In preparation

Early Developmental Stages of Psychopathology (EDSP)
List of Publications
15.12. 2011
In preparation
Beesdo, K., NN, Höfler, M., Lieb, R. & Wittchen, H.U. (in prep). Persistence of anxiety and
depressive disorders and it's determinants and consequences.
Barth, A., Beesdo, K., NN, Höfler, M., Lieb, R. & Wittchen, H.U. (in prep). What characterizes supernormals? A comparative study among adolescents and young adults with or without familial and/or
own psychopathology.
Behrendt, S., Wittchen, H.-U., Perkonigg, A., Lieb, R., Beesdo, K. (in prep.). Characteristics of
substance use disorder symptoms in adolescence and early adulthood for alcohol, nicotine and
cannabis use disorders
Behrendt, S., Wittchen, H.-U., Perkonigg, A., Lieb, R., Beesdo, K. (in prep.). Subtypes of alcohol use
disorder symptomatology and dimensionality of alcohol use disorder symptoms in adolescence´and
early adulthood.
Behrendt, S., Wittchen, H.-U., Perkonigg, A., Essau, C., Lieb, R., Beesdo, K. (in prep.). Anxiety,
affective and substance use disorders in mothers and fathers play different roles in offspring risk for
alcohol, nicotine and cannabis use and disorders.
Brueckl, T., Pfister, H., Wittchen, H.-U., Holsboer, F., Ising, M., Lieb., R. & Zimmermann, P. (in
prep.) Antenatal maternal stress, genetic vulnerability and the risk of depression later in life.
Brueckl, T., Zimmermann, P., Pfister, H., Wittchen, H.-U., Holsboer, F., Ising, M. & Lieb, R. (in
prep.) Do polymorphisms in the serotonine transporter gene interact with the family environment in
predicting first onset of depression?
Brückl T, Zimmermann P, Nocon A, Wittchen HU, Ising M, Lieb R (in preparation). Exposure to natal
complications influences vulnerability for depression under traumatic conditions.
Brückl, T. M., Zimmermann, P., Nocon, A., Wittchen, H. U., Pfister, H., Ising M. & Lieb, R. (in
preparation). Youth with mental disorders grown up: a ten-year follow-up of a community sample of
adolescents. Target: Childhood section of Journal of Clinical Psychiatry
Dominguez, M.D.G.; Wichers, M.; Lieb, R.; Wittchen, H-U; Van Os, J. Understanding psychosis as a
dimensional phenotype: positive and negative symptoms dimensions in the general population.
Dominguez M.D.G; Lieb R, Wittchen H-U; van Os J. Paranoia as an independent phenotype in a
longitudinal population-based study.
Green MJ, Dominguez M, Leib R, Wittchen H-U, Linscott R, van Os J. Shared latent continua for
psychotic and affective experiences? An application of factor mixture modelling in a healthy
adolescent population. (Manuscript in preparation).
Goodwin, R.D., Beesdo, K., Zimmermann, P., Hoefler, M., Lieb, R. & Wittchen, H.-U. (in prep).
Prenatal cigarette smoking and the risk of anxiety disorders among offspring: Results from a
population-based, prospective longitudinal study.
Gloster, A., Beesdo, K., Höfler, M., Hollander, E., NN, Lieb, R. and Wittchen, H.-U. (in prep).
OCD subtypes: Effect on Incidence, course, symptom stability, and impairment in the first three
decades of life
Heck, A., Lieb, R., Zimmerman, P., Brückl, T., Pfister, H., Lucae, S., Roeske, D., Müller-Myhsok, B.,
Uhr, M., Holsboer, F. & Ising, M. (in prep.) Findings from a whole genome association study for
personality traits in two independent Caucasian samples.
-wide family-based association study.
Hollenbach, Zimmermann, Nocon, Brückl, Pfister, NN, Wittchen & Lieb (in preparation). Correlates
and risk factors for onset and stability of OCD: Results from an epidemiological community study
with a ten-years follow-up
Hollenbach, NN, Wittchen, Lieb & Zimmermann (in preparation). Comorbid disorders as predictors
and consequences of OCD in representative sample with a ten-years follow-up.
Hommes J, van Os J, Lieb R, Wittchen H-U, van Winkel R Developmental patterns of hallucinations
and delusions in a prospective epidemiological cohort.
Kuepper R, van Os J, Lieb R., Wittchen H-U & Henquet C. Does cannabis use interact with urbanicity
in causing psychosis?
Knappe, S., Beesdo, K., Lieb, R. & Wittchen, H.-U. (idea in prep). On the continuity of social phobia
state of the art and empirical outlook (homotypic or heterotypic course of social phobia)
Knappe, S., Beesdo-Baum, K., Lieb, R. & Wittchen, H.-U- (in prep). Specificity of family risk factors
for the onset and course of social phobia
Knappe, S., N.N., Beesdo-Baum, K., Lieb, R. & Wittchen, H.-U- (in prep) Externalizing disorders and
incident anxiety disorders.
Beesdo, K., Knappe, S., Fehm, L., Lieb, R., & Wittchen, H.-U. (submitted). Social Anxiety Disorder:
Natural Course and Persistence in the First Three Decades of Life. Acta Psychiatrica Scandinavica.
Lataster J, van Os J, Lieb R, Wittchen H-U, Myin-Germeys I. Psychosocial factors in the pathogenesis
of psychosis: a 10-year prospective longitudinal cohort study investigating the effects of childhood
and later life adversity on psychosis outcome.
Low N, Beesdo K, Gloster AT, Hoefler M, Lieb R, Wittchen HU. (in prep.) Longitudinal anxiety
disorder outcomes of offspring with differential parental risk: A prospective community and family
study
Low N, Beesdo K, Gloster AT, Hoefler M, Lieb R, Wittchen HU. (in prep.) The impact of parental
mood and anxiety disorders on offspring bipolar and depressive disorders
Low N, Behrendt S, Beesdo K, Hoefler M, Lieb R, Wittchen HU. (in prep.) The effect of parental
alcohol dependence on offspring age of alcohol use, and the risk and speed of transition to dependence
Low N, Gloster AT, Beesdo K, Hoefler M, Lieb R, Wittchen HU. (in prep.) The interaction between
depressive attribution and familial risk for depression
Nocon et al. (in preparation). The interplay of parental anxiety and parenting styles in the onset of
panic disorder and agoraphobia.
Nocon et al. (in preparation). Do temperamental and personality traits play a key role in the familial
aggregation of anxiety disorders?
Nocon, A., Brückl, T., Zimmermann, P., Lieb, R., Wittchen, H.-U. (in preperation)
Specific vulnerability and risk factors for the onset of panic disorder,agoraphobia and other phobias.
N.N.
Pfennig*, A., Beesdo*, K., Höfler, M., Lieb, R., Bauer, M. & Wittchen, H.-U. (in prep-b). Symptom
Characteristics of Unipolar and Bipolar Depression in the First Three Decades of Life.
Perkonigg, A., Umpf, H.-J., WIttchen, H.-U. Remission fom substance dependence without formal
help: Findings from a prospective longitudianl community study. Vorgesehen für SUCHT Sonderheft
Perkonigg, A., Behrendt, S., Goodwin, R.D., Lieb, R. & Wittchen, H.-U. (in prep). A prospective
comparison of longitudinal patterns of nicotine, alcohol and cannabis use during adolescence and
young adulthood I:. Stability and transitions
Perkonigg, A., Behrendt, S., Goodwin, R.D., Lieb, R. & Wittchen, H.-U. (in prep). A prospective
comparison of longitudinal patterns of nicotine, alcohol and cannabis use during adolescence and
young adulthood II: The impact of multiple substance use
Perkonigg, A , Stein, M.B. & Wittchen, H.-U. (in prep.). The impact of posttraumatic stress disorder
symptoms during a 10-year prospective-longitudinal observation period.
Schönfeld, S., NN, H.-U- Wittchen (in prep.). Die Rolle der kognitiven und emotionalen
Selbstregulation bei der Entstehung einer PTSD.
