Prof. Dr. G. Elisabeth Pollerberg Department of
Werbung
Prof. Dr. G. Elisabeth Pollerberg Department of Developmental Neurobiology Institute of Zoology University of Heidelberg 69120 Heidelberg, Germany Phone: +49-(0)6221-54 6370 Fax: +49-(0)6221-54 63 75 E-mail: [email protected] 15/05/1955, Bochum CURRICULUM VITAE 1998 - present 1996 - 1998 1995 1989 – 1996 1986 - 1988 1982 - 1986 1979 1974 – 1978 Professor and Head of the Department of Developmental Neurobiology, Institute of Zoology, University of Heidelberg, Germany Professor at the Institute of Zoology, University of Giessen Habilitation in Developmental Biology, University of Tübingen Group Leader, Max-Planck-Institute for Developmental Biology, Tübingen PostDoc, Physical Instrumentation Programme, EMBL Heidelberg PhD, Institute of Neurobiology, University of Heidelberg Diploma Thesis, Developm. Physiology Dept., University of Konstanz Biology School, University of Konstanz COORDINATING FUNCTIONS 2002 - 2005 2000 - 2006 2000 - 2006 1999 - 2004 Speaker of the DFG Graduate School (GRK 484) "Signalling systems and gene expression in developmental biology model systems" Coordinator of the PhD-Programme of the Institute of Zoology Coordinator of the Federal State Examinations (Staatsexamen) Diploma Examination Committee FIELDS OF INTEREST Developmental Neurobiology, retina development, axon growth and regeneration, cell adhesion molecules, intracellular signalling components, cytoskeletal molecules CURRENTLY FUNDED PROJECTS SFB 488: Molecular and cellular basis of neural developmental processes", project B4; GRK 791: Neural developmental and degenerative processes; DFG project (PO 289): Role of cytoskeletal components for axon growth and navigation; Studienstiftung des Deutschen Volkes (Vorantrag befürwortet): Promotionsstipendium PUBLICATIONS (10 most important publications): Zelina P, Avci HX, Thelen K, Pollerberg GE (2005) Cell adhesion molecule NrCAM plays a role in axon growth and navigation in the visual system. Development, 132 (16), 3609-3618 Hahn, CM, Kleinholz H, Koester MP, Grieser S, Pollerberg GE (2005) Role of kinase Cdk5 and its activator P35 for axon stability and growth cone navigation. Neuroscience, 134,449-465 Avci HX, Zelina P, Thelen K, Pollerberg GE (2004) Role of cell adhesion molecule DMGRASP in growth and orientation of retinal ganglion cell axons. Dev. Biol., 271, 291-305 Hernandez-Sanchez C, Mansilla A, De la Rosa E,. Pollerberg GE, Martinez-Salas E, de Pablo F (2003) Upstream AUGs in the preproinsulin mRNA expressed in embryos specifically regulate translation. EMBO J., 22,5582-5592 Yamagata MA, Mai A, Pollerberg GE and Noda M (2000) Regulatory interrelations among topographic molecules CBF1, CBF2 and EphA3 in the developing chick retina. Dev. Growth Diff., 41, 575-587 Faivre-Sarrailh CF, Falk J, Pollerberg GE, Schachner M. and Rougon G (2000) NrCAM, cerebellar granule cell receptor for the neuronal cell adhesion molecule F3, displays an actindependent motility in growth cones. J Cell Sci., 112, 3015-3027 Mack TGA., Koester MP, Pollerberg GE (2000) The microtubule-associated protein MAP1B is involved in local stabilization of turning growth cones. Mol. Cell. Neurosci.15, 51-65 Stoeckli ET, Sonderegger P, Pollerberg GE, and Landmesser LT (1997) Interference with Axonin-1 and NrCAM interactions unmasks a floor plate activity inhibitory for commissural axons. Neuron, 18: 209-221. Pollerberg GE and Mack TGA (1994) Cell adhesion molecule DM-GRASP-GRASP is specifically expressed on growing, far projecting axons and mediates axonal tracking of retina ganglion cells. Dev. Biol., 165: 670-687 Pollerberg G. E., Schachner M, and Davoust J (1986) Surface mobilities of two molecular weight forms of the neural cell adhesion molecule N-CAM. Nature, London, 324: 462-465. EXPERIENCE IN THE SUPERVISION OF DOCTORAL CANDIDATES Speaker of the DFG Graduate School 484 Coordinator and author of PhD program of the Institute of Zoology Member of numerous thesis and thesis advisory committees (University and EMBL) International reviewer of doctoral theses Supervision of 28 doctoral theses since 1992 SUPERVISED DISSERTATIONS (last 5 years) Tobias Wolfram, PhD (2007) Neurale und neuronale Zelladhäsion, Zellproliferation und Zelldifferenzierung auf biofunktionalisierten 2-dimensionalen nanostrukturierten Oberflächen Current occupation: Postdoctoral fellow, Jackson Labs, Bar Habour Caroline Schmitz, PhD (2007) RNAi Screen anch Genen der axonalen Wegfindung und Charakterisierung der Funktion von Cadherin-4 in C. elegans Current occupation: Postdoctoral fellow, Vancouver, Canada Markus Seiler, PhD (2007) Das Programm 3of5 zur Suche nach komplexen Mustern in Proteinsequenzen Current occupation: Postdoctoral fellow, DKFZ, Heidelberg Ioannis Sotiropulos, PhD (2006) Cell and molecular biological aspect of steroidregulation of cytosleöetaö proteins with respect to Alzheimer’s disease Current occupation: Postdoctoral fellow, MPI München Hasan Avci, PhD (2005) The role of axonal cell adhesion molecules for axonal growth and orientation Current occupation: Postdoctoral fellow, CNRS Paris Susanne Kleber, PhD (2005) γ-Bestrahlung führt zu CD95-abhängiger Invasivität in apoptoseresistenten Glioblastomzellen Current occupation: unknown Pavol Zelina, PhD (2005) Functional analysis of NrCAM and DM-GRASP in the Chick embryo visual system Current occupation: Postdoctoral fellow, Yale Parag Kinge, PhD (2005) Large-Scale RNAi Screen to Identify Genes Involved in Axon Guidance in Caenorhabditis elegans Current occupation: unknown Valentin Schwarz, PhD (2005) Funktionelle Analyse der IgCAMs in der Nervensystementwicklung von caenorhabditis elegans Current occupation: unknown Ada, Cavalcanti-Adam, PhD (2005) The control of cell adhesion-dependent events by nanotemplates regulating the spatial arrangement of integrin ligands Current occupation: unknown Oliver Henschel, PhD (2004) Funktion der muskelspezifischen Kinase MuSK: Analyse durch konditionale Inaktivierung im transgenen Tiermodell Current occupation: unknown Christina Schmid, PhD (2004) Identifizierung und Charakterisierung von AST-1 in C. elegans, einem ETS Transkriptionsfaktor, der die axonale Wegfindung reguliert Current occupation: unknown Jan Christoph Peter, PhD (2003) Modulation der Aktivität des nikotinischen Acetylcholinrezeptors in transgenen Tiermodellen Current occupation: unknown Jörg Piontek, PhD (2002) Herstellung monoklonaler Antikörper gegen Proteine des neuronalen Membrankortes und Untersuchung von Gravin-Signalkomplexen in humanen Modell-Neuronen Current occupation: unknown
