Lebenslauf Prof. Dr. med. Jörg Haier, LL.M.
Werbung
Lebenslauf Prof. Dr. med. Jörg Haier, LL.M. Studium Humanmedizin, Humboldt - Universität zu Berlin (Charité), Diplommediziner Master Medizinrecht, Westfälische Wilhelms-Universität Münster Master Medizinrecht, LL.M. Gebietsanerkennung 2003; Facharzt für Chirurgie 2009; Zusatzbezeichnung Ärztliches Qualitätsmanagement Promotion 1993; Humboldt - Universität zu Berlin (Charité) Habilitation 2003, Medizinische Fakultät der Westfälischen Wilhelms-Universität Münster, Venia legendi für Chirurgie APL-Professur 2007; Medizinische Fakultät der Westfälischen Wilhelms-Universität Münster Univ.-Professur 2015; Medizinische Fakultät, Universitätsklinikum Hamburg-Eppendorf Aktuelle Positionen Direktor des Universitären Cancer Centers Hamburg Hubertur-Wald-Tumorzentrum Universitätsklinikum Hamburg-Eppendorf Adjunct Research Professor, Institute for Molecular Medicine, Huntington Beach, CA, USA Editorial Board: Clinical & Experimental Metastasis, seit 2005 Brit. J. Medical Practitioners, seit 2008 World J. Gastrointestinal Surgery, seit 2009 Cancers, seit 2009 Wissenschaftliche Auszeichungen: Studentenpreis 1986, Charitè, Berlin Stipendiat des DAAD, 1990 New Jersey Society for Colorectal Surgeons Award 1999; 100th Annual Conference of the American Society for Colorectal Surgeons, Washington Weitere wissenschaftliche Posterpreis Visiting Professorship: Universitas Muhammadiyah Yogyakarta, Indonesien, 2013, 2014 Funktionen: seit 2008, Vorstandsmitglied Arbeitsgemeinschaft Deutscher Tumorzenten (ADT) 2008-2015, Vorstandsmitglied Krebsgesellschaft NRW 2004, Kongresspräsident Chirurgische AG Qualitätssicherung Beruflicher Werdegang 2007-2015 Geschäftsführer und Koordinierender Direktor des Comprehensive Cancer Centers Münster (CCCM) des Universitätsklinikums Münster (UKM) 2009-2015 Leiter der Stabsstelle Internationales Patientenmanagement, UKM 2007–2008 Leiter der Sektion Chirurgische Endoskopie, UKM 2005–2008 Oberarzt der Klinik und Poliklinik für Allgemeine Chirurgie, UKM 1997–1999 Visiting Scientist und Research Assistant Professor, Institute for Molecular Medicine, Huntington Beach, CA, USA 1996–2001 Weiterbildungsassistent/wiss. Mitarbeiter in der Chirurgischen Klinik I, Universitätsklinikum B. Franklin, Freie Universität Berlin 1994 Weiterbildungsstipendium der Jung-Stiftung Chirurgische Universitätsklinik, Karls - Universität Heidelberg 1991–1996 Assistenzarzt, Abteilung Chirurgie und Chirurgische Onkologie der Robert - Rössle - Klinik, Humboldt - Universität zu Berlin Publikationsliste Jörg Haier Publikationsliste - J. Haier Publikationen - Originalarbeiten: 1. 2. Haier J, Hohenberger P, Schlag PM. Kontinuierliches Monitoring kardiozirkulatorischer Effekte der isolierten hyperthermen Extremitätenperfusion mit rhTNF alpha/Melphalan mit der Thermodilutionsmethode. (Continuous monitoring of cardiocirculatory effects during isolated hyperthermic limb perfusion with rhTNF alpha/Melphalan using thermodilution). Langenbecks Arch. Chir./ Chirurgisches Forum für experimentelle und klinische Forschung 1995: 251-257 14. Nicolson GL, Nasralla MY, Franco AR, De Meirleir K, Nicolson NL, Haier J. Role of Mycoplasmal Infections in Fatigue Illnesses: Chronic Fatigue and Fibromyalgia Syndromes, Gulf War Illness and Rheumatoid Arthritis. J. Chronic Fatigue Syndrome 1999; 12: 19-21 15. Haier J, Nicolson GL. Role of the cytoskeleton in adhesion stabilization of human colorectal carcinoma cells to extracellular matrix components under dynamic conditions of laminar flow. Clin. Exp. Metastasis 1999, 17: 713-721 Hohenberger P, Haier J, Schlag PM. Rhabdomyolysis and renal function impairment after isolated limb perfusion – Comparison between the effects of perfusion with rhTNFa and a “Triple-drug” regimen. Eur. J. Cancer 33; 1997: 596601 3. Haier J, Schön M, Hänsch W. Leiomyoma as a rare differential diagnosis of Paget’s disease of the nipple. Acta Obst. Gyn. Scand. 76; 1997: 490-491 4. Haier J, Hohenberger P, Beck K, Schlag PM. O2-Utilisation während und nach isolierter Extremitätenperfusion mit rhTNFα und melphalan (Oxygen utilisation during and after isolated limb perfusion with rhTNFα and melphalan). Langenbecks Arch. Chir. 382; 1997: 128-133 5. Hohenberger P, Haier J, Kettelhack CH, Schulze G, Schlag PM. Erfassung regionaler und systemischer Toxizität der isolierten, hyperthermen Extremitätenperfusion mit TumorNekrose-Faktor α und Melphalan (Assessment of regional and systemic toxicity of isolated limb perfusion with tumor necrosis factor-alpha and melphalan). Chirurg 1997; 68: 914-920 6. 13. Nasralla M, Haier J, Nicolson GL. Multiple Mycoplasmal Infections Detected in Blood of Chronic Fatigue Syndrome and Fibromyalgia Syndrome Patients. Eur J Clin Microbiol Infect Dis 1999; 18: 859-865 16. Haier J, Nicolson GL. Tumor cell adhesion of human colon carcinoma cells with different metastatic properties to extracellular matrix under dynamic conditions of laminar flow. J Cancer Res Clin Oncol, 2000, 126: 699-706 17. Haier J, Nicolson GL. Time-dependent dephosphorylation through Serine/Threonine phosphatases is required for stable adhesion of highly and poorly metastatic HT-29 colon carcinoma cell lines to collagen. Anticancer Res. 2000; 20: 2265-2271 18. Nasralla MY, Haier J, Nicolson GL. Examination of mycoplasmas in blood of 565 Chronic Illness patients by polymerase chain reaction. Int. J. Med. Biol. Environ. 28(1): 15-23 (2000). 