Schreier, A., Wittchen, U., Höfler, M., & Lieb, R. (in preparation). Patterns and temporal order of
onset of the familial aggregation of affective, anxiety and substance use disorders. Results from a
prospective community study.
van Os J, Lieb R, Wittchen H-U. Developmental patterns of hallucinations and delusions in a
prospective epidemiological cohort.
van Os et al. (in preparation). Sex differences in psychosis persistence in the general population. N.N.
van Os et al. (in prep.) The course of psychosis over time and predictors thereof.
van Os et al. (in preparation). The incidence of bipolar illness in a population cohort. N.N.
van Os et al. (in preparation). Predictors of transition from subclinical mania to bipolar disorder. N.N.
van Os et al. (in preparation). Persistence of subclinical psychosis predicts transition to clinical
disorder: validation of the psychosis proneness-psychosis persistence model. N.N.
van Os et al. (in preparation). Sex differences in psychosis persistence in the general population. N.N.
van Os et al. (in prep.) Hearing impairment and psychosis. N.N.
van Os et al. (in prep.) Cannabis, urbanicity, trauma and psychosis
van Os et al. (in prep.) Relationship hallucinations and delusions
van Os et al. (in prep.) Positive symptoms and negative symptoms of psychosis
van Os et al. (in prep.) Psychosis with and without affective disturbance
van Os et al. (in prep.) The course of psychosis over time and predictors thereof.
van Rossum I, Dominguez M.D.G., Lieb R, Wittchen HU, Van Os J. Psychosis with and without
affective disturbance.
Zimmermann, P et al. (in preparation). Stress-related personality traits as vulnerability markers for the
first onset of depression and their interplay with familial depression liability and adverse life events.
Zimmermann, P et al.(in preparation). Familial depression liability and cumulative influences of life
events over time on the onset of anxiety and depressive disorders. Does the age at exposure matter?
Zimmermann, P., Brückl, T., Pfister, H., Bronisch, T., Wittchen, H.-U., Holsboer, F., Ising, M. &
Lieb, R. (in prep.). Power based association analysis (PBAT) of BDNF, serotonergic, noradrenergic,
and dopaminergic variants in individuals with suicidal behavior.
Zimmermann, P., Brückl, T., Pfister, H., Wittchen, H.-U., Holsboer, F., Ising, M. & Lieb, R. (in prep.).
Genome-wide scan in a family-based sample of genetic variants for early onset depression.
Zimmermann, P., Brückl, T., Pfister, Heck, A., H., Wittchen, H.-U., Holsboer, F., Ising, M. & Lieb, R.
(in prep). Investigation of the interplay between genetic variants and traumatic events for the
prediction of depressive symptoms in a genome.
Zimmermann, P., Kloiber, S., Brückl, T., Pfister, H., Wittchen, H.-U., Holsboer, F., Ising, M. & Lieb,
R. (in prep). Evidence that the relationship of variations in the leptin receptor (LEPR) gene and
depressive symptoms is moderated by severe trauma.
Petra Zimmermann, Jules Angst, Hildegard Pfister, Agnes Nocon, Hans-Ulrich Wittchen, Roselind
Lieb & Tanja Brückl (in prep.): Heterogeneity of DSM-IV Major Depressive Disorder as a
consequence of hidden bipolarity: Findings from a prospective-longitudinal community study
Petra Zimmermann, Jules Ammunity study
Hollenbach, Nocon, Brückl, Pfister, NN, Wittchen, Lieb & Zimmermann (in preparation). Prevalence,
course, and characteristics of OCD in the first three decades of life
Submitted
Beesdo-Baum, K., Knappe, S., Fehm, L., Lieb, R. & Wittchen, H.-U. (submitted). The natural course
of Social Anxiety Disorder among adolescents and young adults. Acta Psychiatrica Scandinavica.
Brückl, T.M., Zimmermann, P., Schreier, A., Höfler, M., Wittchen, H.-U. & Lieb, R. (submitted). The
interplay of maternal psychopathology and separation anxiety for the development of subsequent
mental disorders. Journal of Child Psychology and Psychiatry.
Brückl., T.M., Zimmermann, P., Wittchen, H.-U. & Lieb, R. (submitted). Separation anxiety predicts
mental disorders in females but not in males: Effects on onset, persistence and comorbidity. Acta
Psychiatrica Scandinavica.
Dominguez, Maria de Gracia; Wichers, Marieke; Lieb, Roselind; Wittchen, Hans-Uli; Van Os, Jim.
(submitted). Evidence that onset of clinical psychosis is the outcome of progressively more persistent
subclinical psychotic experiences: an 8-year cohort study. Schizophrenia Bulletin.
Dominguez, Maria de Gracia; Can Saka, Meram; Lieb, Roselind; Wittchen, Hans-Uli; Van Os, Jim.
Onset of Psychotic Illness: Negative Symptoms Increasing Risk for Positive Symptoms Increasing
Risk for Impairment? A 10-year Cohort Study. American Journal of Psychiatry. In prep.
Knappe, S., , Beesdo-Baum, K., Fehm, L., Lieb, R. & Wittchen, H.-U. Characterizing the association
between unfavourable parental rearing and offspring social phobia, its predictors and specificity.
Social Psychiatry and Psychiatric Epidemiology
Kuepper R.., van Os J., Lieb R., Wittchen H.-U., Hoefler M., & Henquet C. Continued cannabis use
and risk of incidence and persistence of psychotic symptoms: A 10-year follow-up cohort study.
Submitted to British Medical Journal, first revision.
Kuepper R.., van Os J., Lieb R., Wittchen H.-U., & Henquet C. Do cannabis and urbanicity coparticipate in causing psychosis? Evidence from a 10-year follow-up cohort study. Submitted to
Psychological Medicine.
Lataster J, Myin-Germeys I, Lieb R, Wittchen H-U, van Os J (under review) Adversity and psychosis:
a 10-year prospective study investigating synergism between early and recent adversity in psychosis.
Schiz Res.
Lieb, R., Schwender, L., Nocon, A., Hollenbach, N., Angst, J., Pfister, H., & Wittchen, H.-U.
(submitted). Obsessive compulsive disorder among adolescents and young adults. Results from the
prospective-longitudinal EDSP-Study. American Journal of Psychiatr.,
NC Low, S Behrendt, K Beesdo, AT Gloster, M Höfler, R Lieb, HU Wittchen. (submitted).The role of
parental alcohol dependence on offspring alcohol use and transition to dependence: a prospective
community and family study. Abstract. Canadian Academy of Psychiatric Epidemiology Sept 8, 2008,
Vancouver, Canada.
Schutters, S. I. J., Dominguez, M. d. G., Lieb, R., Knappe, S., Wittchen , H.-U., v. Os, J., et al.
(submitted). Comorbid social phobia and paranoia: Valid association or delusion? Acta Psychiatrica
Scandinavica.
Schutters, SIJ, Dominguez, M, Knappe S, Lieb R, van Os J, Schruers KR, Wittchen HU (submitted).
Comorbid Social Phobia and Paranoid symptoms: Valid Association or Delusion? Acta Psychiatrica
Scandinavia
Van der Werf, Margriet; Thewissen, Viviane; Dominguez, Maria de Gracia; Lieb, Roselind; Wittchen,
Hans-Uli; Van Os, Jim. Adolescent Development of Social Reasoning Skills and Psychosis: A 10-year
Longitudinal Study of Hearing Impairment. Psychological Medicine.
Wigman, J.T.W., van Nierop, M., Vollebergh, W.A.M., Lieb, R., Beesdo-Baum, K., Wittchen, H.-U.,
van Os, J. (submitted). How Psychotic is non-psychotic disorder? Evidence that psychotic
symptoms are prevalent in disorders of anxiety and depression, impacting on illness onset, risk and
severity. Schizophrenia Bulletin.
In press
Behrendt, S., Beesdo-Baum, K., Höfler, M., Perkonigg, A., Bühringer, G., Lieb, R., Wittchen, H.-U.
(in press). The relevance of age at first alcohol and nicotine use for initiation of cannabis use and
progression to cannabis use disorders. Drug and Alcohol Dependence.
