg R, Atkins L, Franquet A, Gnant M, Neciosup S, Tesarova P, Barni S, Deschamp V Does patient education work in breast cancer? Final results from the global CARIATIDE study Future Oncol. 2015; 11: 205-17 376 IF: Hadji P*, Coleman RE*, Wilson C, Powles T, Clezardin P, Aapro M, Costa L, Body JJ, Markopoulos C, Santini D, Diel I, Di Leo A, Cameron D, Dodwell D, Smith I, Gnant M, Gray R, Harbeck N, Thuerlimann B, Untch M, Cortes J, Martin M, Albert US, Conte PF, Ejlertsen B, BerghinJ, early M Kaufmann, Holen. Consensus guidance for clinical practice from a Adjuvant bisphosphonates breast Icancer: European Panel. Ann Oncol 2015 [submitted] IF: 2