19. Nicolson GL, Nasralla M, Franco AR, De Meirleir K, Nicolson NL, Ngwenya R, Haier J. Mycoplasmal infections in fatigue illnesses: Chronic Fatigue and Fibromyalgia Syndromes, Gulf War Illness and Rheumatoid Arthritis. J Chronic Fatigue Syndr 2000; 6(3/4):23-39. Haier J, Nasralla M, Buhr HJ, Nicolson GL. Differente Integrin-vermittelte Adhäsion von hoch hepatisch metastasierenden und gering metastasierenden ColonCarcinom-Zellen an extrazellulärer Matrix (Different integrinmediated adhesion of poorly and highly metastatic colon carcinoma cell lines on extracellular matrix). Langenbecks Arch. Chir./ Chirurgisches Forum für experimentelle und klinische Forschung 1998; 383: 307-313 20. Haier J, Gallick GE, Buhr HJ, Nicolson GL. Adhesion stabilization of HT-29 colon carcinoma cells to extracellular matrix is regulated by pp60src under dynamic conditions of laminar flow. Owen Wangensteen Surgical Forum, 2000, Vol LI, 260-262 7. Nicolson GL, Nasralla M, Haier J, Nicolson NL. Diagnosis and treatment of chronic mycoplasmal infections in fibromyalgia and chronic fatigue syndromes: Relationship to gulf war illness. Biomedical Therapy, 1998; 16: 266-271 8. Haier J, Nasralla M, Franco AR, Nicolson GL. Detection of mycoplasmal infections in blood of patients with Rheumatoid Arthritis. Rheumatol 1999; 38: 504-509. 9. Haier J, Nasralla M, Nicolson GL. Different adhesion properties of highly and poorly metastatic HT-29 colon carcinoma cells with extracellular matrix components: Role of integrin expression and cytoskeletal components. Brit. J. Cancer 1999; 80: 1867-1874 21. Haier J, Buhr HJ, Nicolson GL. Focal Adhesion Kinase (FAK) reguliert Zelladhäsion von HT-29 Kolon-Karzinomzellen an extrazellulärer Matrix unter hydrodynamischen Flowbedingungen. (Focal adhesion kinase (FAK) regulates cell adhesion of HT-29 colon carcinoma cells to extracellular matrix under hydrodynamic conditions of fluid flow.) Langenbecks Arch. Surg./ Surgical Forum for Experimental Research 2001; 30: 55-57 22. Kruschewski M, Noske A, Haier J, Runkel N, Anagnostopoulos Y, Buhr HJ. Is reduced expression of mismatch repair genes MLH1 and MSH2 in patients with sporadic colorectal cancer related to their prognosis? Clin. Exp. Metastasis 2002; 19(1): 71-77 23. Haier J, Nicolson GL. PTEN regulates tumor cell adhesion of colon carcinoma cells under dynamic conditions of fluid flow. Oncogene, 2002; 21(9): 1450-1460 10. Haier J, Nasralla M, Nicolson GL. Influence of phosphotyrosine kinase inhibitors on adhesive properties of highly and poorly metastatic HT-29 colon carcinoma cells to collagen. Int. J. Colorect. Dis. 1999; 14: 119-127 24. Haier J, Senninger N, Nicolson GL. The tumor suppressor PTEN regulates metastatic tumor cell adhesion of colon carcinoma cells. Langenbecks Arch. Surg./ Surgical Forum for Experimental Research, 2002, 31, 11. Haier J, Nasralla M, Nicolson GL. β1-integrin mediated dynamic adhesion of colon carcinoma cells to extracellular matrix under laminar flow. Clin. Exp. Metastasis 1999; 17: 377-388 25. Haier J, Gallick GE, Nicolson GL. Src protein kinase pp60c-src influences adhesion stabilization of HT-29 colon carcinoma cells to extracellular matrix components under dynamic conditions of laminar flow. J. Exp. Ther. Oncol., 2002; 2: 237245 12. Nicolson GL, Nasralla MY, Haier J, Erwin R, Nicolson NL, Ngwenya R: Mycoplasmal infections in chronic illnesses: Fibromyalgia and chronic fatigue syndromes, Gulf War illness, HIV-AIDS and rheumatoid arthritis. Medical Sentinel 1999; 4: 172-175. 26. Haier J, Goldmann U, Hotz B, Runkel N, Keilholz N. Inhibition of tumor progression and neoangiogenesis using cyclic RGDpeptides in a chemically induced colon carcinoma in rats. Clin. Exp. Metastasis, 2002, 19: 665-672 1 Publikationsliste Jörg Haier 27. Nicolson GL, Nasralla M, Haier J, Pomfret J. High frequency 43. Ciarimboli G, Ludwig T, Lang D, Koepsell H, Piechota HJ , of systemic mycoplasmal infections in Gulf War veterans and Haier J, Schlatter E. Cisplatin nephrotoxicity is related to civilians with Amyotrophic Lateral Sclerosis (ALS). J Clin uptake in human proximal tubules via the organic cation Neurosci. 2002; 5: 525-529 transporter hOCT2. Am. J. Pathol. 2005 ; 167: 1477-1484 28. Nicolson GL, Berns P, Nasralla MY, Haier J, Nicolson NL, Nass M. Gulf War Illnesses: Chemical, Biological and Radiological Exposures Resulting in Chronic Fatigue Illnesses. J Chronic Fatigue Syndr, 2003; 11: 135-154 44. Kriegeskotte C, Möller J, Lipinsky D, Wittig A, Sauerwein W, Haier J, Arlinghaus HF. Imaging of atomic and molecular species in tissue with laser-SNMS for pharmaceutical studies. Surf. Interface Anal. 2006; 38: 121–125 29. Nicolson GL, Nasralla M, Nicolson NL, Haier J. High Prevalence of Mycoplasmal Infections in Symptomatic (Chronic Fatigue Syndrome) Family Members of Mycoplasma-Positive Gulf War Illness Patients. J Chronic Fatigue Syndr 2003; 11:176-191. 45. Schlüter K, Korb T, Enns A, Gassmann P, Spiegel HU, Senninger N, Haier J. Organ-specific metastatic tumor cell adhesion correlates with metastasis formation. Am. J. Pathol. 2006; 169: 1064-1073 30. Nicolson GL, Nasralla M, Gan R, Haier J, De Meirleir K. Evidence for bacterial (mycoplasma, Chlamydia) and viral (HHV-6) co-infections in chronic fatigue syndrome patients. J. Chronic Fatigue Syndr. 2003; 11:162-175. 