Bronisch, T., Pfister, H., Wittchen, H.-U., & Lieb, R. (in press). Recall of previously reported suicide
attempts after four years in a community sample of adolescents and young adults. Psychological
Medicine.
Grabitz M, Behrendt S, Klotsche J, Bühringer G, Lieb R & Wittchen H-U (in Press). Drinking
Patterns, Impairment, and Stability in Community Youth with Diagnostic Orphan Status of Alcohol
Dependence. Addictive Behaviours.
Van der Werf, Margriet; Thewissen, Viviane; Dominguez, Maria de Gracia; Lieb, Roselind; Wittchen,
Hans-Uli; Van Os, Jim. Adolescent Development of Psychosis as an outcome of Hearing Impairment:
A 10-year Longitudinal study. Psychological Medicine, in press
2011
Beesdo-Baum K, Winkel S, Pine DS, Hoyer J, Höfler M, Lieb R, Wittchen H-U. (2001) The
diagnostic threshold of generalized anxiety disorder in the community: A developmental perspective.
Journal of Psychiatric Research 2011 in press, e-pub ahead of print;
doi:10.1016/j.jpsychires.2010.12.007.
Behrendt, S., Beesdo-Baum, K., Zimmermann, P., Höfler, M., Perkonigg, A., Bühringer, G., Lieb, R.,
Wittchen, H.U., 2010. The role of mental disorders in the risk and speed of transition to alcohol use
disorders among community youth. Psychol Med. 41, 1073–1085.
Knappe, S., Beesdo, K., Fehm, L., Stein, M. B., Lieb, R., & Wittchen, H. U. (2011). Social fear and
social phobia types among community youth: Differential clinical features and vulnerability factors.
Journal of Psychiatric Research, 45, 111-120.
Kuzenko, N., Sareen, J., Beesdo-Baum, K., Perkonigg, A., Höfler, M., Simm, J., Lieb, R., & Wittchen,
H.-U. (2011). Associations between use of cocaine, amphetamines or psychedelics and psychotic
symptoms in a community sample. Acta Psychiatrica Scandinavica, 123(6), 466-474.
Schutters, S. I. J., Dominguez, M.-d.-G. , Knappe, S., Lieb, R., van Os, J., Schruers, K. R. J.,
Wittchen, H.-U. (2011).The association between social phobia, social anxiety cognitions and paranoid
symptoms. ACTA PSYCHIATRICA SCANDINAVICA. 1-15.
Smeets, Feikje; Lataster, Tineke; Dominguez, Maria-de-Gracia; Hommes, Juliette; Lieb, Roselind;
Wittchen Hans-Ullrich; van Os, Jim (2011, abstract). Evidence that onset of psychosis in the
population reflects early hallucinatory experiences that through environmental risks and affective
dysregulation become complicated by delusions. Schizophrenia Bull. 37: 63-63.
2010
Beesdo, K., Pine, D.S., Lieb, R. & Wittchen, H.U. (2010). Incidence and Risk Patterns of Anxiety and
Depressive Disorders and Categorization of Generalized Anxiety Disorder. Archives of General
Psychiatry. 67 (1). 47-57.
Behrendt, S., Böhm, I. , Wittchen , H-U., Bühringer, G., Rehm, J., Höfler, M., Lieb, R., Beesdo-Baum,
K. (2010). Alkoholstörungssymptome bei Jugendlichen und jungen Erwachsenen in der
Allgemeinbevölkerung: Eine prospektiv-longitudinale Studie. Abstract. In: Zeitschrift für Klinische
Psychologie und Psychotherapie. 39 (1). Supplementum 1/10. S.4.
Behrendt, S., Böhm, I. , Wittchen , H-U., Bühringer, G., Rehm, J., Höfler, M., Lieb, R., Beesdo-Baum,
K. (2010). Alcohol use disorder symptoms in adolescence and early adulthood: a prospectivelongitudinal community study. Abstract. In: Alcoholism: Clinical and Experimental Research.
Supplement to 34 (6). p179a.
Dominguez, Maria de Gracia; Can Saka, Meram; Lieb, Roselind; Wittchen, Hans-Uli; Van Os, Jim.
Early Expression of Negative/Disorganized Symptoms Predicts Psychotic Experiences and
Subsequent Clinical Psychosis; A 10-Year Study. American Journal Psychiatry, 2010; 167:1075-1082
Knappe S, Beesdo, K., Hans-Ulrich Wittchen (2010): Familial Factors in Social Anxiety Disorder:
Towards a more comprehensive approach for targeted prevention and early intervention. European
Journal of Adolescent and Child Psychiatry., 19, 857-871
Knappe, S., Beesdo, K. & Wittchen, H.-U. (2010). Familial risk factors in social anxiety disorder:
Calling for a family-oriented approach for targeted prevention and early intervention. European Child
& Adolescent Psychiatry, 19(12), 857-871.
Kuepper R., van Os J., Myin-Germeys I., Lieb R., Wittchen H.-U., & Henquet C. (2010). Cannabis as
cause of psychosis: Effects on incidence and persistence of psychotic symptoms. Schizophrenia
Research, 117(2-3), 298 (abstract of poster).
Kuepper R.., van Os J., Lieb R., Wittchen H.-U., Hoefler M., & Henquet C (2011). Continued cannabis use
and risk of incidence and persistence of psychotic symptoms: A 10-year follow-up cohort study. British
Medical Journal, 342, d738.
Kuepper R.., van Os J., Lieb R., Wittchen H.-U., & Henquet C. (2011). Do cannabis and urbanicity coparticipate in causing psychosis? Evidence from a 10-year follow-up cohort study. Psychological Medicine,
Apr 5, 1-9 [Epub ahead of print].
Martini, J., Knappe, S., Beesdo-Baum, K., Lieb, R. & Wittchen, H.-U. (2010). Anxiety disorders
before birth and self-perceived distress during pregnancy: Associations with maternal depression and
obstetric, neonatal and early childhood outcomes. Early Human Development, 86(5), 305-310.
Smeets, F., Lataster, T., Dominguez, M.D.G., Hommes, J., Lieb, R., Wittchen, H.U., van Os, J.
(2010). Evidence that the onset of psychosis in the population reflects early hallucinatory experiences
that through environmental risks and affective dysregulation become complicated by delusions.
Schizophrenia Bulletin, doi:10.1093/schbul/sbq117
Tijssen MJA, Van Os J, Wittchen HU, et al. (2010). Risk factors predicting onset and persistence of
subthreshold expression of bipolar psychopathology among youth from the community
ACTA PSYCHIATRICA SCANDINAVICA, 122 (3). p 255-266.
Tijssen, M.J.A., Van Os, J., Wittchen, H.-U., Lieb, R., Beesdo, K., Mengelers, R., Wichers, M. (in
press) Prediction of transition from common adolescent bipolar experiences to bipolar disorder. British
Journal of Psychiatry Br J Psychiatry. 2010 Feb;196(2):102-8
Tijssen, M.J.A., van Os, J., Wittchen, H.-U., Lieb, R., Beesdo, K., Wichers, M. Risk factors
predicting onset and persistence of subthreshold expression of bipolar psychopathology among youth
from the community. Acta Psychiatrica Scand, 2010 Sep;122(3):255-66
Tijssen MJA, Van Os J, Wittchen HU, et al. (2010). Evidence that bipolar disorder is the poor
outcome fraction of a common developmental phenotype: an 8-year cohort study in young people
PSYCHOLOGICAL MEDICINE, 40 (2), p289-299.
van der Werf M, Thewissen V, Dominguez MDG, Lieb R, Wittchen H, van Os J. Adolescent
development of psychosis as an outcome of hearing impairment: a 10-year longitudinal study.
Psychological Medicine 2010:1-9.
2009
Van Rossum, Inge; Dominguez, Maria de Gracia; Lieb, Roselind; Wittchen, Hans-Uli; Van Os, Jim
(2009). Affective Dysregulation and Reality Distortion: A 10-Year Prospective Study of their
Association and Clinical Relevance. Schizophrenia Bulletin, doi:10.1093/schbul/sbp101
Beesdo-Baum, K., Höfler, M., Gloster, A.T., Klotsche, J., Lieb, R., Beauducel, A., Bühner, M.,
Kessler, R.C. & Wittchen, H.-U. (2009). The structure of common mental disorders: A replication
study in a community sample of adolescents and young adults. International Journal of Methods in
Psychiatric Research, 18(4), 204-220.
Beesdo, K., Knappe, S., Höfler, M., Lieb, R. & Wittchen, H.-U. (2009). Stability and persistence of
anxiety disorders among youth: A prospective-longitudinal community study. (Abstract). European
Neuropsychopharmacology, 19(Suppl. 3), S590.
Beesdo, K., Höfler, M., Leibenluft, E., Lieb, R., Bauer, M., & Pfennig, A. (2009). Mood episodes and
mood disorders: Patterns of incidence and conversion in the first three decades of life. Bipolar
Disorders, 11, 637–649.
Behrendt, S., Wittchen, H.-U., Höfler, M., Lieb, R., Beesdo, K., 2009. Transitions from First
Substance Use to Substance Use Disorders in Adolescence: Is Early Onset associated with a Rapid
Escalation? Drug and Alcohol Dependence. 99, 68-78
Dominguez, Maria de Gracia; Wichers, Marieke; Lieb, Roselind; Wittchen, Hans-Uli; Van Os, Jim.
Evidence that Onset of Clinical Psychosis is the Outcome of Progressively more Persistent Subclinical
Psychotic Experiences: an 8-year Cohort Study. Schizophrenia Bulletin doi:10.1093/schbul/sbp022 ,
2009.
Henquet C., Kuepper R., Konings M., Lieb R., Wittchen H.-U., & van Os J. (2009). Do cannabis and
urbanicity interact in causing psychosis? Schizophrenia Bulletin, 35(supplement 1), 87. (abstract from
oral presentation).
Knappe, S., Beesdo, K., Fehm, L., Höfler, M., Lieb, R., & Wittchen, H.-U. (2009). Do Parental
Psychopathology and Unfavorable Family Environment Predict the Persistence of Social Phobia?
Journal of Anxiety Disorders. 23, 986–994
Knappe, S., Beesdo, K., Fehm, L., Lieb, R., Wittchen, H.-U. (2009). Die Bedeutung familiärer
Risikofaktoren für den Beginn und Verlauf Sozialer Phobien: Ergebnisse einer repräsentativen
Bevölkerungsstudie. Abstract. Zeitschrift für Klinische Psychologie und Psychotherapie.
Knappe, S., Beesdo, K., Fehm, L., Lieb, R. & Wittchen, H.-U. (2009). Associations of familial risk
factors with social fears and social phobia: Evidence for the continuum hypothesis in social anxiety
disorder? Journal of Neural Transmission, 116(6): p. 639–648.
Knappe, S., Lieb, R ., Beesdo, K., Fehm, L., Low, N.C.P., Gloster, A. T. & Wittchen, H.-U. (2009)
The Role of Parental Psychopathology and Family Environment for Social Anxiety Disorder in the
First Three Decades of Life. Depression and Anxiety, 26(4): p. 363-370.
Kuepper R., van Os J., Lieb R, Wittchen H.-U., & Henquet C. (2009). Cannabis use and true incidence
of psychotic sypmtoms in a population-based sample. Schizophrenia Bulletin, 35(supplement 1), 88
(abstract from poster)
Perkonigg, A., Owashi, T., Stein, M.B., Wittchen, H.-U. (2009) Posttraumatic stress disorder and
obesity. Evidence for a risk association. American Journal of Preventive Medicine. 36, 1-8.
Tijssen, M., Van Os, J., Wittchen, H.-U., Lieb, R., Mengelers, R., Krabbendam, L., Wichers, M.,
2009. Evidence that bipolar disorder is the poor outcome fraction of a common developmental
phenotype: an 8-year cohort study in young people. Psychological Medicine. 11, 1-11.
van Os J, Linscott RJ, Myin-Germeys I, et al.: A systematic review and meta-analysis of the psychosis
continuum: evidence for a psychosis proneness-persistence-impairment model of psychotic disorder.
Psychol Med 39:179-195, 2009.
Van Rossum, Inge; Dominguez, Maria de Gracia; Lieb, Roselind; Wittchen, Hans-Uli; Van Os, Jim
(2009). Affective Dysregulation and Reality Distortion: A 10-year Prospective Study of their
Association and Clinical Relevance. Schizophrenia Bulletin, doi:10.1093/schbul/sbp101, 2009.
Wittchen, H.-U., Behrendt, S., (shared first authorship) Perkonigg, A., Lieb, R., Beesdo, K. (2009). A
typology of cannabis-related problems among individuals with repeated illegal drug use in the first
three decades of life: Evidence for heterogeneity and different treatment needs. Drug and Alcohol
Dependence. 102. 151–157.
Wittchen, H.-U., Beesdo, K., Gloster, A.T., Höfler, M., Klotzsche, J., Lieb, R. Beauducel, A., Bühner,
M. Kessler, R. (2009; e-pub ahead of print). The structure of mental disorders re-examined: Is it
developmentally stable and robust against additions? International Journal of Methods in Psychiatric
Research. DOI: 10.1002/mpr.298
2008
Beesdo, K. & Wittchen, H.-U. (2008). The prevalence, course and burden of anxiety disorders.
Abstract. European Neuropsychopharmacology. 18 (4). 173-174.
BEHRENDT, S., WITTCHEN, H.-U., HÖFLER, M. et al. Risk and speed of transitions to first
alcohol dependence symptoms in adolescents: a 10-years longitudinal community study in Germany.
Addiction 2008; 103: 1638-1647.
Behrendt, S., H-U Wittchen, M Höfler, R Lieb, K Beesdo (2008). Early smoking onset and other
substance use: The risk and speed of transition to regular nicotine use and dependence. Abstract.
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S Behrendt, H-U Wittchen, M Höfler, R Lieb, NCP Low, J Rehm, K Beesdo (2008).
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Knappe, S., Lieb, R. Beesdo, K., Fehm, L., Low, N.C. P., GLoster, A. T. & Wittchen, H.-U. (2008).
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2008. Differential Familial Liability of Panic Disorder and Agoraphobia. Depression and Anxiety. 25,
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Rohrbacher, H., Hoyer, J., Beesdo, K., Höfler, M., Bittner, A., Lieb, R., Wittchen, H.-U. (2008).
Psychometric properties of the Retrospective Self Report of Inhibition (RSRI) in a representative
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Wittchen, H.-U., Behrendt, S. (shared first authorship), Höfler, M., Perkonigg, A., Lieb, R.,
Bühringer, G., Beesdo, K. (2008). What are the High Risk Periods for Incident Substance Use and
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prospective-longitudinal investigation in the community. Abstract. European
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Zimmermann, P., Brückl, T., Lieb, R., Nocon, A., Ising, M., Beesdo, K. & Wittchen, H.U. (2008). The
interplay of familial depression liability and adverse events in predicting the first onset of depression
during a 10-year follow-up. Biological Psychiatry, 63, 406-414.
Zimmermann, P., Kloiber, S., Brueckl, T., Pfister, H., Wittchen, H.-U., Ising, M., Lieb, R. (2008).
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2007
Brückl, T.M., Wittchen, H.-U., Höfler, M., Pfister, H., Schneider, S., Lieb, R. (2007).
Childhood Separation Anxiety and the Risk of Subsequent Psychopathology: Results from a
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Cougnard, A., Marcelis, M., Myin-Germeys, I., De Graaf, R., Vollebergh, W., Krabbendam, L., Lieb,
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expression of psychosis combine with environmental risk to cause persistence of psychosis? A
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Lieb, Höfler, Wittchen, Bronisch. (2007). Smoking predicts suicidality: findings from a prospective
community study. Abstract. EUROPEAN PSYCHIATRY. 22 (Suppl. 1). 40-40.