31. Haier J, Korb T, Hotz B, Spiegel HU, Senninger N. An intravital model to monitor steps of metastatic tumor cell adhesion within the hepatic microcirculation. J Gastrointest. Surg. 2003; 7: 507-515 32. Brockmann JG, Hernandez CA, Emparan C, Wolters H, Haier J, Dietl KH, Senninger NJ. Trypsinogen activation peptide (TAP) expression in gallbladder bile identifies biliopancreatic carcinoma. Anticancer Res. 2003; 23: 819-826 33. Nicolson GL, Gan R, Haier J. Multiple co-infections (mycoplasma, Chlamydia, human herpes-6) in blood of chronic fatigue syndrome patients. APMIS 2003; 111: 557566. 34. Kunze U, Ganslandt T, Preusser P, Bürkle T, Prokosch HU, Senninger N, Haier J. Ein interdisziplinäres Modul zur onkologischen Dokumentation in einem Klinikinformationssystem. Zentralbl Chir, 2004; 129: 10-13 35. Korb T, Schlüter K, Enns A, Spiegel HU, Senninger N, Nicolson GL, Haier J. Integrity of actin fibres and microtubules influences metastatic tumor cell adhesion. Exp. Cell Res., 2004; 299: 236-247 46. Mader R, Kocher Th, Haier J, Wieczorek G, Pfannkuche HJ, Ito M. Investigation of 5-HT4 receptor expression in human and non-human primate gastrointestinal samples. Eur. J. Gastroenterol. Hepatol. 2006; 9: 945-950 47. Haier J, Owzcareck M, Guller U, Spagnoli GC, Burger H, Senninger N, Kocher T. Expression of MAGE-A cancer/testis antigens in esophageal squamous cell carcinomas. Anticancer Res. 2006; 26: 2281-2287 48. Rodel C, Liersch T, Hermann R, Arnold D, Reese T, Hipp M, Furst A, Schwella N, Bieker M, Hellmich G, Ewald E, Haier J, Lordick F, Flentje M, Sülberg H, Hohenberger W, Sauer R. Multicenter Phase II Trial of the German Rectal Cancer Study Group: Preoperative Radiation with Concomitant and Adjuvant Capecitabine and Oxaliplatin for Rectal Cancer. J Clin Oncol, 2007; 25: 110-117 49. Nicolson GL, Gan R, Nicolson NL, Haier J. Evidence for Mycoplasma ssp., Chlamydia pneunomiae and Human Herpes Virus-6 Co-Infections in the Blood of Patients with Autistic Spectrum Disorders. J. Neuroscience Res, 2007, 85:11431148 50. Küpper S, Mees ST, Gassmann P, Brodde MF, Kehrel B, Haier J. Hydroxyethyl starch normalizes platelet and leukocyte adhesion within pulmonary microcirculation during lipopolysaccharide induced endotoxemia. Shock, 2007, 28:300-308 36. Enns A, Gassmann P, Korb T, Schlüter K, Spiegel HU, Senninger N, Haier J. Integrins can directly mediate metastatic tumor cell adhesion within the liver sinusoids. J Gastrointest Surg, 2004; 8:1049-1060 51. Palmes D, Röttgermann S, Classen C, Haier J, Horstmann R. Randomized clinical trial of the influence of intraperitoneal applied local anaesthesia in laparoscopic surgery on postoperative analgesic requirement and pain intensity. Br. J. Surg, 2007 ; 94 : 824-832 37. Beauchamp RD, Arnoletti, Haier J, et al. Mechanisms of resistance to erbitux (anti-epidermal growth factor receptor) combination therapy in pancreatic adenocarcinoma cells. J Gastrointest Surg, 2004; 8: 969-970 52. Bahde R, Palmes D, Minin E, Stratmann U, Diller R, Haier J, Spiegel HU. Bromelain Ameliorates Hepatic Microcirculation After Warm Ischemia. J Surg Res. 2007, 139: 88-96 38. Müthing J, Meisen I, Kniep B, Haier J, Senninger N, Neumann U, Langer U, Witthohn K, Milosevic J, PeterKatalinic J. Tumor-associated CD75s-gangliosides and CD75s-bearing glycoproteins with Neu5Acalpha26Galbeta1-4GlcNAc-residues are receptors for the anticancer drug rViscumin. FASEB J, 2005; 19: 103-105 39. von Sengbusch A, Gassmann P, Fisch K, Enns A, Nicolson GL, Haier J. Focal Adhesion Kinase regulates dynamic adhesion of carcinoma cells to collagens. Am. J. Pathol., 2005; 166: 585-593 40. Enns A, Korb T, Schlüter K, Spiegel HU, Senninger N, Mitjans F, Haier J. αvβ5-integrins mediate early steps of metastasis formation. Eur. J. Cancer, 2005; 41: 1065-1072 41. Nicolson GL, Berns P, Gan R, Haier J. Chronic Mycoplasmal Infections in Gulf War Veterans’ Children and Autism Patients. Medical Veritas, 2005; 2: 383-387 42. Nicolson GL, Gan R, Haier J. Evidence for Brucella spp. and Mycoplasma spp. co-infections in the blood of chronic fatigue syndrome patients. J. Chronic Fatigue Syndr. 2004; 12: 5-17 53. Bembenek A; Rosenberg R; Wagler E; Gretschel S; Sendler A; Siewert, JR; Nahrig J; Witzigmann H; Hauss J; Knorr C; Dimmler A; Grone J; Buhr HJ; Haier J; Herbst H; Tepel J; Siphos B; Kleespies A; Koenigsrainer A; Stoecklein N; Horstmann O; Grutzmann R; Imdahl A; Svoboda D; Wittekind W; Schneider W; Wernecke KD; Schlag PM. Sentinel Lymph Node Biopsy in Colon Cancer: A Prospective Multicenter Trial. Ann Surg 2007; 245: 858-863 54. Mees ST, Gwinner M, Marx K, Faendrich F, Schroeder J, Haier J, Kahlke V. Influence of sex and age on morphological organ damage after hemorrhageic shock. Shock, 2008, 29(6):670-4. 55. Vogel T, Vadonis R, Kühn J, Eing BR, Senninger N, Haier J. Viral reactivation is not related to septic complications after major surgical resections. APMIS 2008, 116(4):292-301 56. Rosenow F, Ossig R, Thormeyer D , Gaßmann P, Schlüter K, Brunner G, Haier J, Eble JA. Integrins as antimetastatic targets of RGD-independent snake venom components in liver metastasis. Neoplasia 2008, 10(2):168-76 2 Publikationsliste Jörg Haier 57. Distler U, Hülsewig M, Souady J, Dreisewerd K, Haier J, Senninger N, Friedrich A, Karch H, Hillenkamp F, Berkenkamp S, Peter-Katalinic J, Müthing J. Matching IRMALDI-o-TOF Mass Spectrometry with the TLC Overlay Binding Assay and its Clinical Application for Tracing Tumor-Associated Glycosphingolipids in Hepatocellular and Pancreatic Cancer. Analyt. Chem. 2008, 80(6):1835-46 58. Mees ST, Palmes D, Mennigen R, Tuebergen D, Senninger N, Haier J, Bruewer M. Endo-VAC treatment for rectal anastomotic insufficiency. Dis Colon Rectum, 2008, 51(4):404-10 