Gloster, A., Beesdo, K., Höfler, M., Lieb, R. & Wittchen, H.-U. (2007). Anxiety disorders and the risk
for subsequent mood and psychotic disorders in the first three decades of life (Abstract).
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Beesdo, K., Bittner, A., Pine, D.S., Stein, M.B., Höfler, M., Lieb, R. & Wittchen, H.-U. (2007). Social
anxiety disorder: patterns of incidence and secondary depression risk (Abstract). European
Neuropsychopharmacology, 17(Suppl. 4), S511-S512.
Nocon, A. (2007). Angst und Depression bei Jugendlichen. Häufigkeit, Komorbiditätsmuster und
zeitlicher Verlauf. Saarbrücken: VDM Verlag Dr. Müller.
Nocon A, Wittchen H-U, Beesdo K, Brückl T, Hofler M, Pfister H, Zimmermann P, Lieb R (2007).
Differential Familial Liability of Panic Disorder and Agoraphobia. Depression and Anxiety.
Ströhle, A., Höfler, M., Wittchen, H.-U., Pfister, H. & Lieb, R. (2007). Physical activity and
prevalence and incidence of mental disorders in adolescents and young adults. /Psychological
Medicine. 37: 1657-1666.
Beesdo, K., Bittner, A., Pine, D.S., Stein, M.B., Höfler, M., Lieb, R. & Wittchen, H.-U. (2007).
Incidence of Social Anxiety Disorder and the consistent risk for secondary depression in the first three
decades of life. Archives of General Psychiatry.64(8): 903-912.
Höfler, M., T. Brückl, A. Bittner and R. Lieb (2007). "Visualizing multivariate dependencies with
Association Chain Graphs." Methodology 3(1): 24- 34.
Höfler, M., R. Lieb and H.-U. Wittchen (2007). "Estimating causal effects from observational data
witha a model for multiple bias." International Journal of Methods in Psychiatric Research 16(2): 7787.
Nocon, A., Wittchen, H.-U., Beesdo, K., Brückl, T., Hofler, M., Pfister, H., Zimmermann, P., Lieb, R.,
Ising, M. (2007, Juli). Differential familial liability of panic disorder and agoraphobia. Max-PlanckInstituts für Psychiatrie - Institutssymposium. 24. bis 25. Juli 2007 in München. München: MaxPlanck-Institut. Abstract.
Wittchen, H.-U., Fröhlich, C., Behrendt, S., Günther, A., Rehm, J., Zimmermann, P., Lieb, R.,
Perkonigg, A. (2007). Cannabis use and cannabis use disorders and their relationship to mental
disorders : A 10-years prospective-longitudinal community study in adolescents. Drug and Alcohol
Dependence. 88, Suppl. 1, 60-70.
Runge, A.J., Beesdo, K. Lieb, R., Wittchen, H-U. (2007). Wie häufig nehmen Jugendliche und junge
Erwachsene mit Angststörungen eine psychotherapeutische Behandlung in Anspruch? Abstract.
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2006
Beesdo, K., Wittchen, H.U., Höfler, M., Lieb, R. & Pfister, H. (2006). Risk factors for generalized
anxiety: a prospective-longitudinal epidemiological study of adolescents and young adults. Abstract.
European Neuropsychopharmacology, 16(suppl. 4), s453.
Beesdo, K., Wittchen, H.U., Guenther, A. & Lieb, R. (2006). Association and temporal relation of
generalized anxiety and pain in the first three decades of life: a 10-year follow-up study among
adolescents and young adult. Abstract. European Neuropsychopharmacology, 16(suppl. 4), s455.
Beesdo, K., Höfler, M. & Wittchen, H.U. (2006). Is Generalized Anxiety Disorder an internalizing
distress disorder? Abstract. Neuropsychopharmacology, 31(suppl.1), S169.
Beesdo, K., Meißner, N., Fehm, L., Wittchen, H.-U. & Lieb, R. (2006). Wie stabil sind Soziale
Phobien über zehn Jahre hinweg? Ergebnisse einer prospektiven Follow-up-Studie. (How stabile are
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Henquet C , Krabbendam L, Spauwen J , Kaplan C , Lieb R , Wittchen HU , Van Os J. Prospective
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Krebs, A. Mühlberger, P. Weyers & P. Pauli (Eds.), Wissenschaftliche Beiträge zum 24. Symposium
der Fachgruppe Klinische Psychologie und Psychotherapie der Deutschen Gesellschaft für
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Lieb, R., Bronisch, T., Höfler, M., Schreier, A. & Wittchen, H.-U. (2006). Suizidalität von Müttern
und Risiko von Suizidalität der Kinder: Ergebnisse einer epidemiologischen Studie. Suizidprophylaxe.
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zum 24. Symposium der Fachgruppe Klinische Psychologie und Psychotherapie der Deutschen
Gesellschaft für Psychologie (DGPs). 25. bis 27. Mai 2006 in Würzburg. Lengerich: Pabst Science
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Bronisch, T., L. Schwender, M. Höfler, H.-U. Wittchen and R. Lieb (2006). "Mania, hypomania, and
suicidality: findings from a prospective community study. Abstract." European
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Christl, B., H.-U. Wittchen, H. Pfister, R. Lieb and T. Bronisch (2006). "The Accuracy of Prevalence
Estimations for Suicide Attempts. How Reliably Do Adolescents and Young Adults Report Their
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Günther, A. and M. Höfler (2006). "Different results on tetrachorical correlations in Mplus and Stata –
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Lieb, R., T. Bronisch, M. Höfler, A. Schreier and H.-U. Wittchen (2006). "Maternal suicidality and
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Neuropsychopharmacology 16(Suppl. 4): 295-296.
Perkonigg, A., A. Settele, H. Pfister, M. Höfler, C. Fröhlich, P. Zimmermann, R. Lieb and H.-U.
Wittchen (2006). "Where have they been? Lifetime service use of regular substance users with and
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Spauwen, J., Krabbendam, L., Lieb, R., Wittchen, H. U., & van Os, J. (2006). Evidence that the
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Spauwen, J., Krabbendam, L., Lieb, R., Wittchen, H. U., & van Os, J. (2006). Impact of psychological
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Wittchen, H.-U., J. Spauwen, L. Krabbendam, R. Lieb and J. Van Os (2006). "Evidence that the
outcome of developmental expression of psychosis is worse for adolescents growing up in an urban
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Effect of ethanol on hypothalamic-pituitary-adrenal system response to psychosocial stress in sons of
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Zimmermann, U., Spring, K., Wittchen, H.-U. & Holsboer, F. (2004). Effects of ethanol
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Zimmermann, U., Spring, K., Wittchen, H.-U., Himmerich, H., Landgraf, R., Uhr, M. & Holsboer, F.
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Zimmermann, U., Uhr, M., Spring, K., Wittchen, H.-U. & Holsboer, F. (2004). Stress-induced
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Spauwen, J., Krabbendam, L., Lieb, R., Wittchen, H.-U. & van Os, J. (2004). Early maternal stress
and health behaviours and offspring expression of psychosis in adolescence. Acta Psychiatrica
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Höfler, M., Lieb, R., Hoyer, J., Friis, R. H. & Wittchen, H.-U. (2004). Correction to the paper "How
association chain graphs can model pathways into disease. International Journal of Methods in
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Henquet C, Krabbendam L, Spauwen J, Lieb R, Wittchen HU, van Os J. (2004). Cannabis use and
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Beesdo, K., Wittchen, H.-U., Höfler, M., Pfister, H., Bittner, A. & Lieb, R. (2004). Is generalized
anxiety disorder a chronic disorder? Predicting chronicity and spontaneous remission. Abstract.
European Neuropsychopharmacology, 14 (Suppl. 3), 310.
Bittner, A., Goodwin, R. D., Wittchen, H.-U., Beesdo, K., Höfler, M. & Lieb, R. (2004). What
characteristics of primary anxiety disorders predict subsequent major depression? Journal of Clinical
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Bittner, A., Wittchen, H.-U., Beesdo, K., Höfler, M. & Lieb, R. (2004). Behavioural inhibition in
childhood and the development of anxiety disorders and depression in adolescence and young
adulthood. Abstract. Acta Psychiatrica Scandinavica. Supplementum, 110 (421), 9-10.