59. Sidler D, Studer P, Küpper S, Gloor B, Candinas D, Haier J, Inderbitzin D. Granulocyte colony-stimulating factor increases hepatic sinusoidal perfusion during liver regeneration in mice. J Invest Surg. 2008;21(2):57-64 60. Distler U, Souady J, Hülsewig M, Drmić-Hofman I, Haier J, Denz A, Grützmann R, Pilarsky C, Senninger N, Dreisewerd K, Berkenkamp S, Schmidt MA, Peter-Katalinic J, Müthing J. Tumor-associated CD75s- and iso-CD75s-gangliosides are potential targets for adjuvant therapy in pancreatic cancer. Mol Cancer Ther. 2008; 7: 2464-2475 61. Mees ST, Mennigen R, Spieker T, Rijcken E, Senninger N, Haier J, Bruewer M. Expression of tight and adherens junction proteins in ulcerative colitis associated colorectal carcinoma: upregulation of claudin-1, claudin-3, claudin-4, and beta-catenin. Int J Colorectal Dis. 2009; 24(4): 361-368 70. Mees ST, Mardin WA, Wendel C, Baeumer N, Willscher E, Senninger N, Schleicher C, Colombo-Benkmann M, Haier J. EP300 - a miRNA-regulated metastasis suppressor gene in ductal adenocarcinomas of the pancreas. Int J Cancer. 2010 Jan 1;126(1):114-24. doi: 10.1002/ijc.24695 71. Mees ST, Kebschull L, Senninger N, Wolters H, Haier J. Nachweis virusspezifischer T-Zellen bei Patienten nach allogener Nierentransplantation. Transplantationsmedizin 2010; 22: 123-127 72. Gassmann P, Kang ML, Mees ST, Haier J. In vivo tumor cell adhesion in the pulmonary microvasculature is exclusively mediated by tumor cell - endothelial cell interaction. BMC Cancer. 2010;10:177. 73. Gassmann P, Spieker T, Haier J, Schmidt F, Mardin WA, Senninger N. Prognostic Impact of Underlying Liver Fibrosis and Cirrhosis After Curative Resection of Hepatocellular Carcinoma. World J Surg. 2010; 34; 2442-2451 74. Hummel R, Hussey DJ, Michael MZ, Haier J, Bruewer M, Senninger N, Watson DI. MiRNAs and Their Association with Locoregional Staging and Survival Following Surgery for Esophageal Carcinoma. Ann Surg Oncol. 2011 Jan;18(1):25360. doi: 10.1245/s10434-010-1213-y 75. Mardin WA, Petrov KO, Enns A, Senninger N, Haier J, Mees ST. SERPINB5 and AKAP12 -- Expression and Promoter Methylation of Metastasis Suppressor Genes in pancreatic ductal Adenocarcinoma. BMC Cancer. 2010 Oct 12;10:549 62. Deitmar S, Anthoni C, Palmes D, Haier J, Senninger N, 76. Souady J, Hülsewig M, Distler U, Haier J, Denz A, Pilarsky C, Brüwer M. Are Leukocytes and CRP Early Indicators for Senninger N, Dreisewerd K, Peter-Katalinic J, Müthing J. Anastomotic Leakage after Esophageal Resection? Zentralbl Differences in CD75s- and iso-CD75s-ganglioside content and Chir. 2009; 134(1): 83-89 altered mRNA expression of sialyltransferases ST6GAL1 and 63. Mees ST, Mardin WA, Sielker S, Willscher E, Senninger N, ST3GAL6 in human hepatocellular carcinoma and non-tumoral Schleicher C, Colombo-Benkmann M, Haier J. Involvement liver tissues. Glycobiology. 2011 May;21(5):584-94. Epub 2010 of CD40 Targeting miR-224 and miR-486 on the Progression Dec 7 of Pancreatic Ductal Adenocarcinomas. Ann Surg Oncol. 77. Hummel R, Watson DI, Smith C, Kist J, Michael MZ, Haier J, 2009 Aug;16(8):2339-50. doi: 10.1245/s10434-009-0531-4 Hussey DJ. MiR-148a improves response to chemotherapy in 64. Gassmann P, Haier J, Schlüter K, Domikowsky B, Wendel sensitive and resistant esophageal adeno and squamous cell C, Wiesner U, Kubitza R, Engers R, Schneider SW, Homey carcinoma cells. J Gastrointest Surg. 2011 Mar;15(3):429-38. B, Müller A.. CXCR4 regulates the early extravasation of Epub 2011 Jan 19. metastatic tumor cells in vivo. Neoplasia 2009; 11: 651-661 78. Hummel R, Wang T, Watson DI, Michael MZ, Van der Hoek M, 65. Gassmann P, Hemping-Bovenkerk A, Mees T, Haier J. Haier J, Hussey DJ. Chemotherapy-induced modification of Metastatic tumor cell arrest in the liver-lumen occlusion and microRNA expression in esophageal cancer. Oncol Rep. 2011; specific adhesion are not exclusive. . Int J Colorectal Dis. 26: 1011-1017. doi: 10.3892/or.2011.1381. 2009 Jul;24(7):851-8. 79. Mees ST, Schleicher C, Mardin WA, Senninger N, Colombo66. Mees ST, Toellner S, Marx K, Faendrich F, Kallen KJ, Benkmann M, Haier J. Analyzing miRNAs in Ductal Schroeder J, Haier J, Kahlke V. Inhibition of Interleukin-6Adenocarcinomas of the Pancreas. J Surg Res. 2011 Transsignaling via gp130-Fc in Hemorrhagic Shock and Aug;169(2):241-6. Sepsis. J Surg Res. 2009 Dec;157(2):235-42. doi: 80. Schweer C, Doering S, Haier J, Heuft G, Fritz F, Dugas M, 10.1016/j.jss.2008.08.035. Epub 2008 Sep 29 Schneider G. Psychoonkologische Angebote – was wünschen 67. Distler U, Souady J, Hülsewig M, Drmić-Hofman I, Haier J, über 60-jährige Krebspatienten? Z. Psychosom Med Friedrich AW, Karch H, Senninger N, Dreisewerd K, Psychother 2011; 57: 223-232 Berkenkamp S, Schmidt MA, Peter-Katalinić J, Müthing J. 81. Mees ST, Mardin WA, Schleicher C, Colombo-Benkmann M, Shiga toxin receptor Gb3Cer/CD77: tumor-association and Senninger N, Haier J. Role of tumor microenvironment on promising therapeutic target in pancreas and colon cancer. gene expression in pancreatic cancer tumor models. J Surg PLoS One. 2009 Aug 28;4(8):e6813. Res. 2011 Nov;171(1):136-42 68. Kriegeskotte C, Cantz T, Haberland J, Zibert A, Haier J, 82. Wendel C, Hemping-Bovenkerk A, Krasnyanska J, Mees ST, Köhler G, Schöler HR, Schmidt HH, Arlinghaus HF. Laser Kochetkova M, Stoeppeler S, Haier J. CXCR4/CXCL12 secondary neutral mass spectrometry for copper detection in participate in extravasation of metastasizing breast cancer micro-scale biopsies. J Mass Spectrom. 2009 cells within the liver in a rat model. PLoS One. 2012; Oct;44(10):1417-22. 7(1):e30046. Epub 2012 Jan 13 69. Souady J, Soltwisch J, Dreisewerd K, Haier J, Peter83. Stahl O, Löffler B, Haier J, Mardin WA, Mees ST. Mimicry of Katalinić J, Müthing J. Structural profiling of individual human sepsis in a rat model - Prospects and limitations. J glycosphingolipids in a single thin-layer chromatogram by Surg Res. 2013 Jan;179(1):e167-75. doi: multiple sequential immunodetection matched with Direct IR10.1016/j.jss.2012.01.042. Epub 2012 Apr 1. MALDI-o-TOF mass spectrometry. Anal Chem. 2009 Nov 15;81(22):9481-92. 3 Publikationsliste Jörg Haier 84. Storck W, Meisen I, Gianmoena K, Pläger I, Kouzel I, Bielaszewska M, Haier J, Mormann M, Humpf HU, Karch H, Muething J. Shiga toxin glycosphingolipid receptor expression and toxin susceptibility of human pancreatic ductal adenocarcinomas of differing origin and differentiation. Biol Chem. 2012 Aug 1;393(8):785-99 96. Meier C, Spitschak A, Abshagen K, Gupta S, Mor JM, Wolkenhauer O, Haier J, Vollmar B, Alla V, Pützer BSM. Regulatory feedback loop between E2F1 and RHAMM promotes extravasation of circulating tumor cells. J Pathol. 2014 Nov;234(3):351-64. doi: 10.1002/path.4400. Epub 2014 Aug 28 85. Matthews P, Alpert M, Rahav G, Rill D, Zito E, Gardiner D, Pedersen R, Babinchak T, McGovern PC; Tigecycline 900 cSSSI Study Group. A randomized trial of tigecycline versus ampicillin-sulbactam or amoxicillin-clavulanate for the treatment of complicated skin and skin structure infections. BMC Infect Dis. 2012 Nov 12;12:297. doi: 10.1186/14712334-12-297 97. Lindner K, Borchardt C, Schöpp M, Bürgers A, Stock C, Hussey DJ, Haier J, Hummel R. Proton pump inhibitors (PPIs) impact on tumour cell survival metastatic potential and chemotherapy resistance and affect expression of resistancerelevant miRNAs in esophageal cancer. J Exp Clin Cancer Res. 2014, 33:73. DOI: 10.1186/s13046-014-0073-x 86. Funke K, Bonrath E, Mardin WA, Becker JC, Haier J, Senninger N, Vowinkel T, Hoelzen JP, Mees ST. Blended learning in surgery using the Inmedea Simulator. Langenbecks Arch Surg. 2013 Feb;398(2):335-40. doi: 10.1007/s00423-012-0987-8. 87. Maurer J, Schöpp M, Thurau K, Haier J, Köhler G, Hummel R. Immunohistochemical analysis on potential new molecular targets for esophageal cancer. Dis Esophagus. 2014; 27(1): 93-100. doi: 10.1111/dote.12065 88. Mardin WA, Haier J, Mees ST. Epigenetic regulation and role of metastasis suppressor genes in pancreatic ductal adenocarcinoma. BMC Cancer. 2013 May 29;13:264. doi: 10.1186/1471-2407-13-264 89. Bartsch F, Kang ML, Mees ST, HaierJ, Gassmann P. In Vivo Quantification of Metastatic Tumor Cell Adhesion in the Pulmonary Microvasculature In: Troy A. Baudino (ed.), CellCell Interactions: Methods and Protocols, Methods in Molecular Biology, 2013;1066:89-101. DOI 10.1007/978-162703-604-7_8 90. Vahle AK, Domikowsky B, Schwöppe C, Krähling H, Mally S, Schäfers M, Hermann S, Shahin V, Haier J, Schwab A, Stock C. Extracellular matrix composition and interstitial pH modulate NHE1-mediated melanoma cell motility. Int J Oncol. 2014 Jan;44(1):78-90. doi: 10.3892/ijo 91. Krumm R, Semjonow A, Tio J, Duhme H, Bürkle T, Haier J, Dugas M, Breil B. The Need for Harmonized Structured Documentation and Chances of Secondary Use - Results of a Systematic Analysis with Automated Form Comparison for Prostate and Breast Cancer. J Biomed Inform. 2014 Oct;51:86-99. doi: 10.1016/j.jbi.2014.04.008. Epub 2014 Apr 18 92. Mees ST, Kebschull L, Mardin WA, Senninger N, Suwelack B, Wolters H, Haier J. Detection of Different Virus-Specific CD8+ T Cells after Kidney Transplantation. Surg Infect (Larchmt). 2014 Jun;15(3):274-82. doi: 10.1089/sur.2013.083. Epub 2014 May 6 98. Listing H, Mardin W, Wohlfromm S, Mees T, Haier J. miR-23a/ -24 induced gene silencing results in mesothelial cell integration of pancreatic cancer. Br J Cancer. 2015 Jan 6;112(1):131-9. doi: 10.1038/bjc.2014.587. Epub 2014 Nov 25 99. Lindner K, Palmes D, Grübener A, Senninger N, Haier J, Hummel R. Esophageal cancer specific risk score is associated with postoperative complications following open Ivor-Lewis esophagectomy for adenocarcinoma. Dig Surg. 2016;33(1):58-65. doi: 10.1159/000439442. 100. Mardin WA, Ntalos D, Mees ST, Spieker T, Senninger N, Haier J, Dhayat SA. SERPINB5 Promoter Hypomethylation differentiates Pancreatic Ductal Adenocarcinoma from Pancreatitis. Pancreas. 2015 Dec 5. [Epub ahead of print] 101. Dhayat SA, Mardin WA, Seggewiß J, Ströse AJ, Matuszcak C, Hummel R, Senninger N, Mees ST, Haier J. MicroRNA Profiling Implies New Markers of Gemcitabine Chemoresistance in Mutant p53 Pancreatic Ductal Adenocarcinoma. PLoS One. 2015 Nov 25;10(11):e0143755. doi: 10.1371/journal.pone.0143755. eCollection 2015. 102. Dhayat SA, Hüsing A, Senninger N, Schmidt HH, Haier J, Wolters H, Kabar I. Circulating microRNA-200 Family as Diagnostic Marker in Hepatocellular Carcinoma. PLoS One. 2015 Oct 8;10(10):e0140066. doi: 10.1371/journal.pone.0140066. 103. Dhayat SA, Abdeen B, Köhler G, Senninger N, Haier J, Mardin WA. MicroRNA-100 and microRNA-21 as markers of survival and chemotherapy response in pancreatic ductal adenocarcinoma UICC stage II. Clin Epigenetics. 