Goodwin, R. D., Lieb, R., Höfler, M., Pfister, H., Bittner, A., Beesdo, K. & Wittchen, H.-U. (2004).
Panic attack as a risk factor for severe psychopathology. American Journal of Psychiatry, 161 (12),
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Lieb, R., Bronisch, T., Höfler, M., Schreier, A. & Wittchen, H.-U. (2004). Suicidality runs in families:
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Perkonigg, A., Wittchen, H.-U., Zimmermann, P., Nocon, A., Settele, A., Spiegel, B., Bühringer, G. &
Lieb, R. (2004). Grundlagen und Forschungsstrategien regionaler Bedarfs- und Allokationsforschung
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Perkonigg, A., Yonkers, K. A., Pfister, H., Lieb, R. & Wittchen, H.-U. (2004). Risk factors for
Premenstrual Dysphoric Disorder in a community sample of young women - the role of traumatic
events and Posttraumatic Stress Disorder. Journal of Clinical Psychiatry, 65 (10), 1314-1322.
van Os, J., Spauwen, J., Lieb, R., Wittchen, H.-U. & Krabbendam, L. (2004). Do big cities turn on
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van Os, J., Spauwen, J., Lieb, R., Wittchen, H.-U. & Krabbendam, L. (2004). Adolescents with a PreExisting Vulnerability for Psychosis are More Likely to Develop Symptoms if They Grow Up in an
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Wittchen, H.-U., Bittner, A. & Lieb, R. (2004). Vulnerability, risk factors, course and outcome of
specific anxiety disorders: Evidence for dimensional perspectives? Abstract. European
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Wittchen, H.-U., Brückl, T. & Ruhl, U. (2004). Haben frühe psychische Störungen Folgen? In
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community study of adolescents and young adults." European Addiction Research.
Isensee, B., Wittchen, H.-U., Stein, M. B., Höfler, M. & Lieb, R. (2003). Smoking increases the risk of
panic. Findings from a prospective community study. Archives of General Psychiatry, 60 (7), 692-700.
Kessler, R. C., Aguilar-Gaxiola, S., Andrade, L., Bijl, R., Borges, G., Caraveo-Anduaga, J. J., DeWit,
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(2003). Cross-national comparisons of comorbidities between substance use disorders and mental
disorders: Results from the International Consortium in Psychiatric Epidemiology. In W. J. Bukoski &
Z. Sloboda (Eds.), Handbook for drug abuse prevention theory, science, and practice. New York:
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Wittchen, H.-U., Pfister, H., Zimmermann, P. & Lieb, R. (2003). Anleitung zum Public Use File
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Wittchen, H.-U., Perkonigg, A. & Pfister, H. (2003). Trauma and PTSD - an overlooked pathogenic
pathway for premenstrual dysphoric disorder? Archives of Women's Mental Health, 6(4), 293-297.
Spauwen, J., Krabbendam, L., Lieb, R., Wittchen, H.-U. & van Os, J. (2003). Sex differences in
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Lieb, R., Schreier, A., Pfister, H. & Wittchen, H.-U. (2003). Maternal smoking and smoking in
adolscents offspring: A prospective community study of adolescents and their mothers. European
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Höfler, M., Wittchen, H.-U., Lieb, R., Hoyer, J. & Friis, R.H. (2003). Association chain graphs:
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Pezawas, L., Wittchen, H.-U., Pfister, H., Angst, J., Lieb, R., & Kasper, S. (2003). Recurrent Brief
Depressive Disorder reinvestigated: A Community Sample of Adolescents and Young Adults.
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Zimmermann, P., Wittchen, H.-U., Höfler, M., Pfister, H., Kessler, R.C. & Lieb, R. (2003). Primary
anxiety disorders and the development of subsequent alcohol use disorder: a 4-year community study
of adolescents and young adults. Psychological Medicine, 33(7), 1211-1222.
2002
Lieb, R. Schütz, C. G., Pfister, H., Sydow, K. von, & Wittchen, H.-U. (2002). Mental disorders in
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Lieb, R., Zimmermann, P., Friis, R. H., Höfler, M., & Wittchen, H.-U. (2002). The natural course of
DSM-IV somatoform disorders and syndromes among adolescents and young adults: A prospectivelongitudinal community study. European Psychiatry, 17(6), 321-331.
Wittchen, H.-U., Lieb, R., & Bittner, A. (2002). The similarities and differences of vulnerability and
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Wittchen, H.-U., Lieb, R., & Ruhl, U. (2002). Parental major depression and prospective longitudinal
risks for psychopathology from adolescence to young adulthood in their children: a community study.
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Lieb, R., Merikangas, K. R., Höfler, M., Pfister, H., Isensee, B., & Wittchen, H.-U. (2002). Parental
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Friis, R. H., Wittchen, H.-U., Pfister, H., & Lieb, R. (2002). Life events and changes in the course of
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Friis, R. H., Wittchen, H.-U., Pfister, H., & Lieb, R. (2002). Life events and changes in the course of
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Lieb, R., Isensee, B., Höfler, M., & Wittchen, H.-U. (2002). Parental depression and depression in
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Stein, M. B., Höfler, M., Perkonigg, A., Lieb, R., Pfister, H., Maercker, A., & Wittchen, H.-U. (2002).
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von Sydow, K., Lieb, R., Pfister, H., Höfler, M., & Wittchen, H.-U. (2002). What predicts incident use
of cannabis and progression to abuse or dependence? A 4-year prospective examination of risk factors
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Wittchen, H.-U., Becker, E., Lieb, R., & Krause, P. (2002). Prevalence, incidence and stability of
premenstrual dysphoric disorder in the community. Psychological Medicine, 32(1), 119-132.
2001
von Sydow, K., Lieb, R., & Wittchen, H.-U. (2001). Cannabis - eine Alltagsdroge? Epidemiologische
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von Sydow, K., Lieb, R., Pfister, H., Höfler, M., Sonntag, H., & Wittchen, H.-U. (2001). The natural
course of cannabis use, abuse and dependence over four years: A longitudinal community study of
adolescents and young adults. Drug and Alcohol Dependence, 64(3), 347-361.
Wunderlich, U., Bronisch, T., Wittchen, H.-U., & Carter, R. M. (2001). Gender differences in
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& Üstün, T. B. (2001). Mental-substance comorbidities in the ICPE surveys (english). Psychiatria
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Bronisch, T., Wunderlich, U., & Wittchen, H.-U. (2001). Geschlechtsunterschiede bei Jugendlichen
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Lieb, R., Isensee, B., Höfler, M., Pfister, H., & Wittchen, H.-U. (2001). Elterliche Alkoholbelastung
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Stein, M. B., Fuetsch, M., Müller, N., Höfler, M., Lieb, R., & Wittchen, H.-U. (2001). Social anxiety
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Wittchen, H.-U., Lieb, R., Pfister, H., & Schuster, P. (2000). The waxing and waning of mental
disorders: Evaluating the stability of syndromes of mental disorders in the population.
Comprehensive Psychiatry, 41(2, suppl. 1), 122-132.
Perkonigg, A., Kessler, R. C., Storz, S., & Wittchen, H.-U. (2000). Traumatic events and
posttraumatic stress disorder in the community: Prevalence, risk factors and comorbidity. Acta
Psychiatrica Scandinavica, 101, 46-59.
Lieb, R., Wittchen, H.-U., Höfler, M., Fuetsch, M., Stein, M. B., & Merikangas, K. R. (2000). Parental
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Wittchen, H.-U., & Lieb, R. (2000). Schlussbericht zum Forschungsvorhaben "Vulnerabilitäts- und
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Wittchen, H.-U. (2000). Epidemiologie von Alkohol- und Suchtmittelmissbrauch und -abhängigkeit in
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DSM-IV social anxiety disorder associated with smoking and nicotine dependence in adolescents
and young adults? European Psychiatry, 15(1), 67-74.
Lieb, R., Pfister, H., Mastaler, M., & Wittchen, H.-U. (2000). Somatoform syndromes and disorders in
a representative population sample of adolescents and young adults: prevalence, comorbidity and
impairments. Acta Psychiatrica Scandinavica, 101(3), 194-208.
Wittchen, H.-U., R.M. Carter, and R. Lieb, Epidemiology of Generalized Anxiety Disorder. Abstract
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Schütz, C. G., R. Lieb, H. Pfister and H.-U. Wittchen (2000). "Psychiatric disorders and psychiatric
treatment in ecstasy users compared to users of other illicit and controls in a representative
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Wittchen, H.-U. and H. Sonntag, Nicotine consumption in mental disorders: A clinical
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Wittchen, H.-U., A. Perkonigg, and A. Maercker, Traumatic Events and Post-Traumatic Stress
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Lamertz, C. M. (2000). Assoziationen zwischen Psychopathologie und dem Body Mass Index bei
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Lieb, R., Isensee, B., von Sydow, K. & Wittchen, H.-U. (2000). The Early Developmental Stages of
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Lieb, R., Schuster, P., Pfister, H., Fuetsch, M., Höfler, M., Isensee, B., Müller, N., Sonntag, H., &
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Wittchen, H.-U., Kessler, R. C., Pfister, H., & Lieb, R. (2000). Why do people with anxiety disorders
become depressed? A prospective-longitudinal community study. Acta Psychiatrica Scandinavica,
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Wittchen, H.-U., Kessler, R. C., Pfister, H., Höfler, M., & Lieb, R. (2000). Why do people with
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1999
Wittchen, H.-U., Lieb, R. & Perkonigg, A. (1999). Early developmental stages of substance abuse and
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early developmental stages of anxiety and depressive disorders. Rapoport, J. L. (Hrsg.), Childhood
onset of "adult" psychopathology, clinical and research advances (259-302). Washington:
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Wittchen, H.-U., The burden and patterns of comorbidity of Generalized Anxiety Disorders. Abstract
S.17.01. European Neuropsychopharmacology, 1999. 9(suppl. 5): p. 175.
Höfler, M., Lieb, R., Perkonigg, A., Schuster, P., Sonntag, H., & Wittchen, H.-U. (1999). Covariates
of cannabis use progression in a representative population sample of adolescents: a prospective
examination of vulnerability and risk factors. Addiction, 94(11), 1679-1694.
Oldehinkel, A. J., Wittchen, H.-U., & Schuster, P. (1999). Prevalence, 20-month incidence and
outcome of unipolar depressive disorders in a community sample of adolescents. Psychological
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Perkonigg, A., & Wittchen, H.-U. (1999). Prevalence and comorbidity of traumatic events and
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Wittchen, H.-U., Stein, M. B., & Kessler, R. C. (1999). Social fears and social phobia in a community
sample of adolescents and young adults: prevalence, risk factors and comorbidity. Psychological
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1998
Reed, V., & Wittchen, H.-U. (1998). DSM-IV panic attacks and panic disorder in a community sample
of adolescents and young adults: How specific are panic attacks? Journal of Psychiatric Research, 32,
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Reed, V., Gander, F., Pfister, H., Steiger, A., Sonntag, H., Trenkwalder, C., Hundt, W., & Wittchen,
H.-U. (1998). To what degree the Composite International Diagnostic Interview (CIDI) correctly
identifies DSM-IV disorders? Testing validity issues in a clinical sample. International Journal of
Methods in Psychiatric Research, 7(3), 142_155.
Schuster, P., Lieb, R., Lamertz, C. M., & Wittchen, H.-U. (1998). Is the use of ecstasy and
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Addiction Research, 4 (1-2), 1-84.
Perkonigg, A., Lieb, R., & Wittchen, H.-U. (1998). Prevalence of use, abuse and dependence of illicit
drugs among adolescents and young adults in a community sample. European Addiction Research,
4(1-2), 58-66.
Perkonigg, A., Lieb, R., & Wittchen, H.-U. (1998). Substance use, abuse and dependence in Germany:
A review of selected epidemiological data. European Addiction Research, 4 (1-2), 8-17.
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Nelson, C. B., & Wittchen, H.-U. (1998). DSM-IV alcohol disorders in a general population sample of
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14 to 24 year olds in Germany. European Addiction Research, 4(1-2), 42-49.
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& Kessler, R. C. (1998). Comorbidity of substance use disorders with mood and anxiety disorders:
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International Diagnostic Interview (M-CIDI). Substance use sections. European Addiction Research,
4(1-2), 28-41.
Lieb, R., Lachner, G., Sonntag, H., Pfister, H., Höfler, M., Gander, F., & Wittchen, H.-U. (1998).
Familiengenetik und familiäre Sozialisation (Zwischenbericht im Rahmen des Forschungsvorhabens
"Vulnerabilitäts- und Protektionsfaktoren bei Frühstadien von Substanzmissbrauch und -abhängigkeit
- Eine Verlaufsstudie" BMFBW 01 EB9405). München: Max-Planck-Institut für Psychiatrie,
Klinische Psychologie und Epidemiologie.
Lieb, R., Mastaler, M., & Wittchen, H.-U. (1998). Gibt es somatoforme Störungen bei Jugendlichen
und jungen Erwachsenen? Erste epidemiologische Befunde der Untersuchung einer
bevölkerungsrepräsentativen Stichprobe. Verhaltenstherapie _ Praxis, Forschung, Perspektiven, 8, 8193.
Lieb, R., Pfister, H., & Wittchen, H.-U. (1998). Use, abuse and dependence of prescription drugs in
adolescents and young adults. European Addiction Research, 4(1-2), 67-74.
Lieb, R., Schuster, P., Pfister, H., Wunderlich, U., Holly, A., Mastaler, M., Sonntag, H., Gander, F.,
Höfler, M., Lachner, G., Perkonigg, A., Garczynski, E., Türk, D. & Wittchen, H.-U. (1998).
Vulnerability and protective factors in early developmental stages of substance use disorders.
European Addiction Research, 4 (4), 206-207.
Wittchen, H.-U., Höfler, M., Perkonigg, A., Sonntag, H., & Lieb, R. (1998). Wie stabil sind
Drogenkonsum und das Auftreten klinisch-diagnostisch relevanter Missbrauchs- und
Abhängigkeitsstadien bei Jugendlichen? Eine epidemiologische Studie am Beispiel von Cannabis.
Kindheit und Entwicklung, 7(4), 188-198.
Holly, A., & Wittchen, H.-U. (1998). Patterns of use and their relationship to DSM-IV abuse and
dependence of alcohol among adolescents and young adults. European Addiction Research, 4(1-2),
50-57.
Wittchen, H.-U., & Nelson, C. B. (Eds.). (1998). Early developmental stages of substance abuse. In,
(pp. 83 pages). European Addiction Research.
Wittchen, H.-U., & Hebebrand, J. (1998). Assoziationen von Körpergewicht, Body Mass Index (BMI)
und psychopathologischen Merkmalen bei 14-25jährigen (Abschlussbericht DFG WI 709/5-1/2).
Bonn: Deutsche Forschungsgemeinschaft.
Wittchen, H.-U., Lachner, G., Wunderlich, U., & Pfister, H. (1998). Test-retest reliability of the
computerized DSM_IV version of the Munich-Composite International Diagnostic Interview
(M_CIDI). Social Psychiatry and Psychiatric Epidemiology, 33, 568_578.
Wittchen, H.-U., Lachner, G., Wunderlich, U., & Pfister, H. (1998). Test-retest reliability of the
computerized DSM-IV version of the Munich-Composite International Diagnostic Interview (MCIDI). Social Psychiatry and Psychiatric Epidemiology, 33(11), 568-578.
Wittchen, H.-U., Nelson, C. B., & Lachner, G. (1998). Prevalence of mental disorders and
psychosocial impairments in adolescents and young adults. Psychological Medicine, 28, 109-126.
Wittchen, H.-U., Perkonigg, A., Lachner, G., & Nelson, C. B. (1998). Early developmental stages of
psychopathology study (EDSP) - Objectives and design. European Addiction Research, 4(1-2), 18-27.