2015 Dec 23;7:132. doi: 10.1186/s13148-015-0166-1. eCollection 2015. Publikationen – Übersichtsarbeiten/Editorials 1. Haier J, Otto G, Herfarth Ch. Antithrombin III - Substitution in der Chirurgie. (Antithrombin III - Substitution in surgery). Aktuelle Chirurgie 1995; 30: 180-184 2. Haier J, Nasralla M, Nicolson GL. Cell surface molecules and their prognostic values in assessing colorectal carcinomas. Ann. Surgery 2000; 231: 11-24 93. Dhayat S, Mardin WA, Köhler G, Bahde R, Argyris I, 3. Vowinkel T, Wolters H, Senninger N, Haier J, Mees ST. The microRNA-200 family – a potential diagnostic marker in hepatocellular carcinoma? J Surg Oncol. 2014;110:430–438. doi: 10.1002/jso.23668 4. 94. Hummel R, Sie C, Watson DI, Wang T, Ansar A, Michael MZ, Van der Hoek M, Haier J, Hussey MJ. MicroRNA signatures in chemotherapy resistant esophageal cancer cell lines. World J Gastroenterol. 2014 Oct 28;20(40):14904-12. doi: 10.3748/wjg.v20.i40.14904 5. 95. Kettling H, Vens-Cappell S, Soltwisch J, Pirkl A, Haier J, Müthing J, Dreisewerd K. MALDI Mass Spectrometry Imaging of Bioactive Lipids in Mouse Brain with a Synapt G2-S Mass Spectrometer Operated at Elevated Pressure: Improving the Analytical Sensitivity and the Lateral Resolution to Ten Microns. Anal Chem. 2014 Aug 5;86(15):7798-805. doi: 10.1021/ac5017248. Epub 2014 Jul 22 Haier J, Nicolson GL. Prognostic value of cell surface molecules in colorectal carcinomas. [Prognostischer Wert von Zelloberflächenmolekülen bei kolorektalen Karzinomen.] Visceralchirurgie 2000, 35, 172-181 Haier J, Nicolson GL. Cell Biology and clinical implications of adhesion molecules in colorectal diseases: colorectal cancers, infections and inflammatory bowel diseases. Clin. Exp. Metastasis, 2001, 18(8): 623-638 Haier J, Nicolson GL. The role of tumor cell adhesion as an important factor in formation of distant colorectal metastasis. Dis Colon Rect, 2001, 44(6):876-884 6. Haier J, Nicolson GL. Tumor cell adhesion under hydrodynamic conditions of fluid flow. APMIS, 2001, 109: 241262 7. Haier J, Nicolson GL. Cell surface molecules as indicators of prognosis in colorectal carcinomas. New Surgery 2001; 1: 152157 4 Publikationsliste Jörg Haier 8. 9. Haier J, Senninger N. Neoadjuvante Chemotherapie, mehrzeitige Leberresektionen und präoperative portale Embolisation bei primären und sekundären Lebertumoren. Onkologe 2001; 7: 1244-1246 Gaßmann P, Haier J, Senninger N. MUC1 als Marker zum molekularen Staging cholangiozellulärer Karzinome Onkologe 2002; 10: 1114-1115 Publikationen – Medizinrecht/Gesundheitsökonomie 1. Haier J. (K)ein notwendiges Übel? Forschungsausbildung in der Weiterbildung. Management & Krankenhaus, 2006, (12), 11 2. Haier J, Berdel W, Roeder N. New developments in tumor medicine: New structure of integrated tumor medicine at the University Hospital Münster. Das Krankenhaus 04.2009, 323327 3. Haier J. Data management in integrated cancer centers: Structure and data flow models for different interests. Dtsch Arztebl 2009; 106(21): A-1040 4. Haier J. Qualitätsindikatoren in der Onkologie. Quo vadis? Das Krankenhaus, 2011, 103: 882-886 5. Haier, J, Ückert F. Wieviel Biobank braucht die Forschung? Spannungsfeld zwischen Forschungsfreiheit, Selbstbestimmung und ethischer Verpflichtung. Gesundh . ökon. Qual.manag. 2012; 17: 97-102 6. Haier J. Wann ist ein Zentrum ein “Zentrum”? – Gegenläufige Urteile von BVerfG und BGH: Konsequenzen für die Krankenhäuser. KU Gesundheitsmanagement 2012, 81 (12): 35-37 7. Ott R, Haier J. Aus der Not eine Tugend machen: Wie sich Pharmaunternehmen als Partner der Krankenhäuser etablieren können. Market Access & Health Policy, 2012, Heft 6, 26-27 8. Haier J, Bergmann KO. Medizinrechtliche Aspekte von Tumorboards. Chirurg. 2013 Mar;84(3):225-30. doi: 10.1007/s00104-013-2481-4. 9. Haier J, Bergmann K. Rechtliche Verantwortlichkeit patientenferner Entscheider in Krankenhäusern (I). Das Krankenhaus, 2013, Heft 8, 828-834 10. Haier J, Senninger N. Klinischer Nutzen der intraoperativen Sentinel-Lymphknoten-Biopsie beim Magenkarzinom. Onkologe 2003; 11: 1270-1271 11. Schleicher C, Haier J, Senninger N. Operationsrisiko nach neoadjuvanter Therapie gastrointestinaler Karzinome. Onkologe, 2003; 9: 1383-1401 12. Haier J. Genexpressionsprofile von Kolonkarzinomen: Korrelation mit histologischen und klinischen Parametern. Onkologe 2004; 10: 525-526 13. Gassmann P, Enns A, Haier J. Role of Tumor Cell Adhesion and Migration in specific Metastasis Formation. Onkologie 2004; 27: 577-582 14. Senninger N, Krieglstein CF, Haier J. Preface. Transplant. Proc. 2005; 37: 1593 15. Eble JA, Haier J. Integrins in cancer treatment. Current Cancer Drug Targets 2006: 6: 89-105 16. Gaßmann P, Haier J. The tumor cell-host organ interface in the early onset of metastatic organ colonisation. Clin. Exp. Metastasis 2008, 25(2):171-81 17. Nicolson GL, Haier J. Role of Chronic Bacterial and Viral Infections in Neurodegenerative, Neurobehavioral, Psychiatric, Autoimmune and Fatiguing Illnesses: Part 1. BJMP 2010; 2: 20-28 18. Nicolson GL, Haier J. Role of Chronic Bacterial and Viral Infections in Neurodegenerative, Neurobehavioral, Psychiatric, Autoimmune and Fatiguing Illnesses: Part 2. BJMP 2010; 3: 301-310 19. Hummel R, Hussey DJ, Haier J. MicroRNAs: Predictors and modifiers of chemo- and radiotherapy in different tumour types. Eur. J. Cancer 2010: 46: 298-311 20. Dhayat S, Mardin W, Mees S, Haier J. Epigenetic markers for chemosensitivity and chemoresistance in pancreatic cancer – A Review. Int J Cancer. 2011 Sep 1;129(5):103141 21. Dhayat S, Mardin W, Mees S, Haier J. Cover Page. Int. J. Cancer, 2011; 129 (9) 22. Hummel R, Maurer J, Haier J. MicroRNAs in Brain Tumors: A New Diagnostic and Therapeutic Perspective? Mol Neurobiol. 2011; 44: 223-234 23. Haier J, Gassmann P. Current Concepts of Metastasis Formation (Editorial). Cancers 2011, 3(3), 2886-2887 24. Matuszcak C, Haier J, Hummel R, Lindner K. MicroRNAs: promising biomarkers for chemoresistance in gastric cancer with diagnostic and therapeutic potential. World J Gastroenterol. 2014 Oct 14;20(38):13658-66. doi: 10.3748/wjg.v20.i38.13658 10. Haier J, Bergmann K. Sorgfaltspflichten patientenferner Entscheider in Krankenhäusern (II). Sorgfaltspflichten, Das Krankenhaus, 2013, Heft 10, 1036-1040 11. Haier J, Bergmann K. Rechtliche Verantwortlichkeit patientenferner Entscheider in Krankenhäusern (III). Die Haftung übergeordneter Kommissionen und die Organisationsverantwortung. Das Krankenhaus, 2013, Heft 11, 1120-1126 12. Haier J. Gegenwärtige rechtliche Rahmenbedingungen für den Betrieb und die Nutzung von Biobanken. Teil 1: Rechtsgrundlagen, Chirurg. 2013 Sep;84(9):785-93. doi: 10.1007/s00104-013-2606-9 13. Haier J. Gegenwärtige rechtliche Rahmenbedingungen für den Betrieb und die Nutzung von Biobanken. Teil 2: Datenschutz bei Biobanken, Chirurg. 2013 Oct;84(10):892-901. doi: 10.1007/s00104-013-2607-8 14. Haier J, Möslein G. Das Krebsregistergesetz als Teil des Nationalen Krebsplans. Der Onkologe, 2013, 19: 1037-1046. 10.1007/s00761-013-2517-x 15. Möslein G, Haier J, Schlag PM. Einführung zum Thema: Klinische und epidemiologische Krebsregister? Krebsregister in Deutschland – qou vadis. Der Onkologe, 2013, 19: 10221024 25. Lindner K, Haier J, Wang Z, Watson DI, Hussey DJ, Hummel 16. Haier J. Das Patientenrechtegesetz: Bedeutung im Alltag R. Circulating microRNAs: emerging biomarkers for operativer Disziplinen. Dtsch Med Wochenschr. 2014 diagnosis and prognosis in patients with gastrointestinal Jan;139(1-2):47-52. doi: 10.1055/s-0033-1359881 cancers. Clin Sci (Lond). 2015 Jan 1;128(1):1-15. doi: 10.1042/CS20140089. 17. Haier J. Gegenwärtige rechtliche Rahmenbedingungen für den Betrieb und die Nutzung von Biobanken Teil 3: Eigentum und 26. Haier J, Ströse A, Matuszcak C, Hummel R. miR clusters Nutzungsrechte, Chirurg. 2014 Oct;85(10):918-28. doi: target cellular functional complexes by defining their degree 10.1007/s00104-014-2813-z of regulatory freedom. Can Met Rev, 2016, in press 5 Publikationsliste Jörg Haier 18. Arnholdt J, Haier J. Kostentrend Klinischer Prüfungen: Ergebnisse einer Vertragsanalyse. Gesundh . ökon. Qual.manag. 2014, DOI: 10.1055/s-0034-1366824 19. Haier J, Mardin WA. How does biobanking affect the patientphysician relationship? Future Med, 2016 in press 20. Haier J, Bamberg M. Editorial: Klinische Onkologie im stetigen Wandel. Der Onkologe, 2016, Heft 1, in press 21. Haier J. Tasks and Limitations of Tumor Boards [Aufgaben und Grenzen von Tumorkonferenzen]. Der Onkologe, 2016, in press Guest Editor: 1. Transplantation Proceedings 2005; 37: Issue 3 2. Cancers 2011, 3: Issue 3: Current Concepts of Metastasis Formation. 3. Der Onkologe, Themenheft Klinische Krebsregister, 2013, Heft 11 4. Der Onkologe, Themenheft Struktur und Organisation der klinischen Onkologie, 2016, Heft 1 Bücher: 1. Alison M, Nicolson GL, Haier J, et al.: Cancer Handbook, Macmillan, London, 2001 2. Alison M, Haier J, et al.: Cancer Handbook 2nd ed., Wiley & Sons, London, 2007 Buchbeiträge: 1. Haier J, Schlag PM. Karzinome der Gallenblase und der Gallenwege (Carcinoma of gall bladder and bile duct). In: Angewandte Onkologie (Hrsg. P. M. Schlag), Springer Heidelberg Berlin New York Tokyo, 1995 3. Haier J. Indikation und Strategie der operativen Therapie von Fernmetastasen kolorektaler Karzinome (Indication and strategy of surgical treatment in metastatic colorectal cancer). In: Operationskurs: Kolorektales Karzinom (Hrsg. H.-J. Buhr, N. Runkel), Ambrosius Barth Verlag, Leipzig, 1997, 138-145 11. Fisch KM, von Sengbusch A, Schlüter A, Haier J. Inhibition früher Schritte der Metastasierung durch Blockade von FAK (Focal Adhesion Kinase) in vivo. Chirurgisches Forum 2005, Band 34: Hrsg.: M. Rothmund, K.-W. Jauch, H. Bauer; Springer-Verlag 12. Gaßmann P, Enns A, Spiegel HU, Haier J. Organspezifische Adhäsion metastatischer humaner Kolonkarzinomzellen in unterschiedlichen Targetorganen in vivo. Chirurgisches Forum 2005, Band 34: 75-76; Hrsg.: M. Rothmund, K.-W. Jauch, H. Bauer; Springer-Verlag 2005 13. Enns A, Gaßmann P, Spiegel HU, Haier J. Ein neues Modell zur Quantifizierung der Turmorzellmigration in vivo. Chirurgisches Forum 2005, Band 34: 71-73; Hrsg.: M. Rothmund, K.-W. Jauch, H. Bauer; Springer-Verlag 2005 14. Gassmann P, Haier J. Molecular mechanisms of cancer metastasis. In: G. V. Sherbet (ed.) The Molecular and Cellular Pathology of Cancer Progression and Prognosis, Research Signpost, Kerala, India, 2006: 1-52 15. Gassmann P, Haier, J., Nicolson, G.L. Cell adhesion and invasion during secondary tumor formation. In: Cancer Growth and Progression, vol. 3, Kluwer, Amsterdam, (2005). 16. Krasnyanska J, Gaßmann P, Haier J. Wachstumsfaktoren steigern die trajektorielle chemotaktische Tumorzellmigration in Abhängigkeit von der extrazellulären Matrix. Chirurgisches Forum 2006, Band 35: 89-91; Hrsg.: H.-D. Saeger, K.