Wittchen, H.-U., Reed, V., & Kessler, R. C. (1998). The relationship of agoraphobia and panic in a
community sample of adolescents and young adults. Archives of General Psychiatry, 55, 1017-1024.
Wunderlich, U., Bronisch, T., & Wittchen, H.-U. (1998). Comorbidity patterns in adolescents and
young adults with suicide attempts. European Archives of Psychiatry and Clinical Neuroscience,
248(2), 87-95.
1997
Wittchen, H.-U. (1997). Disko-Droge Ecstasy. Jeder sechste Konsument ist abhängig. Medical
Tribune, 4, 5.
Perkonigg, A., Beloch, E., Garczynski, E., Nelson, C. B., Pfister, H., & Wittchen, H.-U. (1997).
Prävalenz von Drogenmissbrauch und -abhängigkeit bei Jugendlichen und jungen Erwachsenen:
Gebrauch, Diagnosen und Auftreten erster Missbrauchs- und Abhängigkeitsmerkmale. Zeitschrift für
Klinische Psychologie, 26(4), 247-257.
Holly, A., Türk, D., Nelson, C. B., Pfister, H., & Wittchen, H.-U. (1997). Prävalenz von
Alkoholkonsum, Alkoholmissbrauch und -abhängigkeit bei Jugendlichen und jungen Erwachsenen.
Zeitschrift für Klinische Psychologie, 26(3), 171-178.
Wittchen, H.-U., & Pfister, H. (Eds.). (1997). DIA-X-Interviews: Manual für Screening-Verfahren und
Interview; Interviewheft Längsschnittuntersuchung (DIA-X-Lifetime); Ergänzungsheft
(DIA_X_Lifetime); Interviewheft Querschnittuntersuchung (DIA_X_12 Monate); Ergänzungsheft
(DIA_X_12Monate); PC-Programm zur Durchführung des Interviews (Längs-und
Querschnittuntersuchung); Auswertungsprogramm. Frankfurt: Swets & Zeitlinger.
Lachner, G., & Wittchen, H.-U. (1997). Familiär übertragene Vulnerabilitätsmerkmale für
Alkoholmissbrauch und -abhängigkeit. In H. Watzl & B. Rockstroh (Eds.), Abhängigkeit und
Mißbrauch von Alkohol und Drogen (pp.43-90). Göttingen: Hogrefe.
Lachner, G., & Wittchen, H.-U. (1997). Münchener Composite International Diagnostic Interview. MCIDI (Familiengenetische Version). Elternbefragung (Version 2.0, 1/97). München: Max-PlanckInstitut für Psychiatrie, Klinische Psychologie
1996
Perkonigg, A., Wittchen, H.-U., & Lachner, G. (1996). Wie häufig sind Substanzmissbrauch und abhängigkeit? Ein methodenkritischer Überblick. Zeitschrift für Klinische Psychologie, 25 (4),
280_295.
Schuster, P., & Wittchen, H.-U. (1996). Ecstasy- und Halluzinogengebrauch bei Jugendlichen. Gibt es
eine Zunahme? Verhaltenstherapie, Praxis-Forschung-Perspektiven, 6 (4), 222-233.
Wittchen, H.-U. (1996). Early developmental stages of psychopathology (EDSP). München: MaxPlanck-Institut für Psychiatrie, Klinische Psychologie und Epidemiologie.
Wittchen, H.-U. (1996). Early developmental stages of psychopathology (EDSP) (First progress
report). München: Max-Planck-Institut für Psychiatrie, Klinische Psychologie und Epidemiologie.
Wittchen, H.-U. (1996). Erster Zwischenbericht zum Forschungsvorhaben "Vulnerabilitäts_ und
Protektionsverfahren bei Frühstadien von Substanzmissbrauch und -abhängigkeit. Gefördert vom
BMFT, Laufzeit 1.7.1994_31.3.1999. Förderkennzeichen: 01 EB 9405.
Wittchen, H.-U. (1996). Vulnerabilitäts- und Protektionsfaktoren bei Frühstadien von
Substanzmissbrauch und -abhängigkeit (2. Bericht zur Zwischenbegutachtung BMFT 01 EB 9405).
München: Max-Planck-Institut für Psychiatrie, Klinische Psychologie und Epidemiologie.
Wittchen, H.-U. (1996). Vulnerabilitäts- und Protektionsverfahren bei Frühstadien von
Substanzmissbrauch und -abhängigkeit (Zwischenbericht BMFT 01 EB 9405). München: MaxPlanck-Institut für Psychiatrie, Klinische Psychologie und Epidemiologie.
Wittchen, H.-U., & Lachner, G. (1996). Klassifikation. In A. Ehlers & K. Hahlweg (Eds.),
Enzyklopädie der Psychologie Themenbereich D Praxisgebiete, Serie 2 Klinische Psychologie, Band
1, Grundlagen der Psychologie (pp. 3-67). Göttingen: Hogrefe.
Wittchen, H.-U., & Perkonigg, A. (1996). Epidemiologie psychischer Störungen. Grundlagen,
Häufigkeit, Risikofaktoren und Konsequenzen. In A. Ehlers & K. Hahlweg (Eds.), Enzyklopädie der
Psychologie, Themenbereich D Praxisgebiete. Band 1, Grundlagen der Klinischen Psychologie (pp.
69_144). Göttingen: Hogrefe.
Lachner, G., & Wittchen, H.-U. (1996). Das Composite International Diagnostic Interview Substance
Abuse Module (CIDI-SAM). In K. Mann & G. Buchkremer (Eds.), Sucht. Grundlagen, Diagnostik,
Therapie (pp. 147-156). Stuttgart: Gustav Fischer.
Wittchen, H.-U., Perkonigg, A., & Reed, V. (1996). Comorbidity of mental disorders and substance
use disorders. European Addiction Research, 2(1), 36-47.
Wittchen, H.-U., Lachner, G., & Perkonigg, A. (1996). 2. Bericht zur Zwischenbegutachtung des
Forschungsvorhabens "Vulnerabilitäts und Protektionsfaktioren bei Frühstadien von
Substanzmißbrauch und _abhängigkeit. Gefördert vom BMFT, Laufzeit 01.12.1994 - 31.03.1999.
Förderkennzeichen: BMFT 01 EB 9405.
1995
Wittchen, H.-U., Beloch, E., Garczynski, E., Holly, A., Lachner, G., Perkonigg, A., Pfütze, E.-M.,
Schuster, P., Vodermaier, A., Vossen, A., Wunderlich, U., & Zieglgänsberger, S. (1995). Gesundheit
in München Stadt und Land. Listenheft zum M-CIDI (Version 2.2 /2/95) (Eigendruck ). München:
Max-Planck-Institut für Psychiatrie, Klinische Psychologie und Epidemiologie.
Wittchen, H.-U., Beloch, E., Garczynski, E., Holly, A., Lachner, G., Perkonigg, A., Pfütze, E.-M.,
Schuster, P., Vodermaier, A., Vossen, A., Wunderlich, U., & Zieglgänsberger, S. (1995). Münchener
Composite International Diagnostic Interview (M-CIDI) (Version 2.2 /2/95) (Eigendruck ). München:
Max-Planck-Institut für Psychiatrie, Klinische Psychologie und Epidemiologie.
Wittchen, H.-U., Beloch, E., Garczynski, E., Holly, A., Lachner, G., Perkonigg, A., Pfütze, E.-M.,
Schuster, P., Vodermaier, A., Vossen, A., Wunderlich, U., & Zieglgänsberger, S. (1995). Manual zum
Münchener Composite International Diagnostic Interview (M-CIDI) (Version 2.0, 1/95) (Eigendruck).
München: Max-Planck-Institut für Psychiatrie, Klinische Psychologie und Epidemiologie.
Lachner, G., & Wittchen, H.-U. (1995). Familiär übertragene Vulnerabilitätsmerkmale für
Alkoholmißbrauch und -abhängigkeit. Zeitschrift für Klinische Psychologie, 24 (2), 118-146.
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