-W. Jauch, H. Bauer; Springer-Verlag 2006 17. Enns A, Haier J. Hereditäre kolorektale Erkrankungen. Stand, Indikation und klinische Konsequenzen genetischer Untersuchungen. In: Chirurgie von Kolon und Rektum (Hrsg: Colombo-Benkmann M, Senninger N), Lehmanns Media, Berlin, 2006: 48-59 18. Haier J, Sulkowski U. Allgemeinchirurgie. In: Jahn U, van Aken HK, Zusatzweiterbildung Intensivmedizin, Thieme Stuttgart, 2006, 91-128 19. Gassmann P, Nicolson GL, Haier J. Models for tumor cell – endothelial cells interactions. The Cancer Handbook, 2nd edition, editor-in-chief: Malcolm R. Alison, John Wiley & Sons Ltd.,Chichester 2007; ISBN-13 978-0-470-01852-1 4. Nasralla M, Haier J, Nicolson GL. Mycoplasmal Infections in Blood from Patients with Chronic Fatigue Syndrome, Fibromyalgia Syndrome or Gulf War Illness. Proceedings of International CFS Conference, Sydney, Australia, 1998 20. Haier J, Nicolson GL. Advantages and Limitations of Models for Cancer and Malignant Cell Progression. The Cancer Handbook, 2nd edition, editor-in-chief: Malcolm R. Alison, John Wiley & Sons Ltd.,Chichester 2007; ISBN-13 978-0-470-01852-1 5. Haier J, Nicolson GL. Role of the Vascular Endothelium in Cancer Metastasis. In: Intramolecular Cross-talk in Metastasis, (G. Skouteris and G. L. Nicolson, Eds.), NATO ASI series, IOS Press, Amsterdam, 225-249 (1999). 21. Cavanaugh P, Haier J. Basic Tissue and Cell Culture in Cancer Research The Cancer Handbook, 2nd edition, editor-in-chief: Malcolm R. Alison, John Wiley & Sons Ltd.,Chichester 2007; ISBN-13 978-0-470-01852-1 6. Nicolson GL, Nasralla M, Haier J, Nicolson NL. Gulf war illnesses: Role of chemical, radiological and biological exposures. In: War or Health, Taipale I et al, eds., Zed Books, London & New York, 2001, 431-446. 22. Clarke R, Haier J. Human tumors in animal hosts. The Cancer Handbook, 2nd edition, editor-in-chief: Malcolm R. Alison, John Wiley & Sons Ltd.,Chichester 2007; ISBN-13 978-0-470-018521 7. Haier J, Nicolson GL. Models for Tumor Cell Adhesion. In: Alison M, Nicolson GL, Haier J, et al.: Cancer Handbook, Macmillan, London, 2001, 983-998 23. Gassmann P, Haier, J., Nicolson, G.L. Cell adhesion and invasion during secondary tumor formation. In: Cancer Growth and Progression, Springer Berlin Heidelberg, Volume 11, 2008, pp 21-32; DOI: 10.1007/978-1-4020-6729-7_3 8. Haier J, Nicolson GL. Models for Hematological Malignancies. In: Alison M, Nicolson GL, Haier J, et al.: Cancer Handbook, 24. Haier J, Schmidt F. In vivo animal models in tissue Macmillan, London, 2001, 1009-1024 engeneering. In: Fundamentals of tissue engeneering and regenerative medicine (Eds. U. Meyer, Th. Meyer, J. Hantschel, HP. Wiesmann) Springer Berlin Heidelberg, 2009: 773-778; DOI: 10.1007/978-3-540-77755-7_53 9. Haier J, Nicolson GL. Models for Tumor Cell-Endothelial Cell Interactions. In: Alison M, Nicolson GL, Haier J, et al.: Cancer Handbook, Macmillan, London, 2001, 1101-1114 10. Nicolson GL. Nasralla M, De Meirleir K, Haier J. Bacterial and 25. Fisch KM, Haier J. Tumor cell adhesion and invasion. The Cancer Handbook, 2nd edition, editor-in-chief: Malcolm R. viral co-infections in chronic fatigue syndrome (CFS/ME) Alison, John Wiley & Sons Ltd.,Chichester 2007; ISBN-13 978patients. Proc. Clinical & Scientific Conference on Myalgic 0-470-01852-1 Encephalopathy/Chronic Fatigue Syndrome, the Practitioners Challenge, Alison Hunter Foundation, Sydney, Australia, 2002 6 Publikationsliste Jörg Haier 26. Enns A, Haier J. Models for lymphoma. The Cancer Handbook, 2nd edition, editor-in-chief: Malcolm R. Alison, John Wiley & Sons Ltd.,Chichester 2007; ISBN-13 978-0-47001852-1 27. Krasnyanska J, Gaßmann P, Wendel C, Haier J. Zusammensetzung der extrazullulären Matrix determiniert Ausmaß und Art der Chemokin-induzierbaren Zellmotilität. Chirurgisches Forum 2007; Forumsband 36: 91-39. Hrsg. H.U.- Steinau, H.K. Schackert, H. Bauer 28. Gaßmann P, Hemping-Bovenkerk A, Küpper J, Haier J. Einfluß der sinusoidalen Architektur und der T-Zellimmunität auf metastatische Tumorzelladhäsion und –migration in vivo. Chirurgisches Forum 2007; Forumsband 36: 91-39. Hrsg. H.U.- Steinau, H.K. Schackert, H. Bauer 29. Wendel C, Haier J. Focal Adhesion Kianse. In: Schwab M (Ed.): Encyclopedia of Cancer. Springer Berlin Heidelberg, 2009, 1148-1151¸DOI: 10.1007/978-3-540-47648-1_2228 30. Haier J, Schmidt F. In vivo animal models in tissue engineering. In: Meyer U et al: Fundamentals of Tissue Engineering and Regenerative Medicine. Springer Heidelberg Berlin, 2009: 273-280, DOI: 10.1007/978-3-540-77755-7, ISBN: 978-354077754-0 31. Hummel R, Hussey DJ, Haier J. The Impact of miRNAs on Resistance to Anticancer Treatment: The Future for miRNABased Targeted Therapy? In: MicroRNA: Expression, Detection and Therapeutic Strategies. James A. Mulligan (Ed.). Nova Science Publishers, Inc., NY, USA. 2011 (A). Chapter 6, 125-140. ISBN 978-1-61122-846-5. 32. Hummel R, Maurer J, Haier J. Clinical Role of MiRNAs in Different Brain Tumors. In: Tumors of the Central Nervous System, Volume 3, Brain Tumors (Part 1). M.A. Hayat (Ed.). Springer 2011 (C), 185-192. ISBN: 9789400713987 33. Fritz M, Hussey DJ, Haier J, Hummel R. The impact of the let7 family on resistance to anticancer treatment. In: Dahiya N, MicroRNA let-7: Role in Human Diseases and Drug Discovery. Nova Science Publishers, NY, USA. January 2013, p. 75-87 (ISBN: 978-162081152-8) 34. Haier J. Anforderungen an den modernen Vertrieb – die Sichtweise von Krankenhausärzten. In: Strauß F. Inspirieren statt rabattieren. SPS-Institut Weisendorf/Nürnberg, 2013, S. 123-134 35. Haier J, Sulkowski U. Allgemeinchirurgie. In: Jahn U, van Aken HK, Zusatzweiterbildung Intensivmedizin, 2. Auflage, Thieme Stuttgart, 2013, 148-187 36. Lindner, K., Haier, J., Hummel, R. (2014) MicroRNAs and Their Clinical Impact on Resistance to Anticancer Treatment. In Babashah, S.: MicroRNAs: Key Regulators of Oncogenesis. Springer 1 (1): 369-386 7
